Dynamics of Racial Residential Segregation and Gentrification in New York City

Racial residential segregation is interconnected with several other phenomena such as income inequalities, property values inequalities, and racial disparities in health and education. Furthermore, recent literature suggests the phenomenon of gentrification as a cause of perpetuation or increase of racial residential segregation in some American cities. In this paper, we analyze the dynamics of racial residential segregation for white, black, Asian, and Hispanic citizens in New York City in 1990, 2000, and 2010. It was possible to observe that segregation between white and Hispanic citizens and between white and Asian ones has grown, while segregation between white and black is relatively stable. Furthermore, we analyzed the per capita income and the Gini coefficient in each segregated zone, showing that the highest inequalities occur in the zones where there is an overlap of high-density zones of pair of races. Focusing on the changing of the density of population across the city during these 20 years, and by analyzing white and black people's segregation, our analysis reveals that a positive flux of white (black) people is associated with a substantial increase (decrease) of the property values, as compared with the city mean. Furthermore, by clustering the region with the higher density of black citizens, we measured the variation of area and displacement of the four most significant clusters from 1990 to 2010. The large displacements ( & AP; 1.6 k m ) observed for two of these clusters, namely, one in the neighborhood of Harlem and the other inside the borough of Brooklyn, led to the emergence of typically gentrified regions

GROWTH IN VOLUME OF Araucaria angustifolia (Bertol.) Kuntze IN SERRA DO SUDESTE IN THE STATE OF RIO GRANDE DO SUL, BRAZIL

This research aims at analyzing the growth in volume of Araucaria angustifolia (Bertol.) Kuntze in the region of Serra do Sudeste (Rio Grande do Sul, Brazil) and also proposing a growth equation in volume. Data were obtained by trunk analysis, considering, firstly, transverse sections of trees at 0.10 and 1.30 m heigths; after-words, the measurement taken into accoumt was 2.0 in 2.0 m height. Such trees were cut in natural settlements, having resulted the volume per age. The wirk demonstrated that species in this area has significant increments, reaching, after 60 years, a volume eithout bark of 0.6866 m3, with an annual average increament in volume without bark of of 0.01585 m3/year.Os objetivos desta pesquisa foram analisar o crescimento em volume de Araucaria angustifolia (Bertol.) Kuntze na regi\ue3o da Serra do Sudeste e ajustar uma equa\ue7\ue3o de crescimento em volume. Os dados foram obtidos por an\ue1lise de tronco, de se\ue7\uf5es transversais nas alturas de 0,10 m, 1,30 m e, ap\uf3s, de 2 em 2m, de \ue1rvores abatidas de povoamentos naturais, tendo o volume resultado por idade. O trabalho demonstrou que a esp\ue9cie nessa regi\ue3o tem incrementos significativos, atingindo, aos 60 anos, o volume sem casca m\ue9dio igual a 0,6866 m3, com um incremento m\ue9dio anual em volume sem casca de 0,01585 m3/ano

Modified Timed Up and Go Test for Tendency to Fall and Balance Assessment in Elderly Patients With Gait Instability

Objective: To compare the results from the modified Timed Up and Go Test (TUG) with posturographic variables, the subjective perception of disability due to gait instability, and the number of falls in a sample of the elderly population with imbalance, to confirm that the TUG Test is a useful clinical instrument to assess the tendency to fall in individuals of this age group. Materials and Methods: Cross-sectional study conducted in a tertiary university hospital, in 174 people aged 65 years or older with gait instability. Modified TUG Test was performed; time, step count and the need for support during the test were the analyzed variables. They were compared with the number of falls, Computerized Dynamic Posturography scores, and questionnaires scores (Dizziness Handicap Inventory and a shortened version of the Falls Efficacy Scale-International). Results: The average time to complete the TUG Test was 21.24 +/- 8.18 s, and the average step count was 27.36 +/- 7.93. One hundred two patients (58.6%) required no support to complete the test, whereas the other 72 (41.4%) used supports. The time taken to complete the Test was significantly related with having or not having fallen in the previous year, with the scores of the questionnaires, and with various parameters of dynamic posturography. A higher percentage of patients who took more than 15 s had fallen in the previous year than those who took up to 15 s to complete the test [P = 0.012; OR = 2.378; 95% CI (1.183, 4.780)]. No significant correlation was found between the step count and the number of falls in the previous year, with falling during the test or not, or with being a single or a frequent faller. No relation was found between the need for supports and the number of falls, with having or not having fallen in the previous year, or with being a single or frequent faller. Conclusion: The modified TUG Test is in relation with the presence or absence of falls. Time is the essential parameter for analyzing the risk of falling and the 15-s threshold is a good value to differentiate elderly patients at high risk of falling. Unique Identifier: NCT03034655, www.clinicaltrials.gov

