1,049 research outputs found
Implementation of the strategy: Problems and solutions
© 2015, Mediterranean Center of Social and Educational Research. All rights reserved. The paper deals with the implementation of the strategy as a key element of the strategic process. Developed organizational and management mechanism of the process of implementation of the strategy involves the exercise of choice of methods and resources management in accordance with the nature of the factors of internal processes (capacity) of the enterprise and the external environment in which it operates, and to exercise control on the basis of information on the implementation of the organization's processes and stakeholder satisfaction in accordance with the principles of quality management. To evaluate the effectiveness of the implementation of a procedure for strategic verification. Statistical processing of the data obtained by the method of rank correlation has identified strategic indicators, most affecting the level of strategic impact. Integrated use of expert and mathematical processing of information provides a more complete picture of the impact of the implementation of the strategy
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Fast bistable intensive light scattering in helix-free ferroelectric liquid crystals.
A new type of ferroelectric liquid crystal (FLC) is considered, where the reorientation of the director (main optical axes) at the interaction of an electric field with the FLC's spontaneous polarization is due to the movement of spatially localized waves with a stationary profile: solitons arise at the transition due to the Maxwellian mechanism of energy dissipation. Under certain conditions, the appearance of such waves leads to the formation of a structure of transient domains, and as a consequence, to the scattering of light. The Maxwellian mechanism of energy dissipation allows one to reduce the electric field strength at which the maximum efficiency of light scattering is achieved down to 2-3 V/ÎĽm and to increase the frequency of light modulation up to 3-5 kHz. Intensive bistable light scattering in an electro-optical cell filled with a specially designed helix-free FLC was studied, and a stable scattering state can be switched on and off for a few tens of microseconds and memorized for a few tens of seconds.Russian Academy of SciencesThis is the author accepted manuscript. The final version is available from The Optical Society via http://dx.doi.org/10.1364/AO.55.00348
Clustering in light nuclei in fragmentation above 1 A GeV
The relativistic invariant approach is applied to analyzing the 3.3 A GeV
Ne fragmentation in a nuclear track emulsion. New results on few-body
dissociations have been obtained from the emulsion exposures to 2.1 A GeV
N and 1.2 A GeV Be nuclei. It can be asserted that the use of the
invariant approach is an effective means of obtaining conclusions about the
behavior of systems involving a few He nuclei at a relative energy close to 1
MeV per nucleon. The first observations of fragmentation of 1.2 A GeV B
and C nuclei in emulsion are described. The presented results allow one
to justify the development of few-body aspects of nuclear astrophysics.Comment: 7 pages, 8 figures, 3 tables, Nuclear Physics in Astrophysics-2,
16-20 May, 2005 (ATOMKI), Debrecen, Hungar
Fragmentation of relativistic nuclei in peripheral interactions in nuclear track emulsion
The technique of nuclear track emulsions is used to explore the fragmentation
of light relativistic nuclei down to the most peripheral interactions - nuclear
"white" stars. A complete pattern of therelativistic dissociation of a B
nucleus with target fragment accompaniment is presented. Relativistic
dissociation Be is explored using significant statistics and
a relative contribution of Be decays from 0 and 2 states is
established. Target fragment accompaniments are shown for relativistic
fragmentation N3He+H and Ne5He. The leading role of the
electromagnetic dissociation on heavy nuclei with respect to break-ups on
target protons is demonstrated in all these cases. It is possible to conclude
that the peripheral dissociation of relativistic nuclei in nuclear track
emulsion is a unique tool to study many-body systems composed of lightest
nuclei and nucleons in the energy scale relevant for nuclear astrophysics.Comment: 15 pages, 4 figures, 4 tables, conference: Relativistic nuclear
physics: from Nuclotron to LHC energies, Kiev, June 18-22, 200
Autoimmune polyglandular syndrome type 1 and eye damage
