217 research outputs found

    Assessment on Quantum skills of employed nurses in Ayatollah Kashani and Hajar Hospitals of Shahrekord city in 2015

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    Background and aims: Skills of nurses due to their professional sensitivity and their relation in public health should continually be monitored. Therefore, the present study was carried out to determine the Quantum skills of nurses employed in Ayatollah Kashani and Hajar hospitals of Shahrekord city. Methods: This cross- sectional descriptive - analytic study was performed in 2016 in Ayatollah Kashani and Hajar hospitals of Shahrekord city. One hundred nurses selected by stratified random sampling and data were collected using a valid questionnaire. The data were analyzed by SPSS 21 software through Chi-Square and independent t-test at the significant level of P<0.05. Results: The Grade Point Average (GPA) of each septel quantum skills including seeing, thinking, feeling, knowing, acting, trusting and being skills in nurses were significantly higher than criterion mean score (P>0.05). Totally, the GPA of nurses’ quantum skills was 136.69±10.07 that had a significant differenc compared to Criterion Mean Score (CMS=105) (P<0.001). Conclusion: According to the rathered results, it can be stated that nurses employed in Ayatollah Kashani and Hajar hospitals of Shahrekor city had a desirable status in the septel quantum skills

    β-catenin and transforming growth factor β have distinct roles regulating fibroblast cell motility and the induction of collagen lattice contraction

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    <p>Abstract</p> <p>Background</p> <p>β-catenin and transforming growth factor β signaling are activated in fibroblasts during wound healing. Both signaling pathways positively regulate fibroblast proliferation during this reparative process, and the effect of transforming growth factor β is partially mediated by β-catenin. Other cellular processes, such as cell motility and the induction of extracellular matrix contraction, also play important roles during wound repair. We examined the function of β-catenin and its interaction with transforming growth factor β in cell motility and the induction of collagen lattice contraction.</p> <p>Results</p> <p>Floating three dimensional collagen lattices seeded with cells expressing conditional null and stabilized β-catenin alleles, showed a modest negative relationship between β-catenin level and the degree of lattice contraction. Transforming growth factor β had a more dramatic effect, positively regulating lattice contraction. In contrast to the situation in the regulation of cell proliferation, this effect of transforming growth factor β was not mediated by β-catenin. Treating wild-type cells or primary human fibroblasts with dickkopf-1, which inhibits β-catenin, or lithium, which stimulates β-catenin produced similar results. Scratch wound assays and Boyden chamber motility studies using these same cells found that β-catenin positively regulated cell motility, while transforming growth factor β had little effect.</p> <p>Conclusion</p> <p>This data demonstrates the complexity of the interaction of various signaling pathways in the regulation of cell behavior during wound repair. Cell motility and the induction of collagen lattice contraction are not always coupled, and are likely regulated by different intracellular mechanisms. There is unlikely to be a single signaling pathway that acts as master regulator of fibroblast behavior in wound repair. β-catenin plays dominant role regulating cell motility, while transforming growth factor β plays a dominant role regulating the induction of collagen lattice contraction.</p

    A study on the qualitative and quantitative traits of barley (Hordeum vulgare L.) and narbon vetch (Vicia narbonensis L.) in intercropping and sole cropping system under the interference and control of weeds in dry land farming...

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    In order to investigate the effect of intercropping and sole cropping of barley and narbon vetch with weed control and interference conditions on their qualitative and quantitative traits, this experiment was conducted with 5 levels of intercropping (seed contribution): sole cropping of narbon vetch, 75:25 (narbon vetch : barley), 50:50, 25:75 and sole cropping of barley. Two levels of weed control and weed interference in row replacement series system in the form of factorial was designed with Randomized Complete Blocked Design (RCBD) in 3 replications in the College of Agriculture, Lorestan University, from 2006 - 2007. Results showed that the interaction of weed and the contribution of complementary components of intercropping has significant effect on crude protein (CP) and neutral detergent fibers (NDF) content in barley. Maximum CP and NDF were related to sole cropping of barley (infected by weeds), and maximum CP with minimum NDF were related to (narbon vetch: barley) 75:25 treatment, so that 31% of CP decreased in sole cropping of barley (infected by weeds) when compared with 75:25 combination. NDF percentage in sole cropping increased to 16.6%, therefore 25:75 (narbon vetch: barley) combination was better than the others. So, in order to get proper percentage of protein and digestibility of forage for livestock, 75:25 (infected by weeds) combination is better, especially the combination of 25:75 (infected by weeds), due to its high protein content. The highest and lowest dry forage production of barley were related to its sole cropping (a control which is equal to 3.75 t/ha) and 75:25 barley (infected by weeds that are equal to 1.59 t/ha), respectively.Keywords: Qualitative and quantitative, barley, narbon vetch, weed, dry lan

