Biomass yield and fodder quality of Napier grass (Pennisetum purpureum) as affected by Pigeon pea (Cajanus cajan) intercrop and planting distance

The study sought to investigate the effect of two planting distances and Pigeon Pea (Cajanus cajan) intercrop on the biomass yield, chemical composition and in vitro organic matter digestibility (IVOMD) of Napier grass (Pennisetum purpureum). The treatments were laid in a 2x2 factorial RCBD. The factors were two planting distances (0.5x0.5 and 0.5x1m) and two levels of intercrop (Pigeon Pea intercrop and sole Napier grass). At 90-days, the grasses were harvested and biomass yield measured. The fodder was separated into leaves and stems for chemical and digestibility analysis in 2x2x2 factorial in CRD. The interaction at all levels was not significant for all the parameters. There was a significant main effect of planting distance, intercrop and botanical fraction on biomass yield, plant height, tiller number and fodder quality. Whilst biomass yield was higher (P=0.02) in the 0.5x0.5m, no significant difference was recorded in the effect of the intercrop. Whilst intercrop affected (P<0.05) IVOMD and ME, botanical fraction significantly affected DM, CP and ME. The leaf fraction had more (P<0.05) DM, CP and ME than the stem fraction. The study revealed that close planting distance enhanced biomass yield whilst Pigeon Pea intercrop and botanical fraction affected fodder quality of Napier grass

The 5-HT2A Receptor Antagonist M100907 Produces Antiparkinsonian Effects and Decreases Striatal Glutamate

5-HT plays a regulatory role in voluntary movements of the basal ganglia and has a major impact on disorders of the basal ganglia such as Parkinson's disease (PD). Clinical studies have suggested that 5-HT2 receptor antagonists may be useful in the treatment of the motor symptoms of PD. We hypothesized that 5-HT2A receptor antagonists may restore motor function by regulating glutamatergic activity in the striatum. Mice treated with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) exhibited decreased performance on the beam-walking apparatus. Peripheral administration of the 5-HT2A receptor antagonist M100907 improved performance of MPTP-treated mice on the beam-walking apparatus. In vivo microdialysis revealed an increase in striatal extracellular glutamate in MPTP-treated mice and local perfusion of M100907 into the dorsal striatum significantly decreased extracellular glutamate levels in saline and MPTP-treated mice. Our studies suggest that blockade of 5-HT2A receptors may represent a novel therapeutic target for the motor symptoms of PD

Antibiotic stewardship and its impact on antibiotic use at the child health directorate of a teaching hospital in Ghana

Purpose: The study was intended to ascertain the existence of an antibiotic stewardship programme at the Child Health Directorate of Komfo Anokye Teaching Hospital (KATH) and assess the knowledge of health professionals about the importance of the antimicrobial stewardship programme. Again, it sort to assess the experience of participants with pharmacotherapy of infections and patient outcomes with generic and innovative brands of antibiotics. The third was to assess reporting on adverse reactions and storage conditions of the antibiotics.Design/Methodology/ Approach: This was a cross-sectional study involving health professionals who participated in the provision of infectious disease management services. Eighty-eight (88) professionals were involved in the study, comprising nurses (n=51), medical doctors (n=21), pharmacists (n=8), biomedical scientists (n=5) and public health officers (n=3).Findings: The majority (75 %, n=66) reported treatment failure with generic brands of antibiotics compared to innovator brands. Thirty-four percent of the participants reported adverse drug reactions (ADRs) on antibiotic therapy to superiors instead of filling out ADR forms.Research Limitations: The study was done in one Directorate in the hospital and thus cannot be generalized to reflect the situation in all teaching hospitals in Ghana.Practical implication: The evidence obtained highlighted the need for pragmatic antimicrobial stewardship (AMS) at the directorate to help optimize the management of childhood infections and minimize the emergence and spread of antibiotic resistance.Originality/Value. This was an original project designed to generate evidence to inform interventions to promote the responsible use of antimicrobials in children