Autoimmune polyendocrine syndrome type 1 (APS type 1) is a disease characterized by a variety of clinical manifestations resulting from the involvement of multiple endocrine and non-endocrine organs in the pathological process. APS type 1 is a rare genetically determined disease with autosomal recessive inheritance. Mutations in the autoimmune regulator gene (AIRE) lead to a disruption of the mechanism of normal antigen expression and the formation of abnormal clones of immune cells, and can cause autoimmune damage to organs. Within APS type 1, the most common disorders are primary adrenal insufficiency, hypoparathyroidism, and chronic candidiasis. Some understudied clinical manifestations of APS type 1 are autoimmune pathological processes in the eye: keratoconjunctivitis, dry eye syndrome, iridocyclitis, retinopathy, retinal detachment, and optic atrophy. This review presents the accumulated experimental and clinical data on the development of eye damage of autoimmune nature in APS type 1, as well as the laboratory and instrumental methods used for diagnosing the disease. Changes in the visual organs in combination with clinical manifestations of hypoparathyroidism, adrenal insufficiency and candidiasis should lead the clinical doctor to suspect the presence of APS type 1 and to examine the patient comprehensively. Timely genetic counselling will allow early identifi cation of the disease, timely prescription of appropriate treatment and prevention of severe complications
Algorithm engineering for optimal alignment of protein structure distance matrices
Protein structural alignment is an important problem in computational
biology. In this paper, we present first successes on provably optimal pairwise
alignment of protein inter-residue distance matrices, using the popular Dali
scoring function. We introduce the structural alignment problem formally, which
enables us to express a variety of scoring functions used in previous work as
special cases in a unified framework. Further, we propose the first
mathematical model for computing optimal structural alignments based on dense
inter-residue distance matrices. We therefore reformulate the problem as a
special graph problem and give a tight integer linear programming model. We
then present algorithm engineering techniques to handle the huge integer linear
programs of real-life distance matrix alignment problems. Applying these
techniques, we can compute provably optimal Dali alignments for the very first
time
Electromagnetic dissociation of relativistic B nuclei in nuclear track emulsion
Experimental data on fragmentation channels in peripheral interactions of
B nuclei in nuclear track emulsions are presented. A detailed analysis made
it possible to justify selections of events of the electromagnetic-dissociation
process B Be + \emph{p} and to estimate its cross section. Events of
C peripheral dissociation that were observed in the same exposure are
described.Comment: 12 pages, 10 figures, 4 tables, Published in
Phys.Atom.Nucl.72:690-701,200
Topology of "white" stars in relativistic fragmentation of light nuclei
In the present paper, experimental observations of the multifragmentation
processes of light relativistic nuclei carried out by means of emulsions are
reviewed. Events of the type of "white" stars in which the dissociation of
relativistic nuclei is not accompanied by the production of mesons and the
target-nucleus fragments are considered.
A distinctive feature of the charge topology in the dissociation of the Ne,
Mg, Si, and S nuclei is an almost total suppression of the binary splitting of
nuclei to fragments with charges higher than 2. The growth of the nuclear
fragmentation degree is revealed in an increase in the multiplicity of singly
and doubly charged fragments with decreasing charge of the non-excited part of
the fragmenting nucleus.
The processes of dissociation of stable Li, Be, B, C, N, and O isotopes to
charged fragments were used to study special features of the formation of
systems consisting of the lightest , d, and t nuclei. Clustering in
form of the He nucleus can be detected in "white" stars via the
dissociation of neutron-deficient Be, B, C, and N isotopes.Comment: 20 pages, 3 figures, 9 tables, conference: Conference on Physics of
Fundamental Interactions, Moscow, Russia, 1-5 Mar 2004.(Author's translation
Distributed Computing Grid Experiences in CMS
The CMS experiment is currently developing a computing system capable of serving, processing and archiving the large number of events that will be generated when the CMS detector starts taking data. During 2004 CMS undertook a large scale data challenge to demonstrate the ability of the CMS computing system to cope with a sustained data-taking rate equivalent to 25% of startup rate. Its goals were: to run CMS event reconstruction at CERN for a sustained period at 25 Hz input rate; to distribute the data to several regional centers; and enable data access at those centers for analysis. Grid middleware was utilized to help complete all aspects of the challenge. To continue to provide scalable access from anywhere in the world to the data, CMS is developing a layer of software that uses Grid tools to gain access to data and resources, and that aims to provide physicists with a user friendly interface for submitting their analysis jobs. This paper describes the data challenge experience with Grid infrastructure and the current development of the CMS analysis system
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