Developing start-ups with academic support in Romania

[EN] The objective of the paper is to present how experts from Spiru Haret University have been involved in the development and implementation of a project aimed at the start-up development in the Central region of Romania, This project runs within one of the first European funded programs where universities are eligible. The project ran through the first stage of entrepreneurship training by September 2018, where 371 members of the target group (of the 403 selected) completed an entrepreneurial training course, supported by academic staff. Subsequently, a business plan competition was organized in two sessions (in November and December 2018), following which 38 business plans were selected, the ones selected attended training in the same industry they intend to develop their business. By July 2020, the 38 selected entrepreneurs will benefit from counseling and mentoring services, along with the monitoring of the business plan.Andronic, A.; Andronic, R.; Cruceru, G. (2019). Developing start-ups with academic support in Romania. En HEAD'19. 5th International Conference on Higher Education Advances. Editorial Universitat Politècnica de València. 1187-1195. https://doi.org/10.4995/HEAD19.2019.9253OCS1187119

Ecotourism - the Main Form of Tourism Exploitation of Protected Natural Areas

The ecotourism has a significant role in the economic development of this zones or regionsas tourist attractions. The most important positive contributions refers to the state revenue generatedby tourist spending and export / import of goods complementary for receiving countries, and the boostof investment in various sectors, so the multiplier effect of tourism by contributing to the economicprosperity of the country. Tourist activities carried out under the banner of ecotourism offeropportunities specific to the local population and tourist industry is forced to use natural resources ina sustainable manner and to assess the valuable natural and cultural objectives. As reflected in thevarious views reflected in literature, ecotourism is also an industry in the tourist market, designed tomeet the special travel needs. Because these approaches can be considered ecotourism and tourismmarket segment, having a common language with cultural and rural tourism, as demonstratedpreviously. Originally designed as an alternative to mass tourism, ecotourism is materialized as asolution to combat negative effects and minimize impacts on natural ecosystems

Multidrug resistance in Helicobacter pylori infection

Helicobacter pylori (Hp), a well-known human pathogen, causes one of the most common chronic bacterial infections and plays an important role in the emergence of chronic progressive gastric inflammation and a variety of gastrointestinal diseases. The prevalence of Hp infection varies worldwide and is indirectly proportional to socio-economic status, especially during childhood. The response to the eradication therapy significantly depends on the antibiotic resistance specific to each geographical region; thus, currently, given the increasing prevalence of antimicrobial resistance (especially to clarithromycin, metronidazole, and levofloxacin), successful treatment for Hp eradication has become a real challenge and a critical issue. The most incriminated factors associated with multidrug resistance (MDR) in Hp proved to be the overuse or the improper use of antibiotics, poor medication adherence, and bacterial-related factors including efflux pumps, mutations, and biofilms. Up to 30% of first-line therapy fails due to poor patient compliance, high gastric acidity, or high bacteremia levels. Hence, it is of great importance to consider new eradication regimens such as vonoprazan-containing triple therapies, quintuple therapies, high-dose dual therapies, and standard triple therapies with probiotics, requiring further studies and thorough assessment. Strain susceptibility testing is also necessary for an optimal approach

3-D Echocardiography Is Feasible and More Reproducible than 2-D Echocardiography for In-Training Echocardiographers in Follow-up of Patients with Heart Failure with Reduced Ejection Fraction

Left ventricular volumes (LVVs) and ejection fraction (LVEF) are key elements in the evaluation and follow-up of patients with heart failure with reduced ejection fraction (HFrEF). Therefore, a feasible and reproducible imaging method to be used by both experienced and in-training echocardiographers is mandatory. Our aim was to establish if, in a large echo lab, echocardiographers in-training provide feasible and more reproducible results for the evaluation of patients with HFrEF when using 3-dimensional echocardiography (3-DE) versus 2-dimensional echocardiography (2-DE). Sixty patients with HFrEF (46 males, age: 58 ± 17 y) underwent standard transthoracic 2-D acquisitions and 3-D multibeat full volumes of the left ventricle. One expert user in echocardiography (expert) and three echocardiographers with different levels of training in 2-DE (beginner, medium and advanced) measured the 2-D LVVs and LVEFs on the same consecutive images of patients with HFrEF. Afterward, the expert performed a 1-mo training in 3-DE analysis of the users, and both the expert and trainees measured the 3-D LVVs and LVEF of the same patients. Measurements provided by the expert and all trainees in echo were compared. Six patients were excluded from the study because of poor image quality. The mean end-diastolic LVV of the remaining 54 patients was 214 ± 75 mL with 2-DE and 233 ± 77 mL with 3-DE. Mean LVEF was 35 ± 10% with 2-DE and 33 ± 10% with 3-DE. Our analysis revealed that, compared with the expert user, the trainees had acceptable reproducibility for the 2-DE measurements, according to their level of expertise in 2-DE (intra-class coefficients [ICCs] ranging from 0.75 to 0.94). However, after the short training in 3-DE, they provided feasible and more reproducible measurements of the 3-D LVVs and LVEF (ICCs ranging from 0.89-0.97) than they had with 2-DE. 3-DE is a feasible, rapidly learned and more reproducible method for the assessment of LVVs and LVEF than 2-DE, regardless of the basic level of expertise in 2-DE of the trainees in echocardiography. In echo labs with a wide range of staff experience, 3-DE might be a more accurate method for the follow-up of patients with HFrEF

Comparative Analysis of the Evolution of Business Travel Romania – Bulgaria

The authors aim to analyze the evolution of the main tourism indicators in the two neighboringcountries Romania and Bulgaria. Current development of tourism is characterized by a profound renewal ofthe world tourism offer, in particular by developing a range of new tourism products, superior bothqualitatively and quantitatively. Romanian tourism revival will involve reshaping the development of tourismproducts based incentives at national and international tourism. Currently, the Romanian tourism, asotherwise the world is characterized by fierce competition between destinations. Tourist destinations, be theystate or country itself, are becoming increasingly need a new model of tourism policy which influence theircompetitive position in the current competition. A special role in perception destination in the competition ofsimilar offers in the country is playing tourist brand or regional. Tourists and demanding consumers are animportant factor for competitive advantage of a destination. Adapt to offer the consumer needs to be spottednew trends and new opportunities to the tourism product. In the spatial extent of tourism development policy,most have a national or regional scope (in that country). Outside Europe, where international cooperation intourism development is emphasized through the integration of countries within the EU, internationalcooperation is early, sometimes reduced to statements of intent. The competitive position of a destinationdepends on the type thereof, namely the socio-economic development, landscape features, climate, culture,political factors etc. The success of tourist destinations is determined by how it manages to ensure at the sametime to ensure visitors throughout its entire offer experience to match or exceed many alternative destinations

69 Ecotourism - the Main Form of Tourism Exploitation of Protected Natural Areas

The ecotourism has a significant role in the economic development of this zones or regionsas tourist attractions. The most important positive contributions refers to the state revenue generatedby tourist spending and export / import of goods complementary for receiving countries, and the boostof investment in various sectors, so the multiplier effect of tourism by contributing to the economicprosperity of the country. Tourist activities carried out under the banner of ecotourism offeropportunities specific to the local population and tourist industry is forced to use natural resources ina sustainable manner and to assess the valuable natural and cultural objectives. As reflected in thevarious views reflected in literature, ecotourism is also an industry in the tourist market, designed tomeet the special travel needs. Because these approaches can be considered ecotourism and tourismmarket segment, having a common language with cultural and rural tourism, as demonstratedpreviously. Originally designed as an alternative to mass tourism, ecotourism is materialized as asolution to combat negative effects and minimize impacts on natural ecosystems