4,243 research outputs found

    Subradiant states of quantum bits coupled to a one-dimensional waveguide

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    The properties of coupled emitters can differ dramatically from those of their individual constituents. Canonical examples include sub- and super-radiance, wherein the decay rate of a collective excitation is reduced or enhanced due to correlated interactions with the environment. Here, we systematically study the properties of collective excitations for regularly spaced arrays of quantum emitters coupled to a one-dimensional (1D) waveguide. We find that, for low excitation numbers, the modal properties are well-characterized by spin waves with a definite wavevector. Moreover, the decay rate of the most subradiant modes obeys a universal scaling with a cubic suppression in the number of emitters. Multi-excitation subradiant eigenstates can be built from fermionic combinations of single excitation eigenstates; such "fermionization" results in multiple excitations that spatially repel one another. We put forward a method to efficiently create and measure such subradiant states, which can be realized with superconducting qubits. These measurement protocols probe both real-space correlations (using on-site dispersive readout) and temporal correlations in the emitted field (using photon correlation techniques).Comment: 21 pages, 9 figure

    Global Communications Newsletter

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    Developmental Sex Differences in the Metabolism of Cardiolipin in Mouse Cerebral Cortex Mitochondria

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    Cardiolipin (CL) is a mitochondrial-specific phospholipid. CL content and acyl chain composition are crucial for energy production. Given that estradiol induces CL synthesis in neurons, we aimed to assess CL metabolism in the cerebral cortex (CC) of male and female mice during early postnatal life, when sex steroids induce sex-dimorphic maturation of the brain. Despite the fact that total amount of CL was similar, its fatty acid composition differed between males and females at birth. In males, CL was more mature (lower saturation ratio) and the expression of the enzymes involved in synthetic and remodeling pathways was higher, compared to females. Importantly, the sex differences found in CL metabolism were due to the testosterone peak that male mice experience perinatally. These changes were associated with a higher expression of UCP-2 and its activators in the CC of males. Overall, our results suggest that the perinatal testosterone surge in male mice regulates CL biosynthesis and remodeling in the CC, inducing a sex-dimorphic fatty acid composition. In male's CC, CL is more susceptible to peroxidation, likely explaining the testosterone-dependent induction of neuroprotective molecules such as UCP-2. These differences may account for the sex-dependent mitochondrial susceptibility after perinatal hypoxia/ischemia.Instituto de Investigaciones Bioquímicas de La Plat

    Developmental Sex Differences in the Metabolism of Cardiolipin in Mouse Cerebral Cortex Mitochondria

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    Cardiolipin (CL) is a mitochondrial-specific phospholipid. CL content and acyl chain composition are crucial for energy production. Given that estradiol induces CL synthesis in neurons, we aimed to assess CL metabolism in the cerebral cortex (CC) of male and female mice during early postnatal life, when sex steroids induce sex-dimorphic maturation of the brain. Despite the fact that total amount of CL was similar, its fatty acid composition differed between males and females at birth. In males, CL was more mature (lower saturation ratio) and the expression of the enzymes involved in synthetic and remodeling pathways was higher, compared to females. Importantly, the sex differences found in CL metabolism were due to the testosterone peak that male mice experience perinatally. These changes were associated with a higher expression of UCP-2 and its activators in the CC of males. Overall, our results suggest that the perinatal testosterone surge in male mice regulates CL biosynthesis and remodeling in the CC, inducing a sex-dimorphic fatty acid composition. In male's CC, CL is more susceptible to peroxidation, likely explaining the testosterone-dependent induction of neuroprotective molecules such as UCP-2. These differences may account for the sex-dependent mitochondrial susceptibility after perinatal hypoxia/ischemia.Instituto de Investigaciones Bioquímicas de La Plat

