21 research outputs found
Stolonicaulon: A Section-Puzzle within Marsupella (Gymnomitriaceae, Marchantiophyta)
Marsupella sect. Stolonicaulon is not speciose and is a commonly neglected section within the genus, which currently includes three species with somewhat similar morphologies (wiry shoots with distanced leaves) and distributions in the mountains of tropical and subtropical regions (SE (Southeast) Asia, the Venezuelan Andes, and the high mountains of SE Brazil). After studying materials that were found to be dissimilar to the βtraditionalβ Marsupella that were collected in the last decade by the authors of this article, it was found that these plants belong to three new-for-science species, and all of these species should be included in Marsupella sect. Stolonicaulon. The newly described species have expanded the boundaries of morphological variability, not only for the section itself, but also for the genus based on two findings: (1) the leaves of Marsupella sect. Stolonicaulon can be either appressed and entire or spaced and deeply divided (thus, the plants could occasionally be similar to Cephaloziella or Anastrophyllum); (2) some species of the section possess regular underleaf production. The first discovery of regular underleaves in Marsupella, as noted in two of the three newly described taxa, is the main morphological novelty described in this paper. The development of regular underleaves is a presumable relict character that brings Marsupella closer to Nardia, which was recently transferred to the Gymnomitriaceae and occupies an isolated position within its own subfamily, Nardioideae
A clinical case of post-COVID-19 myoendocarditis and arrhythmic syndrome at the outpatient stage
Background: Infection with the SARS-CoV-2 virus entails the development of complications which affect the prognosis of the underlying disease. More than 40% of COVID-19 complications represent diseases of the cardiovascular system, most of which are the rhythm and conduction disturbances. In order to avoid these complications, it is necessary to detect cases of infection in a timely manner at the outpatient stage. Clinical case description: A 40-year-old patient came to the clinic with complaints of interruptions in the heart rhythm that appeared after the coronavirus infection. The laboratory examination (CBC) revealed signs of systemic inflammation (leukocytosis 12.6Γ109 U/l; erythrocyte sedimentation rate 18 mm/h, C-reactive protein 18 mg/l); the instrumental examination of the heart revealed the rhythm disturbances in the form of frequent ventricular ectopic activity and weakness of the SA node. The patient received propafenone (150 mg, 3 times a day) as a therapy with a positive effect. Against the background of improvement in the patientβs condition and despite the history of myocarditis and a positive result of enzyme immunoassay for antibodies to SARS-CoV-2 (IgG, 10 BAU/ml), the patient was prescribed immunization with the CoviVac vaccine. After the immunization, the condition worsening was observed in the form of an increase in the rhythm disturbances, which required an inpatient treatment. A clinical diagnosis of recurrent ventricular arrhythmia β ventricular extrasystole was established, and the therapy was corrected. The outcome was favorable. Conclusion: Myocarditis is one of the most common complications of SARS-CoV-2 and should be kept in mind at all stages of medical care. This clinical case demonstrates the importance of the correct diagnosis and treatment of post-COVID myocarditis, as well as the need to assess contraindications for SARS-CoV-2 vaccination in patients with cardiac complications
ΠΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠ΅ ΠΊΠ°ΡΠ΅ΡΡΠ²Π° ΡΠΎΡΡΠ°ΡΠ½ΡΡ ΠΌΠΈΠ½Π΅ΡΠ°Π»ΡΠ½ΡΡ ΡΠ΄ΠΎΠ±ΡΠ΅Π½ΠΈΠΉ
ΠΠΈΠΏΠ»ΠΎΠΌΠ½Π°Ρ ΡΠ°Π±ΠΎΡΠ° ΠΏΠΎΡΠ²ΡΡΠ΅Π½Π° Π°Π½Π°Π»ΠΈΠ·Ρ ΡΠΎΡΡΠ°Π²Π° ΠΈ ΡΠ²ΠΎΠΉΡΡΠ² ΡΠΎΡΡΠ°ΡΠ½ΡΡ
ΠΌΠΈΠ½Π΅ΡΠ°Π»ΡΠ½ΡΡ
ΡΠ΄ΠΎΠ±ΡΠ΅Π½ΠΈΠΉ.
