49 research outputs found

    The role of endothelial dysfunction for pregnancy complications occurrence with asiderotic anemia in pregnant women

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    The aim of the study was to assess the endothelium in pregnant women suffering from iron deficiency anemia . It is shown that the combination of IDA and placental dysfunction is associated with the signs of endothelial dysfunction in the form of asymmetric response of endothelium to reactive hyperemia after mechanical stress on the vascular wall and increase the diameter of the brachial artery by more than 10 % in 85 % of pregnant women. The data suggest that the assessment of the functional state of the endothelium via flow-dependent vasodilation is adequate non-invasive method of assessing the nature of endothelial function in pregnant women

    ΠžΠ±Π΅ΡΠΏΠ΅Ρ‡Π΅Π½ΠΈΠ΅ качСства мСдицинского образования Π² Π°ΠΊΡƒΡˆΠ΅Ρ€ΡΡ‚Π²Π΅ ΠΈ Π³ΠΈΠ½Π΅ΠΊΠΎΠ»ΠΎΠ³ΠΈΠΈ

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    This study was aimed to determine the perspectives of the quality assurance systems in education process for obstetrics and gynecology. The experience of assurence of quality performance and care in the medical education was analysed. There was shown that quality assurance in teaching obstetrics and gynecology helps to promote good academic performance and increase competiveness of medical students.ЦСлью исслСдования Π±Ρ‹Π»ΠΎ ΠΎΠΏΡ€Π΅Π΄Π΅Π»ΠΈΡ‚ΡŒ пСрспСктивы развития систСм обСспСчСния качСства Π² процСссС прСподавания Π°ΠΊΡƒΡˆΠ΅Ρ€ΡΡ‚Π²Π° ΠΈ Π³ΠΈΠ½Π΅ΠΊΠΎΠ»ΠΎΠ³ΠΈΠΈ. Показано Ρ‡Ρ‚ΠΎ использованиС систСм обСспСчСния качСства прСподавания позволяСт ΡƒΠ»ΡƒΡ‡ΡˆΠΈΡ‚ΡŒ Π°ΠΊΠ°Π΄Π΅ΠΌΠΈΡ‡Π΅ΡΠΊΡƒΡŽ ΡƒΡΠΏΠ΅Π²Π°Π΅ΠΌΠΎΡΡ‚ΡŒ ΠΈ ΠΏΠΎΠ²Ρ‹ΡΠΈΡ‚ΡŒ ΠΏΡ€ΠΎΡ„Π΅ΡΡΠΈΠΎΠ½Π°Π»ΡŒΠ½Ρ‹ΠΉ ΡƒΡ€ΠΎΠ²Π΅Π½ΡŒ студСнтов мСдицинского Π’Π£Π—Π°

    The role of modern information resources in the teaching of foreign students of medical university

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    Ancheva I. A. The role of modern information resources in the teaching of foreign students of medical university. Journal of Education, Health and Sport. 2017;7(1):284-292. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.260173http://ojs.ukw.edu.pl/index.php/johs/article/view/4197Β Β Β Β The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part B item 754 (09.12.2016).754 Journal of Education, Health and Sport eISSN 2391-8306 7Β© The Author (s) 2017;This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, PolandOpen Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License(http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited.This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited.The authors declare that there is no conflict of interests regarding the publication of this paper.Received: 02.01.2017. Revised 16.01.2017. Accepted: 24.01.2017.Β UDK 61: 378.147 : 004]-054.6Β THE ROLE OF MODERN INFORMATION RESOURCES IN THE TEACHING OF FOREIGN STUDENTS OF MEDICAL UNIVERSITYΒ I. A. Ancheva Β Odessa National Medical University, Ukraine, [email protected]Β SummaryEnsuring a high level of clinical training of medical students in higher institutions and improving the quality of teaching remain the most important aims.The purpose of study was examination of the most frequently used sources of information in obstetrics and gynecology, resorted to by English-speaking students during self-study based on a large volume of available information. The materials were the results of the foreign students` survey.The article has described and analyzed modern and optimal forms of teaching the discipline of obstetrics and gynecology to foreign students of the medical university, taking into account the possible use of different information resources.Keywords: information resources and technologies, mobile applications, the system of higher medical education, English-speaking students

    Role of modern virtual simulators for vocational training of medical professions

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    Π’ΠΈΠ·Π½Π°Ρ‡Π΅Π½Π° Ρ€ΠΎΠ»ΡŒ Ρ– Π½Π΅ΠΎΠ±Ρ…Ρ–Π΄Π½Ρ–ΡΡ‚ΡŒ Ρƒ використанні сучасних Π²Ρ–Ρ€Ρ‚ΡƒΠ°Π»ΡŒΠ½ΠΈΡ… симуляторів, Ρ‰ΠΎ Π·Π°Π±Π΅Π·ΠΏΠ΅Ρ‡ΡƒΡŽΡ‚ΡŒ створСння Ρ€Π΅Π°Π»ΡŒΠ½ΠΎΡΡ‚Ρ– ΠΌΠ΅Π΄ΠΈΡ‡Π½ΠΈΡ… Π²Ρ‚Ρ€ΡƒΡ‡Π°Π½ΡŒ Ρ– ΠΏΡ€ΠΎΡ†Π΅Π΄ΡƒΡ€, Π² курсі освоєння ΠΊΠ»Ρ–Π½Ρ–Ρ‡Π½ΠΈΡ… дисциплін Ρ– для вдосконалСння ΠΏΡ€Π°ΠΊΡ‚ΠΈΡ‡Π½ΠΈΡ… Π½Π°Π²ΠΈΠΊΡ–Π². На ΡΡŒΠΎΠ³ΠΎΠ΄Π½Ρ– Ρ€ΠΎΠ±ΠΎΡ‚Π° Π½Π° Ρ„Π°Π½Ρ‚ΠΎΠΌΠ°Ρ… Ρ” ΠΏΠ΅Ρ€Π΅Ρ…Ρ–Π΄Π½ΠΈΠΌ Ρ€Ρ–Π²Π½Π΅ΠΌ Π²Ρ–Π΄ Ρ‚Π΅ΠΎΡ€Ρ–Ρ— Π΄ΠΎ ΠΏΡ€Π°ΠΊΡ‚ΠΈΡ‡Π½ΠΎΡ— Π΄Ρ–ΡΠ»ΡŒΠ½ΠΎΡΡ‚Ρ– лікаря.Theris determine the role and the necessity to use modern virtual simulators that provide a reality of medical interventions and procedures in the course of development of clinical disciplines and improve practical skills. In the modern day work on phantoms is a training on the phantoms is transitional level for the movement from theory tomedical practice

