Late Turonian ammonites from Haute-Normandie, France

Upper Turonian chalks of Haute-Normandie yield a distinctive ammonite fauna within the Subprionocyclus neptuni ammonite Zone and the Plesiocorys (Sternotaxis) plana echinoid Zone. Well-localised material all comes from the phosphatic fauna of the Senneville 2 Hardground that marks the boundary between the Formation de Senneville and the Életot Member of the succeeding Formation de Saint-Pierre-en-Port. The association is dominated by Lewesiceras mantelli Wright and Wright, 1951, accompanied by Mesopuzosia mobergi (de Grossouvre, 1894), Lewesiceras woodiWright, 1979, Subprionocyclus hitchinensis (Billinghurst, 1927), Subprionocyclus branneri (Anderson, 1902), Subprionocyclus normalis (Anderson, 1958), Allocrioceras nodiger (F. Roemer, 1870), Allocrioceras billinghursti Klinger, 1976, Hyphantoceras reussianum (d’Orbigny, 1850), Sciponoceras bohemicum bohemicum (Fritsch, 1872), and Scaphites geinitzii d’Orbigny, 1850. The fauna represents the Hyphantoceras reussianum Event of authors, elements of which have been recognised on the north side of Tethys from Northern Ireland to the Mangyschlak Mountains of western Kazakstan, a distance of more than 3,500 kilometres

Trans-Tethyan correlation of the Lower–Middle Cenomanian boundary interval; southern England (Southerham, near Lewes, Sussex) and Douar el Khiana, northeastern Algeria

A 480 m section of marls with widely separated levels of nodular limestone in the Fahdene Formation north of Bou Khadra in Tebessa Province, northeastern Algeria, spans the Lower/Middle Cenomanian boundary. A total of 30 ammonite species are present, of which two: Forbesiceras reversum and Calycoceras (Newboldiceras) algeriense are new. The fauna allows recognition of the Northwest European upper Lower Cenomanian Mantelliceras dixoni Zone, the succeeding lower Middle Cenomanian Cunningtoniceras inerme Zone, the Acanthoceras rhotomagense Zone and its subzones of Turrilites costatus and Turrilites acutus. The sequence of index species occurs in the same order in both north-eastern Tunisia and the Southerham Grey Pit in Sussex (and indeed elsewhere in North-west Europe), indicating these to be robust assemblage zones and subzones that can be recognised on both the north and south sides of the Tethys. Other occurrences of taxa that are common in both sections and regions are markedly different, and include the co-occurrence of Cunningtoniceras inerme (Pervinquière, 1907) with Acanthoceras rhotomagense (Brongniart, 1822) in the costatus Subzone in north-eastern Algeria and central Tunisia, the extension of Acompsoceras renevieri (Sharpe, 1857) into the lower Middle Cenomanian in north-eastern Tunisia, whilst the acme of Turrilites scheuchzerianus Bosc, 1801, is in the dixoni Zone in Northwest Europe, and in the inerme Zone in northeasten Algeria and adjacent parts of Central Tunisia. These differences are not a result of collection failure or non-preservation, but must rather reflect environmental controls on occurrence and abundance

China Maritime Report No. 1: China’s Third Sea Force, The People’s Armed Forces Maritime Militia: Tethered to the PLA

Amid growing awareness that China’s Maritime Militia acts as a Third Sea Force which has been involved in international sea incidents, it is necessary for decision-makers who may face such contingencies to understand the Maritime Militia’s role in China’s armed forces. Chinese-language open sources reveal a tremendous amount about Maritime Militia activities, both in coordination with and independent of the People’s Liberation Army (PLA). Using well-documented evidence from the authors’ extensive open source research, this report seeks to clarify the Maritime Militia’s exact identity, organization, and connection to the PLA as a reserve force that plays a parallel and supporting role to the PLA. Despite being a separate component of China’s People’s Armed Forces (PAF), the militia are organized and commanded directly by the PLA’s local military commands. The militia’s status as a separate non-PLA force whose units act as “helpers of the PLA” (解放军的 助手) is further reflected in China’s practice of carrying out “joint military, law enforcement, and civilian [Navy-Maritime Law Enforcement-Maritime Militia] defense” (军警民联防). To more accurately capture the identity of the Maritime Militia, the authors propose referring to these irregular forces as the “People’s Armed Forces Maritime Militia” (PAFMM).https://digital-commons.usnwc.edu/cmsi-maritime-reports/1000/thumbnail.jp

Digitizing Banking Services: An Empirical Analysis of Customer’s Adoption and Usage

Internet and mobile technologies of recent years have gained momentum and are impacting the working of every process including financial services. Financial service providers including banks are turning their necks toward the wave of these technologies. In the essence it has been made mandatory by situations and conditions in the market that they should be adopted to meet customer demands. This paper will focus on the adoption and perceived usefulness of customers on cyber/Internet banking (IB) and cell phone banking (CB) in India, and the. Data for this study is primary in nature and collected through a survey conducted on 250 respondents across north Indian cities. The result confirms that adoption of IB and CB is on the rise though there is a need for awareness programmes as customers consider it viable. Key words: Cyber banking, Customer, Internet, Cell phone banking, SMS bankin

Followback Clusters, Satellite Audiences, and Bridge Nodes: Coengagement Networks for the 2020 US Election

