医療の意思決定に影響する患者の選好に関する分析 : 2つの実証研究

学位の種別: 課程博士審査委員会委員 : （主査）東京大学教授 康永 秀生, 東京大学教授 小山 博史, 東京大学教授 上別府 圭子, 東京大学准教授 大庭 幸治, 東京大学准教授 豊川 智之University of Tokyo(東京大学

チュウゴク ノ ジュウキンゾク オセン ドジョウ ノ ゲンダイ ト コンゴ ノ タイサク ニ ムケテ ニホン ノ レキシテキ シャテイ カラ エラレタ キョウクン ト サイシン ノ ギジュツ カイハツ ノ テンボウ ヲ フマエテ

大阪大學中國文化論壇 討論文件Discussion Papers in Contemporary China Studies, Osaka University Forum on Chin

Neuralized is expressed in the α/β lobes of adult Drosophila mushroom bodies and facilitates olfactory long-term memory formation

Memory formation involves multiple molecular mechanisms, the nature and components of which are essential to understand these processes. Drosophila is a powerful model to identify genes important for the formation and storage of consolidated memories because the molecular mechanisms and dependence of these processes on particular brain regions appear to be generally conserved. We present evidence that the highly conserved ubiquitin ligase Neuralized (Neur) is expressed in the adult Drosophila mushroom body (MB) α/β lobe peripheral neurons and is a limiting factor for the formation of long-term memory (LTM). We show that loss of one copy of neur gene results in significant LTM impairment, whereas overexpression of Neur in the peripheral neurons of the α/β lobes of the adult MBs results in a dosage-dependent enhancement of LTM. In contrast, learning, early memories, or anesthesia-resistant memory are not affected. We also demonstrate that the role of Neuralized in LTM formation is restricted within the neurons of the periphery of the α/β lobes, and we suggest that this structural subdivision of the MBs participates in the formation of LTM

Variation in Mitochondrial DNA of Vietnamese Pigs: Relationships with Asian Domestic Pigs and Ryukyu Wild Boars

Mitochondrial DNA (mtDNA) sequences (574 bp) of 30 Vietnamese pigs (large and small) were examined and compared with those of 61 haplotypes from wild boars and domestic pigs from various locations in Asia. The large Vietnamese pigs had genetic links to Ryukyu wild boars in southern Japan. The small Vietnamese pigs were closely related to other East Asian domestic pigs. These results indicate that Vietnamese pigs are genetically diverse and may be descendents of wild and domestic pigs from other regions of Asia

Variation in mitochondrial DNA of Vietnamese pigs: Relationships with Asian domestic pigs and Ryukyu wild boars

Mitochondrial DNA (mtDNA) sequences (574 bp) of 30 Vietnamese pigs (large and small) were examined and compared with those of 61 haplotypes from wild boars and domestic pigs from various locations in Asia. The large Vietnamese pigs had genetic links to Ryukyu wild boars in southern Japan. The small Vietnamese pigs were closely related to other East Asian domestic pigs. These results indicate that Vietnamese pigs are genetically diverse and may be descendents of wild and domestic pigs from other regions of Asia