Determination of trans fatty acid levels by FTIR in processed foods in Australia

Health authorities around the world advise &lsquo;limiting consumption of trans&nbsp;&nbsp; fatty acids&rsquo;, however in Australia the trans fatty acid (TFA) content is not&nbsp; required to be listed in the nutrition information panel unless a declaration or nutrient claim is made about fatty acids or cholesterol. Since there is limited knowledge about trans fatty acid levels in processed foods available in Australia, this study aimed to determine the levels of TFA in selected food items known to be sources of TFA from previously published studies. Food items (n=92) that contain vegetable oil and a total fat content greater than 5% were included. This criterion was used in conjunction with a review of similar studies where food items were found to contain high levels of trans fatty acids. Lipids were extracted using solvents. Gravimetric methods were used to determine total fat content and trans fatty acid levels were quantified by Attenuated Total Reflectance Fourier Transform Infrared spectroscopy. High levels of trans fatty acids were found in certain items in the Australian food supply, with a high degree of variability. Of the samples analysed, 13&nbsp; contained greater than 1 g of trans fatty acids per serving size, the highest value was 8.1 g/serving. Apart from when the nutrition information panel states that the content is less than a designated low level, food labels sold in Australia do not indicate trans fatty acid levels. We suggested that health authorities seek ways to assist consumers to limit their intakes of trans fatty acids.<br /

Comparison of Achilles tendon loading between male and female recreational runners

Recreational running is an activity with multiple reported health benefits for both sexes, however, chronic injuries caused by excessive and/or repetitive loading of the Achilles tendon are common. Males have been identified as being at an increased risk of suffering an injury to the Achilles tendon and as such, knowledge of differences in loading between the sexes may provide further information to better understand why this is the case. The aim of the current investigation was to determine whether gender differences in the Achilles tendon load exist in recreational runners. Fifteen male (age 26.74 ± 5.52 years, body height 1.80 ± 0.11 m and body mass 74.22 ± 7.27 kg) and fifteen female (age 25.13 ± 6.39 years, body height 1.68 ± 0.12 m and body mass 67.12 ± 9.11 kg) recreational runners volunteered to take part in the current investigation. Participants completed 10 trials running at 4.0 m•s-1 ±5% striking a force platform (1000 Hz) with their right foot. Ankle joint kinematics were synchronously recorded (250 Hz) using an optoelectric motion capture system. Ankle joint kinetics were computed using Newton-Euler inverse-dynamics. Net external ankle joint moments were then calculated. To estimate Achilles tendon kinetics the plantarflexion moment calculated was divided by an estimated Achilles tendon moment arm of 0.05 m. Differences in Achilles tendon kinetics were examined using independent sample t-tests (p<0.05). The results indicate that males were associated with significantly (p<0.05) greater Achilles tendon loads than females. The findings from this study support the notion that male recreational runners may be at greater risk of Achilles tendon pathology

Eleven years of sexual discovery

A report on Novartis Foundation Symposium 244 "The Genetics and Biology of Sex Determination", London, UK, 1-3 May 2001

Asymmetric thymocyte death underlies the CD4:CD8 T-cell ratio in the adaptive immune system

It has long been recognized that the T-cell compartment has more CD4 helper than CD8 cytotoxic T cells, and this is most evident looking at T-cell development in the thymus. However, it remains unknown how thymocyte development so favors CD4 lineage development. To identify the basis of this asymmetry, we analyzed development of synchronized cohorts of thymocytes in vivo and estimated rates of thymocyte death and differentiation throughout development, inferring lineage-specific efficiencies of selection. Our analysis suggested that roughly equal numbers of cells of each lineage enter selection and found that, overall, a remarkable ∼75% of cells that start selection fail to complete the process. Importantly it revealed that class I-restricted thymocytes are specifically susceptible to apoptosis at the earliest stage of selection. The importance of differential apoptosis was confirmed by placing thymocytes under apoptotic stress, resulting in preferential death of class I-restricted thymocytes. Thus, asymmetric death during selection is the key determinant of the CD4:CD8 ratio in which T cells are generated by thymopoiesis

Results and Implications: The June "Top-Two" Primary & California's 2012 Legislative Races

This report summarizes some basic results of California’s June 2012 “Top-Two” primary. It focuses on legislative offices with multiple districts within the state: California State Assembly, California State Senate, and United States House of Representatives.James Irvine Foundatio

