Aplikasi Edukasi “Music Traditional Arcade” Berbasis Android

The purpose of this study is to assist the government in introducing traditional music instruments in Indonesia to the community, especially teenagers aged from 16-20 years. Given increasingly in modern era makes people start to forget traditional music instruments and prefers modern music instruments. The method used in this research is literature study, observation, application design, and application testing that has been made. Result obtained from this study is an application that can meet the objectives of the study. The conclusion of this study is that the application gave elements and information about some traditional music instruments in interesting ways through mobile app game followed with attractive appearance and could be one way of helping the government to preserve traditional music instruments and provide insight into knowledge through the history of the instrument

Implementasi Metode User Centered Design Dalam Perancangan Aplikasi Pembelajaran Vlan & Inter-vlan Routing

This research aims to make learning application materials VLANs and Inter-VLAN Routing with User-Centered Design (UCD) methods. System was evaluated by involving students, to evaluate the level of interest and ease students' learning. The results of feedback given by the participants back to the interface implemented learning applications. In addition, the authors also do a hypothesis test to determine whether the designed application has improved the understanding of learning for the user or not. Based on the results of USAbility testing using self-reported metrics showed 72% of participants agreed that the learning system useful, 74% of participants were satisfied with the learning system that has been made, 62% of participants agreed that the learning system is easy to use, and 64% of participants agreed that the learning system provides ease of learning

The BCN Challenge to Compatibilist Free Will and Personal Responsibility

Many philosophers ignore developments in the behavioral, cognitive, and neurosciences that purport to challenge our ideas of free will and responsibility. The reason for this is that the challenge is often framed as a denial of the idea that we are able to act differently than we do. However, most philosophers think that the ability to do otherwise is irrelevant to responsibility and free will. Rather it is our ability to act for reasons that is crucial. We argue that the scientific findings indicate that it is not so obvious that our views of free will and responsibility can be grounded in the ability to act for reasons without introducing metaphysical obscurities. This poses a challenge to philosophers. We draw the conclusion that philosophers are wrong not to address the recent scientific developments and that scientists are mistaken in formulating their challenge in terms of the freedom to do otherwise

The effect of electrical neurostimulation on collateral perfusion during acute coronary occlusion

<p>Abstract</p> <p>Background</p> <p>Electrical neurostimulation can be used to treat patients with refractory angina, it reduces angina and ischemia. Previous data have suggested that electrical neurostimulation may alleviate myocardial ischaemia through increased collateral perfusion. We investigated the effect of electrical neurostimulation on functional collateral perfusion, assessed by distal coronary pressure measurement during acute coronary occlusion. We sought to study the effect of electrical neurostimulation on collateral perfusion.</p> <p>Methods</p> <p>Sixty patients with stable angina and significant coronary artery disease planned for elective percutaneous coronary intervention were split in two groups. In all patients two balloon inflations of 60 seconds were performed, the first for balloon dilatation of the lesion (first episode), the second for stent delivery (second episode). The Pw/Pa ratio (wedge pressure/aortic pressure) was measured during both ischaemic episodes. Group 1 received 5 minutes of active neurostimulation before plus 1 minute during the first episode, group 2 received 5 minutes of active neurostimulation before plus 1 minute during the second episode.</p> <p>Results</p> <p>In group 1 the Pw/Pa ratio decreased by 10 ± 22% from 0.20 ± 0.09 to 0.19 ± 0.09 (p = 0.004) when electrical neurostimulation was deactivated. In group 2 the Pw/Pa ratio increased by 9 ± 15% from 0.22 ± 0.09 to 0.24 ± 0.10 (p = 0.001) when electrical neurostimulation was activated.</p> <p>Conclusion</p> <p>Electrical neurostimulation induces a significant improvement in the Pw/Pa ratio during acute coronary occlusion.</p

Less bleeding by omitting aspirin in non-ST-segment elevation acute coronary syndrome patients: rationale and design of the LEGACY study

BackgroundEarly aspirin withdrawal, also known as P2Y12-inhibitor monotherapy, following percutaneous coronary intervention (PCI) for non-ST-segment elevation acute coronary syndrome (NSTE-ACS) can reduce bleeding without a trade-off in efficacy. Still the average daily bleeding risk is highest during the first months and it remains unclear if aspirin can be omitted immediately following PCI.MethodsThe LEGACY study is an open-label, multicenter randomized controlled trial evaluating the safety and efficacy of immediate P2Y12-inhibitor monotherapy versus dual antiplatelet therapy (DAPT) for 12 months in 3,090 patients. Patients are randomized immediately following successful PCI for NSTE-ACS to 75-100 mg aspirin once daily versus no aspirin. The primary hypothesis is that immediately omitting aspirin is superior to DAPT with respect to major or minor bleeding defined as Bleeding Academic Research Consortium type 2, 3, or 5 bleeding, while maintaining noninferiority for the composite of all-cause mortality, myocardial infarction and stroke compared to DAPT.ConclusionsThe LEGACY study is the first randomized study that is specifically designed to evaluate the impact of immediately omitting aspirin, and thus treating patients with P2Y12-inhibitor monotherapy, as compared to DAPT for 12 months on bleeding and ischemic events within 12 months following PCI for NSTE-ACS.Cardiolog

