Visualizing the search results to improve access to library resources

The main purpose of this research is to calculate performance of visualization methods through calculating the time lapse between search results display and access to the item and analyze the results statistically. In this study, three methods have been considered to help users: Viewing the book place in three-dimention, showing location of the book by color symbols and using graphic symbols

Organizational Knowledge Mapping Based on Library Information System

One of the most popular techniques for identifying knowledge in organizations is knowledge mapping. It can help decision makers to better understand the knowledge flow within the organizations. Mapping organizations knowledge, especially in research institutes, has attracted much attention from senior managements in recent years. Libraries, among the most important parts of research institutes, have a significant role in scientific advances. Due to this important role, many knowledge operations take place in collaboration with libraries. All of library transactions including users borrowing and returning logs and also books metadata are recorded in library information systems. Users' transaction logs are rich resources to extract information about knowledge operations in an organization. In this paper we propose a new methodology for drawing knowledge map, based on library information system logs. Our proposed methodology contains five steps including data collection and making data warehouse, data preprocessing and refinement, applying knowledge mapping algorithm for extracting input data for mapping, drawing knowledge map and finally analyzing the results. According to this methodology, we have drawn the IRANDOC knowledge map emphasizing interdisciplinary domains based on library information system users’ logs. IRANDOC knowledge map shows most studied subjects and also interrelation between them which are invaluable source of knowledge for IRANDOC decision makers in order to initiate research projects

Pyocyanin restricts social cheating in <em>Pseudomonas aeruginos</em>a.

Quorum sensing (QS) in Pseudomonas aeruginosa coordinates the expression of virulence factors, such as exoproteases and siderophores, that are public goods utilized by the whole population of bacteria, regardless of whether they invested or not in their production. These public goods can be used by QS defective mutants for growth, and since these mutants do not contribute to public goods production, they are considered social cheaters. Pyocyanin is a phenazine that is a toxic, QS-controlled metabolite produced by P. aeruginosa. It is a redox-active compound and promotes the generation of reactive oxygen species; it also possesses antibacterial properties and increases fitness in competition with other bacterial species. Since QS-deficient individuals are less able to tolerate oxidative stress, we hypothesized that the pyocyanin produced by the wild-type population could promote selection of functional QS systems in this bacterium. Here, we demonstrate, using competition experiments and mathematical models, that, indeed, pyocyanin increases the fitness of the cooperative QS-proficient individuals and restricts the appearance of social cheaters. In addition, we also show that pyocyanin is able to select QS in other bacteria such as Acinetobacter baumannii

Table_1_Pyocyanin Restricts Social Cheating in Pseudomonas aeruginosa.docx

<p>Quorum sensing (QS) in Pseudomonas aeruginosa coordinates the expression of virulence factors, such as exoproteases and siderophores, that are public goods utilized by the whole population of bacteria, regardless of whether they invested or not in their production. These public goods can be used by QS defective mutants for growth, and since these mutants do not contribute to public goods production, they are considered social cheaters. Pyocyanin is a phenazine that is a toxic, QS-controlled metabolite produced by P. aeruginosa. It is a redox-active compound and promotes the generation of reactive oxygen species; it also possesses antibacterial properties and increases fitness in competition with other bacterial species. Since QS-deficient individuals are less able to tolerate oxidative stress, we hypothesized that the pyocyanin produced by the wild-type population could promote selection of functional QS systems in this bacterium. Here, we demonstrate, using competition experiments and mathematical models, that, indeed, pyocyanin increases the fitness of the cooperative QS-proficient individuals and restricts the appearance of social cheaters. In addition, we also show that pyocyanin is able to select QS in other bacteria such as Acinetobacter baumannii.</p

Data_Sheet_1_Pyocyanin Restricts Social Cheating in Pseudomonas aeruginosa.PDF

<p>Quorum sensing (QS) in Pseudomonas aeruginosa coordinates the expression of virulence factors, such as exoproteases and siderophores, that are public goods utilized by the whole population of bacteria, regardless of whether they invested or not in their production. These public goods can be used by QS defective mutants for growth, and since these mutants do not contribute to public goods production, they are considered social cheaters. Pyocyanin is a phenazine that is a toxic, QS-controlled metabolite produced by P. aeruginosa. It is a redox-active compound and promotes the generation of reactive oxygen species; it also possesses antibacterial properties and increases fitness in competition with other bacterial species. Since QS-deficient individuals are less able to tolerate oxidative stress, we hypothesized that the pyocyanin produced by the wild-type population could promote selection of functional QS systems in this bacterium. Here, we demonstrate, using competition experiments and mathematical models, that, indeed, pyocyanin increases the fitness of the cooperative QS-proficient individuals and restricts the appearance of social cheaters. In addition, we also show that pyocyanin is able to select QS in other bacteria such as Acinetobacter baumannii.</p

Presentation_1_Pyocyanin Restricts Social Cheating in Pseudomonas aeruginosa.PPTX

<p>Quorum sensing (QS) in Pseudomonas aeruginosa coordinates the expression of virulence factors, such as exoproteases and siderophores, that are public goods utilized by the whole population of bacteria, regardless of whether they invested or not in their production. These public goods can be used by QS defective mutants for growth, and since these mutants do not contribute to public goods production, they are considered social cheaters. Pyocyanin is a phenazine that is a toxic, QS-controlled metabolite produced by P. aeruginosa. It is a redox-active compound and promotes the generation of reactive oxygen species; it also possesses antibacterial properties and increases fitness in competition with other bacterial species. Since QS-deficient individuals are less able to tolerate oxidative stress, we hypothesized that the pyocyanin produced by the wild-type population could promote selection of functional QS systems in this bacterium. Here, we demonstrate, using competition experiments and mathematical models, that, indeed, pyocyanin increases the fitness of the cooperative QS-proficient individuals and restricts the appearance of social cheaters. In addition, we also show that pyocyanin is able to select QS in other bacteria such as Acinetobacter baumannii.</p