1,176 research outputs found

    Der Stakeholderdialog zwischen Regulierung und Rhetorik: eine empirische Studie der dargestellten Dialogorientierung in deutschen und dänischen Geschäftsberichten

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    "Ausgehend von den Rahmenbedingungen der Geschäftsberichterstattung, u.a. von Corporate Governance Richtlinien, wird untersucht, inwieweit und wie sich deutsche und dänische Unternehmen der Chemischen Industrie nach außen als dialogorientiert darstellen. Darüber hinaus wird auf Dilemmas bei der Darstellung des Stakeholderdialogs und auf ungenutzte Potenziale dieser Darstellung als Differenzierungsparameter gegenüber der Konkurrenz aufmerksam gemacht." (Autorenreferat)"Stakeholder dialogues are part of Corporate Governance Regulations and therefore a management instrument that many companies deal with and communicate about. This article investigates how German and Danish chemical companies present and construct dialogue with stakeholders in their annual reports. This entails analyzing, first, to what extent stakeholder dialogue is articulated, second bow the stakeholder dialogue is evaluated linguistically and, third, what approaches to stakeholder dialogue are expressed in the reports. Moreover, the author addresses some possibilities for better communication about stakeholder dialogue as a means of differentiation and corporate identity profiling in relation to competitors." (author's abstract

    A non-synonymous single-nucleotide polymorphism in the gene encoding Toll-like Receptor 3 (TLR3) is associated with sero-negative Rheumatoid Arthritis (RA) in a Danish population

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    BACKGROUND: It has been suggested that polymorphisms in Toll-like Receptors (TLRs) are associated with Rheumatoid Arthritis (RA), but the implicated alleles have differed between studies. The aim of this investigation was to explore whether polymorphisms of TLR genes are associated with RA in a predominantly Caucasian population from Denmark using a case–control approach. FINDINGS: DNA samples (3 university hospital outpatient clinics) were obtained from patients with RA (n = 704) and healthy controls (n = 639) in a Danish population. TLR single nucleotide polymorphisms (SNPs) were selected based on the previously reported associations with chronic autoimmune diseases. Genotyping for the TLR SNPs was performed using Sequenom Multiplex technology. We identified one SNP in TLR3, [(rs3775291, P = 0.02, OR (95% CI) 1.31 (1.1087-1.5493)] significantly associated with the whole RA cohort. Subgroup analysis according to IgM rheumatoid factor (RF) and anti-cyclic citrinullated peptide (CCP) status suggested a significant association of sero-negative RA with the rs3775291 A allele and disease activity in this subset. CONCLUSION: These observations on a RA population of Danish ancestry suggest that variations in the TLR3 locus may be implicated in the pathogenesis of sero-negative RA. Since this TLR3 SNP has previously been associated with systemic lupus erythematous (SLE), the present findings support the notion that TLR3 genetic variants may represent a common risk factor in different chronic inflammatory conditions, including RA and SLE

    Parity, mode of birth, and long-term gynecological health: A follow-up study of parous and nonporous women in the Australian Longitudinal Study on Women's Health cohort

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    Background:Although gynecological health issues are common and cause considerable distress, little is known about their causes. We examined how birth history is associated with urinary incontinence (UI), severe period pain, heavy periods, and endometriosis. Methods:We studied 7700 women in the Australian Longitudinal Study on Women's Health with an average follow-up of 10.9 years after their last birth. Surveys every third year provided information about birth history and gynecological health. Logistic regression was used to estimate how parity, mode of birth, and vaginal tears were associated with gynecological health issues. Presented results are adjusted odds ratios (OR) with 95% confidence intervals. Results:UI was reported by 16%, heavy periods by 31%, severe period pain by 28%, and endometriosis by 4%. Compared with women with two children, nonparous women had less UI (OR 0.35 [0.26–0.47]) but tended to have more endometriosis (OR 1.70 [0.97–2.96]). Also, women with only one child had less UI (OR 0.77 [0.61–0.98]), but more severe period pain (OR 1.24 [1.01–1.51]). Women with 4+ children had more heavy periods (OR 1.42 [1.07–1.88]). Compared with women with vaginal birth(s) only, women with only cesarean sections or vaginal birth after cesarean section had less UI (ORs 0.44 [0.34–0.58] and 0.55 [0.40–0.76]), but more endometriosis (ORs 1.91 [1.16–3.16] and 2.31 [1.25–4.28]) and heavy periods (ORs 1.21 [1.00–1.46] and 1.35 [1.06–1.72]). Vaginal tear(s) did not increase UI after accounting for parity and birth mode. Conclusion:While women with vaginal childbirth(s) reported more urinary incontinence, they had less menstrual complaints and endometriosis.</p
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