6 research outputs found

    University of Richmond Sustainability Report

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    The 2016 University of Richmond Sustainability Report represents where we are now, recognizes significant accomplishments, and provides a launching point for future endeavors. We all have a role to play in the continued stewardship of this great place. This document presents a summary of the data we collected. It serves the dual role of providing information on the considerable sustainability efforts underway and establishes a benchmark for our efforts as we move forward. There is much to be celebrated, and there is much to be done

    University of Richmond 2018 Climate Action Plan Update

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    In 2007, University of Richmond (UR) signed onto the the American College and University Presidents’ Climate Commitment, pledging to become carbon neutral by 2050. Three years later, UR published its first Climate Action Plan, a framework that committed the university to reduce its greenhouse gas (GHG) emissions 30% below 2009 levels by 2020 and 65% by 2035, on its way toward eliminating net carbon emissions. This Progress Report and GHG Inventory will explain UR’s emission calculation methodologies, provide a detailed analysis of the inventory, and document UR’s current GHG current footprint. University of Richmond’s Climate Action Plan aims to provide the UR community and its partners with a transparent roadmap of specific strategies for how the University will meet its GHG emission reduction targets. The Climate Action Plan will continue to be updated as needed, to incorporate new and innovative ideas and technologies

    Editors\u27 Introduction and Acknowledgements

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    An introduction to the journal Research in Outdoor Education, volume 6 is presented by the authors on behalf of the Coalition for Education in the Outdoors (CEO) Research Committee

    Expression of pluripotent stem cell reprogramming factors by prostate tumor initiating cells.

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    PURPOSE: We identified a discrete population of stem cell-like tumor cells expressing 5 essential transcription factors required to reprogram pluripotency in prostate tumor cell lines and primary prostate cancer tissue. MATERIALS AND METHODS: DU145 and PC3 human prostate cancer cell lines (ATCC), tumor tissue from patients with prostate cancer and normal prostate tissue were evaluated for the reprogramming factors OCT3/4 (Cell Signaling Technology), SOX2, Klf4 (Santa Cruz Biotechnology, Santa Cruz, California), Nanog (BioLegend) and c-Myc (Cell Signaling) by semiquantitative reverse transcriptase-polymerase chain reaction, histological and immunohistochemical analysis. Stem cell-like tumor cells were enriched by flow cytometric cell sorting using E-cadherin (R&D Systems) as a surface marker, and soft agar, spheroid and tumorigenicity assays to confirm cancer stem cell-like characteristics. RESULTS: mRNA expression of transcription factors OCT3/4 and SOX2 highly correlated in primary prostate tumor tissue samples. The number of OCT3/4 or SOX2 expressing cells was significantly increased in prostate cancer tissue compared to that in normal prostate or benign prostate hyperplasia tissue (p CONCLUSIONS: Data suggest that prostate tumor cells expressing pluripotent stem cell transcription factors are highly tumorigenic. Identifying such cells and their importance in prostate cancer growth could provide opportunities for novel targeting strategies for prostate cancer therapy
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