2,847 research outputs found
Fish Oil Supplementation Reduces Markers of Oxidative Stress But Not Muscle Soreness After Eccentric Exercise
Peer reviewedPostprin
Massive Science with VO and Grids
There is a growing need for massive computational resources for the analysis
of new astronomical datasets. To tackle this problem, we present here our first
steps towards marrying two new and emerging technologies; the Virtual
Observatory (e.g, AstroGrid) and the computational grid (e.g. TeraGrid, COSMOS
etc.). We discuss the construction of VOTechBroker, which is a modular software
tool designed to abstract the tasks of submission and management of a large
number of computational jobs to a distributed computer system. The broker will
also interact with the AstroGrid workflow and MySpace environments. We discuss
our planned usages of the VOTechBroker in computing a huge number of n-point
correlation functions from the SDSS data and massive model-fitting of millions
of CMBfast models to WMAP data. We also discuss other applications including
the determination of the XMM Cluster Survey selection function and the
construction of new WMAP maps.Comment: Invited talk at ADASSXV conference published as ASP Conference
Series, Vol. XXX, 2005 C. Gabriel, C. Arviset, D. Ponz and E. Solano, eds. 9
page
Statistical Computations with AstroGrid and the Grid
We outline our first steps towards marrying two new and emerging
technologies; the Virtual Observatory (e.g, AstroGrid) and the computational
grid. We discuss the construction of VOTechBroker, which is a modular software
tool designed to abstract the tasks of submission and management of a large
number of computational jobs to a distributed computer system. The broker will
also interact with the AstroGrid workflow and MySpace environments. We present
our planned usage of the VOTechBroker in computing a huge number of n-point
correlation functions from the SDSS, as well as fitting over a million CMBfast
models to the WMAP data.Comment: Invited talk to appear in "Proceedings of PHYSTAT05: Statistical
Problems in Particle Physics, Astrophysics and Cosmology
Fast Algorithms and Efficient Statistics: N-point Correlation Functions
We present here a new algorithm for the fast computation of N-point
correlation functions in large astronomical data sets. The algorithm is based
on kdtrees which are decorated with cached sufficient statistics thus allowing
for orders of magnitude speed-ups over the naive non-tree-based implementation
of correlation functions. We further discuss the use of controlled
approximations within the computation which allows for further acceleration. In
summary, our algorithm now makes it possible to compute exact, all-pairs,
measurements of the 2, 3 and 4-point correlation functions for cosmological
data sets like the Sloan Digital Sky Survey (SDSS; York et al. 2000) and the
next generation of Cosmic Microwave Background experiments (see Szapudi et al.
2000).Comment: To appear in Proceedings of MPA/MPE/ESO Conference "Mining the Sky",
July 31 - August 4, 2000, Garching, German
Finding Minimum-Power Broadcast Trees for Wireless Networks
Some algorithms have been devised for use in a method of constructing tree graphs that represent connections among the nodes of a wireless communication network. These algorithms provide for determining the viability of any given candidate connection tree and for generating an initial set of viable trees that can be used in any of a variety of search algorithms (e.g., a genetic algorithm) to find a tree that enables the network to broadcast from a source node to all other nodes while consuming the minimum amount of total power. The method yields solutions better than those of a prior algorithm known as the broadcast incremental power algorithm, albeit at a slightly greater computational cost
Constitutive expression of Yes-associated protein (Yap) in adult skeletal muscle fibres induces muscle atrophy and myopathy
Peer reviewedPublisher PD
Distance dependence of photoinduced long-range electron transfer in zinc/ruthenium-modified myoglobins
An experimental investigation of the distance dependence of long-range electron transfer in zinc/ruthenium-modified myoglobins has been performed. The modified proteins were prepared by substitution of zinc mesoporphyrin IX diacid (ZnP) for the heme in each of four previously characterized pentaammineruthenium(III) (a_5Ru;a = NH_3) derivatives of sperm whale myoglobin (Mb): a_5Ru(His-48)Mb, a_5Ru(His-12)Mb, a_5Ru(His-116)Mb, a_5Ru(His-81)Mb. Electron transfer from the ZnP triplet excited state (^3ZnP*) to Ru^3+, ^3ZnP*-Ru^3+ → ZnP^+-Ru^2+ (ΔE° ~ 0.8V) was measured by time-resolved transient absorption spectroscopy: rate constants (k_f) are 7.0 × 10^4 (His-48), 1.0 × 10^2 (His-12), 8.9 × 10^1 (His-116), and 8.5 × 10^1 (His-81) s^-1 at 25 °C. Activation enthalpies calculated from the temperature dependences of the electron-transfer rates over the range 5-40 °C are 1.7 ± 1.6 (His-48), 4.7 ± 0.9 (His-12), 5.4 ± 0.4 (His-116), and 5.6 ± 2.5 (His-81) kcal mol^-1. Electron-transfer distances (d = closest ZnP edge to a_5Ru(His) edge; angstroms) were calculated to fall in the following ranges: His-48, 11.8-16.6; His-12, 21.5-22.3; His-116, 19.8-20.4; His-81, 18.8-19.3. The rate-distance equation is k_f = 7.8 × 10^8 exp[-0.9l(d - 3)] s^-1 . The data indicate that the ^3ZnP*-Ru(His-12)^3+ electronic coupling may be enhanced by an intervening tryptophan (Trp-14)
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