Paradox of escalation : bidding-fee auctions

In his 1971 study, Dr Martin Shubik, Seymour Knox Professor Emeritus of Mathematical Institutional Economics at Yale University introduces: “an extremely simple, highly amusing, and instructive parlor game which can be played at any party by arranging the auction of a dollar.” Dr. Shubik lectured the Nato Scientific committee in London 1964 about the game. The paradox of escalation auction method teaches a simple escalation, that Dr Shubik compares to military escalations between nations. On a global scale, the inter-nation tensions and escalations have significantly increased in recent times. The escalation is the most visible and loudest between president Trump and the dictator of North Korea. 2017 August - “Tension rises in war of words with US over North Korean threat to fire ballistic missiles near US Pacific territory of Guam”. Dr Shubik's dollar auction game was converted into computerized format in the beginning of the 20th century, however the method was digitized incorrectly and important commonsense auction initiation criteria was overlooked. I have successfully fixed and updated the digital version of the dollar auction game, and I have confirmed my discoveries by interviewing Dr. Shubik on May 16th, 2016. I have applied for patents to my new useful discoveries, and I have already received an Ex Parte Quayle Office Action granted by The United States Patent and Trademark Office, USPTO

Additional file 7: Figure S7. of The evolution of heat shock protein sequences, cis-regulatory elements, and expression profiles in the eusocial Hymenoptera

Percent survival (+/1 SD) of Aphaenogaster picea and P. barbatus (right panel) from heat shock treatments at different temperature treatments. (DOCX 79 kb

Global Phosphoproteomics of Activated B Cells Using Complementary Metal Ion Functionalized Soluble Nanopolymers

Engagement of the B cell receptor for antigen (BCR) leads to immune responses through a cascade of intracellular signaling events. Most studies to date have focused on the BCR and protein tyrosine phosphorylation. Because spleen tyrosine kinase, Syk, is an upstream kinase in multiple BCR-regulated signaling pathways, it also affects many downstream events that are modulated through the phosphorylation of proteins on serine and threonine residues. Here, we report a novel phosphopeptide enrichment strategy and its application to a comprehensive quantitative phosphoproteomics analysis of Syk-dependent downstream signaling events in B cells, focusing on serine and threonine phosphorylation. Using a combination of the Syk inhibitor piceatannol, SILAC quantification, peptide fractionation, and complementary PolyMAC-Ti and PolyMAC-Zr enrichment techniques, we analyzed changes in BCR-stimulated protein phosphorylation that were dependent on the activity of Syk. We identified and quantified over 13 000 unique phosphopeptides, with a large percentage dependent on Syk activity in BCR-stimulated B cells. Our results not only confirmed many known functions of Syk, but more importantly, suggested many novel roles, including in the ubiquitin proteasome pathway, that warrant further exploration

Supplemental Material - Machine learning: Predicting hospital length of stay in patients admitted for lupus flares

Supplemental Material for Machine learning: Predicting hospital length of stay in patients admitted for lupus flares by Radu Grovu, Yanran Huo, Andrew Nguyen, Omar Mourad, Zihang Pan, Khalil El-Gharib, Chapman Wei, Ahmad Mustafa, Theodore Quan and Anastasia Slobodnick in Lupus.</p

Additional file 4: of Thermal reactionomes reveal divergent responses to thermal extremes in warm and cool-climate ant species

Technical Report containing full details of the analysis. (PDF 970 kb

Postgrowth Tuning of the Bandgap of Single-Layer Molybdenum Disulfide Films by Sulfur/Selenium Exchange

We demonstrate bandgap tuning of a single-layer MoS₂ film on SiO₂/Si <i>via</i> substitution of its sulfur atoms by selenium through a process of gentle sputtering, exposure to a selenium precursor, and annealing. We characterize the substitution process both for S/S and S/Se replacement. Photoluminescence and, in the latter case, X-ray photoelectron spectroscopy provide direct evidence of optical band gap shift and selenium incorporation, respectively. We discuss our experimental observations, including the limit of the achievable bandgap shift, in terms of the role of stress in the film as elucidated by computational studies, based on density functional theory. The resultant films are stable in vacuum, but deteriorate under optical excitation in air