    Correlation of waist to hip ratio and intra abdominal injury after blunt trauma

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    زمینه و هدف: تروما یکی از شایع ترین علل مراجعات اورژانس است. حدود 7 تا 10 از مرگ و میر ناشی از تروما به دنبال ضایعات داخل شکمی اتفاق می افتد. به نظر می رسد که نسبت بالاتر دور شکم به لگن بتواند اثر محافظتی در کاهش احتمال آسیب های داخل شکمی ایفا کند. مطالعه حاضر به بررسی ارتباط میزان وقوع آسیب های شکمی ناشی از ترومای بلانت با نسبت دور شکم به لگن پرداخته است. روش بررسی: در این مطالعه توصیفی-تحلیلی 222 نفر از مبتلایان ترومای بلانت شکمی مراجعه کننده به اورژانس بیمارستان امام حسین (ع) تهران از جهت اطلاعات دموگرافیک، نسبت دور شکم به لگن و نهایتاً ارتباط آن با پیامدهای کلینیکی، پاراکلینیکی و تصویربرداری مورد بررسی قرار گرفتند. آزمون های کای دو و فیشر جهت آنالیز داده ها استفاده شد. یافته ها: اطلاعات دموگرافیک نشان داد متوسط سن مبتلایان 2/14 ± 7/28 سال و 8/74 از آنان مرد بودند. اقدامات آزمایشگاهی و تصویربرداری برای این سری از بیماران، تنها برای 13 نفر (5) شواهدی واضح از آسیب احشاء و ارگان های داخل شکمی را نشان داد. در هر دو جنس هیچ گونه ارتباط معنی داری بین نسبت دور شکم به لگن با میزان وقوع آسیب های شکمی بر اساس نتایج نهایی حاصل از سونوگرافی، سی تی اسکن، آنالیز ادراری و لاپاراتومی وجود نداشت(05/0 P>). نتیجه گیری: به نظر می رسد ارتباطی بین نسبت دور شکم به لگن با احتمال آسیب شکمی به دنبال ترومای بلانت وجود نداشته باشد اما اظهار نظر قطعی در این مورد نیاز به مطالعات بیشتر دارد

    Gene Polymormisms and Prostate Cancer: A Systematic Review

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    Introduction: The prostate is a gland that surrounds men's urethra and helps to produce semen. In developed countries, prostate cancer (PCa.) is the second most common and lethal disease in men. Hereditary history of PCa. is a major contributor to this cancer? While a number of genetic and molecular changes have been reported in PCa, the general picture of the genetic aberrations is needed in Iranian population.Methods: In this study, a literature search from Jan. 2000 to June 2018 was performed through the PubMed, Google Scholar, Scopus, Web of Science, IranMedex, MEDLIB, IranDoc and Scientific Information databases using the keywords “genetic polymorphisms”, “prostate cancer”, “Iranian, and compare with regional and international population”.Results: The results revealed that several genome-wide association studies (such as rs2070744 and rs1799983 in the eNOS, rs243865 in the MMP2, rs1902023 in the UGT2B15, rs266882 in the PSA, rs10625775443 in the GNB3, rs 1800682 in the FAS, rs12052398 and rs13393577 in the ERBB4, rs181133 in the MTHFR, rs 1805087 in the MTR, rs1805355 in the MSH3, (rs60271534 in the CYP19, rs2234693 and rs9340799 in the ER-a, rs4986938 and rs1256049 in the ER-b) and single-nucleotide polymorphisms in important pathways (such as angiogenesis, androgen receptor binding site, cell signaling, folate metabolism, DNA repair, hormone synthesis and metabolism polymorphisms ) involved in prostate cancer occurrence and mechanism could serve as candidate biomarkers for the detection of PCa. The most important results of the all studied articles is summarized in Table 1 and 2.Conclusion: Several studies have been conducted on the family history of PCa. The main reason for this gathering is to inherit the involved genes. Additional studies are required to decipher precisely the gene combinations and personalize the management of prostate cancer. This article is the first comprehensive overview of genetic investigations of gene polymorphisms on PCa. in Iran.

