24,779 research outputs found

    Uncovering Ramanujan's "Lost" Notebook: An Oral History

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    Here we weave together interviews conducted by the author with three prominent figures in the world of Ramanujan's mathematics, George Andrews, Bruce Berndt and Ken Ono. The article describes Andrews's discovery of the "lost" notebook, Andrews and Berndt's effort of proving and editing Ramanujan's notes, and recent breakthroughs by Ono and others carrying certain important aspects of the Indian mathematician's work into the future. Also presented are historical details related to Ramanujan and his mathematics, perspectives on the impact of his work in contemporary mathematics, and a number of interesting personal anecdotes from Andrews, Berndt and Ono

    Structural change in the traditional fishery of Kerala and its socio economic implications

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    Motorization of traditional fishing craft has paved the way for a structural change in the artisanal fishery of Kerala. During the mid eighties the traditional sector started operating mini purse seines (Ring seine) and mini trawl nets and consequently the traditional gears in vogue for decades have been either disappeared or thoroughly modified. These two gears together contributed to more than 80% of the traditional landings. Hence the traditional fishing scenario has been completely changed which resulted in far reaching developments in the artisanal fishery sector

    Comment on 'Non-equilibrium thermodynamics of light absorption'

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    A recent paper by Meszéna and Westerhoff (1999 J. Phys. A: Math. Gen. 32 301) has aimed to address what is referred to as a principal question of biological thermodynamics, the possibility of describing photosynthesis in terms of non-equilibrium thermodynamics. The issue is associated with a misrepresentation of the fundamental photophysics involved, and as a result the analysis is invalid

    The economic value of remote sensing by satellite: An ERTS overview and the value of continuity of service. Volume 2: Source document

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    The economic value of an ERS system with a technical capability similar to ERTS, allowing for increased coverage obtained through the use of multiple active satellites in orbit is presented. A detailed breakdown of the benefits achievable from an ERS system is given and a methodology for their estimation is established. The ECON case studies in agriculture, water use, and land cover are described along with the current ERTS system. The cost for a projected ERS system is given

    Regulation of zinc-responsive Slc39a5 (Zip5) translation is mediated by conserved elements in the 3′-untranslated region

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    Translation of the basolateral zinc transporter ZIP5 is repressed during zinc deficiency but Zip5 mRNA remains associated with polysomes and can be rapidly translated when zinc is repleted. Herein, we examined the mechanisms regulating translation of Zip5. The 3′-untranslated region (UTR) of Zip5 mRNA is well conserved among mammals and is predicted by mFOLD to form a very stable stem-loop structure. Three algorithms predict this structure to be flanked by repeated seed sites for miR-328 and miR-193a. RNAse footprinting supports the notion that a stable stem-loop structure exists in this 3′-UTR and electrophoretic mobility shift assays detect polysomal protein(s) binding specifically to the stem-loop structure in the Zip5 3′-UTR. miR-328 and miR-193a are expressed in tissues known to regulate Zip5 mRNA translation in response to zinc availability and both are polysome-associated consistent with Zip5 mRNA localization. Transient transfection assays using native and mutant Zip5 3′-UTRs cloned 3′ to luciferase cDNA revealed that the miRNA seed sites and the stem-loop function together to augment translation of Zip5 mRNA when zinc is replete

    Population Genetic Structuring in Opisthorchis viverrini over Various Spatial Scales in Thailand and Lao PDR

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    Khon Kaen Province in northeast Thailand is known as a hot spot for opisthorchiasis in Southeast Asia. Preliminary allozyme and mitochondrial DNA haplotype data from within one endemic district in this Province (Ban Phai), indicated substantial genetic variability within Opisthorchis viverrini. Here, we used microsatellite DNA analyses to examine the genetic diversity and population structure of O. viverrini from four geographically close localities in Khon Kaen Province. Genotyping based on 12 microsatellite loci yielded a mean number of alleles per locus that ranged from 2.83 to 3.7 with an expected heterozygosity in Hardy-Weinberg equilibrium of 0.44-0.56. Assessment of population structure by pairwise F(ST) analysis showed inter-population differentiation (P<0.05) which indicates population substructuring between these localities. Unique alleles were found in three of four localities with the highest number observed per locality being three. Our results highlight the existence of genetic diversity and population substructuring in O. viverrini over a small spatial scale which is similar to that found at a larger scale. This provides the basis for the investigation of the role of parasite genetic diversity and differentiation in transmission dynamics and control of O. viverrini
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