328 research outputs found

    State-of-the-art in Power Line Communications: from the Applications to the Medium

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    In recent decades, power line communication has attracted considerable attention from the research community and industry, as well as from regulatory and standardization bodies. In this article we provide an overview of both narrowband and broadband systems, covering potential applications, regulatory and standardization efforts and recent research advancements in channel characterization, physical layer performance, medium access and higher layer specifications and evaluations. We also identify areas of current and further study that will enable the continued success of power line communication technology.Comment: 19 pages, 12 figures. Accepted for publication, IEEE Journal on Selected Areas in Communications. Special Issue on Power Line Communications and its Integration with the Networking Ecosystem. 201

    Love Data @ UH: Collaborating with Campus Partners to Promote Data Services

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    In this paper, the authors discuss their academic library’s role in promoting collaboration and visibility among various data service providers on campus, including those provided by the library. Bringing together these data providers for a one-day event at the library, Love Data @ UH, speakers and audience members were able to meet and talk about data management, data visualization, and other data-related services provided at University of Houston campus. The authors also discuss how the event was planned, with recommendations for others considering holding a similar event

    Subgroups of cancer patients with unique pain and fatigue experiences during chemotherapy

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    Context. Some cancer patients experience pain and fatigue, whereas others experience only one of the two symptoms. Yet, it is not clear who experiences these unique patterns and why. Objectives. This study aimed to identify subgroups of cancer patients with unique pain and fatigue experiences in two different chemotherapy cycles to examine how selected factors influenced subgroup membership and identify how subgroups differed in concurrently measured functional limitation outcome. Methods. The sample included 276 patients with diverse cancer types from four U.S. sites. To investigate subgroups, latent profile analyses were performed. Multinomial logistic regression and one-way analysis of variance-type analyses were conducted to examine the influencing variables of subgroup membership and to examine differences among subgroups in patient outcome. Results. The high-pain/high-fatigue (HPHF) and low-pain/low-fatigue subgroups were found at both time points. The low-pain/high-fatigue subgroup was present only in the first chemotherapy cycle. Pain and fatigue levels significantly differentiated subgroups at each time point (all P \u3c 0.05). Across the two time points, experiencing higher depressed mood increased the risk to be in the HPHF subgroup (all P \u3c 0.01). The HPHF subgroup had the most serious limitations in activities (all P \u3c 0.01). Conclusion. This study confirmed the existence of a unique symptom experience of pain and fatigue. This pattern should be acknowledged for symptom assessment and management

    Report of large whale restraint workshop

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    Location: Carriage House, Woods Hole Oceanographic Institution, Woods Hole, MA 02543. Date: February 7th & 8th 2006A number of large cetacean species are seriously injured and killed by entanglement in fishing gear used in the waters off the eastern United States and Canada. Entanglement most frequently involves rope or lines wrapped around the head, the flippers, body, in the mouth, around the tail flukes or any combination of the aforementioned body parts. Consequences of entanglement are particularly grave for North Atlantic right whales, which currently number about 300 whales and are declining due, in part, to this entanglement-related mortality. Right whales are frequently intractable and are very difficult and potentially unsafe to work with while attempting to disentangle the animal. Modifications and technological advances are needed to control, restrain and overall increase the success rate at which right whales are able to be cut free from entangling gear.National Marine Fisheries Servic

    Identifying Structural Flow Defects in Disordered Solids Using Machine-Learning Methods

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    We use machine-learning methods on local structure to identify flow defects—or particles susceptible to rearrangement—in jammed and glassy systems. We apply this method successfully to two very different systems: a two-dimensional experimental realization of a granular pillar under compression and a Lennard-Jones glass in both two and three dimensions above and below its glass transition temperature. We also identify characteristics of flow defects that differentiate them from the rest of the sample. Our results show it is possible to discern subtle structural features responsible for heterogeneous dynamics observed across a broad range of disordered materials

    The effect of fingolimod on regulatory T cells in a mouse model of brain ischaemia

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    Background: The role of the immune system in stroke is well-recognised. Fingolimod, an immunomodulatory agent licensed for the management of relapsing-remitting multiple sclerosis, has been shown to provide benefit in rodent models of stroke. Its mechanism of action, however, remains unclear. We hypothesised fingolimod increases the number and/or function of regulatory T cells (Treg), a lymphocyte population which promotes stroke recovery. The primary aim of this study was to rigorously investigate the effect of fingolimod on Tregs in a mouse model of brain ischaemia. The effect of fingolimod in mice with common stroke-related comorbidities (ageing and hypercholesteremia) was also investigated. Methods: Young (15–17 weeks), aged C57BL/6 mice (72–73 weeks), and ApoE?/? mice fed a high-fat diet (20–21 weeks) underwent permanent electrocoagulation of the left middle cerebral artery. Mice received either saline or fingolimod (0.5 mg/kg or 1 mg/kg) at 2, 24, and 48 h post-ischaemia via intraperitoneal injection. Another cohort of young mice (8–9, 17–19 weeks) received short-term (5 days) or long-term (10 days) fingolimod (0.5 mg/kg) treatment. Flow cytometry was used to quantify Tregs in blood, spleen, and lymph nodes. Immunohistochemistry was used to quantify FoxP3+ cell infiltration into the ischaemic brain. Results: Fingolimod significantly increased the frequency of Tregs within the CD4+ T cell population in blood and spleen post-ischaemia in all three mouse cohorts compared to untreated ischemic mice. The highest splenic Treg frequency in fingolimod-treated mice was observed in ApoE?/? mice (9.32 ± 1.73% vs. 7.8 ± 3.01% in young, 6.09 ± 1.64% in aged mice). The highest circulating Treg frequency was also noted in ApoE?/? mice (8.39 ± 3.26% vs. 5.43 ± 2.74% in young, 4.56 ± 1.60% in aged mice). Fingolimod significantly increased the number of FoxP3+ cells in the infarct core of all mice. The most pronounced effects were seen when mice were treated for 10 days post-ischaemia. Conclusions: Fingolimod increases Treg frequency in spleen and blood post-ischaemia and enhances the number of FoxP3+ cells in the ischaemic brain. The effect of fingolimod on this regulatory cell population may underlie its neuroprotective activity and could be exploited as part of future stroke therapy

    The Influence of Literacy on Patient-Reported Experiences of Diabetes Self-Management Support

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    Variability in disease-related outcomes may relate to how patients experience self-management support in clinical settings
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