PREDICTING MUSIC GENRE PREFERENCES BASED ON ONLINE COMMENTS

Communication Accommodation Theory (CAT) states that individuals adapt to each other’s communicative behaviors. This adaptation is called “convergence.” In this work we explore the convergence of writing styles of users of the online music distribution plat- form SoundCloud.com. In order to evaluate our system we created a corpus of over 38,000 comments retrieved from SoundCloud in April 2014. The corpus represents comments from 8 distinct musical genres: Classical, Electronic, Hip Hop, Jazz, Country, Metal, Folk, and World. Our corpus contains: short comments, frequent misspellings, little sentence struc- ture, hashtags, emoticons, and URLs. We adapt techniques used by researchers analyzing other short web-text corpora in order to deal with these problems. We use a supervised machine learning approach to classify the genre of comments in our corpus. We examine the effects of different feature sets and supervised machine learning algorithms on classification accuracy. In total we ran 180 experiments in which we varied: number of genres, feature set composition, and machine learning algorithm. In experiments with all 8 genres we achieve up to 40% accuracy using either a Naive Bayes classifier or C4.5 based classifier with a feature set consisting of 1262 token unigrams and bigrams. This represents a 3 time improvement over chance levels

Influencing health through intestinal microbiota modulation and probiotics

Science has progressed fast in providing answers to probiotic health benefits to the consumers. This symposium also proves that progress is fast. However, several challenges still need to be solved and more effective strains and strain combinations discovered. This will pave the way from good probiotics to specific products for clearly identified target populations. The intestinal microbiota and its interaction(s) with probiotics challenges researchers to turn to the next new page to discover new approaches and treatment modalities that utilize probiotics as means of providing good nutrition with clear health benefits to all consumers.<br /

Solar electron beam transport in the inner heliosphere

Impulsive solar electron beams have an attractive diagnostic potential for poorly understood particle acceleration processes in solar flares. Solar flare accelerated electron beams propagating away from the Sun can interact with the turbulent interplanetary media, producing Langmuir waves and type III radio emission. In this thesis, we simulate electron beam propagation from the Sun to the Earth in the weak turbulent regime taking into account the self-consistent generation of Langmuir waves. We show that an injected single power-law spectrum will be detected at 1 AU as a broken power-law due to wave-particle interaction in the inhomogeneous plasma. We further extend these results by investigating the Langmuir wave interaction with background electron density fluctuations from low frequency MHD turbulence. We find a direct correlation between the spectra of the double power-law below the break energy and the turbulent intensity of the background plasma. Solar flares are believed to accelerate both upward and downward propagating electron beams which can radiate emission at radio and X-ray wavelengths correspondingly. The correlation between X-ray and radio emissions in a well observed solar flare allowed us detailed study of the electron acceleration region properties. We used the Nancay Radioheliograph, Phoenix-2 and RHESSI to infer the type III position, type III starting frequency and spectral index of the HXR emission respectively. Using these datasets and numerical simulations of the electron beam transport in the corona plasma, we were able to infer not only the location (the height in the corona), but to estimate the spatial length of the electron acceleration site

Workshop: Regulatory Gaps in Continuous Processing

1 Objectives To provide a forum for participants to discuss and share experiences relating regulatory approaches and challenges when implementing or considering ICB. Please click Additional Files below to see the full abstract

Weak-value amplification and optimal parameter estimation in the presence of correlated noise

We analytically and numerically investigate the performance of weak-value amplification (WVA) and related parameter estimation methods in the presence of temporally correlated noise. WVA is a special instance of a general measurement strategy that involves sorting data into separate subsets based on the outcome of a second "partitioning" measurement. Using a simplified noise model that can be analyzed exactly together with optimal statistical estimators, we compare WVA to a conventional measurement method. We find that introducing WVA indeed yields a much lower variance of the parameter of interest than does the conventional technique, optimized in the absence of any partitioning measurements. In contrast, a statistically optimal analysis that employs partitioning measurements, incorporating all partitioned results and their known correlations, is found to yield an improvement -- typically slight -- over the noise reduction achieved by WVA. This is because the simple WVA technique is not tailored to a given noise environment and therefore does not make use of correlations between the different partitions. We also compare WVA to traditional background subtraction, a familiar technique where measurement outcomes are partitioned to eliminate unknown offsets or errors in calibration. Surprisingly, in our model background subtraction turns out to be a special case of the optimal partitioning approach in the balanced case, possessing a similar typically slight advantage over WVA. These results give deeper insight into the role of partitioning measurements, with or without post-selection, in enhancing measurement precision, which some have found puzzling. We finish by presenting numerical results to model a more realistic laboratory situation of time-decaying correlations, showing our conclusions hold for a wide range of statistical models.Comment: Revisions incorporate feedback from reviewer