Archaeological Studies for the San Antonio Channel Improvement Project, including Investigations at Guenther\u27s Upper Mill (41BX342)

Under Contract No. DACW63-81-C-0022 to the Department of the Army, Corps of Engineers, Fort Worth District, the Center for Archaeological Research, The University of Texas at San Antonio, in the spring of 1981, conducted historic research and survey in the areas to be affected by the San Antonio Channel Improvement Project. In the summer of 1981, extensive archaeological testing and excavation were done to determine the extent of the structural remains on the sites of Guenther\u27s Upper Mill and the Stribling House. In the spring and summer of 1982, the Center documented the removal and replacement of the mill\u27s west wall. As a result of the investigations, it can now be affirmed that most of the foundation of the east section of the mill is still present beneath the ground. The main foundation walls are made of cut limestone and measure two feet in thickness, except for the west wall which is three feet thick. Of the other buildings at various times related to the mill, only portions of a late (ca. 1910) stone and cement foundation for the Reigler Creamery still remain in the ground. The survey revealed no other cultural resources to be affected by the project

Archaeological Testing at Goliad State Park, Goliad County, Texas

In December 1996, the Center for Archaeological Research (CAR) of The University of Texas at San Antonio entered into a contract with the Texas Parks and Wildlife Department to conduct archaeological investigations at Mission Espiritu Santo in Goliad State Park. On December 17, 1996, a seven-member field crew from CAR excavated 32 shovel tests along the proposed trench for replacement of existing park water and electrical lines between the mission compound and the camping area. Artifacts recovered from the shovel tests include Spanish colonial ceramics, glass, metal, stone tools and debitage, and a large quantity of animal bone. Most of the artifacts were recovered from the shovel test pits near the mission wall. Any new trenching in this area would disturb possible intact Colonial deposits. Very few artifacts were recovered from the remainder of the proposed trench line

A Guide to Ceramics from Spanish Colonial Sites in Texas

The descriptions of ceramic types in this publication are compiled primarily as an aid to archaeologists working at missions and presidios in Texas, though it will also help those investigating town and ranch sites occupied during the eighteenth century. It was written with the help of numerous site reports done by archaeologists throughout the twentieth century who have valiantly wrestled with the problems of type identification and dating. The senior author has had the privilege of working with many of them throughout this period, and has developed an intense interest in ceramic identification. Additional help has come from researchers who have created and refined the ceramic typology over the years, from John Goggin in 1968 to Kathleen Deagan in 1987. The research of Florence and Robert Lister (1974, 1975, 1976a, 1976b, 1978) has contributed priceless information on the identification and origins of majolicas

Glucosamine hydrochloride for the treatment of osteoarthritis symptoms

Osteoarthritis is the most common arthritis in the world. It affects millions of people with age being the greatest risk factor for developing the disease. The burden of disease will worsen with the aging of the world’s population. The disease causes pain and functional disability. The direct costs of osteoarthritis include hospital and physician visits, medications, and assistive services. The indirect costs include work absences and lost wages. Many studies have sought to find a therapy to relieve pain and reduce disability. Glucosamine hydrochloride (HCl) is one of these therapies. There are limited studies of glucosamine HCl in humans. Although some subjects do report statistically significant improvement in pain and function from products combining glucosamine HCl and other agents, glucosamine HCl by itself appears to offer little benefit to those suffering from osteoarthritis

Women as a Force Multiplier for Bringing Nuclear Forensic Capabilities to the International Stage

In 2009, the US Department of Energy National Nuclear Security Administration’s (NNSA’s) Defense Nuclear Nonproliferation Program initiated a new nuclear forensics outreach effort under its Confidence Building Measures Program. Little did they know that the timing could not have been better. This article focuses on the early years (2009–2015) of the NNSA’s international nuclear forensics outreach, specifically the efforts and experiences of the women who helped establish this program, building it from a fledgling, bilateral effort into an enduring technical capacity provider engaging with dozens of countries and multilateral organizations. At the onset of the program, nuclear forensics was an emerging priority within the US Government and receiving increased focus from international organizations through high-level diplomatic efforts such as the Nuclear Security Summit and Global Initiative to Combat Nuclear Terrorism. Additionally, working-level initiatives were gaining traction through the International Atomic Energy Agency and the Nuclear Forensics International Technical Working Group. Over the next 6 years, a small team comprising a uniquely large number of women NNSA federal, contract, and national laboratory staff served as key leaders engaging with the international community to strengthen global technical nuclear forensics capacity and best practices. The program continues today under the Nuclear Smuggling Detection and Deterrence Program as Investigation Support. The experiences shared here detail a unique time period when the new technical discipline of nuclear forensics was beginning to mature and gain international traction. The authors have made every effort to remember history correctly and be as inclusive as possible. A wealth of training, guidance, and exercise documentation was developed in the 2009–2015 time frame, much of which still serves as the foundation for today’s even more extensive program and community of dedicated technical and diplomatic practitioners

Contributions of VLDLR and LRP8 in the establishment of retinogeniculate projections