A Quality Control Scheme for a Commercial Pozzolana Plant: A Case Study of Pozzolana Ghana Ltd

A Quality control scheme was developed for a 200 ton per day commercial pozzolana plant. The scheme was evaluated for the first 34 days of production. Statistical Process Control tech­niques were specifically applied to the mechanical properties of setting times and compressive strength. Results obtained showed that pozzolana samples tested were chemically suitable with total SiO2, Al2O3 and Fe2O3 content ≥ 70%. Mechanical tests performed were mostly under control and when out-of-control, they gave valuable indication to plant malfunction or operator errors which were promptly corrected. The results of mechanical properties tested against the three major brands of cement on the Ghanaian market showed that pozzolana gave highest compressive strengths with Dangote CEM I 42.5R ranging between 21.3 MPa - 36.3 MPa at 7 days and 33.8 MPa - 45.1 MPa at 28 days whilst lowest compressive strengths were obtained with Ghacem CEM II B-L 32.5R cement ranging between 16.3 MPa – 23.6 MPa at 7 days and 23.3 MPa – 30.7 MPa at 28 days. Compressive strengths obtained with Diamond CEM II B-L 42.5N cement were average. A mean compressive strength for all brands of ce­ment of 25.2 MPa and 33.6 MPa at 7 days and 28 days respectively were obtained. Keywords: Pozzolana cement, statistical process control, Shewhart chart, compressive strength, setting tim

Resourcing Small and Medium Enterprises: Owners Willingness to Seek Funding From Banks in Ghana

One of the most important resources required by owners of Small and Medium Enterprises (SMEs) in their operation is capital. When internal funds become inadequate for the running of the business, the need arises for owners to seek external funding to support what is generated internally. Many SMEs in Ghana have not utilized the banks in their pursuit for external funding and that is a source of worry for both parties. This study was then motivated to find out the factors contributing to this action. A sample size of 125 SME owners was made to respond to questions pertaining to the objective of the study. The data generated was analyzed using an Econometric views regression model called the probit model and it turned out that, four out of the eight variables used in the study had significant effect on the willingness of SMEs owners to seek funding from banks. The study therefore concluded among other things that, firms prefer to deal with banks they are not familiar with and also innovative oriented firms are not necessarily large firms. Keywords: Resourcing, willingness, funding, banks, SME, internal, external, fundin

Women's autonomy in healthcare decision-making and healthcare seeking behaviour for childhood illness in Ghana: Analysis of data from the 2014 Ghana Demographic and Health Survey.

IntroductionThe capacity of women to decide on their healthcare plays a key role in their health. In this study, we examined the association between women's healthcare decision-making capacity and their healthcare seeking behaviour for childhood illnesses in Ghana.Materials and methodsWe used data from the 2014 Ghana Demographic and Health Survey. A total sample of 2,900 women with children less than 5 years was used for the analysis. Data were processed and analysed using STATA version 14.0. Chi-square test of independence and binary logistic regression were carried out to generate the results. Statistical significance was pegged at 95% confidence intervals (CIs). We relied on the 'Strengthening the Reporting of Observational Studies in Epidemiology' (STROBE) statement in writing the manuscript.ResultsOut of the 2,900 women, approximately 25.7% could take healthcare decisions alone and 89.7% sought healthcare for childhood illnesses. Women who decided alone on personal healthcare had 30% reduced odds of seeking healthcare for childhood illnesses compared to those who did not decide alone [AOR = 0.70, CI = 0.51-0.97]. With age, women aged 45-49 had 69% reduced odds of seeking healthcare for childhood illnesses compared to those aged 25-29 [AOR = 0.31, CI = 0.14-0.70]. Women from the Northern and Upper West regions had 72% [AOR: 0.28, CI: 0.11-0.70] and 77% [AOR: 0.23, CI: 0.09-0.58] reduced odds of seeking healthcare for childhood illnesses respectively, compared to those from the Western region.ConclusionGhanaian women with autonomy in healthcare decision-making, those who were older and those from the Northern and Upper West regions were less likely to seek healthcare for childhood illness. To reduce childhood mortalities and morbidities in Ghana, we recommend educating women such as those who take healthcare decisions alone, older women and women from deprived regions like the Northern and Upper West regions on the need to seek healthcare for childhood illnesses

