856 research outputs found
Relativistic Images in Randall-Sundrum II Braneworld Lensing
In this paper, we explore the properties of gravitational lensing by black
holes in the Randall-Sundrum II braneworld. We use numerical techniques to
calculate lensing observables using the Tidal Reissner-Nordstrom (TRN) and
Garriga-Tanaka metrics to examine supermassive black holes and primordial black
holes. We introduce a new way tp parameterize tidal charge in the TRN metric
which results in a large increase in image magnifications for braneworld
primordial black holes compared to their 4 dimensional analogues. Finally, we
offer a mathematical analysis that allows us to analyze the validity of the
logarithmic approximation of the bending angle for any static, spherically
symmetric metric. We apply this to the TRN metric and show that it is valid for
any amount of tidal charge.Comment: 13 pages, 3 figures; Accepted for Publication in Physical Review
Expectations of reward and efficacy guide cognitive control allocation
The amount of mental effort we invest in a task is influenced by the reward we can expect if we perform that task well. However, some of the rewards that have the greatest potential for driving these efforts are partly determined by factors beyond ones control. In such cases, effort has more limited efficacy for obtaining rewards. According to the Expected Value of Control theory, people integrate information about the expected reward and efficacy of task performance to determine the expected value of control, and then adjust their control allocation (i.e., mental effort) accordingly. Here we test this theorys key behavioral and neural predictions. We show that participants invest more cognitive control when this control is more rewarding and more efficacious, and that these incentive components separately modulate EEG signatures of incentive evaluation and proactive control allocation. Our findings support the prediction that people combine expectations of reward and efficacy to determine how much effort to invest
Strong Gravitational Lensing by Sgr A*
In recent years, there has been increasing recognition of the potential of
the galactic center as a probe of general relativity in the strong field. There
is almost certainly a black hole at Sgr A* in the galactic center, and this
would allow us the opportunity to probe dynamics near the exterior of the black
hole. In the last decade, there has been research into extreme gravitational
lensing in the galactic center. Unlike in most applications of gravitational
lensing, where the bending angle is of the order of several arc seconds, very
large bending angles are possible for light that closely approaches a black
hole. Photons may even loop multiple times around a black hole before reaching
the observer. There have been many proposals to use light's close approach to
the black hole as a probe of the black hole metric. Of particular interest is
the property of light lensed by the S stars orbiting in the galactic center.
This paper will review some of the attempts made to study extreme lensing as
well as extend the analysis of lensing by S stars. In particular, we are
interested in the effect of a Reissner-Nordstrom like 1/r^2 term in the metric
and how this would affect the properties of relativistic images.Comment: 13 pages, 9 figures. Submitted as invited review article for the GR19
issue of CQ
Self-Control in Cyberspace: Applying Dual Systems Theory to a Review of Digital Self-Control Tools
Many people struggle to control their use of digital devices. However, our
understanding of the design mechanisms that support user self-control remains
limited. In this paper, we make two contributions to HCI research in this
space: first, we analyse 367 apps and browser extensions from the Google Play,
Chrome Web, and Apple App stores to identify common core design features and
intervention strategies afforded by current tools for digital self-control.
Second, we adapt and apply an integrative dual systems model of self-regulation
as a framework for organising and evaluating the design features found. Our
analysis aims to help the design of better tools in two ways: (i) by
identifying how, through a well-established model of self-regulation, current
tools overlap and differ in how they support self-control; and (ii) by using
the model to reveal underexplored cognitive mechanisms that could aid the
design of new tools.Comment: 11.5 pages (excl. references), 6 figures, 1 tabl
The Effects of Dietary Linoleic Acid and Hydrophilic Antioxidants on Basal, Peak, and Sustained Metabolism in Flightâtrained European Starlings
Dietary micronutrients have the ability to strongly influence animal physiology and ecology. For songbirds, dietary polyunsaturated fatty acids (PUFAs) and antioxidants are hypothesized to be particularly important micronutrients because of their influence on an individual\u27s capacity for aerobic metabolism and recovery from extended bouts of exercise. However, the influence of specific fatty acids and hydrophilic antioxidants on wholeâanimal performance remains largely untested. We used diet manipulations to directly test the effects of dietary PUFA, specifically linoleic acid (18:2n6), and anthocyanins, a hydrophilic antioxidant, on basal metabolic rate (BMR), peak metabolic rate (PMR), and rates of fat catabolism, lean catabolism, and energy expenditure during sustained flight in a wind tunnel in European starlings (Sturnus vulgaris). BMR, PMR, energy expenditure, and fat metabolism decreased and lean catabolism increased over the course of the experiment in birds fed a high (32%) 18:2n6 diet, while birds fed a low (13%) 18:2n6 diet exhibited the reverse pattern. Additionally, energy expenditure, fat catabolism, and flight duration were all subject to dietâspecific effects of wholeâbody fat content. Dietary antioxidants and dietârelated differences in tissue fatty acid composition were not directly related to any measure of wholeâanimal performance. Together, these results suggest that the effect of dietary 18:2n6 on performance was most likely the result of the signaling properties of 18:2n6. This implies that dietary PUFA influence the energetic capabilities of songbirds and could strongly influence songbird ecology, given their availability in terrestrial systems
microRNA-184 induces a commitment switch to epidermal differentiation
miR-184 is a highly evolutionary conserved microRNA (miRNA) from fly to human. The importance of miR-184 was underscored by the discovery that point mutations in miR-184 gene led to corneal/lens blinding disease. However, miR-184-related function in vivo remained unclear. Here, we report that the miR-184 knockout mouse model displayed increased p63 expression in line with epidermal hyperplasia, while forced expression of miR-184 by stem/progenitor cells enhanced the Notch pathway and induced epidermal hypoplasia. In line, miR-184 reduced clonogenicity and accelerated differentiation of human epidermal cells. We showed that by directly repressing cytokeratin 15 (K15) and FIH1, miR-184 induces Notch activation and epidermal differentiation. The disease-causing miR-184C57U mutant failed to repress K15 and FIH1 and to induce Notch activation, suggesting a loss-of-function mechanism. Altogether, we propose that, by targeting K15 and FIH1, miR-184 regulates the transition from proliferation to early differentiation, while mis-expression or mutation in miR-184 results in impaired homeostasis
A Differential Effect of E. coli Toxin-Antitoxin Systems on Cell Death in Liquid Media and Biofilm Formation
Toxin-antitoxin (TA) modules are gene pairs specifying for a toxin and its antitoxin and are found on the chromosomes of many bacteria including pathogens. Here we report how each of five such TA systems in E. coli affect bacterial cell death differently in liquid media and during biofilm formation. Of all these systems, only the TA system mazEF mediated cell death both in liquid media and during biofilm formation. At the other extreme, as our results have revealed here, the TA system dinJ-YafQ is unique in that it is involved only in the death process during biofilm formation. Cell death governed by mazEF and dinJ-YafQ seems to participate in biofilm formation through a novel mechanism
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