9,135 research outputs found
SDSSJ143244.91+301435.3 at VLBI: a compact radio galaxy in a narrow-line Seyfert 1
We present VLBI observations, carried out with the European Very Long
Baseline Interferometry Network (EVN), of SDSSJ143244.91+301435.3, a radio-loud
narrow-line Seyfert 1 (RLNLS1) characterized by a steep radio spectrum. The
source, compact at Very Large Array (VLA) resolution, is resolved on the
milliarcsec scale, showing a central region plus two extended structures. The
relatively high brightness temperature of all components (5x10^6-1.3x10^8 K)
supports the hypothesis that the radio emission is non-thermal and likely
produced by a relativistic jet and/or small radio lobes. The observed radio
morphology, the lack of a significant core and the presence of a low frequency
(230 MHz) spectral turnover are reminiscent of the Compact Steep Spectrum
sources (CSS). However, the linear size of the source (~0.5kpc) measured from
the EVN map is lower than the value predicted using the turnover/size relation
valid for CSS sources (~6kpc). This discrepancy can be explained by an
additional component not detected in our observations, accounting for about a
quarter of the total source flux density, combined to projection effects. The
low core-dominance of the source (CD<0.29) confirms that
SDSSJ143244.91+301435.3 is not a blazar, i.e. the relativistic jet is not
pointing towards the observer. This supports the idea that
SDSSJ143244.91+301435.3 may belong to the "parent population" of flat-spectrum
RLNLS1 and favours the hypothesis of a direct link between RLNLS1 and compact,
possibly young, radio galaxies.Comment: 8 pages, 3 figures, accepted for publication in MNRA
IN-SILICO DESIGN, SYNTHESIS AND IN VITRO ANTITUBERCULAR ACTIVITY OF NOVEL 1, 2, 4 - TRIAZOLE DERIVATIVES
Objective: To design, synthesize and in vitro anti tubercular evaluation of some new 1,2,4–triazole derivatives.
Methods: Novel 1,2,4–triazole derivatives were designed by using various softwares like ACD Lab Chemsketch, Molinspiration, Prediction of activity spectra for substances(PASS) and Schrodinger Glide XP (Grid based ligand docking with energetics). The designed molecules having required physico-chemical properties, drug likeness and obeying Lipinski's rule of five were selected for the synthesis. The synthesized compounds were subjected to TLC, melting point determination, FTIR and 1HNMR spectroscopic studies. Antitubercular activity of selected compounds was evaluated by Resazurin microtitre assay (REMA) method.
Results: Three derivatives (MB-2, MB-8 and MB-10) were selected for the synthesis with the help of in-silico modeling. The selected derivatives were synthesized by conventional method. All the synthesized compounds showed characteristic peak in FTIR and 1HNMR spectroscopic studies. Based on the Schrodinger Glide XP score, MB-2 and MB-10 were selected for in vitro antitubercular evaluation. All the selected derivatives showed antitubercular activity, but the compound MB-2 showed significant antitubercular activity comparing with the compound MB-10.