Presbyvestibulopathy, Comorbidities, and Perception of Disability: A Cross-Sectional Study

Objective: To assess the perception of disability in patients with presbyvestibulopathy and to determine the factors (demographic, balance test scores, and comorbidities) that determine higher levels of disability. Material and Methods: This was a cross-sectional study conducted in a tertiary university hospital. There were 103 patients who fulfilled the diagnostic criteria for presbyvestibulopathy and were included. Dizziness Handicap Inventory (DHI) score was the main variable used to quantify disability. Influence on DHI score, sex, age, time of evolution, equilibriometric parameters (posturographic scores and timed up and go test), history of falls, comorbidities (high blood pressure, diabetes, and dyslipidemia), psychotropic drug use, tobacco or alcohol use, living environment (urban or rural), and active lifestyle were analyzed. Results: Most of the DHI scores showed a moderate (46 patients, 44.7%) or severe (39 participants, 37.9%) handicap. DHI scores were higher in women (59.8 vs. 36.1, p < 0.001), patients with obesity (58.92 vs. 48.68; p = 0.019), benzodiazepine (59.9 vs. 49.1, p = 0.008) or other psychotropic drug (60.7 vs. 49.2, p = 0.017) users, and fallers (57.1 vs. 47.3, p = 0.048). There was also a significant positive correlation between DHI score, time (Rho coefficient: 0.371, p < 0.001), and steps (Rho coefficient: 0.284, p = 0.004) used in the TUG and with the short FES-I questionnaire (a shortened version of the Falls Efficacy Scale-International) score (Rho coefficient: 0.695, p < 0.001). DHI scores were lower in alcohol consumers than in non-drinkers (46.6 vs. 56, p = 0.048). No significant correlation was found between DHI scores and age, time of evolution, posturographic scores, comorbidities, environment (rural or urban), or active lifestyle. Conclusion: Most patients with presbyvestibulopathy show an important subjective perception of disability in relation to their symptoms. This perception is substantially higher in women than in men. The most influential factors are difficulties in walking, fear of falling, and obesity. Unique Identifier: NCT03034655, www.clinicaltrials.gov

Surgical treatment of onychomatricoma with dermal graft : case report.

Relata-se caso de mulher de 58 anos que apresentou espessamento da unha do h?lux esquerdo acompanhado por crescimento lento de les?o n?dulo-vegetante no leito ungueal. Ap?s bi?psia incisional com exame anatomopatol?gico a les?o foi diagnosticada como onicomatricoma, uma rara neoplasia benigna espec?fica do complexo ungueal. O tratamento de escolha do onicomatricoma ? cir?rgico, sendo realizado no presente caso a reconstru??o do leito ungueal atrav?s de enxerto d?rmico.Case report of a 58-year-old woman that presented with nail thickening of the left hallux in association with a slow- growing nodular/vegetative lesion on the nail matrix. After incisional biopsy and histopathological examination, the lesion was diagnosed as an onychomatricoma, a rare benign neoplasia that occurs specifically in the nail matrix. The treatment of choice for the onychomatricoma is surgery and in the present case, a reconstruction of the ungula matrix was achieved through a dermal graft

Platelet thrombin receptor antagonism and atherothrombosis

Clinical manifestations of atherothrombotic disease, such as acute coronary syndromes, cerebrovascular events, and peripheral arterial disease, are major causes of mortality and morbidity worldwide. Platelet activation and aggregation are ultimately responsible for the progression and clinical presentations of atherothrombotic disease. The current standard of care, dual oral antiplatelet therapy with aspirin and the P2Y12 adenosine diphosphate (ADP) receptor inhibitor clopidogrel, has been shown to improve outcomes in patients with atherothrombotic disease. However, aspirin and P2Y12 inhibitors target the thromboxane A2 and the ADP P2Y12 platelet activation pathways and minimally affect other pathways, while agonists such as thrombin, considered to be the most potent platelet activator, continue to stimulate platelet activation and thrombosis. This may help explain why patients continue to experience recurrent ischaemic events despite receiving such therapy. Furthermore, aspirin and P2Y12 receptor antagonists are associated with bleeding risk, as the pathways they inhibit are critical for haemostasis. The challenge remains to develop therapies that more effectively inhibit platelet activation without increasing bleeding complications. The inhibition of the protease-activated receptor-1 (PAR-1) for thrombin has been shown to inhibit thrombin-mediated platelet activation without increasing bleeding in pre-clinical models and small-scale clinical trials. PAR-1 inhibition in fact does not interfere with thrombin-dependent fibrin generation and coagulation, which are essential for haemostasis. Thus PAR-1 antagonism coupled with existing dual oral antiplatelet therapy may potentially offer more comprehensive platelet inhibition without the liability of increased bleeding