EFEITO AGUDO DA CORRIDA COM OS PÉS DESCALÇO SOBRE AS COMPONENTES ANTEROPOSTERIOR E MEDIOLATERAL DA FORÇA DE REAÇÃO DO SOLO

This study investigated the short-term effects of barefoot running on selected parameters of the anteroposterior and mediolateral components of the Ground Reaction Force (GRF) in runners used to wearing athletic shoes. Seventy-one recreational runners, inexperienced in barefoot running, ran at a self-selected speed for a distance of 9 meters on a fixed floor equipped with force platforms, under two conditions: shod and barefoot. The braking and acceleration peaks of the anteroposterior component, as well as the minimum and maximum peaks of the mediolateral component were obtained. The braking peak was lower, while the acceleration peak was higher in barefoot running. In contrast, the magnitude of both the minimum and maximum peaks were greater in the barefoot condition. In summary, barefoot running acutely alters selected parameters of the anteroposterior and mediolateral components of the FRS related to the overload and performance of runners used to wearing sports shoes.Este estudio investigó el efecto agudo de correr descalzo en parámetros seleccionados de los componentes anteroposterior y mediolateral de la fuerza de reacción del suelo (FRS) en corredores acostumbrados a usar calzado deportivo. Setenta y un corredores recreativos, sin experiencia en correr descalzo, corrieron a una velocidad autoseleccionada por una distancia de 30 pies en un piso fijo equipado con plataformas de fuerza, bajo dos condiciones: zapatos y descalzo. Se obtuvieron los picos de frenado y aceleración de la componente anteroposterior, así como los picos mínimos y máximos de la componente mediolateral. El pico de frenado fue menor, mientras que el pico de aceleración fue mayor al correr descalzo. Por el contrario, la magnitud de los picos tanto mínimo como máximo fue mayor en la condición de descalzo. En resumen, correr descalzo altera de forma aguda parámetros seleccionados de los componentes anteroposterior y mediolateral del FRS relacionados con la sobrecarga y el rendimiento de los corredores acostumbrados a llevar calzado deportivo.Este estudo investigou o efeito agudo da corrida descalço sobre parâmetros selecionados das componentes anteroposterior e mediolateral da Força de Reação do Solo (FRS) em corredores habituados ao uso do calçado esportivo. Setenta e um corredores recreacionais, inexperientes em corrida descalço, correram em velocidade auto-selecionada por uma distância de 9 metros em piso fixo equipado com plataformas de força, sob duas condições: calçados e descalços. Os picos de frenagem e aceleração da componente anteroposterior, bem como os picos mínimo e máximo da componente mediolateral foram obtidos. O pico de frenagem foi menor, enquanto o pico de aceleração foi maior na corrida descalço. Em contrapartida, a magnitude de ambos os picos mínimo e máximo foram maiores na condição descalço. Em síntese, a corrida descalço altera agudamente parâmetros selecionados das componentes anteroposterior e mediolateral da FRS relacionados à sobrecarga e ao desempenho de corredores habituados ao uso do calçado esportivo

Biomass and leaf acclimations to ultraviolet solar radiation in juvenile plants of Coffea arabica and C. Canephora

E-26/202.323/2017 E-26/202.759/2018 E-26/210.309/2018 E-26/210.037/2020 PV 312959/2019-2 PQ 300996/2016 PVS 00583/20 UID/04129/2020 Funding Information: The authors acknowledge Funda??o Carlos Chagas de Apoio ? Pesquisa do Estado do Rio de Janeiro (FAPERJ) (Grants E-26/202.323/2017, WPR; E-26/202.759/2018, E-26/210.309/2018 and E-26/210.037/2020, EC), CNPq (awarded the fellowships: PV 312959/2019-2, MR; PQ 300996/2016, EC), and PVS 00583/20, EC FAPEMA (Funda??o de Amparo ? Pesquisa e ao Desenvolvimento Cient?fico e Tecnol?gico do Maranh?o), all from Brazil. Support from Funda??o para a Ci?ncia e a Tecnologia I.P., Portugal, to J.C.R. through the units UID/04129/2020 (CEF) and UIDP/04035/2020 (GeoBioTec) is also greatly acknowledged. Publisher Copyright: © 2021 by the authors. Licensee MDPI, Basel, Switzerland.Despite the negative impacts of increased ultraviolet radiation intensity on plants, these organisms continue to grow and produce under the increased environmental UV levels. We hypothe-sized that ambient UV intensity can generate acclimations in plant growth, leaf morphology, and photochemical functioning in modern genotypes of Coffea arabica and C. canephora. Coffee plants were cultivated for ca. six months in a mini greenhouse under either near ambient (UVam) or reduced (UVre) ultraviolet regimes. At the plant scale, C. canephora was substantially more impacted by UVam when compared to C. arabica, investing more carbon in all juvenile plant components than under UVre. When subjected to UVam, both species showed anatomic adjustments at the leaf scale, such as increases in stomatal density in C. canephora, at the abaxial and adaxial cuticles in both species, and abaxial epidermal thickening in C. arabica, although without apparent impact on the thickness of palisade and spongy parenchyma. Surprisingly, C. arabica showed more efficient energy dissipation mechanism under UVam than C. canephora. UVam promoted elevated protective carotenoid content and a greater use of energy through photochemistry in both species, as reflected in the photochemical quenching increases. This was associated with an altered chlorophyll a/b ratio (significantly only in C. arabica) that likely promoted a greater capability to light energy capture. Therefore, UV levels promoted different modifications between the two Coffea sp. regarding plant biomass production and leaf morphology, including a few photochemical differences between species, suggesting that modifications at plant and leaf scale acted as an acclimation response to actual UV intensity.publishersversionpublishe

