Staging and resilience degree in breast cancer survivors

Objective: To assess the resilience and staging degree relating to sociodemographic factors of breast cancer survivors followed up in an oncology service. Method: Quantitative study with 112 breast cancer survivors. The variables selected were: sociodemographic; clinical staging; survival time; and resilience scale. The analysis was performed using the Epi Info 6.04 software and Fisher's exact test. The research was approved by the Ethics Committee of the Federal University of Pelotas School of Nursing under Opinion Nº 31/2009. Results: The average age was 46,2 years, there was 60,71% of stage II cases, 81,25% were white, 40,18% had five-to eight-year schooling, 52,68% were married, 73,32% had lived in urban areas, 41,96% exhibited high resilience, and 48,21% were followed up from one to three years. Conclusion: Staging was not associated with the resilience degree, but rather with age and survival time, confirming the findings of other studies

Staging and resilience degree in breast cancer survivors

Objective: To assess the resilience and staging degree relating to sociodemographic factors of breast cancer survivors followed up in an oncology service. Method: Quantitative study with 112 breast cancer survivors. The variables selected were: sociodemographic; clinical staging; survival time; and resilience scale. The analysis was performed using the Epi Info 6.04 software and Fisher's exact test. The research was approved by the Ethics Committee of the Federal University of Pelotas School of Nursing under Opinion Nº 31/2009. Results: The average age was 46,2 years, there was 60,71% of stage II cases, 81,25% were white, 40,18% had five-to eight-year schooling, 52,68% were married, 73,32% had lived in urban areas, 41,96% exhibited high resilience, and 48,21% were followed up from one to three years. Conclusion: Staging was not associated with the resilience degree, but rather with age and survival time, confirming the findings of other studies

Perspectiva dos trabalhadores da Estratégia de Saúde da Família na promoção da saúde ao idoso rural

Objective: to unveil the perspective of health promotion of family health strategy workers in relation to rural elderly. Method: qualitative, participant action type, with 25 health professionals, listed for convenience in a municipality in southern Brazil. The collection period took place from August to December 2019. Data analysis through Paulo Freire's Culture Circles. Five crop circles were held, with an average duration of one hour, all recorded and photographed. Results: from the data obtained after the dynamics with the participants, five themes emerged: Adoption of healthy habits; The family as a health promoter; Disease prevention; Collective Activity; and the worker as a health promoter. Conclusion: health promotion from the perspective of strategy workers has its bases in the pillar of behavioral change in individual lifestyle and quality of life.Objetivo: conocer la perspectiva de promoción de la salud de los trabajadores de la estrategia de salud de la familia en relación con los ancianos rurales. Método: cualitativo, tipo de acción participante, con 25 profesionales de la salud, listados por conveniencia en un municipio del sur de Brasil. El período de recolección tuvo lugar de agosto a diciembre de 2019. Análisis de datos a través de los Círculos culturales de Paulo Freire. Se realizaron cinco círculos de las cosechas, con una duración promedio de una hora, todos grabados y fotografiados. Resultados: de los datos obtenidos tras la dinámica con los participantes, surgieron cinco temas: Adopción de hábitos saludables; La familia como promotora de salud; Prevención de enfermedades; Actividad Colectiva; y el trabajador como promotor de salud. Conclusión: la promoción de la salud desde la perspectiva de los trabajadores de estrategia tiene sus bases en el pilar del cambio de comportamiento en el estilo de vida individual y la calidad de vida.Objetivo: desvelar a perspectiva de promoção da saúde dos trabalhadores de Estratégia de Saúde da Família em relação aos idosos rurais. Método: qualitativo, tipo ação participante, com 25 profissionais da saúde, elencados por conveniência em um município da região sul do Brasil. O período de coleta ocorreu de agosto a dezembro de 2019. Análise dos dados por meio dos Círculos de Cultura de Paulo Freire. Foram realizados cinco círculos de cultura, com duração média de uma hora, todos gravados e fotografados. Resultados:  a partir dos dados obtidos após a realização da dinâmica com os participantes, emergiram cinco temas: Adoção de hábitos saudáveis; A família como promotora de saúde; Prevenção de doenças; Atividade Coletiva; e O trabalhador como promotor de saúde. Conclusão: a promoção da saúde na perspectiva dos trabalhadores da estratégia tem suas bases no pilar de mudança comportamental de estilo e qualidade de vida individual

Perfil dos idosos de uma instituição de longa permanência

Objetivo: descrever o perfil dos idosos de uma Instituição de Longa Permanência. Métodos: trata-se de uma pesquisa quantitativa, descritiva transversal, desenvolvida entre março/maio de 2010 em uma ILPI. Os dados foram coletados em abril de 2010 utilizando questionário estruturado com questões sobre o perfil do idoso, doenças preexistentes e o nível de independência (KATZ), e para análise foram digitados duplamente no Epinfo. Resultados: obteve-se que a maioria dos idosos eram mulheres, longevas, brancas, viúvas e alfabetizadas. As doenças mais prevalentes foram problemas cardíacos e Diabetes Melittus. Quanto a escala de Katz 45% obteve escore 1.Conclusão:assim, muitos idosos mantiveram a independência funcional, confirmando a necessidade do uso de um instrumento de avaliação para promoção da saúde, sendo a Escala de Katz de fácil aplicação para avaliar as limitações das atividades diária

