Pair Production of Fourth Family Charged Sleptons at e+e−e^{+}e^{-} Colliders

We study the pair production of $\tilde{l}_{4}$, which is the supersymmetric partner of the fourth family charged lepton, at the $e^{+}e^{-}$ colliders. It is shown that the investigation of this process at ILC/CLIC will give opportunity to differentiate the MSSM with three and four families.Comment: 6 pages, 2 figure

De Novo Transcriptome Assembly and Comparative Analysis Elucidate Complicated Mechanism Regulating Astragalus chrysochlorus Response to Selenium Stimuli

Astragalus species are medicinal plants that are used in the world for years. Some Astragalus species are known for selenium accumulation and tolerance and one of them is Astragalus chrysochlorus, a secondary selenium accumulator. In this study, we employed Illumina deep sequencing technology for the first time to de novo assemble A. chrysochlorus transcriptome and identify the differentially expressed genes after selenate treatment. Totally, 59,656 unigenes were annotated with different databases and 53,960 unigenes were detected in NR database. Transcriptome in A. chrysochlorus is closer to Glycine max than other plant species with 43,1 percentage of similarity. Annotated unigenes were also used for gene ontology enrichment and pathway enrichment analysis. The most significant genes and pathways were ABC transporters, plant pathogen interaction, biosynthesis of secondary metabolites and carbohydrate metabolism. Our results will help to enlighten the selenium accumulation and tolerance mechanisms, respectively in plants

Dimension-6 operator analysis of the CLIC sensitivity to new physics

We estimate the possible accuracies of measurements at the proposed CLICe+ e− collider of Higgs and W+W− production at centre-of-mass energies up to 3 TeV, incorporating also Higgsstrahlung projections at higher energies that had not been considered previously, and use them to explore the prospective CLIC sensitivities to decoupled new physics. We present the resulting constraints on the Wilson coefficients of dimension6 operators in a model-independent approach based on the Standard Model effective field theory (SM EFT). The higher centre-of-mass energy of CLIC, compared to other projects such as the ILC and CEPC, gives it greater sensitivity to the coefficients of some of the operators we study. We find that CLIC Higgs measurements may be sensitive to new physics scales Λ = O(10) TeV for individual operators, reduced to O(1) TeV sensitivity for a global fit marginalising over the coefficients of all contributing operators. We give some examples of the corresponding prospective constraints on specific scenarios for physics beyond the SM, including stop quarks and the dilaton/radion

HE-LHC: The High-Energy Large Hadron Collider – Future Circular Collider Conceptual Design Report Volume 4

In response to the 2013 Update of the European Strategy for Particle Physics (EPPSU), the Future Circular Collider (FCC) study was launched as a world-wide international collaboration hosted by CERN. The FCC study covered an energy-frontier hadron collider (FCC-hh), a highest-luminosity high-energy lepton collider (FCC-ee), the corresponding 100 km tunnel infrastructure, as well as the physics opportunities of these two colliders, and a high-energy LHC, based on FCC-hh technology. This document constitutes the third volume of the FCC Conceptual Design Report, devoted to the hadron collider FCC-hh. It summarizes the FCC-hh physics discovery opportunities, presents the FCC-hh accelerator design, performance reach, and staged operation plan, discusses the underlying technologies, the civil engineering and technical infrastructure, and also sketches a possible implementation. Combining ingredients from the Large Hadron Collider (LHC), the high-luminosity LHC upgrade and adding novel technologies and approaches, the FCC-hh design aims at significantly extending the energy frontier to 100 TeV. Its unprecedented centre-of-mass collision energy will make the FCC-hh a unique instrument to explore physics beyond the Standard Model, offering great direct sensitivity to new physics and discoveries

