Minimum Information about T Regulatory Cells: A Step toward Reproducibility and Standardization.

Cellular therapies with CD4+ T regulatory cells (Tregs) hold promise of efficacious treatment for the variety of autoimmune and allergic diseases as well as posttransplant complications. Nevertheless, current manufacturing of Tregs as a cellular medicinal product varies between different laboratories, which in turn hampers precise comparisons of the results between the studies performed. While the number of clinical trials testing Tregs is already substantial, it seems to be crucial to provide some standardized characteristics of Treg products in order to minimize the problem. We have previously developed reporting guidelines called minimum information about tolerogenic antigen-presenting cells, which allows the comparison between different preparations of tolerance-inducing antigen-presenting cells. Having this experience, here we describe another minimum information about Tregs (MITREG). It is important to note that MITREG does not dictate how investigators should generate or characterize Tregs, but it does require investigators to report their Treg data in a consistent and transparent manner. We hope this will, therefore, be a useful tool facilitating standardized reporting on the manufacturing of Tregs, either for research purposes or for clinical application. This way MITREG might also be an important step toward more standardized and reproducible testing of the Tregs preparations in clinical applications

Utjecaj predobrade pamuka na bojadisanje prirodnim bojilima

Ovim radom prikazati će se utjecaj predobrada pamučnog materijala na bojadisanje prirodnim bojilima. U radu će biti opisani postupci predobrade pamučnog materijala (iskuhavanje, kemijsko bijeljenje, slobodna mercerizacija i mercerizacija uz rasteg), te dan pregled primjene i svojstava prirodnih bojila. Poseban naglasak bit će stavljen na bojadisanje korama nara i ljuskama luka uz utjecaj različitih močila na dobivena obojenja

Utjecaj predobrade pamuka na bojadisanje prirodnim bojilima

Ovim radom prikazati će se utjecaj predobrada pamučnog materijala na bojadisanje prirodnim bojilima. U radu će biti opisani postupci predobrade pamučnog materijala (iskuhavanje, kemijsko bijeljenje, slobodna mercerizacija i mercerizacija uz rasteg), te dan pregled primjene i svojstava prirodnih bojila. Poseban naglasak bit će stavljen na bojadisanje korama nara i ljuskama luka uz utjecaj različitih močila na dobivena obojenja

Utjecaj predobrade pamuka na bojadisanje prirodnim bojilima

Ovim radom prikazati će se utjecaj predobrada pamučnog materijala na bojadisanje prirodnim bojilima. U radu će biti opisani postupci predobrade pamučnog materijala (iskuhavanje, kemijsko bijeljenje, slobodna mercerizacija i mercerizacija uz rasteg), te dan pregled primjene i svojstava prirodnih bojila. Poseban naglasak bit će stavljen na bojadisanje korama nara i ljuskama luka uz utjecaj različitih močila na dobivena obojenja

Influence of Cotton Pre-Treatment on Dyeing with Onion and Pomegranate Peel Extracts

In this paper the possibility of applying natural dyes on cellulose fibres were researched with respect to the impact of cotton material pre-treatment (scouring, chemical bleaching, mercerization and mordanting), using renewable sources of natural dyes (waste as a source). As mordants, metal salts of copper, aluminium and ferrum were used, and the influence on colour change as well as on fastness properties were analysed. The natural dyes were extracted from onion peel (Allium cepa L.) and pomegranate peel (Punica granatum L.). In spectrophotometric analysis performed of the plant extracts, the onion extract has peaks at 400 and 500 nm, resulting in red-orange colourations and the pomegranate extract shows a maximum at 400 nm, i.e., in the yellow region, which is characteristic of punicalin. Results show significant influence of cotton pre-treatments on colour appearance and fastness properties, caused by pre-treatments affecting the properties and structure of the cotton itself. The positive effect of mercerization on dye absorption and bonding is confirmed. For wash and light fastness properties, more satisfactory results have been obtained for yarns dyed with pomegranate peel natural dye, and the key importance of mordants for fastness properties has been confirmed