    Functional food in pregnancy

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    Π’ ΠΎΠ±Π·ΠΎΡ€Π΅ ΠΏΡ€ΠΎΠ²Π΅Π΄Π΅Π½ Π°Π½Π°Π»ΠΈΠ· соврСмСнного состояния ΠΏΡ€ΠΎΠ±Π»Π΅ΠΌΡ‹ примСнСния Ρ„ΡƒΠ½ΠΊΡ†ΠΈΠΎΠ½Π°Π»ΡŒΠ½Ρ‹Ρ… ΠΏΠΈΡ‰Π΅Π²Ρ‹Ρ… ΠΏΡ€ΠΎΠ΄ΡƒΠΊΡ‚ΠΎΠ² ΠΏΡ€ΠΈ Π²Π΅Π΄Π΅Π½ΠΈΠΈ Π±Π΅Ρ€Π΅ΠΌΠ΅Π½Π½Ρ‹Ρ… с Π°Π»ΠΈΠΌΠ΅Π½Ρ‚Π°Ρ€Π½Ρ‹ΠΌ Π΄Π΅Ρ„ΠΈΡ†ΠΈΡ‚ΠΎΠΌ ΡΡΡΠ΅Π½Ρ†ΠΈΠ°Π»ΡŒΠ½Ρ‹Ρ… Π½ΡƒΡ‚Ρ€ΠΈΠ΅Π½Ρ‚ΠΎΠ². Π Π°ΡΡΠΌΠ°Ρ‚Ρ€ΠΈΠ²Π°ΡŽΡ‚ΡΡ клиничСскиС эффСкты ΠΎΡ‚ примСнСния Ρ€Π°Π·Π»ΠΈΡ‡Π½Ρ‹Ρ… ΠΏΡ€ΠΎΠ΄ΡƒΠΊΡ‚ΠΎΠ² Ρ„ΡƒΠ½ΠΊΡ†ΠΈΠΎΠ½Π°Π»ΡŒΠ½ΠΎΠ³ΠΎ питания. ΠŸΡ€ΠΈΠ²Π΅Π΄Π΅Π½Ρ‹ ΠΏΡ€ΠΈΠΌΠ΅Ρ€Ρ‹ Π°Π΄Π΄ΠΈΡ‚ΠΈΠ²Π½ΠΎΠ³ΠΎ взаимодСйствия Π½ΡƒΡ‚Ρ€ΠΈΠ΅Π½Ρ‚ΠΎΠ² ΠΏΡ€ΠΈ ΠΎΠ±ΠΎΠ³Π°Ρ‰Π΅Π½ΠΈΠΈ ΠΈΠΌΠΈ Ρ‚Ρ€Π°Π΄ΠΈΡ†ΠΈΠΎΠ½Π½Ρ‹Ρ… ΠΏΠΈΡ‰Π΅Π²Ρ‹Ρ… ΠΏΡ€ΠΎΠ΄ΡƒΠΊΡ‚ΠΎΠ². Π Π°ΡΡΠΌΠ°Ρ‚Ρ€ΠΈΠ²Π°ΡŽΡ‚ΡΡ вопросы ΠΌΠ΅Ρ‚ΠΎΠ΄ΠΎΠ»ΠΎΠ³ΠΈΠΈ Π²Ρ‹Π±ΠΎΡ€Π° ΠΏΡ€ΠΎΠ΄ΡƒΠΊΡ‚ΠΎΠ² для нутрициологичСской ΠΊΠΎΡ€Ρ€Π΅ΠΊΡ†ΠΈΠΈ. АнализируСтся ΠΌΠ΅ΠΆΠ΄ΡƒΠ½Π°Ρ€ΠΎΠ΄Π½Ρ‹ΠΉ ΠΎΠΏΡ‹Ρ‚ Ρ€Π°Π·Ρ€Π°Π±ΠΎΡ‚ΠΊΠΈ Ρ„ΠΎΡ€Ρ‚ΠΈΡ„ΠΈΠΊΠ°Ρ†ΠΈΠΎΠ½Π½Ρ‹Ρ… схСм для Π±Π°Π·ΠΎΠ²Ρ‹Ρ… ΠΏΠΈΡ‰Π΅Π²Ρ‹Ρ… ΠΏΡ€ΠΎΠ΄ΡƒΠΊΡ‚ΠΎΠ². ОсобоС Π²Π½ΠΈΠΌΠ°Π½ΠΈΠ΅ ΡƒΠ΄Π΅Π»Π΅Π½ΠΎ ΠΏΡ€ΠΎΠ±Π»Π΅ΠΌΠ΅ ΠΆΠ΅Π»Π΅Π·ΠΎΠ΄Π΅Ρ„ΠΈΡ†ΠΈΡ‚Π° Ρƒ Π±Π΅Ρ€Π΅ΠΌΠ΅Π½Π½Ρ‹Ρ…. ΠΠΊΡ†Π΅Π½Ρ‚ΠΈΡ€ΡƒΡŽΡ‚ΡΡ вопросы клиничСской эпидСмиологии ΠΆΠ΅Π»Π΅Π·ΠΎΠ΄Π΅Ρ„ΠΈΡ†ΠΈΡ‚Π½Ρ‹Ρ… состояний Ρƒ ΠΆΠ΅Π½Ρ‰ΠΈΠ½ Ρ„Π΅Ρ€Ρ‚ΠΈΠ»ΡŒΠ½ΠΎΠ³ΠΎ возраста, ΠΏΠ°Ρ‚ΠΎΡ„ΠΈΠ·ΠΈΠΎΠ»ΠΎΠ³ΠΈΠΈ сидСропСничСского синдрома, связи Π΅Π³ΠΎ с Π΄Ρ€ΡƒΠ³ΠΈΠΌΠΈ нозологичСскими Π΅Π΄ΠΈΠ½ΠΈΡ†Π°ΠΌΠΈ. Показано, Ρ‡Ρ‚ΠΎ коррСкция Π΄Π΅Ρ„ΠΈΡ†ΠΈΡ‚Π° ΠΆΠ΅Π»Π΅Π·Π° Ρƒ Π±Π΅Ρ€Π΅ΠΌΠ΅Π½Π½Ρ‹Ρ… с ΠΆΠ΅Π»Π΅Π·ΠΎΠ΄Π΅Ρ„ΠΈΡ†ΠΈΡ‚Π½ΠΎΠΉ Π°Π½Π΅ΠΌΠΈΠ΅ΠΉ Π΄ΠΎΠ»ΠΆΠ½Π° ΠΏΡ€ΠΎΠ²ΠΎΠ΄ΠΈΡ‚ΡŒΡΡ Π΄ΠΈΡ„Ρ„Π΅Ρ€Π΅Π½Ρ†ΠΈΡ€ΠΎΠ²Π°Π½Π½ΠΎ Π² зависимости ΠΎΡ‚ стСпСни тяТСсти Π°Π½Π΅ΠΌΠΈΠΈ. ΠŸΡ€ΠΈ ΠΆΠ΅Π»Π΅Π·ΠΎΠ΄Π΅Ρ„ΠΈΡ†ΠΈΡ‚Π½ΠΎΠΉ Π°Π½Π΅ΠΌΠΈΠΈ Π»Π΅Π³ΠΊΠΎΠΉ стСпСни проводят Π°Π»ΠΈΠΌΠ΅Π½Ρ‚Π°Ρ€Π½ΡƒΡŽ ΠΊΠΎΡ€Ρ€Π΅ΠΊΡ†ΠΈΡŽ потрСблСния ΠΆΠ΅Π»Π΅Π·Π° с ΠΏΠΎΠΌΠΎΡ‰ΡŒΡŽ Π²ΠΈΡ‚Π°ΠΌΠΈΠ½Π½ΠΎ-ΠΌΠΈΠ½Π΅Ρ€Π°Π»ΡŒΠ½Ρ‹Ρ… комплСксов с содСрТаниСм органичСских солСй Π΄Π²ΡƒΡ…Π²Π°Π»Π΅Π½Ρ‚Π½ΠΎΠ³ΠΎ ΠΆΠ΅Π»Π΅Π·Π° Π½Π΅ ΠΌΠ΅Π½Π΅Π΅ 60 ΠΌΠ³ ΠΈ Π΄Ρ€ΡƒΠ³ΠΈΡ… антианСмичСских биологичСски Π°ΠΊΡ‚ΠΈΠ²Π½Ρ‹Ρ… Π½ΡƒΡ‚Ρ€ΠΈΠ΅Π½Ρ‚ΠΎΠ² Π² физиологичСских для бСрСмСнности Π΄ΠΎΠ·ΠΈΡ€ΠΎΠ²ΠΊΠ°Ρ…. ΠžΠ±ΡΡƒΠΆΠ΄Π°ΡŽΡ‚ΡΡ ΠΏΡ€ΠΎΠ±Π»Π΅ΠΌΡ‹ использования ΠΏΡ€ΠΎΠ΄ΡƒΠΊΡ‚ΠΎΠ², ΠΎΠ±ΠΎΠ³Π°Ρ‰Π΅Π½Π½Ρ‹Ρ… ΠΏΡ€ΠΎΠ±ΠΈΠΎΡ‚ΠΈΠΊΠ°ΠΌΠΈ, ΠΏΠΈΡ‰Π΅Π²Ρ‹ΠΌΠΈ Π²ΠΎΠ»ΠΎΠΊΠ½Π°ΠΌΠΈ, ΠΊΠ°Π»ΡŒΡ†ΠΈΠ΅ΠΌ, Ρ„Ρ‚ΠΎΡ€ΠΎΠΌ, ΠΉΠΎΠ΄ΠΎΠΌ ΠΈ ΠΏΡ€Π΅Π±ΠΈΠΎΡ‚ΠΈΠΊΠ°ΠΌΠΈ. Π Π°ΡΡΠΌΠ°Ρ‚Ρ€ΠΈΠ²Π°ΡŽΡ‚ΡΡ вопросы бСзопасности примСнСния ΠΏΡ€ΠΎΠ΄ΡƒΠΊΡ‚ΠΎΠ² Ρ„ΡƒΠ½ΠΊΡ†ΠΈΠΎΠ½Π°Π»ΡŒΠ½ΠΎΠ³ΠΎ питания Ρƒ Π±Π΅Ρ€Π΅ΠΌΠ΅Π½Π½Ρ‹Ρ…. ΠžΡ‚ΠΌΠ΅Ρ‡Π°Π΅Ρ‚ΡΡ, Ρ‡Ρ‚ΠΎ практичСскоС ΠΏΡ€ΠΈΠΌΠ΅Π½Π΅Π½ΠΈΠ΅ ΠΏΠΎΠ»ΠΎΠΆΠ΅Π½ΠΈΠΉ ΠΊΠΎΠ½Ρ†Π΅ΠΏΡ†ΠΈΠΈ Ρ„ΡƒΠ½ΠΊΡ†ΠΈΠΎΠ½Π°Π»ΡŒΠ½ΠΎΠ³ΠΎ питания позволяСт ΡΠΊΠΎΡ€Ρ€Π΅ΠΊΡ‚ΠΈΡ€ΠΎΠ²Π°Ρ‚ΡŒ ΠΈΠΌΠ΅ΡŽΡ‰ΠΈΠΉΡΡ Π°Π»ΠΈΠΌΠ΅Π½Ρ‚Π°Ρ€Π½Ρ‹ΠΉ Π΄Π΅Ρ„ΠΈΡ†ΠΈΡ‚ начиная с Ρ€Π°Π½Π½ΠΈΡ… сроков бСрСмСнности ΠΈ Π·Π½Π°Ρ‡ΠΈΡ‚Π΅Π»ΡŒΠ½ΠΎ ΡΠ½ΠΈΠ·ΠΈΡ‚ΡŒ риск ослоТнСний бСрСмСнности ΠΈ Ρ€ΠΎΠ΄ΠΎΠ². Π’Ρ‹Π±ΠΎΡ€ ΠΎΠΏΡ‚ΠΈΠΌΠ°Π»ΡŒΠ½Ρ‹Ρ… стратСгий нутрициологичСской ΠΊΠΎΡ€Ρ€Π΅ΠΊΡ†ΠΈΠΈ зависит ΠΎΡ‚ клиничСской эпидСмиологии Π°Π»ΠΈΠΌΠ΅Π½Ρ‚Π°Ρ€Π½ΠΎΠ³ΠΎ Π΄Π΅Ρ„ΠΈΡ†ΠΈΡ‚Π° ΠΈ ΠΌΠΎΠΆΠ΅Ρ‚ ΠΎΡΡƒΡ‰Π΅ΡΡ‚Π²Π»ΡΡ‚ΡŒΡΡ ΠΊΠ°ΠΊ Π½Π° ΠΈΠ½Π΄ΠΈΠ²ΠΈΠ΄ΡƒΠ°Π»ΡŒΠ½ΠΎΠΌ, Ρ‚Π°ΠΊ ΠΈ Π½Π° популяционном ΡƒΡ€ΠΎΠ²Π½Π΅.The current state of the functional food usage in clinical guidance of pregnant females with the alimentary deficiency of essential nutrients was conducted in the review. The clinical effects of the use of various functional food products were discussed. The instances of the additive interaction of nutrients used for food fortification were depicted. The issues of the methodology of selecting food products for the diet correction were reviewed. The international experience of the development of fortification schemes for basic food products was analyzed. The especial attention was dedicated to the problem of iron deficiency in pregnant females. There were urged the issues of clinical epidemiology of iron deficiency states amongst females of fertile age, the pathophysiology of sideropenic syndrome, its associations with other nosologies. There was demonstrated that the correction of iron deficiency amongst pregnant females suffering from iron deficiency anemia should be differentiated accordingly to the anemia severity. For mild severity of iron deficiency the diet correction of iron consumption should be conducted with the administration of vitamin-mineral complexes containing not less than 60 mg organic salts of bivalent iron and other antianemic biologically active nutrients in the physiological dosages for pregnancy. The issues of the usage of food fortified with probiotics, food fiber, calcium, iodine and prebiotics were discussed. There were conversed the safety issues of the usage of functional food in pregnant females. There was argued that the practical application of the concept of functional food could be helpful for the correction of the present alimentary deficiency since early terms of gestation as well as reduce the risk of pregnancy and childbirth complications significantly. The selection of the optimal strategies of diet correction depends on the clinical epidemiology of alimentary deficiency and could be realized at the individual as well as at the population level

