Clinical profile and factors associated with microalbuminuria in type 1 diabetes mellitus in children and adolescents

Background: The aim of this study was to determine the pattern of clinical presentation and factor associated with microalbuminuria.Methods: Urinary albumin excretion of children and adolescents diagnosed with type 1 diabetes mellitus attending diabetic clinic of Katihar medical college hospital over a period of one year. Collected blood and urine samples were analysed for glycated haemoglobin, cholesterol, triglycerides, and for 12 hour urinary albumin concentration. Blood pressures were recorded and clinical data collected.Results: During the study period 215 patients were diagnosed with type1 DM. Out of 215, fourty-three patients (20%) had persistent microalbuminuria. Factor associated with microalbuminuria in diabetic patients include duration of diabetes mellitus, higher blood pressure, higher cholesterol and triglyceride levels.Conclusion: Type 1 DM is treatable and testing is acceptable and accessible to the patients. As microalbuminuria is an early microvascular complications, it is highly recommended to screen all diabetic patients for the incidence of microalbuminuria and modifiable risk factors like dyslipidemia at the onset and then yearly assessment. Efforts need to be intensified in education of health workers and population at large for quick presentation and prompt diagnosis in order to predict overt diabetic nephropathy and also to prevent its progression.

Septo-optic dysplasia with lissencephaly

Septo –optic dysplasia with lissencephaly rarely occurs simultaneously. We describe such a patient presenting with absent visual fixation, mild developmental delay, ophthalmological examination revealed small pale optic disc with typical double rim and B/L optic nerve hypoplasia with CT scan finding of lissencephaly and absence of septum pellucidum. The above finding leads to the diagnosis of septo-optic dysplasia with lissencephaly

Simultaneous Conjugacy Classes of Finite pp-groups of rank ≤5\leq 5

For a finite group $G$, we consider the problem of counting simultaneous conjugacy classes of $n$-tuples and simultaneous conjugacy classes of commuting $n$-tuples in $G$. Let $\alpha_{G,n}$ denote the number of simultaneous conjugacy classes of $n$-tuples, and $\beta_{G,n}$ the number of simultaneous conjugacy classes of commuting $n$-tuples in $G$. The generating functions $A_G(t) = \sum_{n\geq 0} \alpha_{G,n}t^n,$ and $B_G(t) = \sum_{n\geq 0} \beta_{G,n}t^n$ are rational functions of $t$. This paper concern studied of normalized functions $A_G(t/|G|)$ and $B_G(t/|G|)$ for finite $p$-groups of rank at most $5$.Comment: arXiv admin note: substantial text overlap with arXiv:1905.0795

Thermal energy storage based solar drying systems: a review

Solar dryer based on thermal energy storage materials is quite effective for continuously drying agriculture and food products at steady state in the temperature range (40 °C–60 °C). Such dryers have globally become a potential viable substitute to the solar dryers based on fossil fuel, due to the utilization of clean energy resources and cost-effectiveness. Storage materials utilized in these dryers can store energy during the sunshine hour and deliver the stored energy during off-sunshine. It reduces the existing load on the gap between energy demand and supply, hence plays a vital role in energy sustainability. A number of studies have been done in last few decades for drying agriculture and food products with a solar dryer based on thermal energy storage concept. This paper mainly presents a review on the important contributions made so far in the field of solar drying systems based on the thermal energy storage medium, with a focus on recent updates in thermal energy storage technology available in terms of materials capable of storing heat as sensible and latent heat

Prescription auditing based on World Health Organization (WHO) prescribing indicators in a teaching hospital in North India

Background: Prescription writing is an important means of therapeutic intervention by the doctor and reflects his approach towards safe prescribing. Complacency in prescribing results in errors which can even cause adverse effects. These errors can be detected through a prescription audit. We undertook this study to audit the out-patient department (OPD) prescriptions for completeness of prescription format, legibility and against the World Health Organization (WHO) prescribing indicators recommended to investigate rational use of drugs. Methods: OPD prescriptions were photographed from the pharmacy of a teaching hospital over a period of three months and 1274 prescriptions were audited. Prescriptions were evaluated for completeness of prescription format while legibility was graded as grade 1, 2 and 3. Prescriptions were also analyzed on the five WHO prescribing indicators. Results: An average of 4.02 ± 2.23 drugs were prescribed per prescription of which 39.01% were antibiotics. Though 79.2% drugs were prescribed from the Essential Drug List, none was prescribed by the generic name. Rate of injection use was 7.54% in our study. Registration number of the doctor was absent in 100% of the prescriptions. Errors such as omitting the mention of allergy status, follow-up advice and directions of use were common. Almost 8% prescriptions were illegible (grade3) and 66.8% were legible with difficulty (grade 2). Conclusion: Majority of the prescriptions were incomplete and poly-pharmacy was evident in our study. Regular auditing and feedback is necessary for imbibing safe prescribing practices. Doctors need to be made aware about the errors and the recommended guidelines

Chondroblastic osteosarcoma of breast in a case of phyllodes tumour with recurrence, a rare case report

Introduction: Primary extra osseous osteogenic sarcomas have been reported in many tissues of the body but their occurrence in the breast is extremely rare. It can arise as a result of osseous metaplasia in a pre-existing benign or malignant neoplasm of the breast. Case presentation: A 24 year-old young lady was diagnosed to have mass in right breast.Tru cut biopsy showed it was malignant phyllodes tumour. There was no distant metastasis or any axillary lymph nodes palpable. Simple mastectomy was done. The histology report of biopsy showed a malignant phyllodes with chondrosarcomatous differentiation an myxoid changes. She was given 6 cycles of chemotherapy. There was recurrence after 6 months of surgery. Then radical mastectomy with latissimus dorsi musculocutaneous flap was used to cover the anterior chest wall defect. Sections from the mastectomy specimen confirmed the diagnosis of chondroblastic osteosarcoma. Axillary nodes free of tumour cells. Now the patient again came with recurrence after 5 months, and disseminate subcutaneous nodules. Conclusion: A diagnosis of chondroblastic osteosarcoma of the breast was made based on histology report and after excluding any osteogenic sarcoma arising from underlying ribs and sternum. It is a very rare disease with only few case reports in literature

Effects of an integrated yoga program in modulating psychological stress and radiation-induced genotoxic stress in breast cancer patients undergoing radiotherapy

10.1177/1534735407306214Integrative Cancer Therapies63242-25