170 research outputs found
Supplementary data for article: StepanoviÄ, S.; AnÄelkoviÄ, L.; Zlatar, M.; AnÄelkoviÄ, K. K.; Gruden-PavloviÄ, M.; Swart, M. Role of Spin State and Ligand Charge in Coordination Patterns in Complexes of 2,6-Diacetylpyridinebis(Semioxamazide) with 3d-Block Metal Ions: A Density Functional Theory Study. Inorganic Chemistry 2013, 52 (23), 13415ā13423. https://doi.org/10.1021/ic401752n
Supporting information for: [https://doi.org/10.1021/ic401752n]Related to published version: [http://cherry.chem.bg.ac.rs/handle/123456789/1448
Crystal structures of mixed chloride-azide zinc (II) and chloride-isocyanate cadmium (II) complexes with the condensation product of 2-quinolinecarboxaldehyde and girardās reagent
The mixed chloride-azide [ZnL(N3)1.65Cl0.35] (1) and chloride-isocyanate [CdL(NCO)1.64Cl0.36] (2)
complexes have been prepared in the reactions of (E)-N,N,N-trimethyl-2-oxo-2-(2-(quinolin-2-
ylmethylene)hydrazinyl)ethan-1-aminium chloride (HLCl) and the corresponding Zn2+ and Cd2+
salts by adding the NaN3 and NaOCN, respectively. The structures of complexes 1 and 2 were
determined by X-ray crystallography
Sinteza i kristalna struktura 1,2,3,4-tetrahidro-9-aminoakridin-tetrahlorocinkata(II) monohidrata
In the reaction of ZnCl(2) with tacrine hydrochloride in water novel tetracoordinated (C(13)H(15)N(2))(2)[ZnCl(4)]-H(2)O complex was obtained and characterized by elemental analysis, molar conductivity and X-ray analysis. The complex crystallizes in the space group P-1 of the triclinic crystal system. The structure contains two crystallographically different molecules of protonated tacrine present as counter cations, the [ZnCl(4)](2-) complex anion and one water solvent molecule. The counter cations slightly differ in the puckering of the cyclohexene ring. The molecules of protonated tacrine are involved in different intermolecular hydrogen bonds. In the crystal, the hydrogen bonding generates a 3D assembly. In the crystal, pi center dot center dot center dot pi stacking interactions between the rings of protonated tacrine were evidenced. The [ZnCl(4)](2-) complex anion has a distorted tetrahedral geometry. Three out of the four Cl atoms are involved in intermolecular hydrogen bonding. The intermolecular H-bond interactions involving the Cl atoms affect the Zn-CI bond lengths.U reakciji ZnCl2 sa takrin-hidrohloridom u vodi, dobijen je novi tetrakoordinovani (C13H15N2)2[ZnCl4]?H2O kompleks koji je okarakterisan pomoÄu elementalne analize, molarne provodljivosti i rendgenske strukturne analize. Kompleks kristaliÅ”e u prostornoj grupi P?1 trikliniÄnog kristalnog sistema. Struktura sadrži dva kristalografski razliÄita molekula protonovanog takrina koji su prisutni kao kontra-katjoni, [ZnCl4]2 kompleksni anjon i molekul kristalne vode. Molekuli katjona se neznatno razlikuju u stepenu nabiranja cikloheksenovog prstena. Molekuli protonovanog takrina su ukljuÄeni u razliÄite intermolekulske vodoniÄne veze. Intermolekulsko vodoniÄno vezivanje u kristalu generiÅ”e 3D molekulski skup pi...pi interakcije izmeÄu prstenova protonovanog takrina su primeÄene u kristalu. [ZnCl4]2- ima distorgovanu tetraedarsku geometriju. Tri od Äetiri Cl atoma su ukljuÄena u intermolekulske vodoniÄne veze. Intermolekulske vodoniÄne interakcije koje ukljuÄuju Cl atome utiÄu na dužinu Zn-Cl veza
Crystal structures of mixed chloride-azide zinc (II) and chloride-isocyanate cadmium (II) complexes with the condensation product of 2-quinolinecarboxaldehyde and girardās reagent
The mixed chloride-azide [ZnL(N3)1.65Cl0.35] (1) and chloride-isocyanate [CdL(NCO)1.64Cl0.36] (2)