ΠΡΠΈ Π²ΡΠΏΠΎΠ»Π½Π΅Π½ΠΈΠΈ Π΄Π°Π½Π½ΠΎΠΉ ΡΠ°Π±ΠΎΡΡ Π² ΠΊΠ°ΡΠ΅ΡΡΠ²Π΅ ΠΎΠ±ΡΠ°Π·ΡΠ° ΡΠΎΡΡΠ°ΡΠ½ΠΎΠ³ΠΎ ΠΌΠΈΠ½Π΅ΡΠ°Π»ΡΠ½ΠΎΠ³ΠΎ ΡΠ΄ΠΎΠ±ΡΠ΅Π½ΠΈΡ Π±ΡΠ» Π²ΡΠ±ΡΠ°Π½ ΠΌΠΎΠ½ΠΎΠΊΠ°Π»ΡΡΠΈΠΉΡΠΎΡΡΠ°Ρ. Π ΠΊΠ°ΡΠ΅ΡΡΠ²Π΅ ΠΎΡΠ½ΠΎΠ²Π½ΡΡ
Π°Π½Π°Π»ΠΈΠ·ΠΈΡΡΠ΅ΠΌΡΡ
ΠΏΠΎΠΊΠ°Π·Π°ΡΠ΅Π»Π΅ΠΉ ΠΊΠ°ΡΠ΅ΡΡΠ²Π° Π² ΡΠ°Π±ΠΎΡΠ΅ Π±ΡΠ»ΠΈ Π²ΡΠ±ΡΠ°Π½Ρ ΡΠ»Π΅Π΄ΡΡΡΠΈΠ΅ ΠΏΠΎΠΊΠ°Π·Π°ΡΠ΅Π»ΠΈ: ΡΠΎΠ΄Π΅ΡΠΆΠ°Π½ΠΈΠ΅ ΠΊΠ°Π»ΡΡΠΈΡ, ΡΠΎΠ΄Π΅ΡΠΆΠ°Π½ΠΈΠ΅ ΡΠΎΡΡΠΎΡΠ°, ΡΠΎΠ΄Π΅ΡΠΆΠ°Π½ΠΈΠ΅ Π²ΠΎΠ΄Ρ, ΡΠ, ΡΠΎΠ΄Π΅ΡΠΆΠ°Π½ΠΈΠ΅ ΠΌΡΡΡΡΠΊΠ°. ΠΠΏΡΠ΅Π΄Π΅Π»Π΅Π½ΠΈΠ΅ Π²ΡΠ±ΡΠ°Π½Π½ΡΡ
ΠΏΠΎΠΊΠ°Π·Π°ΡΠ΅Π»Π΅ΠΉ ΠΏΡΠΎΠ²ΠΎΠ΄ΠΈΠ»ΠΎΡΡ ΠΌΠ΅ΡΠΎΠ΄Π°ΠΌΠΈ, ΡΠ΅ΠΊΠΎΠΌΠ΅Π½Π΄ΠΎΠ²Π°Π½Π½ΡΠΌΠΈ Π½ΠΎΡΠΌΠ°ΡΠΈΠ²Π½ΡΠΌΠΈ Π΄ΠΎΠΊΡΠΌΠ΅Π½ΡΠ°ΠΌΠΈ Π½Π° ΠΈΡΡΠ»Π΅Π΄ΡΠ΅ΠΌΡΡ ΠΏΡΠΎΠ΄ΡΠΊΡΠΈΡ, Π° ΡΠ°ΠΊΠΆΠ΅, ΡΠΈΠ·ΠΈΠΊΠΎ-Ρ
ΠΈΠΌΠΈΡΠ΅ΡΠΊΠΈΠΌΠΈ ΠΌΠ΅ΡΠΎΠ΄Π°ΠΌΠΈ Π°Π½Π°Π»ΠΈΠ·Π° Π² ΠΊΠ°ΡΠ΅ΡΡΠ²Π΅ ΠΌΠ΅ΡΠΎΠ΄ΠΎΠ² ΡΡΠ°Π²Π½Π΅Π½ΠΈΡ. ΠΠ°Π½Π½Π°Ρ Π΄ΠΈΠΏΠ»ΠΎΠΌΠ½Π°Ρ ΡΠ°Π±ΠΎΡΠ° ΡΠΎΡΡΠΎΠΈΡ ΠΈΠ· Π²Π²Π΅Π΄Π΅Π½ΠΈΡ, Π»ΠΈΡΠ΅ΡΠ°ΡΡΡΠ½ΠΎΠ³ΠΎ ΠΎΠ±Π·ΠΎΡΠ°, Ρ
Π°ΡΠ°ΠΊΡΠ΅ΡΠΈΡΡΠΈΠΊΠΈ ΠΌΠΎΠ½ΠΎΠΊΠ°Π»ΡΡΠΈΠΉΡΠΎΡΡΠ°ΡΠ°, ΠΌΠ΅ΡΠΎΠ΄ΠΎΠ² Π°Π½Π°Π»ΠΈΠ·Π° ΠΌΠΎΠ½ΠΎΠΊΠ°Π»ΡΡΠΈΠΉΡΠΎΡΡΠ°ΡΠ°, ΡΠΊΡΠΏΠ΅ΡΠΈΠΌΠ΅Π½ΡΠ°Π»ΡΠ½ΠΎΠΉ ΡΠ°ΡΡΠΈ, ΠΎΠ±ΡΡΠΆΠ΄Π΅Π½ΠΈΡ ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΠΎΠ², ΡΠΏΠΈΡΠΊΠ° Π»ΠΈΡΠ΅ΡΠ°ΡΡΡΡ.The thesis is devoted to the analysis of the composition and properties of phosphate fertilizers.
When performing this work as a sample of phosphate fertilizers was chosen as monocalcium phosphate. As the main analyzed indicators of quality in work were chosen the following indicators: calcium content, phosphorus content, water content, pH, arsenic. The definition of the selected indicators was carried out by methods recommended by the regulatory documents on investigational products, as well as, physico-chemical analysis methods as methods of comparison. This thesis consists of an introduction, literature review, characteristics of monocalcium phosphate, methods of analysis of monocalcium phosphate, experimental part, discussion of results, references
Hidden Diversity within Tetralophozia filiformis (Marchantiophyta, Anastrophyllaceae) in East Asia
Tetralophozia filiformis s.l. is known from a number of localities mostly in amphi-oceanic areas in Northern Hemisphere, including Atlantic Europe, amphi-Pacific Asia, South Siberia, and western North America. The newly obtained collections of this ‘species’ show strong variation in morphology of the taxon across amphi-Pacific Asia although connected by some ‘intergrading’ modifications. This implies the genetic diversity within this unit earlier recognized as a single taxon. Authors used molecular-genetic, morphological, and chorological methods to understand if the geographically correlated morphological variation also correlates with genetic differences and if it is possible to distinguish some additional taxa within the series of specimens originating from the various areas in amphi-Pacific Asia. It was found that Tetralophozia filiformis is a complex of at least three morphologically similar species, including one long forgotten name (Chandonanthus pusillus) that should be reinstated as separate species and one taxon (Tetralophozia sibirica) that should be described as new. Tetralophozia filiformis and Chandonanthus pusillus are lectotypified, and the new combination is