Estadiamento e grau de resiliência do sobrevivente ao câncer de mama Staging and resilience degree in breast cancer survivors

Objetivo: Investigar o grau de resiliência e de estadiamento frente aos fatores sociodemográficos dos sobreviventes ao câncer de mama em acompanhamento em um serviço de oncologia. Métodos: Estudo quantitativo, amostra de 112 sobreviventes ao câncer de mama. Foram selecionadas variáveis sociodemográficas, estadiamento clínico, tempo de sobrevida e escala de resiliência. Análise no epi-info 6.04 e teste exato de fischer. Aprovação do Comitê de Ética da Faculdade de Enfermagem da UFPel  nº 31/2009. Resultados: média de idade de 46,2 anos, 60,71% estadiamento II, 81,25% eram brancas, 40,18% com escolaridade entre 5-8 anos, 52,68% casados, 73,32% viveu em zona urbana, 41,96% apresentou alta resiliência e 48,21% mantinha-se em acompanhamento entre 1-3 anos. Conclusão: O estadiamento não está associado ao grau de resiliência, mas sim à idade e tempo de sobrevida confirmando os achados em outros estudos

Estadiamento e grau de resiliência do sobrevivente ao câncer de mama Staging and resilience degree in breast cancer survivors

Objetivo: Investigar o grau de resiliência e de estadiamento frente aos fatores sociodemográficos dos sobreviventes ao câncer de mama em acompanhamento em um serviço de oncologia. Métodos: Estudo quantitativo, amostra de 112 sobreviventes ao câncer de mama. Foram selecionadas variáveis sociodemográficas, estadiamento clínico, tempo de sobrevida e escala de resiliência. Análise no epi-info 6.04 e teste exato de fischer. Aprovação do Comitê de Ética da Faculdade de Enfermagem da UFPel  nº 31/2009. Resultados: média de idade de 46,2 anos, 60,71% estadiamento II, 81,25% eram brancas, 40,18% com escolaridade entre 5-8 anos, 52,68% casados, 73,32% viveu em zona urbana, 41,96% apresentou alta resiliência e 48,21% mantinha-se em acompanhamento entre 1-3 anos. Conclusão: O estadiamento não está associado ao grau de resiliência, mas sim à idade e tempo de sobrevida confirmando os achados em outros estudos

Telomere length and epigenetic age acceleration in adolescents with anxiety disorders

Evidence on the relationship between genetics and mental health are flourishing. However, few studies are evaluating early biomarkers that might link genes, environment, and psychopathology. We aimed to study telomere length (TL) and epigenetic age acceleration (AA) in a cohort of adolescents with and without anxiety disorders (N = 234). We evaluated a representative subsample of participants at baseline and after 5 years (n = 76) and categorized them according to their anxiety disorder diagnosis at both time points: (1) control group (no anxiety disorder, n = 18), (2) variable group (anxiety disorder in one evaluation, n = 38), and (3) persistent group (anxiety disorder at both time points, n = 20). We assessed relative mean TL by real-time quantitative PCR and DNA methylation by Infinium HumanMethylation450 BeadChip. We calculated AA using the Horvath age estimation algorithm and analyzed differences among groups using generalized linear mixed models. The persistent group of anxiety disorder did not change TL over time (p = 0.495). The variable group had higher baseline TL (p = 0.003) but no accelerated TL erosion in comparison to the non-anxiety control group (p = 0.053). Furthermore, there were no differences in AA among groups over time. Our findings suggest that adolescents with chronic anxiety did not change telomere length over time, which could be related to a delay in neuronal development in this period of life

Experiencia de investigación desarrollada con ancianos residentes en la zona rural

Objective: to report the development of a research with elderly people who live in the countryside. Methods: it is a reflection on the lived experiences during the execution of a research performed with an elderly population developed in the countryside of Pelotas (RS), from 2013 to 2014. Results: it presents how a research with 820 elderly people in the countryside was performed, its logistic and importance in all stages of the study. Besides demonstrating that from this Research Project, subthemes of work were developed as frailty elderly syndrome, tumbles, functional capacity, chronic disease, cancer, depression, among others. Final Considerations: it is highlighted the importance of planning and executing scheduling of a quantitative research, especially the logistic of data collection in order to have a successful research

Relative frequency and estimated minimal frequency of Lysosomal Storage Diseases in Brazil: Report from a Reference Laboratory

Abstract Lysosomal storage diseases (LSDs) comprise a heterogeneous group of more than 50 genetic conditions of inborn errors of metabolism (IEM) caused by a defect in lysosomal function. Although there are screening tests for some of these conditions, diagnosis usually depends on specific enzyme assays, which are only available in a few laboratories around the world. A pioneer facility for the diagnosis of IEM and LSDs was established in the South of Brazil in 1982 and has served as a reference service since then. Over the past 34 years, samples from 72,797 patients were referred for investigation of IEM, and 3,211 were confirmed as having an LSD (4.41%, or 1 in 22), with 3,099 of these patients originating from Brazil. The rate of diagnosis has increased over time, in part due to the creation of diagnostic networks involving a large number of Brazilian services. These cases, referred from Brazilian regions, provide insight about the relative frequency of LSDs in the country. The large amount of data available allows for the estimation of the minimal frequency of specific LSDs in Brazil. The reported data could help to plan health care policies, as there are specific therapies available for most of the cases diagnosed