Frequency and functional activity of Th17, Tc17 and other T-cell subsets in Systemic Lupus Erythematosus

To compare frequency and functional activity of peripheral blood (PB) Th(c)17, Th(c)1 and Treg cells and the amount of type 2 cytokines mRNA we recruited SLE patients in active (n = 15) and inactive disease (n = 19) and healthy age- and gender-matched controls (n = 15). The study of Th(c)17, Th(c)1 and Treg cells was done by flow cytometry and cytokine mRNA by real-time PCR. Compared to NC, SLE patients present an increased proportion of Th(c)17 cells, but with lower amounts of IL-17 per cell and also a decreased frequency of Treg, but with increased production of TGF-b and FoxP3 mRNA. In active compared to inactive SLE, there is a marked decreased in frequency of Th(c)1 cells, an increased production of type 2 cytokines mRNA and a distinct functional profile of Th(c)17 cells. Our findings suggest a functional disequilibrium of T-cell subsets in SLE which may contribute to the inflammatory process and disease pathogenesis

COMPARAÇÃO BIOMECÂNICA DA CORRIDA ENTRE INDIVÍDUOS COM DIFERENTES NÍVEIS DE FORÇA DE MEMBROS INFERIORES

Running is a practice widely used by those who aim to maintain or improve their physical fitness. Strength training has been recommended to increase performance and reduce injury risk in runners, however, the relationship between muscle strength and running mechanics still requires a better understanding. The aim of the present study was to compare the running biomechanics among bodybuilders, with different levels of absolute strength in the back squat. Initially, 24 volunteers participated in the study. Based on the 10RM absolute strength in the back squat, the volunteers were divided into tertiles: upper strength group (GFS), lower strength group (GFI) and medium strength group. For comparison of running mechanics, GFS and GFI were gained. Dynamic and kinematic parameters were collected during treadmill running. There were no differences between groups for any of the investigated variables. Keywords: Running mechanics; Muscle strength; Locomotion.Correr es una práctica muy utilizada por quienes tienen como objetivo mantener o mejorar su forma física. El entrenamiento de fuerza se ha recomendado como una forma de aumentar el rendimiento y reducir el riesgo de lesiones en los corredores, sin embargo, la relación entre la fuerza muscular y la mecánica de carrera aún requiere una mejor comprensión. El objetivo del presente estudio fue comparar la biomecánica de la carrera entre culturistas, con diferentes niveles de fuerza absoluta en la sentadilla. Inicialmente, participaron en el estudio 24 voluntarios. Con base en la fuerza absoluta de 10RM en la sentadilla, los voluntarios se dividieron en terciles: grupo de fuerza superior (GFS), grupo de fuerza inferior (GFI) y grupo de fuerza media. Para comparar la mecánica de la carrera, se obtuvieron GFS y GFI. Los parámetros dinámicos y cinemáticos se recopilaron durante la carrera en cinta. No hubo diferencias entre los grupos para ninguna de las variables investigadas. Palabras clave: mecánica de carrera; Fuerza muscular; Locomoción.A corrida é uma prática largamente utilizada por aqueles que almejam manter ou aprimorar a aptidão física. O treinamento de força tem sido recomendado como forma de aumentar o desempenho e reduzir o risco de lesão em praticantes de corrida, no entanto, a relação entre força muscular e mecânica da corrida ainda necessita de melhor compreensão. O objetivo do presente estudo foi comparar a biomecânica da corrida entre indivíduos praticantes de musculação, com diferentes níveis de força absoluta no agachamento. Inicialmente participaram do estudo 24 voluntários. Baseado na força absoluta em 10RM no agachamento, os voluntários foram divididos em tercis: grupo de força superior (GFS), grupo de força inferior (GFI) e grupo de força mediana. Para comparação da mecânica da corrida foram analisados o GFS e GFI. Foram coletados parâmetros dinâmicos e cinemáticos durante corrida em esteira. Não se observou diferenças entre os grupos para nenhuma das variáveis investigadas. Palavras-chave: Mecânica da corrida; Força muscular; Locomoção

Racial differences in systemic sclerosis disease presentation: a European Scleroderma Trials and Research group study

