5,554 research outputs found

    Trust is bound to emerge (In the repeated Trust Game)

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    This paper addresses the emergence of cooperation in asymmetric pris- oners' dilemmas in which one player chooses after having observed the other player's choice (Trust Game). We use the finite automata approach with complexity costs to study the equilibria of the repeated version of this game. We show that there is a small set of automata that form the unique Closed Under Rational Behavior (CURB) set for this game. This set contains two non-strict Nash equilibria, a cooperative and a non- cooperative one. We show that the cooperative equilibrium is the only (cyclically) stable set under the so called Best Response Dynamics.

    Inspection games with long-run inspectors

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    A single, long-run policeman faces a large population of myopic would- be criminals. This paper shows that this interaction has counterintuitive comparative static properties. A forward-looking inspector might tolerate more law violations than a short-sighted one.

    An importance sampling algorithm for generating exact eigenstates of the nuclear Hamiltonian

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    We endow a recently devised algorithm for generating exact eigensolutions of large matrices with an importance sampling, which is in control of the extent and accuracy of the truncation of their dimensions. We made several tests on typical nuclei using a correlated basis obtained from partitioning the shell model space. The sampling so implemented allows not only for a substantial reduction of the shell model space but also for an extrapolation to exact eigenvalues and E2 strengths.Comment: A compressed file composed of a text in latex of 19 pages and 9 figures in p

    EGI: anOpen e-Infrastructure Ecosystem for the Digital European Research Area

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    Bringing the digital European Research Area (ERA) online means modernising Europe’s research infrastructure by promoting open science through the availability, accessibility and reuse of scientific data and results, the use of web- based tools that facilitate scientific collaboration and ensuring public access to research. As the European Grid Infrastructure (EGI) is the largest European distributed computing infrastructure providing 24/7 access to large scale computing, storage and data resources through a federation of national resource providers, it allows scientists from all disciplines to make the most out of the latest computing technologies for the benefit of their research. This paper describes the methodology and approach for defining EGI’s role in bringing this digital ERA online. The work presented defines the roles and functions of EGI as an open ICT ecosystem, required service redesign, the added value of EGI for the European research communities and demonstrates the role that EGI plays in contributing to the Europe 2020 strategy for social-economic impact

    Immaginare il porto/immaginare Trieste. Strategie portuali, geografie dei traffici e saturazione del territorio e dello spazio ecologico

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    The paper proposes an analysis of some traditional ideas of the historical research about the port of Trieste, as for instance the role of Habsburg monarchy in the development of the port and of the town, and the turning-point of First World War. The importance of examining such concepts its great, because they are still used in the elaboration of development strategies for the city.Si propone una analisi di alcuni concetti tradizionali della ricerca storica sul porto di Trieste, come il ruolo della monarchia absburgica nello sviluppo del porto e della città e la svolta rappresentata dalla Prima guerra mondiale. È importante esaminare tali concetti, poiché essi sono tuttora impiegati nell’elaborazione di strategie di sviluppo della città