    Comprehensive preconception preparation in women with iron deficiency

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    ЦСлью Ρ€Π°Π±ΠΎΡ‚Ρ‹ Π±Ρ‹Π»Π° ΠΎΡ†Π΅Π½ΠΊΠ° клиничСской эффСктивности ΠΏΡ€Π΅Π³Ρ€Π°Π²ΠΈΠ΄Π°Ρ€Π½ΠΎΠΉ ΠΈ ΠΏΠ΅Ρ€ΠΈΠΊΠΎΠ½Ρ†Π΅ΠΏΡ†ΠΈΠΎΠ½Π½ΠΎΠΉ ΠΏΠΎΠ΄Π³ΠΎΡ‚ΠΎΠ²ΠΊΠΈ ΠΆΠ΅Π½Ρ‰ΠΈΠ½, ΠΈΠΌΠ΅ΡŽΡ‰ΠΈΡ… Π² Π°Π½Π°ΠΌΠ½Π΅Π·Π΅ указания Π½Π° пСрСнСсСнныС ΠΆΠ΅Π»Π΅Π·ΠΎΠ΄Π΅Ρ„ΠΈΡ†ΠΈΡ‚Π½Ρ‹Π΅ состояния. ΠŸΡ€Π΅Π΄Π»ΠΎΠΆΠ΅Π½Π° комплСксная прСгравидарная ΠΏΠΎΠ΄Π³ΠΎΡ‚ΠΎΠ²ΠΊΠ°, Π²ΠΊΠ»ΡŽΡ‡Π°ΡŽΡ‰Π°Ρ патогСнСтичСскиС срСдства ΠΏΠΎ ΠΊΠΎΡ€Ρ€Π΅ΠΊΡ†ΠΈΠΈ Ρ„Π°ΠΊΡ‚ΠΎΡ€ΠΎΠ² риска ΠΆΠ΅Π»Π΅Π·ΠΎΠ΄Π΅Ρ„ΠΈΡ†ΠΈΡ‚Π½Ρ‹Ρ… состояний, которая позволяСт Π½ΠΎΡ€ΠΌΠ°Π»ΠΈΠ·ΠΎΠ²Π°Ρ‚ΡŒ гСматологичСскиС ΠΈ фСррокинСтичСскиС ΠΏΠΎΠΊΠ°Π·Π°Ρ‚Π΅Π»ΠΈ Π΄ΠΎ ΠΏΠ»Π°Π½ΠΈΡ€ΡƒΠ΅ΠΌΠΎΠ³ΠΎ ΠΌΠΎΠΌΠ΅Π½Ρ‚Π° зачатия. УстановлСно достовСрноС ΡƒΠΌΠ΅Π½ΡŒΡˆΠ΅Π½ΠΈΠ΅ частоты развития ослоТнСний бСрСмСнности ΠΈ Ρ€ΠΎΠ΄ΠΎΠ² Ρƒ ΠΆΠ΅Π½Ρ‰ΠΈΠ½ с ΠΆΠ΅Π»Π΅Π·ΠΎΠ΄Π΅Ρ„ΠΈΡ†ΠΈΡ‚Π½ΠΎΠΉ Π°Π½Π΅ΠΌΠΈΠ΅ΠΉ ΠΏΡ€ΠΈ ΠΏΡ€ΠΎΠ²Π΅Π΄Π΅Π½ΠΈΠΈ комплСксной ΠΏΡ€Π΅Π³Ρ€Π°Π²ΠΈΠ΄Π°Ρ€Π½ΠΎΠΉ ΠΏΠΎΠ΄Π³ΠΎΡ‚ΠΎΠ²ΠΊΠΈ.The aim of this study was to evaluate the clinical effcacy of preconception preparation in women with a history of iron defciency. The complex preconception preparation with pathogenic drugs for the correction of the main risk factors of iron defciency allowed normalizing the hematological and ferrokinetic parameters before the planned moment of conception. There was determined a signifcant reduction in the incidence of pregnancy and delivery complications in women with iron defciency anemia when making a complex preconception preparation