complexes have been prepared in the reactions of (E)-N,N,N-trimethyl-2-oxo-2-(2-(quinolin-2-
ylmethylene)hydrazinyl)ethan-1-aminium chloride (HLCl) and the corresponding Zn2+ and Cd2+
salts by adding the NaN3 and NaOCN, respectively. The structures of complexes 1 and 2 were
determined by X-ray crystallography
Supplementary data for article: StepanoviÄ, S.; AnÄelkoviÄ, L.; Zlatar, M.; AnÄelkoviÄ, K. K.; Gruden-PavloviÄ, M.; Swart, M. Role of Spin State and Ligand Charge in Coordination Patterns in Complexes of 2,6-Diacetylpyridinebis(Semioxamazide) with 3d-Block Metal Ions: A Density Functional Theory Study. Inorganic Chemistry 2013, 52 (23), 13415ā13423. https://doi.org/10.1021/ic401752n
Supporting information for: [https://doi.org/10.1021/ic401752n]Related to published version: [http://cherry.chem.bg.ac.rs/handle/123456789/1448
Visoki antioksidativni potencijal i mali toksiÄni efekat selenosemikarbazonskih kompleksa
Novel metal-based compounds with therapeutic potential have become the subject of intense investigations in inorganic chemistry and biomedical science. Recently, strong dose-dependent cytotoxic activities of selenosemicarbazone metal complexes against several human cancer cell lines were demonstrated. The aim of the present study was to investigate in vitro antioxidative potential of Ni(II), Cd(II) and Zn(II) selenosemicarbazone complexes. All three investigated complexes exhibited high 2,2'-azinobis(3-ethyl-benzothiazoline-6-sulphonic acid) radical cation (ABTS(center dot+)) scavenging capacity, comparable with ascorbic acid. In an acute toxicity study, administration of the compounds was performed orally to mice at single doses. The mice were observed for clinical signs, body weight effects and mortality for 14 days, after which they were sacrificed for gross organ necropsy. The body weight did not vary after administration, and the autoptic analysis failed to show appreciable macroscopic alterations of internal organs. Generally, the compounds exhibited low toxic effects as required for further in vivo therapeutic studies.Nova jedinjenja na bazi metala sa terapeutskim dejstvom postala su predmet istraživanja u neorganskoj hemiji i biomedicinskim naukama. Pokazana je jaka dozno-zavisna citotoksiÄna aktivnost kompleksa selenosemikarbazona na veÄem broju Äelijskih linija humanih Äelija kancera. Cilj rada je ispitivanje in vitro antioksidativnog dejstva selenosemikarbazonskih kompleksa nikla, cinka i kadmijuma. Sva tri ispitivana kompleksa pokazala su jaku antioksidativnu aktivnost prema ABTS radikalu, uporedivu sa aktivnoÅ”Äu askorbinske kiseline. Tokom ispitivanja akutne toksiÄnosti, jedinjenja su oralno davana miÅ”evima u pojedinaÄnim dozama i praÄeni su kliniÄki znaci, težina tela i mortalitet nakon 14 dana, a potom su životinje žrtvovane radi autopsije organa. Težina tela nije varirala nakon aplikacije. Generalno, jedinjenja su pokazala mali toksiÄni efekat Å”to i zahteva buduÄe in vivo terapeutsko ispitivanje
2,2 '-{1,1 '-[2,2 '-Oxalylbis(hydrazin-2-yl-1-ylidene)]diethylidyne}dipyridinium bis(perchlorate) dihydrate
The title salt, C(16)H(18)N(6)O(2)(2+)center dot 2ClO(4)(-)center dot 2H(2)O, was obtained unintentionally as a major product in the reaction of Zn(ClO(4))(2)center dot 6H(2)O with the N',N'(2)-bis[(1E)-1-(2-pyridyl)ethylidene]ethanedihydrazide (H(2)L) ligand. The (H(4)L)(2+) cation lies across a centre of inversion. The pyridiniumimine fragments of (H(4)L)(2+) adopt syn orientations. Intramolecular N-H center dot center dot center dot N and N-H center dot center dot center dot O hydrogen bonds lead to the formation of S(5) motifs. In the crystal, neighbouring cations are connected by pi-pi interactions between pyridinium units with a centroid-centroid distance of 3.600 (1) angstrom. Moreover, the crystal components are assembled into two-dimensional layers via N-H center dot center dot center dot O and O-H center dot center dot center dot O hydrogen bonds, with no direct hydrogen-bonding interactions between cations