    Frantumi. Cittadinanze, diritti e spazi dall’Antico regime alla crisi globale

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    Prima dell'affermazione della cittadinanza europea creata dagli eventi della Rivoluzione Francese e della sua narrazione intrecciatasi alla supremazia delle nazioni e ai confini e alle omogeneità fordiste, la cittadinanza si è presentata differenziata, scindibile e plurima e spesso è stata affiancata da altri modelli di relazioni territorio/diritti e di accesso alle relazioni materiali e immateriali, quali la residenza e la nascita. Questo, inoltre, è avvenuto in quadro di relazioni dense e fluide tra le comunità cittadine e le istanze istituzionali ad esse superiori. Costruita in tal modo, la cittadinanza 'europea' viene sottoposta a enormi tensioni dalla crisi delle nazioni, dallo sviluppo delle nuove forme dell'economia globale e dalle crisi/ristrutturazioni che lo accompagnano. La cittadinanza, così, muta e perde le sue capacità di organizzazione e le sue caratteristiche di unicità. Si frantuma in diritti scomponibili e assume fluidità di funzioni e utilizzi presentandosi da un lato come meno capace di difendere diritti, dall'altro come possibile elemento di strategie individuali complesse. Inoltre, nel gioco stato, città e entità sovrastatali, muta nuovamente ruolo e posizione.. Nel frattempo le prossimità, omogeneità, gerarchie e somiglianze prima richieste e viste come elemento fondante della cittadinanza perdono centralità e si diffondono i nuovi modi di misurazione e riconoscimento propri dell'economia globale.Prior to the affirmation of the European citizenship created by the events of the French Revolution and of its narration weaved in with the supremacy of nations, the borders and the fordist homogeneity, the citizenship has presented itself as differentiated, separable and numerous and often it has been joined by other models of relation law/territory and of access to material and immaterial relations such as birth and residence. That, moreover, has taken place within the frame of thick and fluid relations between the city communities and the institutional petitions above them hierarchically. Built in such a such a way the European citizenship undergoes enormous tensions deriving from the crisis of nations, the development of new forms of global economy and the crisis/restorations accompanying it. The citizenship thus mutates and loses its organizing abilities and its elements of uniqueness. It breaks down into decomposable law and acquires fluidity of function and use by presenting itself partly as less capable of defending rights and partly as possible element of individual and complex strategies. Moreover it changes again its position during the state, city and above state entity play. Meanwhile the proximities, homogeneities, hierarchies and similarities that were once requested and seen as founding element of the citizenship now lose their central role and new methods of measurement and recognition belonging to the global economy start to spread

    Sharing a conceptual model of grid resources and services

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    Grid technologies aim at enabling a coordinated resource-sharing and problem-solving capabilities over local and wide area networks and span locations, organizations, machine architectures and software boundaries. The heterogeneity of involved resources and the need for interoperability among different grid middlewares require the sharing of a common information model. Abstractions of different flavors of resources and services and conceptual schemas of domain specific entities require a collaboration effort in order to enable a coherent information services cooperation. With this paper, we present the result of our experience in grid resources and services modelling carried out within the Grid Laboratory Uniform Environment (GLUE) effort, a joint US and EU High Energy Physics projects collaboration towards grid interoperability. The first implementation-neutral agreement on services such as batch computing and storage manager, resources such as the hierarchy cluster, sub-cluster, host and the storage library are presented. Design guidelines and operational results are depicted together with open issues and future evolutions.Comment: 4 pages, 0 figures, CHEP 200

    Pharmacogenetics of type 2 diabetes mellitus, the route toward tailored medicine

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    Type 2 diabetes mellitus (T2DM) is a chronic disease that has reached the levels of a global epidemic. In order to achieve optimal glucose control, it is often necessary to rely on combination therapy of multiple drugs or insulin because uncontrolled glucose levels result in T2DM progression and enhanced risk of complications and mortality. Several antihyperglycemic agents have been developed over time, and T2DM pharmacotherapy should be prescribed based on suitability for the individual patient's characteristics. Pharmacogenetics is the branch of genetics that investigates how our genome influences individual responses to drugs, therapeutic outcomes, and incidence of adverse effects. In this review, we evaluated the pharmacogenetic evidences currently available in the literature, and we identified the top informative genetic variants associated with response to the most common anti-diabetic drugs: metformin, DPP-4 inhibitors/GLP1R agonists, thiazolidinediones, and sulfonylureas/meglitinides. Overall, we found 40 polymorphisms for each drug class in a total of 71 loci, and we examined the possibility of encouraging genetic screening of these variants/loci in order to critically implement decision-making about the therapeutic approach through precision medicine strategies. It is possible then to anticipate that when the clinical practice will take advantage of the genetic information of the diabetic patients, this will provide a useful resource for the prevention of T2DM progression, enabling the identification of the precise drug that is most likely to be effective and safe for each patient and the reduction of the economic impact on a global scale
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