    Collaboration and Decision Making in Crisis Situations

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    [EN] Emergencies are critical situations that demand immediate action to avoid adverse consequences to life and property. Recent events around the world highlight the importance of the theme. A key challenge in Emergency Management is decision-making under time pressure, with an overload of unconfirmed, uncertain and conflicting information, including the management of many people, with distinct and possibly fluid roles, in different places. Collaboration in these settings is an interesting element, since emergency response generally involves multiple agencies and the public, which, having different views, protocols and priorities, must act in concert to handle the situation. In addition, an increasing amount of virtual information is necessary to inform and manage volunteers. The goal of this workshop is to identify and map the main challenges of collaboration in crisis situations, review current research methods and approaches to address them and address the lack of formal processes, structures, methodologies and tools.Adriana S Vivacqua is partially supported by CNPq grant 308425/2012-0 and FAPERJ grant E26/103.029/2012. Vaninha Vieira is partially supported by CNPq grant 490084/2013-3Vivacqua, AS.; Garcia, ACB.; Canos Cerda, JH.; Comes, M.; Vieira, V. (2016). Collaboration and Decision Making in Crisis Situations. ACM. 503-508. https://doi.org/10.1145/2818052.2855520S50350

    Information processing among high-performance managers

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    O propósito deste estudo foi avaliar o processamento da informação de 43 gestores empresariais de desempenho superior. No seu enquadramento teórico recorremos a três modelos: a Teoria dos Papéis Gerenciais de Henry Mintzberg, a Teoria do Processamento da Informação e o Modelo de Processo de Resposta ao Rorschach de John Exner. A ava-liação dos sujeitos recorreu ao método do Rorschach. Os resultados deste estudo mos-traram que esses gerentes são capazes de recolher dados, avaliá-los e estabelecer ran-kings de maneira adequada. Ao mesmo tempo, verifica-se que são capazes de ser objeti-vos e precisos na avaliação dos problemas. Este estilo de processamento de informação possibilita uma interpretação do mundo a partir de um modo de processamento ou de um estilo cognitivo, próprio e característico.The purpose of this study was to evaluate the information processing of 43 business managers with a professional superior performance. The theoretical framework consid-ers three models: the Theory of Managerial Roles of Henry Mintzberg, the Theory of In-formation Processing, and Process Model Response to Rorschach by John Exner. The participants have been evaluated by Rorschach method. The results show that these managers are able to collect data, evaluate them and establish rankings properly. At same time they are capable of being objective and accurate in the problems assessment. This information processing style permits an interpretation of the world around on basis of a very personal and characteristic processing way or cognitive style.Fundação para a Ciência e a Tecnologia (FCT), no âmbito do Fundo de Apoio à Comunidade Científica - Edição de Publicações Periódicas de Natureza Científica

    Análisis funcional de efectores candidatos de Podosphaera xanthii

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    Los oídios son patógenos biotrofos obligados que requieren células vivas para su desarrollo, por lo que deben eludir o inhibir las respuestas de defensa de la planta mediante la secreción de efectores para completar su ciclo de vida. El haustorio, estructura del hongo especializada en la toma de nutrientes, es también la vía de intercambio de factores con las células huésped. Hasta la fecha, son muy numerosos los efectores identificados en diversos hongos fitopatógenos, sin embargo, los efectores de los oídios están poco caracterizados todavía. En este trabajo hemos desarrollado un método para la identificación y el análisis de efectores candidatos de Podosphaera xanthii (ECP), el principal agente causal del oídio de las cucurbitáceas, mediante silenciamiento génico inducido por hospedador (HIGS) y la sobrexpresión de estos efectores en cotiledones de melón, utilizando para ello Agrobacterium tumefaciens. El silenciamiento de algunos de los ECP analizados provocó la acumulación en las células de la planta de compuestos relacionados con las respuestas de defensa como peróxido de hidrógeno (H2O2) y calosa, lo que sugiere un importante papel en el establecimiento de la infección. En concreto, ECPEc2 parece interferir específicamente con la formación de la papila, primera barrera de defensa de la planta que impide o ralentiza la penetración de la célula vegetal. En el caso de ECP5191, su silenciamiento se traduce un aumento del número de células que acumulaban H2O2 y calosa, así como una disminución en el número de puntos de penetración del hongo, observándose todo lo contrario cuando se sobrexpresa dicho efector. Además, la fusión traduccional CSEP5191-GFP ha permitido localizar este efector en los puntos de penetración y vesículas del haustorio del hongo.Este trabajo ha sido financiado por ayudas del Plan Nacional de I+D+I del anterior Ministerio de Ciencia e Innovación (AGL2010-21848-CO2-01), cofinanciado con fondos FEDER (UE)y una ayuda del Plan Propio de Investigación de la Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech
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