The 2020 United States presidential election was, and has continued to be, the focus of pervasive and persistent mis- and disinformation spreading through our media ecosystems, including social media. This event has driven the collection and analysis of large, directed social network datasets, but such datasets can resist intuitive understanding. In such large datasets, the overwhelming number of nodes and edges present in typical representations create visual artifacts, such as densely overlapping edges and tightly-packed formations of low-degree nodes, which obscure many features of more practical interest. We apply a method, coengagement transformations, to convert such networks of social data into tractable images. Intuitively, this approach allows for parameterized network visualizations that make shared audiences of engaged viewers salient to viewers. Using the interpretative capabilities of this method, we perform an extensive case study of the 2020 United States presidential election on Twitter, contributing an empirical analysis of coengagement. By creating and contrasting different networks at different parameter sets, we define and characterize several structures in this discourse network, including bridging accounts, satellite audiences, and followback communities. We discuss the importance and implications of these empirical network features in this context. In addition, we release open-source code for creating coengagement networks from Twitter and other structured interaction data.Comment: Accepted for publication at ICWSM '2

The induction of CCN2 by TGFβ1 involves Ets-1

CCN2 is encoded by an immediate-early gene induced in mesenchymal cells during the formation of blood vessels, bone and connective tissue. It plays key roles in cell adhesion and migration, as well as matrix remodeling. CCN2 is overexpressed in fibrosis, arthritis and cancer; thus, an understanding of how to control CCN2 expression is likely to have importance in developing therapies to combat these pathologies. Previously, we found that the promoter sequence GAGGAATG is important for Ccn2 gene regulation in NIH 3T3 fibroblasts. In this report, we show that this sequence mediates activation of the CCN2 promoter by the ETS family of transcription factors. Endogenous Ets-1 binds this element of the CCN2 promoter, and dominant negative Ets-1 and specific Ets-1 small interfering RNA block induction of CCN2 expression by TGFβ. In the absence of added TGFβ1, Ets-1, but not the related fli-1, synergizes with Smad 3 to activate the CCN2 promoter. Whereas the ability of transfected Ets-1 to activate the CCN2 promoter is dependent on protein kinase C (PKC), Ets-1 in the presence of co-transfected Smad3 does not require PKC, suggesting that the presence of Smad3 bypasses the requirement of Ets-1 for PKC to activate target promoter activity. Our results are consistent with the notion that Smad3 and Ets-1 cooperate in the induction of the CCN2 promoter by TGFβ1. Antagonizing Ets-1 might be of benefit in attenuating CCN2 expression in fibrosis, arthritis and cancer, and may be useful in modulating the outcome of these disorders

Primary Corrosion Processes for Polymer-Embedded Free-Standing or Substrate-Supported Silicon Microwire Arrays in Aqueous Alkaline Electrolytes

Solar fuel devices have shown promise as a sustainable source of chemical fuels. However, long-term stability of light absorbing materials remains a substantial barrier to practical devices. Herein, multiple corrosion pathways in 1 M KOH(aq) have been defined for TiO₂-protected Si microwire arrays in a polymer membrane either attached to a substrate or free-standing. Top-down corrosion was observed in both morphologies through defects in the TiO₂ coating. For the substrate-based samples, bottom-up corrosion was observed through the substrate and up the adjacent wires. In the free-standing samples, uniform bottom-up corrosion was observed through the membrane with all wire material corroded within 10 days of immersion in the dark in 1 M KOH(aq)

Nonsurgical treatment for localized hepatocellular carcinoma

The most common non-surgical approaches for the treatment of localized hepatocellular carcinoma remain hepatic artery-delivered particles laden with chemotherapy (TACE), or radioactive microparticles (TARE). External beam radiotherapy has been an effective option in many parts of the world for selected HCC patients, but now has an expanded role with stereotactic and proton beam technologies. This review focuses on existing evidence and current guidance for utilizing these modalities for localized, but unresectable, non-transplantable HCC patients

Reducing in-stent restenosis therapeutic manipulation of miRNA in vascular remodeling and inflammation

Background: Drug-eluting stents reduce the incidence of in-stent restenosis, but they result in delayed arterial healing and are associated with a chronic inflammatory response and hypersensitivity reactions. Identifying novel interventions to enhance wound healing and reduce the inflammatory response may improve long-term clinical outcomes. Micro–ribonucleic acids (miRNAs) are noncoding small ribonucleic acids that play a prominent role in the initiation and resolution of inflammation after vascular injury.<p></p> Objectives: This study sought to identify miRNA regulation and function after implantation of bare-metal and drug-eluting stents.<p></p> Methods: Pig, mouse, and in vitro models were used to investigate the role of miRNA in in-stent restenosis.<p></p> Results: We documented a subset of inflammatory miRNAs activated after stenting in pigs, including the miR-21 stem loop miRNAs. Genetic ablation of the miR-21 stem loop attenuated neointimal formation in mice post-stenting. This occurred via enhanced levels of anti-inflammatory M2 macrophages coupled with an impaired sensitivity of smooth muscle cells to respond to vascular activation.<p></p> Conclusions: MiR-21 plays a prominent role in promoting vascular inflammation and remodeling after stent injury. MiRNA-mediated modulation of the inflammatory response post-stenting may have therapeutic potential to accelerate wound healing and enhance the clinical efficacy of stenting