Analisis Pengaruh Budaya Organisasi Dan Kompensasi Terhadap Kinerja Karyawan Dengan Motivasi Sebagai Variabel Intervening (Studi Kasus Pada PT. Lg Bagian Penjualan Indonesia Semarang)

The problems that occurred in the employee portion of sales LG Indonesia Semarang is adecline in performance is indicated by not achieving the target for 2015. The employeeperformance and motivation is also thought to be influenced by factors of organizationalculture and also compensation deemed not feasible by most employees. This study aimedto analyze the influence of organizational culture on the motivation and compensationand employee performance parts sales LG Indonesia Semarang. The population used inthis study were all employees of LG Indonesia Semarang. The sampling technique usedwas purposive sampling. Criteria samples taken were all employees of the salesdepartment LG Indonesia Semarang who have worked more than two years are 71nurses. The method of collecting the data in this study using questionnaires andinterviews. Methods of data analysis using path analysis. Based on the research,organizational culture and compensation have a positive effect on motivation andperformance, while motivation is also a positive effect on performance. Based on theresults Sobel Test to determine whether there is mediating the relationship between theindependent and dependent variables, it is known that motivation mediates the effect ofcompensation and organizational culture on performance

Kajian Pengelolaan Lahan Subdas Secang Kulonprogo YOGYAKARTA

Penelitian ini bertujuan untuk mengevaluasi kemampuan lahan, menyusun arahan penggunaanlahan dan mengkaji pengelolaan lahan SubDAS Secang. Metode yang digunakan dalam penelitianadalah sampel terpilih pada 48 satuan lahan. Penelitian menunjukkan bahwa kemampuan lahanSubDAS Secang terdiri atas kelas lahan I seluas 187 ha, kelas lahan II seluas 147 ha, kelas lahan IIIseluas 515,2 ha, kelas lahan IV seluas 1522,7 ha, kelas lahan V seluas 7,3 ha dan kelas lahan VI seluas1223,2 ha. Arahan penggunaan lahan SubDAS Secang berupa pertanian lahan basah seluas 326,85 ha,kawasan permukiman dan budidaya tanaman semusim seluas 200,55 ha, kawasan budidaya tanamanlahan kering seluas 525,81 ha, kawasan budidaya tanaman tahunan seluas 1981,31 ha, kawasanpenyangga seluas 716,54 ha. Pengelolaan lahan memberikan pedoman pemanfaatan lahan; daerah hilirsebagai daerah pemanfaatan untuk pertanian irigasi; daerah tengah diperuntukan permukiman danpembudidayaan tanaman lahan kering; serta daerah hulu sebagai daerah imbuhan diperuntukkanwanatani dan hutan penyangga

Number of interactions per autosome pair.

<p>Results are based on the significant LD block pairs involving loci. The barplot on the right shows the average number of interactions per LD block for each chromosome. Chromosomes , , and show the highest participation in interactions while the fewest interactions per LD block are on chromosome .</p

ImAP p-value distribution.

<p>Distribution of the p-values of the original data (black) and five simulations under the null hypothesis of no allelic incompatibilities (grey). The y-axis is concentrated on the interesting area of high density. The inset shows a zoom on the small p-values in scale.</p

Expected genotype probabilities.

<p>Expected genotype probabilities in the offspring for each possible allele combination of the parents.</p

Correlated interaction profiles.

<p>(A) Schematic showing relationship between epistatic interactions and molecular pathways. The genes x and y share three allele incompatibilities with genes from a parallel pathway. In the schematic interaction matrix on the right these shared interactions lead to correlated interaction profiles (rows are correlated; dashed line). (B) Example of two loci on chromosomes and sharing a common interacting locus on chromosome . The position of the loci on the chromosomes is indicated by red bars. The putatively causal genes are written below the loci. Arrows indicate interactions with ImAP p-values , the dashed line indicates a high congruence score ().</p

Additional file 6 of Importance of rare gene copy number alterations for personalized tumor characterization and survival analysis

Table S5. LINCS perturbation experiments used. (TXT 1054 kb

Assessing the linear bias correction.

<p>Linear regression plots for trained (predicted) versus tested based on a second, independent reference data set for the different combinations of redundant subsets. Red line: interactions reported in only one database. Green and blue line: corrected and uncorrected for interactions reported in at least two databases. Orange line: Using the maximum of the individual instead of the sum. Ideally, all predictions should be along the diagonal. The bias corrected scores are clearly better predictors of the true interaction likelihood.</p

Venn diagram of the overlap between Bioverse, HiMAP and STRING.

<p>(A) Overlap between genes. Approximately of the genes are common to at least two databases. (B) Overlap between interactions. Only 2.8% of the interactions are reported in more than one database.</p

Coiled-Coil Proteins Facilitated the Functional Expansion of the Centrosome

<div><p>Repurposing existing proteins for new cellular functions is recognized as a main mechanism of evolutionary innovation, but its role in organelle evolution is unclear. Here, we explore the mechanisms that led to the evolution of the centrosome, an ancestral eukaryotic organelle that expanded its functional repertoire through the course of evolution. We developed a refined sequence alignment technique that is more sensitive to coiled coil proteins, which are abundant in the centrosome. For proteins with high coiled-coil content, our algorithm identified 17% more reciprocal best hits than BLAST. Analyzing 108 eukaryotic genomes, we traced the evolutionary history of centrosome proteins. In order to assess how these proteins formed the centrosome and adopted new functions, we computationally emulated evolution by iteratively removing the most recently evolved proteins from the centrosomal protein interaction network. Coiled-coil proteins that first appeared in the animal–fungi ancestor act as scaffolds and recruit ancestral eukaryotic proteins such as kinases and phosphatases to the centrosome. This process created a signaling hub that is crucial for multicellular development. Our results demonstrate how ancient proteins can be co-opted to different cellular localizations, thereby becoming involved in novel functions.</p></div