Background Retinal ganglion cells (RGCs), the output neurons of the retina, project to over 20 distinct brain nuclei, including the lateral geniculate nucleus (LGN), a thalamic region comprised of three functionally distinct subnuclei: the ventral LGN (vLGN), the dorsal LGN (dLGN) and the intergeniculate leaflet (IGL). We previously identified reelin, an extracellular glycoprotein, as a critical factor that directs class-specific targeting of these subnuclei. Reelin is known to bind to two receptors: very-low-density lipoprotein receptor (VLDLR) and low-density lipoprotein receptor-related protein 8 (LRP8), also known as apolipoprotein E receptor 2 (ApoER2). Here we examined the roles of these canonical reelin receptors in retinogeniculate targeting. Results To assess the roles of VLDLR and LRP8 in retinogeniculate targeting, we used intraocular injections of fluorescently conjugated cholera toxin B subunit (CTB) to label all RGC axons in vivo. Retinogeniculate projections in mutant mice lacking either VLDLR or LRP8 appeared similar to controls; however, deletion of both receptors resulted in dramatic defects in the pattern of retinal innervation in LGN. Surprisingly, defects in vldlr−/−;lrp8−/− double mutant mice were remarkably different than those observed in mice lacking reelin. First, we failed to observe retinal axons exiting the medial border of the vLGN and IGL to invade distant regions of non-retino-recipient thalamus. Second, an ectopic region of binocular innervation emerged in the dorsomedial pole of vldlr−/−;lrp8−/− mutant dLGN. Analysis of retinal projection development, retinal terminal sizes and LGN cytoarchitecture in vldlr−/−;lrp8−/− mutants, all suggest that a subset of retinal axons destined for the IGL are misrouted to the dorsomedial pole of dLGN in the absence of VLDLR and LRP8. Such mistargeting is likely the result of abnormal migration of IGL neurons into the dorsomedial pole of dLGN in vldlr−/−;lrp8−/− mutants. Conclusions In contrast to our expectations, the development of both the LGN and retinogeniculate projections appeared dramatically different in mutants lacking either reelin or both canonical reelin receptors. These results suggest that there are reelin-independent functions of VLDLR and LRP8 in LGN development, and VLDLR- and LRP8-independent functions of reelin in class-specific axonal targeting

Laredo, Texas: Gateway Community on the Texas Borderlands, Archaeological and Historical Investigations for the Laredo City Toll Plaza

In July 1980, the Center for Archaeological Research, The University of Texas at San Antonio, conducted archaeological and historical investigations at sites designated as 41 WB 36,41 WB 37, and 41 WB 38, which are located in a residential district on the east side of the town of Laredo, Texas. These sites are represented by late historic foundations which were uncovered after a group of houses were razed to make way for a new toll bridge complex to facilitate international travel between the United States and the Republic of Mexico. A short history of Laredo and of the four house foundations excavated by the Center for Archaeological Research is presented in this report. The archaeological investigations of the structures and their associated artifacts are described and interpreted to provide a better understanding of sociocultural activities in Laredo from early historic times to the present

Solid State Proton Spin Relaxation and \u3ci\u3et\u3c/i\u3e-Butyl and Methyl Group Reorientation in 1-Bromo-2,4,6-Tri-\u3ci\u3et\u3c/i\u3e-Butylbenzene

We have used the solid state proton spin relaxation technique to investigate the barriers for methyl and t-butyl group reorientation in polycrystalline 1-bromo-2,4,6-tri-t-butylbenzene. The barriers in the range of 15-19 kJ/mol (3-5 kcal/mol) are compared with those found in related molecules. It is shown that the neighboring ring bromine atom has an effect on the barrier for t-butyl group reorientation similar to that of a neighboring hydrogen atom despite the significantly larger van der Waals\u27 radius of a bromine atom. This most likely occurs because of the relatively long carbon-bromine bond, the distorted ring geometry, and the relatively high polarizability of bromine. In addition, the barriers for methyl group reorientation, about 16 kJ/mol, seem to be largely intra-t-butyl in origin

Bearing area curve based partitioning for the verification of theoretical supplemental geometry on additively manufactured lattice structures

The geometrical qualification of additively manufactured lattice structures has largely focused on the mea-surement of strut diameter, form variations, and surface texture. However, the exterior surfaces of the lattice structure, defined through theoretical supplemental geometry, are critical surfaces that dictate the contact area of the structure on other components within assemblies. Form variations on these surfaces complicate the measurement process by adding ambiguity into what surfaces of the component belong to the controlled ge-ometry. Previous works have developed novel methods to improve data extraction for the measurement of these surfaces using computer aided design (CAD) data for various lattice structures. This work presents an adaptation of these methods to work with additively manufactured (AM) geometries, specifically designing the methodology to account for the form variations between lattice struts. The presented results show the applicability of these methods to AM lattice structures for the measurement of form defined by a theoretical supplemental surface

Solid State Proton Spin Relaxation and \u3ci\u3et\u3c/i\u3e-Butyl and Methyl Group Reorientation in 1-Bromo-2,4,6-Tri-\u3ci\u3et\u3c/i\u3e-Butylbenzene

We have used the solid state proton spin relaxation technique to investigate the barriers for methyl and t-butyl group reorientation in polycrystalline 1-bromo-2,4,6-tri-t-butylbenzene. The barriers in the range of 15-19 kJ/mol (3-5 kcal/mol) are compared with those found in related molecules. It is shown that the neighboring ring bromine atom has an effect on the barrier for t-butyl group reorientation similar to that of a neighboring hydrogen atom despite the significantly larger van der Waals\u27 radius of a bromine atom. This most likely occurs because of the relatively long carbon-bromine bond, the distorted ring geometry, and the relatively high polarizability of bromine. In addition, the barriers for methyl group reorientation, about 16 kJ/mol, seem to be largely intra-t-butyl in origin