Memantine for prevention of migraine: a retrospective study of 60 cases.

The objective was to retrospectively characterise the efficacy of memantine as preventive therapy in a series of patients with frequent migraine. Patients in a university headache clinic completed a survey regarding their experience with memantine, and medical records were reviewed. All patients who received memantine as preventive therapy for migraine over a 15-month period were mailed surveys and consent forms for record review. Patients were treated with memantine beginning at a dose of 5 mg/day, increasing if needed by 5 mg/week up to 10 mg twice a day. The majority of patients (36 out of 54) treated with memantine for at least 2 months reported a significant reduction in estimated headache frequency, and improved function. Side effects were uncommon and generally mild. This limited retrospective case review suggests that memantine may be an effective preventive therapy for patients with frequent migraine. A prospective trial is warranted

Social security measures in Great Britain and the United States

Thesis (M.B.A.)--Boston University, 1936. This item was digitized by the Internet Archive

Determining and testing the optimal pure-tone frequency for use in acoustic conditioning of free-ranging common carp (Cyprinus carpio)

Pure-tone frequencies of 400, 700, and 1000 Hz were tested to determine which achieved the strongest response when used in conditioning experiments on captive common carp (Cyprinus carpio) for the purpose of determining the most effective frequency to use in conditioning experiments on free-ranging common carp. Captive common carp were shown to have the strongest response to the 400 Hz frequency after training that associated sound with food. Response was quantified as moving into a feeding arena when the sound was broadcast, and all frequencies achieved conditioning within five days. Secondly, the attenuation of the three frequencies were compared in a Waikato lake (Lake Kaituna) containing common carp. The ability to maintain signal strength over distance is necessary for frequencies used in the acoustic conditioning of free-ranging common carp due to the potentially large distances involved. Attenuation of the 400 Hz and 700 Hz pure tone frequencies were not significantly different but were both lower than that of the 1000 Hz frequency. The 400 Hz pure tone frequency was used in subsequent experiments on the acoustic conditioning of free-ranging common carp in Lake Kaituna because of superior performance in acoustic conditioning of captive common carp and low attenuation in a natural water body containing free-ranging common carp,. Thirdly, the 400 Hz pure tone was evaluated for its ability to be associated with food by free-ranging common carp. Capture rates at treatment sites where 400 Hz pure tone was broadcast compared to control sites where no sound was broadcast following a five-day training phase and 24 h of no sound or food, were 2.1 times greater during a three-day capture phase. This study demonstrates the trainability of common carp, a trait that can be used to improve control of wild common carp populations