886 research outputs found
Family survival against the system
Recent studies show the American family is more resilient to massive societal changes than previously thought
The GEEC2 spectroscopic survey of Galaxy Groups at
We present the data release of the Gemini-South GMOS spectroscopy in the
fields of 11 galaxy groups at , within the COSMOS field. This forms
the basis of the Galaxy Environment Evolution Collaboration 2 (GEEC2) project
to study galaxy evolution in haloes with across cosmic
time. The final sample includes spectroscopically--confirmed members with
per cent complete for galaxies within the virial
radius, and with stellar mass . Including
galaxies with photometric redshifts we have an effective sample size of galaxies within the virial radii of these groups. We present group
velocity dispersions, dynamical and stellar masses. Combining with the GCLASS
sample of more massive clusters at the same redshift we find the total stellar
mass is strongly correlated with the dynamical mass, with
. This stellar
fraction of per cent is lower than predicted by some halo occupation
distribution models, though the weak dependence on halo mass is in good
agreement. Most groups have an easily identifiable most massive galaxy (MMG)
near the centre of the galaxy distribution, and we present the spectroscopic
properties and surface brightness fits to these galaxies. The total stellar
mass distribution in the groups, excluding the MMG, compares well with an NFW
profile with concentration , for galaxies beyond . This is
more concentrated than the number density distribution, demonstrating that
there is some mass segregation.Comment: Accepted for publication in MNRAS. The appendix is omitted due to
large figures. The full version will be available from the MNRAS website and
from http://quixote.uwaterloo.ca/~mbalogh/papers/GEEC2_data.pdf. Long data
tables are available from MNRAS or by contacting the first autho
Bridging the gap -- the disappearance of the intermediate period gap for fully convective stars, uncovered by new ZTF rotation periods
The intermediate period gap, discovered by Kepler, is an observed dearth of
stellar rotation periods in the temperature-period diagram at 20 days
for G dwarfs and up to 30 days for early-M dwarfs. However, because
Kepler mainly targeted solar-like stars, there is a lack of measured periods
for M dwarfs, especially those at the fully convective limit. Therefore it is
unclear if the intermediate period gap exists for mid- to late-M dwarfs. Here,
we present a period catalog containing 40,553 rotation periods (9,535 periods
10 days), measured using the Zwicky Transient Facility (ZTF). To measure
these periods, we developed a simple pipeline that improves directly on the ZTF
archival light curves and reduces the photometric scatter by 26%, on average.
This new catalog spans a range of stellar temperatures that connect samples
from Kepler with MEarth, a ground-based time domain survey of bright M-dwarfs,
and reveals that the intermediate period gap closes at the theoretically
predicted location of the fully convective boundary ( mag). This result supports the hypothesis that the gap is caused by
core-envelope interactions. Using gyro-kinematic ages, we also find a potential
rapid spin-down of stars across this period gap
Gendered nationalism : the gender gap in support for the Scottish National Party
Recent major surveys of the Scottish electorate and of Scottish National Party (SNP) members have revealed a distinct gender gap in support for the party. Men are markedly more likely than women to vote for the SNP and they comprise more than two-thirds of its membership. In this article, we use data from those surveys to test various possible explanations for the disproportionately male support for the SNP. While popular accounts have focused on the gendered appeal of recent leaders and on the party’s fluctuating efforts at achieving gender equality in its parliamentary representation, we find much stronger support for a different explanation. Women are less inclined to support and to join the SNP because they are markedly less supportive of its central objective of independence for Scotland. Since men and women barely differ in their reported national identities, the origins of this gender gap in support for independence presents a puzzle for further research
Clinically driven analysis reveals gene-socioeconomic status interaction influencing periodontal disease in the electronic health record-linked Generation Scotland: Scottish Family Health Study (GS: SFHS) cohort.
Introduction
Heritability (proportion of trait variation attributable to genetic factors) is not a fixed property. It can vary across different social settings and environments. Exploration of gene-environment interaction has been limited by lack of large sample sizes. Biobanks linked to electronic health records pose a solution to this sample size problem.
Objectives and Approach
Social inequalities in periodontal health have been well documented in the dental scientific literature. However, gene-socioeconomic status interaction has yet to be examined. We identified 2,192 cases and 11,525 controls from linked electronic periodontal treatment records within the Generation Scotland: Scottish Family Health Study (GS: SFHS) (www.generationscotland.org). The measure of socioeconomic status used was the Scottish Index of Multiple Deprivation. The objective of this study was to investigate the gene-socioeconomic status interaction within this data. A reaction norm model was used to evaluate the presence of a gene-socioeconomic status interaction in the statistical software ASReml.