    НСкоторыС характСристики личности ΠΆΠ΅Π½Ρ‰ΠΈΠ½, ΠΈΠ·Π±Ρ€Π°Π²ΡˆΠΈΡ… Ρ€Π°Π·Π»ΠΈΡ‡Π½Ρ‹Π΅ ΠΌΠ΅Ρ‚ΠΎΠ΄Ρ‹ обСзболивания Ρ€ΠΎΠ΄ΠΎΠ²

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    Π’ΠΈΠ·Π½Π°Ρ‡Π΅Π½ΠΎ психологічний Ρ‚ΠΈΠΏ Ρ– ΡΡ‚ΡƒΠΏΡ–Π½ΡŒ Π΅ΠΌΠΎΡ†Ρ–ΠΉΠ½ΠΎΡ— стійкості-нСстійкості Ρƒ 160 ΠΆΡ–Π½ΠΎΠΊ, Ρ‰ΠΎ ΠΎΠ±Ρ€Π°Π»ΠΈ Ρ€Ρ–Π·Π½Ρ– Π²ΠΈΠ΄ΠΈ знСболювання ΠΏΠΎΠ»ΠΎΠ³Ρ–Π². ΠœΠ΅Ρ‚ΠΎΠ΄ знСболювання ΠΏΠ°Ρ†Ρ–Ρ”Π½Ρ‚ΠΊΠΈ ΠΎΠ±ΠΈΡ€Π°Π»ΠΈ самостійно після одСрТання Π½ΠΈΠΌΠΈ ΠΏΠΎΠ²Π½ΠΎΡ— Ρ–Π½Ρ„ΠΎΡ€ΠΌΠ°Ρ†Ρ–Ρ—. Усі ΠΆΡ–Π½ΠΊΠΈ ΠΏΡ€ΠΎΠΉΡˆΠ»ΠΈ Ρ‚Ρ€Π°Π΄ΠΈΡ†Ρ–ΠΉΠ½Ρ– курси психопрофілактичної ΠΏΡ–Π΄Π³ΠΎΡ‚ΠΎΠ²ΠΊΠΈ Π΄ΠΎ ΠΏΠΎΠ»ΠΎΠ³Ρ–Π² Π½Π° Π΅Ρ‚Π°ΠΏΡ– ΠΆΡ–Π½ΠΎΡ‡ΠΎΡ— ΠΊΠΎΠ½ΡΡƒΠ»ΡŒΡ‚Π°Ρ†Ρ–Ρ—. ΠŸΡ€ΠΎΠ°Π½Π°Π»Ρ–Π·ΠΎΠ²Π°Π½ΠΎ Π²ΠΈΠ±Ρ–Ρ€ ΠΌΠ΅Ρ‚ΠΎΠ΄Ρ–Π² знСболювання ΠΏΠΎΠ»ΠΎΠ³Ρ–Π² ΠΆΡ–Π½ΠΊΠ°ΠΌΠΈ Π· Ρ€Ρ–Π·Π½ΠΈΠΌΠΈ Ρ–Π½Π΄ΠΈΠ²Ρ–Π΄ΡƒΠ°Π»ΡŒΠ½ΠΎ-психологічними характСристиками. ΠŸΠ°Ρ†Ρ–Ρ”Π½Ρ‚ΠΊΠΈ Ρ€Ρ–Π·Π½ΠΈΡ… психотипів ΠΎΠ±ΠΈΡ€Π°Π»ΠΈ Ρ€Ρ–Π·Π½Ρ– ΠΌΠ΅Ρ‚ΠΎΠ΄ΠΈ знСболювання ΠΏΠΎΠ»ΠΎΠ³Ρ–Π². ΠžΡ‚Ρ€ΠΈΠΌΠ°Π½Ρ– Π΄Π°Π½Ρ– Π΄ΠΎΠ·Π²ΠΎΠ»ΠΈΠ»ΠΈ Π·Ρ€ΠΎΠ±ΠΈΡ‚ΠΈ висновки ΠΏΡ€ΠΎ Ρ‚Π΅, Ρ‰ΠΎ Ρ–Π½Π΄ΠΈΠ²Ρ–Π΄ΡƒΠ°Π»ΡŒΠ½ΠΎΠΎΡΠΎΠ±ΠΈΡΡ‚Ρ–ΡΠ½Ρ– характСристики ΠΆΡ–Π½ΠΎΠΊ ΠΎΠ±ΡƒΠΌΠΎΠ²Π»ΡŽΡŽΡ‚ΡŒ Ρ—Ρ…Π½Ρ” Π²Ρ–Π΄Π½ΠΎΡˆΠ΅Π½Π½Ρ Π΄ΠΎ знСболювання ΠΏΠΎΠ»ΠΎΠ³Ρ–Π² Ρ– Π²ΠΈΠ±ΠΎΡ€Ρƒ ΠΌΠ΅Ρ‚ΠΎΠ΄Π£ знСболювання Π·Π° ΡƒΠΌΠΎΠ²ΠΈ ΠΏΠΎΠ²Π½ΠΎΡ— інформованості ΠΏΠ°Ρ†Ρ–Ρ”Π½Ρ‚ΠΊΠΈ.Psychological type and degree of emotional stability-instability of 160 women who have chosen different methods of delivery anesthesia were different. Method of delivery anesthesia was chosen by the patients without assistance after obtaining the detailed information. All the patients attended traditional psychoprophylaxis delivery training during their maternity consultations. The choice of delivery anesthesia methods by women with different individual psychotypological characteristics was analysed. Patients having different psychotypes preferred different delivery anesthesia methods. Data obtained allowed to come to conclusion that mainly individual and personal peculiarities of women determine their attitude towards delivery anesthesia and chosing the delivery anesthesia method if patient is informed in detail.ΠžΠΏΡ€Π΅Π΄Π΅Π»Π΅Π½Ρ‹ психологичСскиС Ρ‚ΠΈΠΏΡ‹ ΠΈ ΡΡ‚Π΅ΠΏΠ΅Π½ΡŒ ΡΠΌΠΎΡ†ΠΈΠΎΠ½Π°Π»ΡŒΠ½ΠΎΠΉ устойчивости-нСустойчивости Ρƒ 160 ΠΆΠ΅Π½Ρ‰ΠΈΠ½, ΠΈΠ·Π±Ρ€Π°Π²ΡˆΠΈΡ… Ρ€Π°Π·Π»ΠΈΡ‡Π½Ρ‹Π΅ Π²ΠΈΠ΄Ρ‹ обСзболивания Ρ€ΠΎΠ΄ΠΎΠ². ΠœΠ΅Ρ‚ΠΎΠ΄ обСзболивания ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΊΠΈ ΠΈΠ·Π±ΠΈΡ€Π°Π»ΠΈ ΡΠ°ΠΌΠΎΡΡ‚ΠΎΡΡ‚Π΅Π»ΡŒΠ½ΠΎ послС получСния ΠΈΠΌΠΈ ΠΏΠΎΠ»Π½ΠΎΠΉ ΠΈΠ½Ρ„ΠΎΡ€ΠΌΠ°Ρ†ΠΈΠΈ. ВсС ΠΆΠ΅Π½Ρ‰ΠΈΠ½Ρ‹ ΠΏΡ€ΠΎΡˆΠ»ΠΈ Ρ‚Ρ€Π°Π΄ΠΈΡ†ΠΈΠΎΠ½Π½Ρ‹Π΅ курсы психопрофилактичСской ΠΏΠΎΠ΄Π³ΠΎΡ‚ΠΎΠ²ΠΊΠΈ ΠΊ Ρ€ΠΎΠ΄Π°ΠΌ Π½Π° этапС ТСнской ΠΊΠΎΠ½ΡΡƒΠ»ΡŒΡ‚Π°Ρ†ΠΈΠΈ. ΠŸΡ€ΠΎΠ°Π½Π°Π»ΠΈΠ·ΠΈΡ€ΠΎΠ²Π°Π½ Π²Ρ‹Π±ΠΎΡ€ ΠΌΠ΅Ρ‚ΠΎΠ΄Π° обСзболивания Ρ€ΠΎΠ΄ΠΎΠ² ΠΆΠ΅Π½Ρ‰ΠΈΠ½Π°ΠΌΠΈ с Ρ€Π°Π·Π»ΠΈΡ‡Π½Ρ‹ΠΌΠΈ ΠΈΠ½Π΄ΠΈΠ²ΠΈΠ΄ΡƒΠ°Π»ΡŒΠ½ΠΎ-психологичСскими характСристиками. ΠŸΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΊΠΈ Ρ€Π°Π·Π»ΠΈΡ‡Π½Ρ‹Ρ… психотипов, ΠΏΡ€Π΅Π΄ΠΏΠΎΡ‡ΠΈΡ‚Π°Π»ΠΈ Ρ€Π°Π·Π½Ρ‹Π΅ ΠΌΠ΅Ρ‚ΠΎΠ΄Ρ‹ обСзболивания Ρ€ΠΎΠ΄ΠΎΠ². ΠŸΠΎΠ»ΡƒΡ‡Π΅Π½Π½Ρ‹Π΅ Π΄Π°Π½Π½Ρ‹Π΅ ΠΏΠΎΠ·Π²ΠΎΠ»ΠΈΠ»ΠΈ ΡΠ΄Π΅Π»Π°Ρ‚ΡŒ Π²Ρ‹Π²ΠΎΠ΄Ρ‹ ΠΎ Ρ‚ΠΎΠΌ, Ρ‡Ρ‚ΠΎ ΠΈΠ½Π΄ΠΈΠ²ΠΈΠ΄ΡƒΠ°Π»ΡŒΠ½ΠΎ-личностныС особСнности ΠΆΠ΅Π½Ρ‰ΠΈΠ½ Π²ΠΎ ΠΌΠ½ΠΎΠ³ΠΎΠΌ ΠΎΠ±ΡƒΡΠ»ΠΎΠ²Π»ΠΈΠ²Π°ΡŽΡ‚ ΠΈΡ… ΠΎΡ‚Π½ΠΎΡˆΠ΅Π½ΠΈΠ΅ ΠΊ обСзболиванию Ρ€ΠΎΠ΄ΠΎΠ² ΠΈ Π²Ρ‹Π±ΠΎΡ€ ΠΌΠ΅Ρ‚ΠΎΠ΄Π° обСзболивания ΠΏΡ€ΠΈ условии ΠΏΠΎΠ»Π½ΠΎΠΉ информированности ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΊΠΈ

    Π˜ΠΌΠΌΡƒΠ½ΠΎΠ³ΠΈΡΡ‚ΠΎΡ…ΠΈΠΌΠΈΡ‡Π΅ΡΠΊΠΈΠ΅ особСнности экспрСссии ΡΠ½Π΄ΠΎΡ‚Π΅Π»ΠΈΠ°Π»ΡŒΠ½ΠΎΠΉ нитроксидсинтазы Π² ΠΏΠ»Π°Ρ†Π΅Π½Ρ‚Π΅ ΠΏΡ€ΠΈ Π΅Π΅ дисфункции Ρƒ ΠΆΠ΅Π½Ρ‰ΠΈΠ½ Π½Π° Ρ„ΠΎΠ½Π΅ ΠΆΠ΅Π»Π΅Π·ΠΎΠ΄Π΅Ρ„ΠΈΡ†ΠΈΡ‚Π½ΠΎΠΉ Π°Π½Π΅ΠΌΠΈΠΈ

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    ΠΠΊΡ‚ΡƒΠ°Π»ΡŒΠ½Ρ–ΡΡ‚ΡŒ дослідТСння Π·ΡƒΠΌΠΎΠ²Π»Π΅Π½Π° Π·Π½Π°Ρ‡Π½ΠΎΡŽ ΠΏΠΎΡˆΠΈΡ€Π΅Π½Ρ–ΡΡ‚ΡŽ дисфункції ΠΏΠ»Π°Ρ†Π΅Π½Ρ‚ΠΈ Ρƒ Π²Π°Π³Ρ–Ρ‚Π½ΠΈΡ…, які Ρ…Π²ΠΎΡ€Ρ– Π½Π° Π°Π½Π΅ΠΌΡ–ΡŽ. Π— ΠΌΠ΅Ρ‚ΠΎΡŽ ΠΎΡ†Ρ–Π½ΡŽΠ²Π°Π½Π½Ρ імуногістохімічних особливостСй СкспрСсії Π΅Π½Π΄ΠΎΡ‚Π΅Π»Ρ–Π°Π»ΡŒΠ½ΠΎΡ— NO-синтази (eNOS) Ρƒ ΠΏΠ»Π°Ρ†Π΅Π½Ρ‚Ρ– ΠΏΡ€ΠΈ Ρ—Ρ— дисфункції Ρƒ ΠΆΡ–Π½ΠΎΠΊ Π½Π° Ρ‚Π»Ρ– Π°Π½Π΅ΠΌΡ–Ρ— дослідили 30 Π·Ρ€Π°Π·ΠΊΡ–Π² ΠΏΠ»Π°Ρ†Π΅Π½Ρ‚Π°Ρ€Π½ΠΎΡ— Ρ‚ΠΊΠ°Π½ΠΈΠ½ΠΈ Ρ–Π· застосуванням імуногістохімічного Ρ‚Π° ΠΌΡ–ΠΊΡ€ΠΎΠΌΠ΅Ρ‚Ρ€ΠΈΡ‡Π½ΠΎΠ³ΠΎ ΠΌΠ΅Ρ‚ΠΎΠ΄Ρ–Π². ВстановлСно, Ρ‰ΠΎ СкспрСсія Π΅NOS Ρƒ ΠΏΠ°Ρ†Ρ–Ρ”Π½Ρ‚ΠΎΠΊ Ρ–Π· Π·Π°Π»Ρ–Π·ΠΎΠ΄Π΅Ρ„Ρ–Ρ†ΠΈΡ‚Π½ΠΎΡŽ Π°Π½Π΅ΠΌΡ–Ρ”ΡŽ Π² Ρ†ΠΈΡ‚ΠΎΠΏΠ»Π°Π·ΠΌΡ– ΡΠΈΠ½Ρ†ΠΈΡ‚Ρ–ΡŽ ворсинок Ρ– Π΅Π½Π΄ΠΎΡ‚Π΅Π»Ρ–ΡŽ Ρ„Π΅Ρ‚Π°Π»ΡŒΠ½ΠΈΡ… капілярів, Π° Ρ‚Π°ΠΊΠΎΠΆ судин Π΄Π΅Ρ†ΠΈΠ΄ΡƒΠ°Π»ΡŒΠ½ΠΎΡ— ΠΎΠ±ΠΎΠ»ΠΎΠ½ΠΊΠΈ Π·ΠΌΠ΅Π½ΡˆΡƒΡ”Ρ‚ΡŒΡΡ. ΠΠ°ΠΉΠ±Ρ–Π»ΡŒΡˆ Π²ΠΈΡ€Π°ΠΆΠ΅Π½Ρ– Π·ΠΌΡ–Π½ΠΈ СкспрСсії Π΅NOS спостСрігали ΠΏΡ€ΠΈ ΠΏΠΎΡ”Π΄Π½Π°Π½Π½Ρ– дисфункції ΠΏΠ»Π°Ρ†Π΅Π½Ρ‚ΠΈ Ρ‚Π° Π·Π°Π»Ρ–Π·ΠΎΠ΄Π΅Ρ„Ρ–Ρ†ΠΈΡ‚Π½ΠΎΡ— Π°Π½Π΅ΠΌΡ–Ρ— Ρƒ вигляді ΠΏΠ°Ρ€Π°Π΄ΠΎΠΊΡΠ°Π»ΡŒΠ½ΠΎΠ³ΠΎ зростання СкспрСсії. Π¦Π΅ ΡΠ²Ρ–Π΄Ρ‡ΠΈΡ‚ΡŒ ΠΏΡ€ΠΎ Π½Π΅ΠΎΠ±Ρ…Ρ–Π΄Π½Ρ–ΡΡ‚ΡŒ ΠΊΠΎΡ€Π΅ΠΊΡ†Ρ–Ρ— Π΅Π½Π΄ΠΎΡ‚Π΅Π»Ρ–Π°Π»ΡŒΠ½ΠΎΡ— Ρ„ΡƒΠ½ΠΊΡ†Ρ–Ρ— Ρƒ ΠΆΡ–Π½ΠΎΠΊ Π· Π°Π½Π΅ΠΌΡ–Ρ”ΡŽ Π²Π°Π³Ρ–Ρ‚Π½ΠΈΡ….The pertinence of the study is related to a large prevalence of dysfunction of the placenta in pregnant women suffering from anemia. To evaluate the immunohistochemical expression characteristics of endothelial NO-synthase (eNOS) in the placenta during its dysfunction in women against the background of anemia 30 samples of placental tissue were studied with the