Sinteza i karakterizacija nikal(II) i bakar(II) kompleksa sa polidentatnim dialkil ditiokarbaminskim ligandom 3-ditiokarboksi-3-aza-5-aminopentanoatom
Square planar complexes of Ni(II) and Cu(II) with potassium 3-dithiocarboxy-3-aza-5-aminopentanoate have been prepared by direct synthesis. The obtained neutral complexes were characterized by elemental analysis, magnetic susceptibility measurements, infrared and electronic spectra. The thermal behaviour of both the Ni(II) and Cu(II) complexes, and the ligand itself was investigated by DSC and TG.Direktnom sintezom izmeÄu nikal(II)- i bakar(II)- soli i kalijum 3-ditiokarboksi-3-aza-5-aminopentanoata nagraÄeni su odgovarajuÄi kompleksi kvadratno-planarne strukture. Izolovani neutralni kompleksi karakterisani su elementalnom analizom, infracrvenom i elektronskom apsorpcionom spektroskopijom, kao i merenjem magnetnih susceptibiliteta. TermiÄko ponaÅ”anje kompleksa i liganda ispitivano je primenom DSC i TG metoda
Supplementary data for article: FilipoviÄ, N. R.; Borna, M.; KlisuriÄ, O.; Pregelj, M.; JagodiÄ, M.; AnÄelkoviÄ, K. K.; TodoroviÄ, T. Synthesis, Characterization, and Thermal Behavior of Cu(II) and Zn(II) Complexes with (E)-2-[N-(1-Pyridin-2-Yl-Ethylidene)Hydrazino]Acetic Acid (AphaOH). Crystal Structure of [Zn-2(AphaO)(2)Cl-2]. Journal of Coordination Chemistry 2013, 66 (9), 1549ā1560. https://doi.org/10.1080/00958972.2013.786052
Supplementary material for: [https://doi.org/10.1080/00958972.2013.786052]Related to published version: [http://cherry.chem.bg.ac.rs/handle/123456789/1639
Sinteza I karakterizacija kompleksa cinka(II), paladijuma(II) I platine(II) sa 2ā-[1-(2-piridinil)etiliden]oksamohidrazidom - kristalna struktura bis {2ā-[1-(2-piridinil)etiliden]oksamohidrazido}cink(II) trihidrata
Complexes of Zn(II), Pd(II) and Pt(II) with 2'-[1-(2- pyridinyl)ethyhdene]oxamohydrazide (Hapsox) were synthesized and their structures were determined. All the complexes are of a neutral type with two apsox ligands coordinated to Zn(II) and one apsox ligand coordinated to Pd(II) or Pt(II). In each case. the polydentate was coordinated via pyridine and hydrazone nitrogens and alpha-oxyazine oxygen. forming an octahedral geometry around Zn(II). and a square planar one around Pd(II) and Pt(II). The structure determination was performed by IR. H-1-NMR and C-13-NMR spectroscopy, and for the Zn(II) complex by X-ray structure analysis.U ovom radu opisana je sinteza i strukturna karakterizacija kompleksa Zn(II) Pd(II) i Pt(II) sa 2ā-[1-(2-piridinil)etiliden]oksamohidrazidom (Hapsox). Sva tri dobijena kompleksa su neutralnog tipa sa dva koordinovana apsox liganda u sluÄaju kompleksa Zn(II), odnosno jednim apsox ligandom u sluÄaju Pd(II) i Pt(II) kompleksa. Koordinacija polidentata je u svim kompleksima ostvarena preko piridinskog azota, hidrazonskog azota i Ī±-oksiazinskog kiseonika gradeÄi oktaedarsku geometriju oko Zn(II), odnosno kvadratno planarnu geometriju oko Pd(II) i Pt(II).Potvrdu za ovakve strukture dobili smo iz IC 1H-NMR i 13C-NMR spektara, dok je za Zn(II) kompleks uraÄena i rendgenska strukturna analiza
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