    The Effect of an Effective Coping Styles Training Program on Coping Strategies for Stress in Nurses Working in Clinical Departments Dealing with COVID-19 in Iran

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    Background: The prevalence of COVID-19 has caused stress, especially among nurses. On the other hand, the use of effective coping styles during the COVID crisis reduces stress in individuals.Aim: The present study was conducted with aim to investigate the effect of coping styles training program on coping strategies for stress in nurses.Method: This experimental study was conducted on nurses working in COVID-19 departments in April 2021. After obtaining informed consent, 80 participants were randomly divided into intervention and control groups. In the intervention group, training sessions were held as webinars for 3 sessions, each lasting 2 hours over three weeks. The Stress Coping Styles Questionnaire designed by Endler and Parker was completed by participants before and after the intervention. Data were analyzed by SPSS software (version 16) and one-way analysis of variance and paired t-test. p<0.05 was considered statistically significant.Results: After implementing the intervention, problem-focused coping styles increased among nurses working in COVID departments, while emotion-focused and avoidance-focused coping styles decreased after training sessions.Implications for Practice: Training the stress coping methods can lead to effective use of coping styles during crises such as COVID-19 among nurses working in COVID departments

    The impact of a 360° virtual tour of the college environment on the anxiety of newly arrived students during the COVID-19 pandemic

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    Background: University education has been held virtually during the COVID-19 pandemic. However, students were confused and anxious while attending college, both because they were exposed to a new environment and fearful of coronavirus infection.Objectives: The purpose of this study was to investigate the effect of a 360° virtual tour of the college physical environment on the anxiety of newly arrived students during the COVID-19 pandemic.Methods: This single-blind, randomized, controlled trial was conducted between January and February 2021, with 80 nursing, midwifery, and surgical technology students from the Faculty of Nursing and Midwifery, Isfahan University of Medical Sciences, Isfahan, Iran. Students were randomly allocated into an intervention group and a control group, each with 40 students. Students in the intervention group received a 360° virtual tour of the college physical environment to be familiarized with the college environment. Students in the control group, on the other hand, were personally familiarized with the physical environment of the college. Students' anxiety levels were measured before and after the intervention using the Spielberger State-Trait Anxiety Inventory (STAI). Independent samples t-test, paired t-test, and chi-square test were used to analyze the data.Results: The mean anxiety score in the intervention group decreased from 48.2±2.66 to 37.7±3.03 after the intervention (P<0.001). However, the mean anxiety score did not change significantly in the control group (P=0.59).Conclusion: A 360° virtual tour can reduce the anxiety of newly arrived students before entering the college environment

    The effects of two surgical gowning and gloving methods on the extent of contamination of surgical team members' gowns and gloves: A single-blind controlled trial

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    Background: The method used to wear the surgical gown and gloves has a critical role in the extent of surgical site contamination.Objectives: The purpose of this study was to compare the effect of gown and gloves wearing in the integrated and closed methods on the extent of contamination of surgical team members' gowns and gloves. Methods: A single-blind controlled trial was conducted with 70 eligible surgical staff who were randomly assigned to two groups of 35. The intervention group wore sterile, integrated gown-glove units, whereas the control group wore separate gowns and gloves using the closed technique. Glitterbug fluorescent powder was used to measure contamination. An ultraviolet flashlight was used to make the Glitterbug powder visible. Participants in both groups wore their gowns and gloves after dipping their hands in fluorescent powder. After one hour of the surgery, the gowns and gloves were removed from the body, a mobile phone was used to take photos of the areas containing powder, and ImageJ software was used to measure the area of contamination. The independent samples t-tests and chi-square test were used to analyze the data.Results: The contaminated area of gloves was 0.06±0.24 mm2 for the integrated gown-glove unit method and 2.26± 5.87 mm2 for the closed gown and gloves wearing method (P= 0.03). The contaminated area of the gown was zero for the integrated method and 3.06±7.57 mm2 for the closed method (P= 0.02).Conclusion: The extent of contamination was less when using the integrated gown-glove unit than the closed method. The surgical staff are recommended to use integrated gown-glove units to reduce the risk of contamination of gowns and gloves used for surgery
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