use of immunohistochemical and micrometer methods. Materials and results. It was found that the expression of eNOS in patients with iron defi ciency anemia in the cytoplasm of syncytium of villi and fetal capillary endothelium as well as decidual vessels decreases, with the most pronounced changes in the expression of eNOS observed in the presence of the combination of placental dysfunction and iron defi ciency anemia in the form of paradoxical increase in expression. Conclusion. This indicates the necessity for correction of endothelial function in women with anemia during pregnancy.ΠΠΊΡ‚ΡƒΠ°Π»ΡŒΠ½ΠΎΡΡ‚ΡŒ исслСдования обусловлСна Π·Π½Π°Ρ‡ΠΈΡ‚Π΅Π»ΡŒΠ½ΠΎΠΉ Ρ€Π°ΡΠΏΡ€ΠΎΡΡ‚Ρ€Π°Π½Π΅Π½Π½ΠΎΡΡ‚ΡŒΡŽ дисфункции ΠΏΠ»Π°Ρ†Π΅Π½Ρ‚Ρ‹ Ρƒ Π±Π΅Ρ€Π΅ΠΌΠ΅Π½Π½Ρ‹Ρ…, ΡΡ‚Ρ€Π°Π΄Π°ΡŽΡ‰ΠΈΡ… Π°Π½Π΅ΠΌΠΈΠ΅ΠΉ. Π‘ Ρ†Π΅Π»ΡŒΡŽ ΠΎΡ†Π΅Π½ΠΊΠΈ иммуногистохимичСских особСнностСй экспрСссии ΡΠ½Π΄ΠΎΡ‚Π΅Π»ΠΈΠ°Π»ΡŒΠ½ΠΎΠΉ NO-синтазы (eNOS) Π² ΠΏΠ»Π°Ρ†Π΅Π½Ρ‚Π΅ ΠΏΡ€ΠΈ Π΅Π΅ дисфункции Ρƒ ΠΆΠ΅Π½Ρ‰ΠΈΠ½ Π½Π° Ρ„ΠΎΠ½Π΅ Π°Π½Π΅ΠΌΠΈΠΈ ΠΏΡ€ΠΎΠ²Π΅Π΄Π΅Π½ΠΎ исслСдованиС 30 ΠΎΠ±Ρ€Π°Π·Ρ†ΠΎΠ² ΠΏΠ»Π°Ρ†Π΅Π½Ρ‚Π°Ρ€Π½ΠΎΠΉ Ρ‚ΠΊΠ°Π½ΠΈ с ΠΏΡ€ΠΈΠΌΠ΅Π½Π΅Π½ΠΈΠ΅ΠΌ иммуногистохимичСского ΠΈ микромСтричСского ΠΌΠ΅Ρ‚ΠΎΠ΄ΠΎΠ². УстановлСно, Ρ‡Ρ‚ΠΎ экспрСссия Π΅NOS Ρƒ ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΎΠΊ с ΠΆΠ΅Π»Π΅Π·ΠΎΠ΄Π΅Ρ„ΠΈΡ†ΠΈΡ‚Π½ΠΎΠΉ Π°Π½Π΅ΠΌΠΈΠ΅ΠΉ Π² Ρ†ΠΈΡ‚ΠΎΠΏΠ»Π°Π·ΠΌΠ΅ синцития ворсинок ΠΈ эндотСлия Ρ„Π΅Ρ‚Π°Π»ΡŒΠ½Ρ‹Ρ… капилляров, Π° Ρ‚Π°ΠΊΠΆΠ΅ сосудов Π΄Π΅Ρ†ΠΈΠ΄ΡƒΠ°Π»ΡŒΠ½ΠΎΠΉ ΠΎΠ±ΠΎΠ»ΠΎΡ‡ΠΊΠΈ ΡƒΠΌΠ΅Π½ΡŒΡˆΠ°Π΅Ρ‚ΡΡ. НаиболСС Π²Ρ‹Ρ€Π°ΠΆΠ΅Π½Π½Ρ‹Π΅ измСнСния экспрСссии Π΅NOS Π½Π°Π±Π»ΡŽΠ΄Π°ΡŽΡ‚ ΠΏΡ€ΠΈ сочСтании дисфункции ΠΏΠ»Π°Ρ†Π΅Π½Ρ‚Ρ‹ ΠΈ ΠΆΠ΅Π»Π΅Π·ΠΎΠ΄Π΅Ρ„ΠΈΡ†ΠΈΡ‚Π½ΠΎΠΉ Π°Π½Π΅ΠΌΠΈΠΈ Π² Π²ΠΈΠ΄Π΅ ΠΏΠ°Ρ€Π°Π΄ΠΎΠΊΡΠ°Π»ΡŒΠ½ΠΎΠ³ΠΎ роста экспрСссии. Π­Ρ‚ΠΎ ΡΠ²ΠΈΠ΄Π΅Ρ‚Π΅Π»ΡŒΡΡ‚Π²ΡƒΠ΅Ρ‚ ΠΎ нСобходимости ΠΊΠΎΡ€Ρ€Π΅ΠΊΡ†ΠΈΠΈ ΡΠ½Π΄ΠΎΡ‚Π΅Π»ΠΈΠ°Π»ΡŒΠ½ΠΎΠΉ Ρ„ΡƒΠ½ΠΊΡ†ΠΈΠΈ Ρƒ ΠΆΠ΅Π½Ρ‰ΠΈΠ½ с Π°Π½Π΅ΠΌΠΈΠ΅ΠΉ Π±Π΅Ρ€Π΅ΠΌΠ΅Π½Π½Ρ‹Ρ…

