3,118 research outputs found
Gravitational waves from three-dimensional core-collapse supernova models: The impact of moderate progenitor rotation
We present predictions for the gravitational-wave (GW) emission of
three-dimensional supernova (SN) simulations performed for a 15 solar-mass
progenitor with the Prometheus-Vertex code using energy-dependent, three-flavor
neutrino transport. The progenitor adopted from stellar evolution calculations
including magnetic fields had a fairly low specific angular momentum (j_Fe <~
10^{15} cm^2/s) in the iron core (central angular velocity ~0.2 rad/s), which
we compared to simulations without rotation and with artificially enhanced
rotation (j_Fe <~ 2*10^{16} cm^2/s; central angular velocity ~0.5 rad/s). Our
results confirm that the time-domain GW signals of SNe are stochastic, but
possess deterministic components with characteristic patterns at low
frequencies (<~200 Hz), caused by mass motions due to the standing accretion
shock instability (SASI), and at high frequencies, associated with gravity-mode
oscillations in the surface layer of the proto-neutron star (PNS). Non-radial
mass motions in the post-shock layer as well as PNS convection are important
triggers of GW emission, whose amplitude scales with the power of the
hydrodynamic flows. There is no monotonic increase of the GW amplitude with
rotation, but a clear correlation with the strength of SASI activity. Our
slowly rotating model is a fainter GW emitter than the non-rotating model
because of weaker SASI activity and damped convection in the post-shock layer
and PNS. In contrast, the faster rotating model exhibits a powerful SASI spiral
mode during its transition to explosion, producing the highest GW amplitudes
with a distinctive drift of the low-frequency emission peak from ~80-100 Hz to
~40-50 Hz. This migration signifies shock expansion, whereas non-exploding
models are discriminated by the opposite trend.Comment: Added new figure, figure 9. Updated figure 9, now figure 10. Modified
the discussion of the proto-neutron star convection. Added a figure showing
the average rotation rate as a function of radius. Added a section discussing
where the low-frequency gravitational waves are generated, this information
is visualized in figure 9. We also made some minor changes to the text and
selected plot
Gravitational-wave signals from 3D supernova simulations with different neutrino-transport methods
We compare gravitational-wave (GW) signals from eight three-dimensional simulations of core-collapse supernovae from Glas et al. (2019), using two different progenitors with zero-age main sequence masses of 9 and 20 solar masses. The collapse of each progenitor was simulated four times, at two different grid resolutions and with two different neutrino transport methods, using the Aenus-Alcar code. The main goal of this study is to assess the validity of recent concerns that the so-called "Ray-by-Ray+" (RbR+) approximation is problematic in core-collapse simulations and can adversely affect theoretical GW predictions. Therefore, signals from simulations using RbR+ are compared to signals from corresponding simulations using a fully multidimensional (FMD) transport scheme. The 9 solar-mass progenitor successfully explodes, whereas the 20 solar-mass model does not. Both the standing accretion shock instability and hot-bubble convection develop in the postshock layer of the non-exploding models. In the exploding models, neutrino-driven convection in the postshock flow is established around 100 ms after core bounce and lasts until the onset of shock revival. We can, therefore, judge the impact of the numerical resolution and neutrino transport under all conditions typically seen in non-rotating core-collapse simulations. We find excellent qualitative agreement in all GW features and mostly very satisfactory quantitative agreement between simulations using the different transport schemes. Overall, resolution-dependent differences in the hydrodynamic behaviour of low-resolution and high-resolution models turn out to have a greater impact on the GW signals than consequences of the different transport methods. Furthermore, increasing the resolution decreases the discrepancies between models with different neutrino transport
Substrate stiffness and VE-cadherin mechano-transduction coordinate to regulate endothelial monolayer integrity.
The vascular endothelium is subject to diverse mechanical cues that regulate vascular endothelial barrier function. In addition to rigidity sensing through integrin adhesions, mechanical perturbations such as changes in fluid shear stress can also activate force transduction signals at intercellular junctions. This study investigated how extracellular matrix rigidity and intercellular force transduction, activated by vascular endothelial cadherin, coordinate to regulate the integrity of endothelial monolayers. Studies used complementary mechanical measurements of endothelial monolayers grown on patterned substrates of variable stiffness. Specifically perturbing VE-cadherin receptors activated intercellular force transduction signals that increased integrin-dependent cell contractility and disrupted cell-cell and cell-matrix adhesions. Further investigations of the impact of substrate rigidity on force transduction signaling demonstrated how cells integrate extracellular mechanics cues and intercellular force transduction signals, to regulate endothelial integrity and global tissue mechanics. VE-cadherin specific signaling increased focal adhesion remodeling and cell contractility, while sustaining the overall mechanical equilibrium at the mesoscale. Conversely, increased substrate rigidity exacerbates the disruptive effects of intercellular force transduction signals, by increasing heterogeneity in monolayer stress distributions. The results provide new insights into how substrate stiffness and intercellular force transduction coordinate to regulate endothelial monolayer integrity
The negative acute phase response of serum transthyretin following Streptococcus suis infection in the pig
Peer reviewedPublisher PD
Estimation of Density-Dependent Mortality of Juvenile Bivalves in the Wadden Sea
We investigated density-dependent mortality within the early months of life of the bivalves Macoma balthica (Baltic tellin) and Cerastoderma edule (common cockle) in the Wadden Sea. Mortality is thought to be density-dependent in juvenile bivalves, because there is no proportional relationship between the size of the reproductive adult stocks and the numbers of recruits for both species. It is not known however, when exactly density dependence in the pre-recruitment phase occurs and how prevalent it is. The magnitude of recruitment determines year class strength in bivalves. Thus, understanding pre-recruit mortality will improve the understanding of population dynamics. We analyzed count data from three years of temporal sampling during the first months after bivalve settlement at ten transects in the Sylt-Rømø-Bay in the northern German Wadden Sea. Analyses of density dependence are sensitive to bias through measurement error. Measurement error was estimated by bootstrapping, and residual deviances were adjusted by adding process error. With simulations the effect of these two types of error on the estimate of the density-dependent mortality coefficient was investigated. In three out of eight time intervals density dependence was detected for M. balthica, and in zero out of six time intervals for C. edule. Biological or environmental stochastic processes dominated over density dependence at the investigated scale
Focusing Capillary Optics for Use in Solution Small-Angle X-Ray Scattering
Measurements of the global conformation of macromolecules can be carried out using small-angle X-ray scattering (SAXS). Glass focusing capillaries, manufactured at the Cornell High Energy Synchrotron Source (CHESS), have been successfully employed for SAXS measurements on the heme protein cytochrome c. These capillaries provide high X-ray flux into a spot size of tens of micrometres, permitting short exposures of small-volume samples. Such a capability is ideal for use in conjunction with microfluidic mixers, where time resolution may be determined by beam size and sample volumes are kept small to facilitate mixing and conserve material
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