Validation of the Simple Activity Measurement Instrument (SAM) Using Heart Rate and Pedometry; Simple Activity Measurement Instrument (SAM) for Measuring MVPA in Physical Education

In order to battle obesity in our schools, Physical Education standards are working to become more and more in accordance with the Physical Activity Guidelines set by the U.S. Department of Health and Human Services, and the American College of Sports Medicine. Physical Education teachers would benefit from a tool that measures the amount and type of activity that students are involved in while they are in Physical Education. Many of the instruments that teachers use to assess students’ physical activity are too expensive, too difficult and can be time consuming. The purpose of the current study was to test the reliability of a tool developed by Surapiboonchai, Fumey, Reardon, Eldridge and Murray known as the Simple Activity Measurement (SAM) instrument. The instrument was used to assess MVPA during Physical Education classes. 40 students, both male and female, were randomly selected to represent the population (grades 9-12) at Moriarty High School. The students that were observed for MPVA wore a Pyle PHRM34 Heart Rate Monitor along with an Omron HJ-112 Premium Pedometer. The intensity of their activity was recorded on scale from 0-10. The SAM instrument was proven to be valid measurement of physical activity and a high predictor of Heart Rate (r = 0.838, ^ = 0.702, p \u3c 0.05) as well as a valid predictor of accelerator use (r = 0.591, r^ = 0.349). The results of the study show that SAM is an economical and easy instrument to use to assess MVPA in Physical Education classes in grades 9-1

Management of pregnancy in patients with exstrophy-epispadias sequence: a case series and literature review

Exstrophy-epispadias sequence is an uncommon diagnosis in which surgical reconstruction has increased quality of life for these patients. As they are entering the reproductive phase of their life, consideration must be made for management of their pregnancies in the context of their genitourinary reconstruction. There have been few case reports of patients with cloacal exstrophy conceiving; therefore, information to guide management of their pregnancies is limited. Here we describe a patient with Omphalocele-Exstrophy-Imperforate Anus-Spinal defects (OEIS) and a patient with a history of bladder exstrophy both with spontaneous pregnancy managed by a multidisciplinary approach and primary cesarean delivery

App móvil basado en servicios para la gestión de repartos en la empresa Roal Servicios y Distribución S.A.C

La presente investigación se realizó la búsqueda de información por conceptos clave en bibliotecas indexadas y repositorios de universidades enfocado al filtrado de las referencias bibliográficas para trabajo previo, antecedentes y marco teórico, basado en la revisión de la metodología científica empleada en los estudios realizados anteriormente, la propuesta conceptual y de indicadores para el objeto de estudio. La investigación tuvo un estudio de tipo Aplicada, con diseño preexperimental y un enfoque de investigación cuantitativo. Para la población para la investigación se usará cantidad de Pedidos de ventas por el periodo de un mes y la muestra es de 384 pedidos de ventas. Dentro de la empresa ROAL Servicios y Distribución S.A.C. se viene realizando los pedidos vía telefónica y sin ningún tipo de seguimiento en tiempo real generando deficiencias, así teniendo quejas de un 60% de los clientes que se encuentran insatisfechos con sus pedidos y la impuntualidad de la entrega, ya que se encuentra sin una aplicación Móvil que permita realizar la gestión des repartos de forma eficiente y la ubicación a tiempo real del repartidor, Lo que se pretende la investigación es cubrir la necesidad de determinar la influencia App móvil basado en servicios para la gestión de repartos en la empresa ROAL Servicios y Distribución S.A.C

App Móvil con Geolocalización basado en la metodología SCRUM para la Gestión de Repartos en la empresa ROAL Servicios y Distribución S.A.C.

En la actualidad, se están produciendo cambios en el ámbito digital que están teniendo un impacto en los procesos de entrega de productos y distribución de servicios a diferentes niveles. Estos cambios están relacionados con la realización de pedidos y entregas a través de teléfono sin un seguimiento en tiempo real, lo cual genera deficiencias en el sistema. El objetivo de este proyecto es implementar un sistema de gestión de reparaciones en la empresa ROAL Servicios y Distribución S.A.C. mediante una aplicación móvil que utiliza la metodología ágil SCRUM. Para llevar a cabo la investigación, se utilizó un enfoque cuantitativo de tipo aplicado, y se empleó un diseño experimental puro. Se recolectaron datos utilizando análisis documental y fichas de observación, con una muestra de 30 clientes de la población objetivo. En cuanto al hardware, se utilizó una computadora, teléfono, USB, libreta de apuntes y disco duro, mientras que el software utilizado incluye Android Studio, Java y Firebase. Los resultados obtenidos para cada uno de los indicadores han mostrado mejoras en el grupo experimental en comparación con el grupo de control. Como conclusión, se determinó que la implementación de la aplicación móvil basada en la metodología ágil SCRUM reduce el tiempo necesario para registrar los pedidos de los clientes en ROAL Servicios y Distribución S.A.C. Se recomienda mejorar los diseños de las interfaces de usuario para que sean más intuitivas y fáciles de usar, sin alterar significativamente el flujo principal del sistema

Impact of metabolic syndrome on the outcomes of superficial femoral artery interventions