Objectives. Racial factors play a significant role in SSc. We evaluated differences in SSc presentations between white patients (WP), Asian patients (AP) and black patients (BP) and analysed the effects of geographical locations.Methods. SSc characteristics of patients from the EUSTAR cohort were cross-sectionally compared across racial groups using survival and multiple logistic regression analyses.Results. The study included 9162 WP, 341 AP and 181 BP. AP developed the first non-RP feature faster than WP but slower than BP. AP were less frequently anti-centromere (ACA; odds ratio (OR) = 0.4, P < 0.001) and more frequently anti-topoisomerase-I autoantibodies (ATA) positive (OR = 1.2, P = 0.068), while BP were less likely to be ACA and ATA positive than were WP [OR(ACA) = 0.3, P < 0.001; OR(ATA) = 0.5, P = 0.020]. AP had less often (OR = 0.7, P = 0.06) and BP more often (OR = 2.7, P < 0.001) diffuse skin involvement than had WP.AP and BP were more likely to have pulmonary hypertension [OR(AP) = 2.6, P < 0.001; OR(BP) = 2.7, P = 0.03 vs WP] and a reduced forced vital capacity [OR(AP) = 2.5, P < 0.001; OR(BP) = 2.4, P < 0.004] than were WP. AP more often had an impaired diffusing capacity of the lung than had BP and WP [OR(AP vs BP) = 1.9, P = 0.038; OR(AP vs WP) = 2.4, P < 0.001]. After RP onset, AP and BP had a higher hazard to die than had WP [hazard ratio (HR) (AP) = 1.6, P = 0.011; HR(BP) = 2.1, P < 0.001].Conclusion. Compared with WP, and mostly independent of geographical location, AP have a faster and earlier disease onset with high prevalences of ATA, pulmonary hypertension and forced vital capacity impairment and higher mortality. BP had the fastest disease onset, a high prevalence of diffuse skin involvement and nominally the highest mortality

Teores de Micronutrientes (B, Cu, Fe, Mn E Zn) em espécies de Poaceae de uma área de Cerrado Maranhense

Conhecer a composição inorgânica dos vegetais tem sido cada vez mais importante, uma vez que estes vêm sendo largamente empregados em indústrias de alimentos, de cosméticos ou para aplicações medicinais. O objetivo desse trabalho foi fazer a determinação dos micronutrientes em espécies da família Poaceae, encontradas em uma área do Cerrado Maranhense.  Para isso, foram realizadas expedições de coletas sistematizadas, herborização e identificação das espécies vegetais e determinação da concentração de B, Cu, Fe, Mn e Zn, em diferentes espécies de Poaceae. Na área estudada foram identificadas 19 espécies da família Poaceae, distribuídas em 15 gêneros. Quanto as concentrações dos micronutrientes nas espécies vegetais, observou-se que as espécies analisadas apresentaram concentração de boro de 3 a 14 mg/kg, cobre de 1 a 13mg/kg,  ferro de 50 a 974 mg/kg, manganês de  47 a 415 mg/kg e  zinco de 16 a 170mg/kg. A maior concentração de ferro e zinco  foram determinada na Sporobolus indicus, enquanto que as espécies Setaria geniculata e Paspalum maritimum apresentaram maior concentração de boro e cobre respectivamente. Já na espécie Aristida longifolia foi determinada a menor concentração de boro manganês e zinco

Promoção de saúde com crianças da comunidade quilombola Custaneira/Tronco em Paquetá-PI

Este estudo objetiva apresentar um relato de experiência vivenciado pela equipe multiprofissional da Residência em Saúde da Família e Comunidade da Universidade Estadual do Piauí – UESPI, com o intuito de descrever atividades de promoção de saúde realizadas com crianças da Comunidade Quilombola Custaneira-Tronco. O relato é fruto das ações de educação em saúde e saúde bucal realizadas in locu na comunidade, que permitiram a aproximação, o engajamento e a troca de conhecimentos considerando assim, cada uma das crianças como atores importantes para fazer e promover saúde naquela comunidade. Conclui-se que há grande relevância em produzir saúde com o público infantil, visto a capacidade que esse grupo possui de assimilar e transmitir conhecimentos

GC-MS Chemical Characterization and Antibacterial Effect of the Essential oil of <i>Piper mosenii</i>

Commercialized mouthwashes are generally expensive for the most financially vulnerable populations. Thus, several studies evaluate the antimicrobial potential of herbal products, such as essential oils, to reduce the activity of microorganisms in the mouth. The objective of this research was to carry out the chemical characterization and antibacterial activity of the essential oil of Piper mosenii (EOPm), providing data that enable the development of a low-cost mouthwash formulation aimed at vulnerable communities. The analysis of the antibacterial potential and modulator of bacterial resistance was verified by the microdilution method to determine the minimum inhibitory concentration-MIC. The chemical components were characterized by gas chromatography coupled to mass spectrometry, where 23 chemical constituents were detected, with α-pinene, being the major compound. The EOPm showed a MIC ≥ 1024 µg/mL for all bacterial strains used in the tests. When the EOPm modulating activity was evaluated together with chlorhexidine, mouthwash and antibiotics against bacterial resistance, the oil showed a significant synergistic effect, reducing the MIC of the products tested in combination, in percentages between 20.6% to 96.3%. Therefore, it is recommended to expand the tests with greater variation of EOPm concentration and the products used in this research, in addition to the evaluation of toxicity and in vivo tests, seeking the development of a possible formulation of mouthwash accessible to the vulnerable population