The Necessity of the Wooing of Anne in \u3cem\u3eRichard III\u3c/em\u3e

Richard\u27s wooing of Anne has strained the credibility of modern audiences and readers to an extent unparalleled by any other scene in Shakespeare. Much critical attention has focused on attempts to defend the realism of the scene. Denzell S. Smith, for example, shows how Richard changes his pose to accord with the natural progression of Anne\u27s emotions, from forceful prince, to pleader, to innocent, to brazen lover and so on as he anticipates Anne\u27s reactions and meets them with a response that is psychologically (and dramatically) convincing. Anne\u27s reaction to Richard is that of a defenseless small animal to a cobra: he hypnotizes her with his rhetorical motions, and refuses to release her until she yields. Anne\u27s capitulation can be explained nicely in terms acceptable to modern students of human behavior

Game Volatility At Baccarat

The authors discuss the volatility of table games using Baccarat as an example. The expected deviation from the win, in percentage terms, will decrease as the number of decisions is increased. In absolute terms, the deviation is likely to increase as decisions increase. Through the formulas presented in the article the author shows there is no natural evening-up process. That is if a casino lost one million dollars on Baccarat play last month, the casino manager cannot expect to make the theoretical win plus an additional one million next month. The article will help managers understand and plan for fluctuations in table game play

THE CONSEQUENCE OF ODDD HYPOMYELINATION-LINKED Cx43 MUTATIONS ON HETEROTYPIC GAP JUNCTIONAL INTERCELLULAR COMMUNICATION BETWEEN Cx43/Cx47 GAP JUNCTION CHANNELS

Gap junction (GJ) channels, a conduit for intercellular communication between adjacent cells, are composed of connexins (Cxs). Human macroglial cells express non-overlapping Cxs with oligodendrocytes expressing Cx47, Cx32 and Cx29 while astrocytes express Cx43, Cx30 and Cx26. Intercellular communication between oligodendrocytes and astrocytes depends on heterotypic GJ channels, predominantly Cx47/Cx43 heterotypic channels. Mutations in either Cx47 or Cx43 have been linked to central hypomyelination diseases, suggesting a critical role of Cx47/Cx43 GJ channels. Moreover, patients with Cx43 mutations exhibit pleiotropic phenotypes with only some mutations linking to central hypomyelination. Our aim is to study functional changes of hypomyelination-linked Cx43 mutants K134N, G138R, and V96A against non- hypomyelination-linked Cx43 mutants R76H, H194P, and V96M. We found that all mutants were functionally impaired in either homotypic or heterotypic GJ channel formation with Cx47, suggesting that electrical coupling via the heterotypic Cx43/Cx47 GJ channels may not be critical in the maintenance of central myelination

Water Diffusion Rates Through Serpentinized Peridotites: Implications For Reaction Induced Dynamic And Chemical Effects In Ultramafic Rocks

A typical serpentinization reaction is of the type: Mg(,2)SiO(,4) + MgSiO(,3) + 2H(,2)O (---\u3e) Mg(,3)Si(,4)O(,5)(OH)(,4), involving a 40% volume expansion and considerable heat generation. At all temperatures between 100(DEGREES)C and 400(DEGREES)C rates of serpentinization are geologically rapid and are controlled by the rate at which water is supplied to the reaction interface. Once serpentine begins to form, any further reaction will depend on the rate of water penetration through an existing layer of serpentine. Defects 100-1000 A wide produced by the buckling of the platy serpentine mineral, lizardite, provide the permeability.;An experimental study, at room temperatures (25(DEGREES)C-40(DEGREES)C), has shown that a thin (3-4 mm) slice of serpentinized periodotite placed in a diffusion cell exhibits a significant permeability to water, while behaving semipermeably to salt. Diffusion coefficients of water at 34(DEGREES)C range from 10(\u27-7) to 10(\u27-8) cm(\u272) sec(\u27-1), whereas using a modified Darcy equation intrinsic permeability coefficients of 10(\u27-11) to 10(\u27-12) darcys are obtained.;At a typical serpentinization temperature of 200(DEGREES)C D(,H(,2)O) is estimated to be on the order of 10(\u27-5) cm(\u272) sec(\u27-1). Using the parabolic rate law, x = (2Dt)(\u27 1/2), such coefficients imply a mean penetration distance, x, through serpentinized peridotites in the range of 1-80 cm a(\u27-1). It thus appears that in deep (i.e. \u3e 5 km) groundwater or marine environments, water will penetrate massive serpentinite at an appreciable rate and hence will lead to moderately rapid reaction rates. Given the large P(,H(,2)O) gradient produced by the reaction (i.e. P(,H(,2)O) external - P(,H(,2)O) reaction interface), the process will cause large volume strains coupled to flow and reaction rates.;As the swelling pressure (stresses) of the reaction are on the order of 1 kb, refracturing will be a continuous process. Microstructures, ubiquitous to all serpentinized peridotites, show that microfracturing has occurred on all scales and is in accord with high local volume strains. In such environments serpentinization should be a continuous process, controlled only by water access to ultramafic rocks through their cover

Applying Probabilistic Methods to the NATO Military Load Classification System for Bridges

Military vehicles frequently use civilian bridges. The loading effects of military vehicles, both wheeled and tracked, are specific and different than those of civilian vehicles in normal traffic. Calibration to determine appropriate load factors for military loading of civilian bridges has not been fully performed and the corresponding levels of safety have not been quantified. This lack of calibration prevents the implementation of limit state design methods for military bridges and the evaluation bridges for military loading. This thesis quantifies probabilistically the single lane traffic load effects on interior girders of simply supported slab-on-girder bridges for three military vehicles in use by the Canadian Forces with corresponding load factors for design and evaluation. General categories of military vehicles are proposed with associated partial load factors for application in military bridge design and evaluation. Keywords: Bridge evaluation, Military vehicle, Live load, Load factors, Limit state design, Code calibration, Military engineering, Bridges, Simply-Supported Spans, Slab-on-Girde