578 research outputs found

    Extension of the fuzzy integral for general fuzzy set-valued information

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    The fuzzy integral (FI) is an extremely flexible aggregation operator. It is used in numerous applications, such as image processing, multicriteria decision making, skeletal age-at-death estimation, and multisource (e.g., feature, algorithm, sensor, and confidence) fusion. To date, a few works have appeared on the topic of generalizing Sugeno's original real-valued integrand and fuzzy measure (FM) for the case of higher order uncertain information (both integrand and measure). For the most part, these extensions are motivated by, and are consistent with, Zadeh's extension principle (EP). Namely, existing extensions focus on fuzzy number (FN), i.e., convex and normal fuzzy set- (FS) valued integrands. Herein, we put forth a new definition, called the generalized FI (gFI), and efficient algorithm for calculation for FS-valued integrands. In addition, we compare the gFI, numerically and theoretically, with our non-EP-based FI extension called the nondirect FI (NDFI). Examples are investigated in the areas of skeletal age-at-death estimation in forensic anthropology and multisource fusion. These applications help demonstrate the need and benefit of the proposed work. In particular, we show there is not one supreme technique. Instead, multiple extensions are of benefit in different contexts and applications

    Serotonin Transporter (5-HTTLPR) Genotype and Childhood Trauma are Associated with Individual Differences in Decision Making

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    The factors that influence individual differences in decision making are not yet fully characterized, but convergent evidence is accumulating that implicates serotonin (5-HT) system function. Therefore, both genes and environments that influence serotonin function are good candidates for association with risky decision making. In the present study we examined associations between common polymorphisms in the serotonin transporter gene (SLC6A4; 5-HTTLPR and rs25531), the experience of childhood trauma and decision making on the Iowa gambling task (IGT) in 391 (64.5% female) healthy Caucasian adults. Homozygosity for the 5-HTTLPR L allele was associated with riskier decision making in the first block of 20 trials (i.e., decision making under ambiguity, p = 0.004). In addition, mean IGT performance was significantly worse in blocks 3–5 (i.e., decision making under risk, p ≤ 0.05) for those participants who reported experiencing higher levels of childhood trauma. Our findings add to the growing evidence that genetic variation in the 5-HT system is associated with individual differences in decision making under ambiguity; and we report that the experience of childhood trauma is associated with relatively poor decision making under risk

    Relationship Between Foveal Cone Specialization and Pit Morphology in Albinism

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    Purpose.Albinism is associated with disrupted foveal development, though intersubject variability is becoming appreciated. We sought to quantify this variability, and examine the relationship between foveal cone specialization and pit morphology in patients with a clinical diagnosis of albinism. Methods. We recruited 32 subjects with a clinical diagnosis of albinism. DNA was obtained from 25 subjects, and known albinism genes were analyzed for mutations. Relative inner and outer segment (IS and OS) lengthening (fovea-to-perifovea ratio) was determined from manually segmented spectral domain-optical coherence tomography (SD-OCT) B-scans. Foveal pit morphology was quantified for eight subjects from macular SD-OCT volumes. Ten subjects underwent imaging with adaptive optics scanning light ophthalmoscopy (AOSLO), and cone density was measured. Results. We found mutations in 22 of 25 subjects, including five novel mutations. All subjects lacked complete excavation of inner retinal layers at the fovea, though four subjects had foveal pits with normal diameter and/or volume. Peak cone density and OS lengthening were variable and overlapped with that observed in normal controls. A fifth hyper-reflective band was observed in the outer retina on SD-OCT in the majority of the subjects with albinism. Conclusions. Foveal cone specialization and pit morphology vary greatly in albinism. Normal cone packing was observed in the absence of a foveal pit, suggesting a pit is not required for packing to occur. The degree to which retinal anatomy correlates with genotype or visual function remains unclear, and future examination of larger patient groups will provide important insight on this issue

    Precio: Private Aggregate Measurement via Oblivious Shuffling

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    We introduce Precio, a new secure aggregation method for computing layered histograms and sums over secret shared data in a client-server setting. Precio is motivated by ad conversion measurement scenarios, where online advertisers and ad networks want to measure the performance of ad campaigns without requiring privacy-invasive techniques, such as third-party cookies. Precio has linear (communication) complexity in the number of data points and guarantees differentially private outputs. We formally analyze its security and privacy and present a thorough performance evaluation. The protocol supports much larger domains than Prio. It supports much more flexible aggregates than the DPF-based solution and in some settings has up to four orders of magnitude better performance

    Nutrient Digestibility and Fermentation of Brown Midrib Corn Fed to Growing Beef Steers

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    A digestion study evaluated three corn silage hybrids for growing crossbred steers. The three hybrids were: a standard corn silage hybrid which served as the control, a brown midrib hybrid (bm3), and an experimental bm3 hybrid with a softer endosperm. Both bm3 hybrids had greater organic matter and fiber digestibility compared to the control corn silage. However, no differences were observed between the two bm3 hybrids. Rumen pH was reduced for BM3 and BM3-EXP compared to the control suggesting greater rumen fermentation. In vitro gas production was increased for the bm3 hybrids compared to the control further supporting greater rumen fermentation

    Nutrient Digestibility and Fermentation of Brown Midrib Corn Fed to Growing Beef Steers