Results
We estimated the heritability of periodontal disease at 10.42% (95% confidence interval 5.97-14.88%). Socioeconomic status modified the heritability of periodontal disease. The heritability of was 13.37%, 0.14% and 11.70% in areas of high, moderate and low deprivation respectively; indicating the occurrence of a gene-socioeconomic status interaction with periodontal disease. These results indicate that socioeconomic status explains a large portion of genetic variation in periodontal disease risk. This information suggests that effective intervention and prevention programs for periodontal disease should involve socioeconomic aspects in their planning, implementations and evaluation. For instance, interventions targeted to reduce smoking in more deprived subjects with a genetic predisposition to periodontal disease could enhance the effect of health promotion strategies in reducing risk.
Conclusion/Implications
This study presents contemporary evidence in a large population based cohort that gene-socioeconomic interaction leads to the progression of periodontal disease. This information may lead to the development of better preventative strategies for clinical dentistry
New approaches to the restoration of shallow marginal peatlands
ArticleGlobally, the historic and recent exploitation of peatlands through management practices such as agricultural reclamation, peat harvesting or forestry, have caused extensive damage to these ecosystems. Their value is now increasingly recognised, and restoration and rehabilitation programmes are underway to improve some of the ecosystem services provided by peatlands: blocking drainage ditches in deep peat has been shown to improve the storage of water, decrease carbon losses in the long-term, and improve biodiversity. However, whilst the restoration process has benefitted from experience and technical advice gained from restoration of deep peatlands, shallow peatlands have received less attention in the literature, despite being extensive in both uplands and lowlands. Using the experience gained from the restoration of the shallow peatlands of Exmoor National Park (UK), and two test catchments in particular, this paper provides technical guidance which can be applied to the restoration of other shallow peatlands worldwide. Experience showed that integrating knowledge of the historical environment at the planning stage of restoration was essential, as it enabled the effective mitigation of any threat to archaeological features and sites. The use of bales, commonly employed in other upland ecosystems, was found to be problematic. Instead, ‘leaky dams’ or wood and peat combination dams were used, which are both more efficient at reducing and diverting the flow, and longer lasting than bale dams. Finally, an average restoration cost (£306 ha-1) for Exmoor, below the median national value across the whole of the UK, demonstrates the cost-effectiveness of these techniques. However, local differences in peat depth and ditch characteristics (i.e. length, depth and width) between sites affect both the feasibility and the cost of restoration. Overall, the restoration of shallow peatlands is shown to be technically viable; this paper provides a template for such process over analogous landscapes.South West WaterUniversity of ExeterTechnology Strategy BoardNERCKnowledge Transfer Partnership programm
Thermoregulation of \u3ci\u3eEscherichia coil pap\u3c/i\u3e Transcription: H-NS is a Temperature-Dependent DNA Methylation Blocking Factor
The expression of Pap pili that facilitate the attach- ment of Escherichia coli to uroepithelial cells is shut off outside the host at temperatures below 268C. Ribo- nuclease protection analysis showed that this thermo- regulatory response was rapid as evidenced by the absence of papBA transcripts, coding for Pap pilin, after only one generation of growth at 238C. The his- tone-like nucleoid structuring protein H-NS and DNA sequences within papB were required for thermoregu- lation, but the PapB and PapI regulatory proteins were not. In vivo analysis of pap DNA methylation patterns indicated that H-NS or a factor regulated by H-NS bound within the pap regulatory region at 238C but not at 378C, as evidenced by H-NS-dependent inhibi- tion of methylation of the pap GATC sites designated GATC-I and GATC-II. These GATC sites lie upstream of the papBAp promoter and have been shown pre- viously to play a role in controlling Pap pili expression by regulating the binding of Lrp, a global regulator that is essential for activating papBAp transcription. Competitive electrophoretic mobility shift analysis showed that H-NS bound specifically to a pap DNA fragment containing the GATC-I and GATC-II sites. Moreover, H-NS blocked methylation of these pap GATC sites in vitro : H-NS blocked pap GATC methyla- tion at 1.4 mM but was unable to do so at higher con- centrations at which non-specific binding occurred. Thus, non-specific binding of H-NS to pap DNA was not sufficient to inhibit methylation of the pap GATC sites. These results suggest that the ability of H-NS to act as a methylation blocking factor is dependent upon the formation of a specific complex of H-NS with pap regulatory DNA. We hypothesize that a func- tion of H-NS such as oligomerization was altered at 238C, which enabled H-NS to repress pap gene expres- sion through the formation of a specific nucleoprotein complex
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