Conclusion: These results are useful for further investigation in the future
Animasi Interaktif Pengenalan Hewan Untuk Pendidikan Anak Usia Dini
—In the current era of globalization, the development of the intellect of a child must be cultivated from an early age. This is because the brain absorption are very good at age 1-5 years. One of the things that can support a child\u27s brain absorption is through education, yet still very much children who do not understand and know about the animals that live in habitats such as land, air and sea. Incomprehension of the child to a knowledge might be due to what is being taught less attractive so that the curiosity children are reduced. One of the things that can support the development of a child\u27s brain is through interactive education. Therefore need a learning tool based interactive animation introduction of animals which aims to introduce the animal to early childhood education. In the writing of this thesis, an interactive animation created by the method of System Development Life Cycle (SDLC) waterfall that provided the software life flow approach in sequence starting from the analysis, design, coding, testing and supporting stage. Information technology-based learning methods through interactive animations have many advantages from the conventional method of learning in children ages 1-5 years, display interactive animation in education can help students in the delivery of the material and more communicative so that it can more easily remember the lesson material. Keywords: Early Childhood Education, Interactive Animation, Introduction to Animals. Intisari— Pada era globalisasi saat ini, pengembangan daya pikir terhadap seorang anak harus ditanam sejak usia dini. Hal ini disebabkan karena daya serap otak anak sangat baik pada usia 1-5 tahun. Salah satu hal yang dapat mendukung daya serap otak anak adalah dengan melalui pendidikan, namun masih sangat banyak anak-anak yang tidak mengerti dan paham tentang hewan yang hidup pada habitatnya seperti darat, udara dan laut. Ketidakpahaman anak terhadap suatu pengetahuan mungkin disebabkan karena apa yang diajarkan kurang menarik sehingga rasa ingin tahu anak berkurang. Salah satu hal yang dapat mendukung perkembangan otak anak adalah melalui pendidikan interaktif. Oleh Karena itu perlu sebuah alat pembelajaran berbasis animasi interaktif pengenalan hewan yang bertujuan untuk mengenalkan hewan untuk pendidikan anak usia dini. Dalam penulisan Pene;itian ini, animasi interaktif dibuat dengan metode System Development Life Cycle (SDLC) waterfall yang menyediakan pendekatan alur hidup perangkat lunak secara berurutan dimulai dari analisis, desain, pengkodean, pengujian dan tahap pendukung. Metode pembelajaran berbasis teknologi informasi melalui animasi interaktif memiliki banyak keunggulan dari metode belajar konvensional pada anak usia 1-5 tahun, tampilan animasi interaktif dalam dunia pendidikan dapa
On the number of epi-, mono-, and homomorphisms of groups
It is known that the number of homomorphisms from a group to a group
is divisible by the greatest common divisor of the order of and the
exponent of . We investigate the number of homomorphisms satisfying
some natural conditions such as injectivity or surjectivity. The simplest
nontrivial corollary of our results is the following fact: {\it in any finite
group, the number of generating pairs such that , is a
multiple of the greatest common divisor of 15 and the order of the group
.Comment: 5 pages. A Russian version of this paper is at
http://halgebra.math.msu.su/staff/klyachko/papers.htm . V2: minor
corrections. arXiv admin note: text overlap with arXiv:1806.0887
D-branes in Topological Minimal Models: the Landau-Ginzburg Approach
We study D-branes in topologically twisted N=2 minimal models using the
Landau-Ginzburg realization. In the cases of A and D-type minimal models we
provide what we believe is an exhaustive list of topological branes and compute
the corresponding boundary OPE algebras as well as all disk correlators. We
also construct examples of topological branes in E-type minimal models. We
compare our results with the boundary state formalism, where possible, and find
agreement.Comment: 29 pages, late
Efficient computation of the first passage time distribution of the generalized master equation by steady-state relaxation
The generalized master equation or the equivalent continuous time random walk
equations can be used to compute the macroscopic first passage time
distribution (FPTD) of a complex stochastic system from short-term microscopic
simulation data. The computation of the mean first passage time and additional
low-order FPTD moments can be simplified by directly relating the FPTD moment
generating function to the moments of the local FPTD matrix. This relationship
can be physically interpreted in terms of steady-state relaxation, an extension
of steady-state flow. Moreover, it is amenable to a statistical error analysis
that can be used to significantly increase computational efficiency. The
efficiency improvement can be extended to the FPTD itself by modelling it using
a Gamma distribution or rational function approximation to its Laplace
transform
Simulation and Analysis Chain for Acoustic Ultra-high Energy Neutrino Detectors in Water
Acousticneutrinodetectionisapromisingapproachforlarge-scaleultra-highenergyneutrinodetectorsinwater.In
this article, a Monte Carlo simulation chain for acoustic neutrino detection
devices in water will be presented. The simulation chain covers the generation
of the acoustic pulse produced by a neutrino interaction and its propagation to
the sensors within the detector. Currently, ambient and transient noise models
for the Mediterranean Sea and simulations of the data acquisition hardware,
equivalent to the one used in ANTARES/AMADEUS, are implemented. A pre-selection
scheme for neutrino-like signals based on matched filtering is employed, as it
is used for on-line filtering. To simulate the whole processing chain for
experimental data, signal classification and acoustic source reconstruction
algorithms are integrated in an analysis chain. An overview of design and
capabilities of the simulation and analysis chain will be presented and
preliminary studies will be discussed.Comment: 6 pages, 5 figures, ARENA 2012. arXiv admin note: substantial text
overlap with arXiv:1304.057
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