Use of the Triple-Layer Hermetic Bag against the Maize Weevil, Sitophilus Zeamais (Mots) in Three Varieties of Maize

Maize ranks with wheat and rice as one of the world’s chief grain crops. However, the safety of this important food crop is threatened by pests such as insects, rodents and moulds which results from inappropriate storage methods. Insect pest infestation accounts for about 20-50% of all food crop losses. This study was carried under ambient laboratory conditions of 32± 2oC and 72-88% r.h to determine the effectiveness of the triple-layer hermetic bag in controlling the maize weevil Sitophilus zeamais (Mot) on three varieties of maize (Obatampa, Abrodenkye and Kamangkpong). Five (5) kilograms of each variety with three replicates were infested with 50 S. zeamais and stored for three (3) months in three different types of bags (hermetic, Polypropylene and Jute). Destructive sampling was done monthly to determine the moisture content, viability of each variety and weight loss after storage. Percentage damage of grain due to S. zeamais was assessed on the different types of storage bags. The results show that the high yielding Obatampa was more susceptible to S. zeamais than the two local varieties; Abrodenkye and Kamangkpong. Damage, weight loss and germination rates were significantly (p  higher in the polypropylene and jute bags than the hermetic bags. These were also dependent on the length of storage. The triple-layer hermetic bags were effective against S. zeamais and could be used for storage of maize. Keywords: Maize weevil, Sitophilus zeamais; Triple-layer hermetic bag; Polypropylene; Jute

Female genital mutilation/cutting in Sierra Leone: are educated women intending to circumcise their daughters?

BACKGROUND:Female genital mutilation/cutting (FGM/C) has been recognized as a gross violation of human rights of girls and women. This is well established in numerous international legal instruments. It forms part of the initiation ceremony that confers womanhood in Sierra Leone. Girls and women who are subjected to this practice are considered to be ready for marriage by their parents and communities and are rewarded with celebrations, gifts, and public recognition. Following this, we examined the relationship between education and women's FGM/C intention for their daughters in Sierra Leone. METHODS:We used cross-sectional data from the women's file of the 2013 Sierra Leone Demographic and Health Survey (SLDHS) to explore the influence of education on FGM/C intention among women in the reproductive age (15-49). A sample of 6543 women were included in the study. Our analysis involved descriptive computation of education and FGM/C intention. This was followed by a two-level multilevel analysis. Fixed effect results were reported as Odds Ratios and Adjusted Odds Ratios with their respective credible intervals (CrIs) whilst results of the random effects were presented as variance partition coefficients and median odds ratios. RESULTS:Our findings showed that women who had no formal education were more likely to intend to circumcise their daughters [aOR = 4.3, CrI = 2.4-8.0]. Among the covariates, women aged 20-24 [aOR = 2.3, CrI = 1.5-3.4] were more likely to intend to circumcise their daughters compared to women between 45 and 49 years old. Poorest women were more likely to report intention of circumcising their daughters in the future compared with the richest [aOR = 2.1, CrI = 1.3-3.2]. We noted that, 63.3% of FGM/C intention in Sierra Leone is attributable to contextual factors. CONCLUSION:FGM/C intention is more common among women with no education, younger women as well as women in the lowest wealth category. We recommend segmented female-child educational and pro-poor policies that target uneducated women in Sierra Leone. The study further suggests that interventions to end FGM/C need to focus on broader contextual and social norms in Sierra Leone