provided for the latter. The three accepted taxa distinctly differ one from another in distribution patterns, preferable climate characteristics, and genetic distances, besides minor differentiations in morphology. The main morphological distinguishing features are the leaf cell size, height of undivided part in leaf lamina, and leaf dentation characteristics. Taking into account the robust correlation between the climate-based and molecular-genetic-based clusters, one more (fourth) taxon could be probably segregated from Tetralophozia filiformis
Pb arachidate Langmuir-Blodgett coatings of silicon wafers: relation between Pb particle density and subphase composition
Recycling Ash and Slag Waste from Thermal Power Plants to Produce Foamed Geopolymers
Ash and slag waste (ASW) from coal combustion creates significant environmental and economic challenges. A promising method of ASW recycling is alkali activation with geopolymer material formation. This study investigates the influence of activating solution components (sodium hydroxide and sodium silicate) on the formation of porous geopolymers using ASW of different origins. The sodium hydroxide content of 0β4 wt.% and the sodium silicate content of 17β25 wt.% were studied. An increase in sodium hydroxide resulted in decreased density, but it adversely affected the strength. An increase in sodium silicate led to a compromised porous structure with relatively high density and compressive strength. An optimal composition, S19N3, comprising 3 wt.% of sodium hydroxide and 19 wt.% of sodium silicate obtained porous geopolymers with uniformly distributed 1.4β2 mm pores and a corresponding density of 335 kg/m3, a compressive strength of 0.55 MPa, a porosity value of 85.6%, and a thermal conductivity value of 0.075 W/(mΒ·K). A mechanism for porous geopolymer formation was developed, including the interaction of alkaline components with ASW and a foaming agent, foaming, curing, and densification. The mechanism was examined using ASW from the Severodvinsk CHPP-1. This study allows for the optimization of geopolymer mixtures with various waste sources and the utilization of waste materials in the construction industry
Improving the Properties of Porous Geopolymers Based on TPP Ash and Slag Waste by Adjusting Their Chemical Composition
The possibility of improving the properties of porous geopolymer materials based on ash and slag waste from thermal power plants by adjusting their chemical composition is considered. An X-ray phase analysis of ash and slag wastes was carried out, the geopolymers’ precursor compositions were calculated, and additives to correct their chemical composition were selected. The samples were synthesized and their physical and mechanical properties (density, porosity, compressive strength, thermal conductivity) were analyzed. The micro- and macro-structure of the samples and the pore distribution of the obtained geopolymers were studied and pore-distribution histograms were obtained. The influence of Si:Al ratio on structural changes was described. The geopolymers’ phase composition was studied, consisting of an amorphous phase and high quartz and mullite. A conclusion about the applicability of this method for obtaining high-quality porous geopolymers was made