Evaluation of new 99mTc(CO)3 + radiolabeled glycylglycine In Vivo

PubMed: 309476762-s2.0-85075625899Background: Peptide-based agents are used in molecular imaging due to their unique properties, such as rapid clearance from the circulation, high affinity and target selectivity. Many of the radiolabeled peptides have been clinically experienced with diagnostic accuracy. The aim of this study was to investigate in vivo biological behavior of [99mTc(CO)3(H2O)3]+ radiolabeled glycylglycine (GlyGly). Methods: Glycylglycine was radiolabeled with a high radiolabeling yield of 94.69±2%, and quality control of the radiolabeling process was performed by thin layer radiochromatography (TLRC) and High-Performance Liquid Radiochromatography (HPLRC). Lipophilicity study for radiolabeled complex (99mTc(CO)3-Gly-Gly) was carried out using solvent extraction. The in vivo evaluation was performed by both biodistribution and SPECT imaging. Results: The high radiolabelling yield of 99mTc(CO)3-GlyGly was obtained and verified by TLRC and HPLRC as well. According to the in vivo results, SPECT images and biodistribution data are in good accordance. The excretion route from the body was both hepatobiliary and renal. Conclusion: This study shows that 99mTc(CO)3-GlyGly has the potential to be used as a peptide-based imaging agent. Further studies, 99mTc(CO)3-GlyGly can be performed on tumor-bearing animals. © 2019 Bentham Science Publishers.Ege Ãœniversitesi: 2012 NBE 004 Firat University Scientific Research Projects Management Unit, FÃœBAPThis study was financially supported by the Ege University Scientific Research Project numbered 2012 NBE 004 (Bornova Izmir, Turkey). The authors thank Marylou Doganavsargil for English editing of the manuscript.This study was financially supported by the Ege University Scientific Research Project numbered 2012 NBE 004 (Bornova Izmir, Turkey)

E-Cube: multi-dimensional event sequence analysis using hierarchical pattern query sharing

Due to copyright restrictions, the access to the full text of this article is only available via subscription.Many modern applications, including online financial feeds, tag-based mass transit systems and RFID-based supply chain management systems transmit real-time data streams. There is a need for event stream processing technology to analyze this vast amount of sequential data to enable online operational decision making. Existing techniques such as traditional online analytical processing (OLAP) systems are not designed for real-time pattern-based operations, while state-of-the-art Complex Event Processing (CEP) systems designed for sequence detection do not support OLAP operations. We propose a novel E-Cube model which combines CEP and OLAP techniques for efficient multi-dimensional event pattern analysis at different abstraction levels. Our analysis of the interrelationships in both concept abstraction and pattern refinement among queries facilitates the composition of these queries into an integrated E-Cube hierarchy. Based on this E-Cube hierarchy, strategies of drill-down (refinement from abstract to more specific patterns) and of roll-up (generalization from specific to more abstract patterns) are developed for the efficient workload evaluation. Our proposed execution strategies reuse intermediate results along both the concept and the pattern refinement relationships between queries. Based on this foundation, we design a cost-driven adaptive optimizer called Chase, that exploits the above reuse strategies for optimal E-Cube hierarchy execution. Our experimental studies comparing alternate strategies on a real world financial data stream under different workload conditions demonstrate the superiority of the Chase method. In particular, our Chase execution in many cases performs ten fold faster than the state-of-the art strategy for real stock market query workloads.HP Labs Innovation Research Program ; NSF ; TÜBİTA

E-Cube: multi-dimensional event sequence processing using concept and pattern hierarchies

Due to copyright restrictions, the access to the full text of this article is only available via subscription.Many modern applications including tag based mass transit systems, RFID-based supply chain management systems and online financial feeds require special purpose event stream processing technology to analyze vast amounts of sequential multi-dimensional data available in real-time data feeds. Traditional online analytical processing (OLAP) systems are not designed for real-time pattern-based operations, while Complex Event Processing (CEP) systems are designed for sequence detection and do not support OLAP operations. We will demonstrate a novel E-Cube model that combines CEP and OLAP techniques for multi-dimensional event pattern analysis at different abstraction levels. A London transit scenario will be given to demonstrate the utility and performance of this proposed technology.NS

E-Cube: multi-dimensional event sequence processing using concept and pattern hierarchies

Due to copyright restrictions, the access to the full text of this article is only available via subscription.Many modern applications including tag based mass transit systems, RFID-based supply chain management systems and online financial feeds require special purpose event stream processing technology to analyze vast amounts of sequential multi-dimensional data available in real-time data feeds. Traditional online analytical processing (OLAP) systems are not designed for real-time pattern-based operations, while Complex Event Processing (CEP) systems are designed for sequence detection and do not support OLAP operations. We will demonstrate a novel E-Cube model that combines CEP and OLAP techniques for multi-dimensional event pattern analysis at different abstraction levels. A London transit scenario will be given to demonstrate the utility and performance of this proposed technology.NS