BackgroundMetabolic syndrome (MetSyn) is an epidemic in the United States and is associated with early onset of atherosclerosis, increased thrombotic events, and increased complications after cardiovascular intervention. MetSyn is found in ∼50% of patients with peripheral vascular disease. However, its impact on peripheral interventions is unknown. The aim of this study is to determine the outcomes of superficial femoral artery (SFA) interventions in patients with and without MetSyn.MethodsA database of patients undergoing endovascular treatment of SFA disease between 1999 and 2009 was retrospectively queried. MetSyn was defined as the presence of ≥3 of the following criteria: blood pressure ≥130 mm Hg/≥85 mm Hg; triglycerides ≥150 mg/dL; high-density lipoprotein ≤50 mg/dL for women and ≤40 mg/dL for men; fasting blood glucose ≥110 mg/dL; or body mass index ≥30 kg/m2. Kaplan-Meier survival analyses were performed to assess time-dependent outcomes. Factor analyses were performed using a Cox proportional hazard model for time-dependent variables.ResultsA total of 1018 limbs in 738 patients (64% male, average age 67 years) underwent endovascular treatment for symptomatic SFA disease with 45% of patients meeting the criteria for MetSyn. MetSyn patients were more likely to be female (P = .001), to present with critical ischemia (rest pain/tissue loss: 55% MetSyn vs 45% non-MetSyn; P = .001), have poorer ambulatory status (P = .001), and have more advanced SFA lesions (TransAtlantic Inter-Society Consensus II C/D: 51% vs 11%; P = .001) and worse tibial runoff (P = .001). MetSyn patients required more complex interventions (P = .0001). There was no difference in mortality and major adverse cardiac events, but systemic complications (4% vs 1%; P = .001) and major adverse limb events (12% vs 7%; P = .0009) were significantly higher in the MetSyn group. Immediate postprocedural hemodynamic improvement, resolved or improved symptoms, and restoration of impaired ambulation were equivalent in both groups. Early failure (<6 months) was more common in those with MetSyn. At 5 years, primary, assisted primary, and secondary patencies were not affected by the presence of MetSyn. The presence of MetSyn was associated with a decrease in clinical efficacy, decreased freedom from recurrent symptoms, and decreased freedom from major amputation at 5 years.ConclusionsMetSyn is present in nearly half of the patients presenting with SFA disease. These patients present with more advanced disease and have poorer symptomatic and functional outcomes compared with those patients without MetSyn

Characterization of S3Pvac Anti-Cysticercosis Vaccine Components: Implications for the Development of an Anti-Cestodiasis Vaccine

Background: Cysticercosis and hydatidosis seriously affect human health and are responsible for considerable economic loss in animal husbandry in non-developed and developed countries. S3Pvac and EG95 are the only field trial-tested vaccine candidates against cysticercosis and hydatidosis, respectively. S3Pvac is composed of three peptides (KETc1, GK1 and KETc12), originally identified in a Taenia crassiceps cDNA library. S3Pvac synthetically and recombinantly expressed is effective against experimentally and naturally acquired cysticercosis.Methodology/ Principal Findings: In this study, the homologous sequences of two of the S3Pvac peptides, GK1 and KETc1, were identified and further characterized in Taenia crassiceps WFU, Taenia solium, Taenia saginata, Echinococcus granulosus and Echinococcus multilocularis. Comparisons of the nucleotide and amino acid sequences coding for KETc1 and GK1 revealed significant homologies in these species. The predicted secondary structure of GK1 is almost identical between the species, while some differences were observed in the C terminal region of KETc1 according to 3D modeling. A KETc1 variant with a deletion of three C-terminal amino acids protected to the same extent against experimental murine cysticercosis as the entire peptide. on the contrary, immunization with the truncated GK1 failed to induce protection. Immunolocalization studies revealed the non stage-specificity of the two S3Pvac epitopes and their persistence in the larval tegument of all species and in Taenia adult tapeworms.Conclusions/ Significance: These results indicate that GK1 and KETc1 may be considered candidates to be included in the formulation of a multivalent and multistage vaccine against these cestodiases because of their enhancing effects on other available vaccine candidates

Impact of COVID-19 on cardiovascular testing in the United States versus the rest of the world

Objectives: This study sought to quantify and compare the decline in volumes of cardiovascular procedures between the United States and non-US institutions during the early phase of the coronavirus disease-2019 (COVID-19) pandemic. Background: The COVID-19 pandemic has disrupted the care of many non-COVID-19 illnesses. Reductions in diagnostic cardiovascular testing around the world have led to concerns over the implications of reduced testing for cardiovascular disease (CVD) morbidity and mortality. Methods: Data were submitted to the INCAPS-COVID (International Atomic Energy Agency Non-Invasive Cardiology Protocols Study of COVID-19), a multinational registry comprising 909 institutions in 108 countries (including 155 facilities in 40 U.S. states), assessing the impact of the COVID-19 pandemic on volumes of diagnostic cardiovascular procedures. Data were obtained for April 2020 and compared with volumes of baseline procedures from March 2019. We compared laboratory characteristics, practices, and procedure volumes between U.S. and non-U.S. facilities and between U.S. geographic regions and identified factors associated with volume reduction in the United States. Results: Reductions in the volumes of procedures in the United States were similar to those in non-U.S. facilities (68% vs. 63%, respectively; p = 0.237), although U.S. facilities reported greater reductions in invasive coronary angiography (69% vs. 53%, respectively; p < 0.001). Significantly more U.S. facilities reported increased use of telehealth and patient screening measures than non-U.S. facilities, such as temperature checks, symptom screenings, and COVID-19 testing. Reductions in volumes of procedures differed between U.S. regions, with larger declines observed in the Northeast (76%) and Midwest (74%) than in the South (62%) and West (44%). Prevalence of COVID-19, staff redeployments, outpatient centers, and urban centers were associated with greater reductions in volume in U.S. facilities in a multivariable analysis. Conclusions: We observed marked reductions in U.S. cardiovascular testing in the early phase of the pandemic and significant variability between U.S. regions. The association between reductions of volumes and COVID-19 prevalence in the United States highlighted the need for proactive efforts to maintain access to cardiovascular testing in areas most affected by outbreaks of COVID-19 infection