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    A digestion study evaluated three corn silage hybrids for growing crossbred steers. The three hybrids were: a standard corn silage hybrid which served as the control, a brown midrib hybrid (bm3), and an experimental bm3 hybrid with a softer endosperm. Both bm3 hybrids had greater organic matter and fiber digestibility compared to the control corn silage. However, no differences were observed between the two bm3 hybrids. Rumen pH was reduced for BM3 and BM3-EXP compared to the control suggesting greater rumen fermentation. In vitro gas production was increased for the bm3 hybrids compared to the control further supporting greater rumen fermentation

    The effect of corn silage hybrid and inclusion on performance of finishing steers and silage hybrid effects on digestibility and performance of growing steers

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    Three experiments evaluated the effects of three corn silage hybrids, inclusion, and nutrient digestibility in growing and finishing diets. The three hybrids tested included a control (CON), a hybrid containing a brown midrib (bm3) trait (BM3), and an experimental bm3 hybrid with the soft endosperm trait (BM3-SOFT). Experiment 1 utilized 360 crossbred steers (body weight [BW] = 334; SD = 25 kg) to evaluate inclusion of silage in a finishing diet at (15% or 45% of diet dry matter [DM]) and silage hybrid (CON, BM3, or BM3-SOFT). Experiment 2 and 3 utilized 216 crossbred steers (BW = 324; SD = 10 kg) and six ruminally fistulated steers (BW = 274; SD = 27 kg), respectively, to evaluate effects of either CON, BM3, or BM3-SOFT silage hybrids on performance and nutrient digestibility in growing diets. In Exp. 1, there was a silage inclusion × hybrid interaction for average daily gain (ADG) and gain-to-feed ratio (G:F). All treatments with 15% silage had greater (P ≤ 0.04) ADG and G:F compared with 45% silage. Cattle fed BM3-SOFT had greater ADG and G:F than cattle fed CON or BM3 when silage was included at 15% of the diet. When silage was fed at 45% of the diet DM, ADG did not differ between cattle fed either bm3 hybrid. Cattle fed BM3 had the greatest G:F (P \u3c 0.01), with no difference between BM3-SOFT and CON. At 15% silage inclusion, hot carcass weight (HCW) was greater (P \u3c 0.01) for cattle fed BM3-SOFT compared with cattle fed CON and BM3 but did not differ between cattle fed BM3 and CON. At 45% silage inclusion, steers fed either bm3 hybrid did not differ in HCW but were both heavier (P \u3c 0.01) compared with cattle fed CON. In Exp. 2, ending BW, dry matter intake (DMI), and ADG were greater (P \u3c 0.01) for steers fed either bm3 hybrid compared to steers fed the CON, but not different between steers fed the bm3 hybrids. There were no differences (P = 0.26) in G:F between the silage hybrids. In Exp. 3, steers fed either bm3 had greater (P \u3c 0.01) neutral detergent fiber (NDF) and acid detergent fiber (ADF) digestibility than steers fed the CON. Ruminal pH was lower (P \u3c 0.01), and total volatile fatty acid (VFA) concentration was greater (P \u3c 0.01) for steers fed bm3 hybrids compared to steers fed CON. Feeding silage with the bm3 trait improved fiber digestibility, which increased DMI and subsequent ADG in high-forage growing diets. Feeding corn silage with the bm3 trait improved performance compared to non-bm3 corn silage when included above typical roughage concentration

    Mitochondrial DNA and trade data support multiple origins of Helicoverpa armigera (Lepidoptera, Noctuidae) in Brazil

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    The Old World bollworm Helicoverpa armigera is now established in Brazil but efforts to identify incursion origin(s) and pathway(s) have met with limited success due to the patchiness of available data. Using international agricultural/horticultural commodity trade data and mitochondrial DNA (mtDNA) cytochrome oxidase I (COI) and cytochrome b (Cyt b) gene markers, we inferred the origins and incursion pathways into Brazil. We detected 20 mtDNA haplotypes from six Brazilian states, eight of which were new to our 97 global COI-Cyt b haplotype database. Direct sequence matches indicated five Brazilian haplotypes had Asian, African, and European origins. We identified 45 parsimoniously informative sites and multiple substitutions per site within the concatenated (945 bp) nucleotide dataset, implying that probabilistic phylogenetic analysis methods are needed. High diversity and signatures of uniquely shared haplotypes with diverse localities combined with the trade data suggested multiple incursions and introduction origins in Brazil. Increasing agricultural/horticultural trade activities between the Old and New Worlds represents a significant biosecurity risk factor. Identifying pest origins will enable resistance profiling that reflects countries of origin to be included when developing a resistance management strategy, while identifying incursion pathways will improve biosecurity protocols and risk analysis at biosecurity hotspots including national portsESC and IBM were supported by CSIRO Health and Biosecurity, the Brazilian Government’s, Science without Boarders (Ciência sem Fronteiras) summer internship program (242166/2012–1 (ESC); 209297/2013-1 (IBM)), and Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) scholarships. CA was supported by a CSIRO OCE Post Doctoral Fellowship (R-03255-01). WTT and TKW acknowledged funing support from CSIRO Health & Biosecurity ‘Genes of Biosecurity Significance’ (R-8681-1). CC acknowledges funding support from FAPEG (Fundação de amparo a pesquisa do estado de Goiás) (Grant number: Helicoverpa/2013102670001419)
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