Omics-based molecular techniques in oral pathology centred cancer: Prospect and challenges in Africa

: The completion of the human genome project and the accomplished milestones in the human proteome project; as well as the progress made so far in computational bioinformatics and “big data” processing have contributed immensely to individualized/personalized medicine in the developed world.At the dawn of precision medicine, various omics-based therapies and bioengineering can now be applied accurately for the diagnosis, prognosis, treatment, and risk stratifcation of cancer in a manner that was hitherto not thought possible. The widespread introduction of genomics and other omics-based approaches into the postgraduate training curriculum of diverse medical and dental specialties, including pathology has improved the profciency of practitioners in the use of novel molecular signatures in patient management. In addition, intricate details about disease disparity among diferent human populations are beginning to emerge. This would facilitate the use of tailor-made novel theranostic methods based on emerging molecular evidences

Liens entre moustiques vecteurs et environnement: apport des méthodes de télédétection satellite

International audienc

Restenosis begets restenosis: implications for stent selection

Background: Identifying the risk for restenosis is of critical importance in the stent selection process of patients undergoing percutaneous coronary intervention (PCI). Therefore, we sought to determine if a history of clinical recurrence (CR) after PCI increases the risk of CR after treatment of a de novo lesion in another coronary artery. Methods: We retrospectively analysed all 12,763 patients who underwent PCI between 1993 and 2004 and selected patients with two or more interventions in two different native vessels. These patients were divided into two groups: patients without CR, and patients with CR after the first PCI. Clinical recurrence was defined as revascularisation of the target vessel by either PCI or CABG within one year. Results A total of 1010 patients with two or more interventions in two different native vessels were identified: 727 patients without and 283 patients with CR after the first PCI. Baseline patient characteristics and conventional risk factors were comparable between the two groups. Patients with a history of CR had a higher risk of CR after a second intervention in a second vessel (OR=3.4, 95% CI=2.3 to 4.9). A total of 112 patients also had a third intervention in a third native vessel: 12 patients with two CB, 30 patients with one CR and 70 patients with no CR after the first two interventions. CR rates in these patients were 50, 17 and 3%, respectively (p Conclusion: Patients with a history of CR have a markedly increased risk of developing CR after a second or third PCI in a different coronary artery. Therefore, in the decision-making process on whether to use a bare metal stent or drug-eluting stent, the history of CR is a simple and powerful aid. (Neth Heart J 2008;16:376-81.

PELAKSANAAN SOSIALISASI PENCEGAHAN COVID-19 BAGI MASYARAKAT DI KELURAHAN URIMESSING

Virus Corona atau yang sering disebut dengan COVID-19 adalah sebuah virus yang muncul pada akhir tahun 2019. COVID-19 adalah virus yang menyebar dengan cepat dan sulit untuk dicegah penyebarannya. Sehingga WHO resmi menetapkan COVID-19 sebagai pandemi global. Dengan cepat pemerintah Indonesia menetapkan Pembatasan Sosial Berskala Besar yang diatur dalam Peraturan Pemerintah RI No. 21 Tahun 2020. Tidak hanya itu, pemerintah juga mengeluarkan peraturan terkait dengan penerapan protokol kesehatan dalam Keputusan Menteri Kesehatan RI No. HK.01.07/MENKES/382/2020 tentang Protokol Kesehatan Bagi Masyarakat di Tempat dan Fasilitas Umum dalam Rangka Pencegahan dan Pengendalian Corona Virus Disease 2019 (COVID-19). Serta tidak hanya itu pemerintah juga menghimbau untuk segera melakukan vaksinasi berdasarkan Peraturan Menteri Kesehatan No.10 Tahun 2021 tentang Pelaksanaan Vaksinasi dalam Rangka Penanggulangan Pandemi Corona Virus Disease 2019 (COVID-19). Untuk itu tujuan dari pengabdian ini adalah untuk meningkatkan pengetahuan dan kesadaran masyarakat terkait pentingnya protokol kesehatan dan pemberian vaksinasi. Metode yang digunakan adalah pendidikan kepada masyarakat seperti memberikan pelatihan dan sosialisasi. Dan hasil pengabdian antara lain bahwa kesadaran akan protokol kesehatan dan pemberian vaksin di masyarakat kelurahan Urimessing cukup memuaskan dengan adanya sedikit perubahan, namun terlepas dari itu kesadaran akan protokol kesehatan dan pemberian vaksin masih perlu ditingkatkan