    Morphologic and Immune-histochemic Peculiarities of Placenta in Its Dysfunction in Anemia of Pregnancy.

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    Placental dysfunction occurs in 17-35% of pregnant women. Iron deficiency anemia complicating pregnancy and childbirth affects fetal development. In its turn, pregnancy contributes to the rapid progress of iron deficiency anemia. The aim of the study was to evaluate the morphological and immunohistochemical features of the placenta in its dysfunction in women with anemia during pregnancy. The study was performed on clinical bases of the Department of Obstetrics and Gynecology β„–1 of ONMedU (Odessa) and pathologic department of SI " IPOG NAMSU" (Kiev). The complex dynamic examination of pregnant women with subsequent examination of the placenta was performed. Patients were divided into 3 groups. 1st group consisted of pregnant women with physiological pregnancy and childbirth (n=10), 2nd group included women suffering from anemia during pregnancy (n=10); 3rd group consisted of women with pregnancy accompanied with placental dysfunction and anemia (n=10). Organometric, macroscopic, general histological, micrometer, histochemical and immunohistochemical methods were used. It is shown that reduction of incidence of regeneration - proliferative marker Ki -67 in the nuclei of villous syncytial structure is more pronounced in the development of placental dysfunction against a background of anemia during pregnancy

    Nitric Oxide Synthase Expression in Placental Tissue in Iron Deficiency Anemia

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    One of the most important pathogenetic mechanisms of pregnancy complications are disregulation changes caused by the functioning disturbance of the nitric oxide depending (nitrergic) systems. Hypoxia occuring in iron deficiency anemia affects the activity of guanylate cyclase, which is an oxygen acceptor and intimately depends on the nitric oxide production. Thus, iron deficiency acts as a trigger for mediation violation of nitrergic system.The objective of the study was to evaluate the expression of endothelial nitric oxide synthase (eNOS) in placental tissue of the patients with iron deficiency anemia.The research was conducted at the maternity home β„– 2 (Odessa) and pathomorphology department of SI "IPAG NAMSU", Kyiv). 20 pregnant women were examined. They were divided into two groups: I (control group) included10 women with physiological pregnancy and childbirth and II (experimental group) included 10 women suffering from iron deficiency anemia during pregnancy. The level of eNOS expression was assessed with the use of immunohistochemical method.The expression of eNOS in placental tissue of women giving birth who had signs of iron deficiency anemia during the whole period of gestation, decreases in both the cytoplasm of syncytium villi and endothelium of fetal capillaries, and cytoplasm of vascular endothelial decidua. The described changes in the expression of eNOS may act as prerequisites for the development of endothelial dysfunction and associated pathological conditions during pregnancy
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