A NOVEL SEMANTIC SIMILARITY SCORE FOR PROTEIN DATA ANALYSIS

oai:ojs2.ctrj.in:article/1Aim: A similarity evaluation measure for Gene Ontology GO terms is developed. Results: The proposed method takes into account the semantics hidden in ontologies or the term level information content, membership of term, and topology-based similarity measures. The proposed method is evaluated on positive and negative dataset of UniProt, Protein family clans and the Pearson’s correlation with other existing methods. Conclusion: The experimental results exhibited a major supremacy of the proposed method over other semantic similarity measures. HIGHLIGHTS:1. An improved approach for semantic similarity evaluation for GO terms based on the information content and the topological factors is developed.2. The proposed method shows highest correlation for MF (Molecular Function) ontology

A review of aligners for protein protein interaction networks

Protein Protein Interaction (PPI) can be considered as network. Alignment is the process of mapping nodes from one network to another network. The main objective of network alignment is to identify small, well defined interactome units such as protein complexes or conserved pathways that are analogous in the input network. Network alignment uncovers the relationship between protein complexes and functions. Similarity between two graph structures can be identified by evaluating the topology. Network alignment identifies either topological or sequential similarity. Gene annotations reveal the functional or sequential similarity and it can be evaluated based on semantic similarity. In this paper, we review the various network aligners and classify them according to the methodologies. We discuss the different evaluation metrics and the popular databases of protein interactions

An internet of things enabled framework to monitor the lifecycle of Cordyceps sinensis mushrooms

Cordyceps sinensis is an edible mushroom found in high quantities in the regions of the Himalayas and widely considered in traditional systems of medicine. It is a non-toxic remedy mushroom and has a high measure of clinical medical benefits including cancer restraint, high blood pressure, diabetes, asthma, depression, fatigue, immune disorder, and many infections of the upper respiratory tract. The cultivation of this kind of mushroom is limited to the region of the Sikkim and to cultivate in the other regions of the country, they are need of investigation and prediction of cordyceps sinensis mushroom lifecycle. From the studies, it is concluded that the precision-based agriculture techniques are limitedly explored for the prediction and growth of Cordyceps sinensis mushrooms. In this study, an internet of things (IoT) inspired framework is proposed to predict the lifecycle of Cordyceps sinensis mushrooms and also provide alternate substrate to cultivate Cordyceps sinensis mushrooms in other parts of the country. As a part of lifecycle prediction, a framework is proposed in this study. According to the findings, an IoT sensor-based system with the ideal moisture level of the mushroom rack is required for the growth of Cordyceps sinensis mushrooms

CONTRIVANCE FOR SMART MANUFACTURING INTENSIFIED APPLICATION BASED ON CLOUD COMPUTING

Carrying out clever assembling administrations on plant wide edge gadgets associated with creation hardware effectively so those assembling administrations are pluggable, attachment and-play, and reasonable through the organization is a difficult undertaking and is exceptionally advantageous for working with understanding a shrewd plant. Cloud producing is arising as a key empowering influence for assembling organizations to convey exceptionally adjustable administrations over the Web. This paper expects to research how cloud fabricating frameworks can work with compelling assistance arranged business i.e., smart manufacturing. This framework proposes a cloud-based pluggable assembling administration conspire by utilizing cloud computing with security. By utilizing a two-layer hierarchical architecture of service mechanism, the assembling administrations can be inherent to the type of pluggable application module. &nbsp