Complete and Prolonged Inhibition of Herpes Simplex Virus Type 1 Infection In Vitro by CRISPR/Cas9 and CRISPR/CasX Systems
Almost all people become infected with herpes viruses, including herpes simplex virus type 1 (HSV-1), during their lifetime. Typically, these viruses persist in a latent form that is resistant to all available antiviral medications. Under certain conditions, such as immunosuppression, the latent forms reactivate and cause disease. Moreover, strains of herpesviruses that are drug-resistant have rapidly emerged. Therefore, it is important to develop alternative methods capable of eradicating herpesvirus infections. One promising direction is the development of CRISPR/Cas systems for the therapy of herpesvirus infections. We aimed to design a CRISPR/Cas system for relatively effective long-term and safe control of HSV-1 infection. Here, we show that plasmids encoding the CRISPR/Cas9 system from Streptococcus pyogenes with a single sgRNA targeting the UL30 gene can completely suppress HSV-1 infection of the Vero cell line within 6 days and provide substantial protection within 9 days. For the first time, we show that CRISPR/CasX from Deltaproteobacteria with a single guide RNA against UL30 almost completely suppresses HSV-1 infection of the Vero cell line for 3 days and provides substantial protection for 6 days. We also found that the Cas9 protein without sgRNAs attenuates HSV-1 infection. Our results show that the developed CRISPR/Cas systems are promising therapeutic approaches to control HSV-1 infections
Highways of the emotional intellect: white matter microstructural correlates of an ability-based measure of emotional intelligence
Differentially Expressed Genes and Molecular Susceptibility to Human Age-Related Diseases
Mainstream transcriptome profiling of susceptibility versus resistance to age-related diseases (ARDs) is focused on differentially expressed genes (DEGs) specific to gender, age, and pathogeneses. This approach fits in well with predictive, preventive, personalized, participatory medicine and helps understand how, why, when, and what ARDs one can develop depending on their genetic background. Within this mainstream paradigm, we wanted to find out whether the known ARD-linked DEGs available in PubMed can reveal a molecular marker that will serve the purpose in anyoneβs any tissue at any time. We sequenced the periaqueductal gray (PAG) transcriptome of tame versus aggressive rats, identified rat-behavior-related DEGs, and compared them with their known homologous animal ARD-linked DEGs. This analysis yielded statistically significant correlations between behavior-related and ARD-susceptibility-related fold changes (log2 values) in the expression of these DEG homologs. We found principal components, PC1 and PC2, corresponding to the half-sum and the half-difference of these log2 values, respectively. With the DEGs linked to ARD susceptibility and ARD resistance in humans used as controls, we verified these principal components. This yielded only one statistically significant common molecular marker for ARDs: an excess of FcΞ³ receptor IIb suppressing immune cell hyperactivation