1,387 research outputs found
The Initial Mass Functions in the Super-Star-Clusters NGC 1569A and NGC 1705-1
I use recent photometric and stellar velocity dispersion measurements of the
super-star-clusters (SSCs) NGC 1569A and NGC 1705-1 to determine their
present-day luminosity/mass (L_V/M) ratios. I then use the inferred L_V/M
ratios, together with population synthesis models of evolving star-clusters, to
constrain the initial-mass-functions (IMFs) in these objects.
I find that (L_V/M)_solar=28.9 in 1569A, and (L_V/M)_solar=126 in 1705-1. It
follows that in 1569A the IMF is steep with alpha~2.5 for m**(-alpha)dm IMFs
which extend to 0.1 M_sun. This implies that most of the stellar mass in 1569A
is contained in low-mass (< 1 M_sun) stars. However, in 1705-1 the IMF is
either flat, with alpha<2$, or it is truncated at a lower mass-limit between 1
and 3 M_sun.
I compare the inferred IMFs with the mass functions (MFs) of Galactic
globular clusters. It appears that 1569A has a sufficient reservoir of low-mass
stars for it to plausibly evolve into an object similar to Galactic globular
clusters. However, the apparent deficiency of low-mass stars in 1705-1 may make
it difficult for this SSC to become a globular cluster. If low-mass stars do
dominate the cluster mass in 1705-1, the large L_V/M ratio in this SSC may be
evidence that the most massive stars have formed close to the cluster cores.Comment: ApJ, in press. 19 Pages, Latex; [email protected]
Nanoparticle formation of chitosan induced by 4-sulfonatocalixarenes: utilization for alkaloid encapsulation
Spontaneous formation of positively charged nanoparticles was observed upon mixing more than stoichiometric amount of chitosan with 4-sulfonatocalix[8]arene (SCX8) in acidic solution. The particle size did not change with SCX8 concentration, polymer chain length, and the degree of deacetylation at 0.002 ≤ SCX8/chitosan ≤0.043 molar ratios in 0.01 M HCl. However, larger aggregates were produced when chitosan concentration was increased. The most stable nanoparticles with 160 nm diameter and narrow size distribution were obtained at pH 4 using low molecular weight chitosan. These particles encapsulated coralyne with more than 90 % entrapment efficiency and 15 % loading capacity. A loading ratio of [coralyne]/[SCX8] = 1.7 was achieved without any stability loss. 4-Sulfonatocalix[4]arene induced the formation of slightly smaller nanoparticles than its homologs comprising 6 or 8 phenol units. © 2016, Springer-Verlag Berlin Heidelberg
Ionizing Photon Emission Rates from O- and Early B-type Stars and Clusters
We present new computations of the ionizing spectral energy distributions
(SEDs) and Lyman continuum (Lyc) and HeI continuum photon emission rates, for
hot O-type and early B-type stars. We consider solar metallicity stars, with
effective temperatures ranging from 25,000 to 55,000 K and surface gravities
(cm s^-2) logg ranging from 3 to 4, covering the full range of spectral types
and luminosity classes for hot stars. We use our updated (WM-basic) code to
construct radiation-driven wind atmosphere models for hot stars. Our models
include the coupled effects of hydrodynamics and non-LTE radiative transfer in
spherically outflowing winds, including the detailed effects of metal line
blocking and line blanketing on the radiative transfer and energy balance. We
incorporate our hot-star models into our population synthesis code (STARS), and
we compute the time-dependent SEDs and resulting Lyc and HeI emission rates for
evolving star clusters. We present results for continuous and impulsive star
formation for a range of assumed stellar initial mass functions.Comment: 23 pages, 7 figures. To appear in the Astrophysical Journal. For grid
of star models see ftp://wise3.tau.ac.il/pub/star
Effect of Macrocycle Size on the Self-Assembly of Methylimidazolium Surfactant with Sulfonatocalix[n]arenes
The effect of macrocycle size on the association of supramolecular amphiphiles composed of 4-sulfonatocalix[n]arene and 1-methyl-3-tetradecylimidazolium (C14mim+) was studied in aqueous solutions at pH 7. When the cavitand contained four sulfonatophenol units (SCX4), spherical nanoparticle (NP) formation was observed. In contrast, both supramolecular micelle (SM) and NP formation could be attained in the presence of NaCl when the larger, more flexible 4-sulfonatocalix[8]arene (SCX8) served as host compound. The SCX8-promoted self-assembly into SM was enthalpically more favorable than NP production but the molar heat capacity changes in the two processes barely differed. Addition of 50 mM NaCl significantly increased the enthalpy of C14mim+−SCX8 NP formation making thereby the self-organization into SM more favorable. The transformation of SM into NP at high temperature was due to the substantial entropic contribution to the driving force of NP formation. The critical micelle concentration and the local polarity in the headgroup domain were considerably lower for SM compared to those of C14mim+Br conventional micelle
Rare earth doped phosphate fibre amplifier at 1.5 μm for LIDAR
The research work reports on the design and fabrication of a compact optical fibre amplifier operating at 1.5 μm. A novel Yb/Er co-doped phosphate glass was developed and the optical fibre preform fabricated by rod-in-tube technique
Characterization of sub-nanosecond pulsed laser amplification with Er:Yb co-doped phosphate glass fibers
We present an experimental characterization of the amplification of sub-nanosecond duration laser pulses at a wavelength of 1538 nm in short custom-made Er:Yb phosphate glass fibers with different core diameters. The fibers vary in their diameter from 100 µm (highly multi-mode) down to 12 µm (single-mode). The peak power, energy per pulse, and spectral shape of the amplified signal are presented. With our input pulses, the measurements show that the large core diameter fibers do not increase the amplification of the 1538 nm signal. We believe this is due to the high re-absorption of the Er3+ ions in the phosphate fiber. The optimal fiber geometry was found to have a core diameter of 20 µm with a length of 14 cm. The maximum peak power is 8.25 kW, corresponding to a net gain of 10.9 dB, with a pulse duration of 0.7 ns and a repetition rate of 40 kHz
Mergers and Mass Accretion Rates in Galaxy Assembly: The Millennium Simulation Compared to Observations of z~2 Galaxies
Recent observations of UV-/optically selected, massive star forming galaxies
at z~2 indicate that the baryonic mass assembly and star formation history is
dominated by continuous rapid accretion of gas and internal secular evolution,
rather than by major mergers. We use the Millennium Simulation to build new
halo merger trees, and extract halo merger fractions and mass accretion rates.
We find that even for halos not undergoing major mergers the mass accretion
rates are plausibly sufficient to account for the high star formation rates
observed in z~2 disks. On the other hand, the fraction of major mergers in the
Millennium Simulation is sufficient to account for the number counts of
submillimeter galaxies (SMGs), in support of observational evidence that these
are major mergers. When following the fate of these two populations in the
Millennium Simulation to z=0, we find that subsequent mergers are not frequent
enough to convert all z~2 turbulent disks into elliptical galaxies at z=0.
Similarly, mergers cannot transform the compact SMGs/red sequence galaxies at
z~2 into observed massive cluster ellipticals at z=0. We argue therefore, that
secular and internal evolution must play an important role in the evolution of
a significant fraction of z~2 UV-/optically and submillimeter selected galaxy
populations.Comment: 5 pages, 4 figures, Accepted for publication in Ap
Effect of pancreatic and/or renal transplantation on diabetic autonomic neuropathy
Thirty-nine Type 1 (insulin-dependent) diabetic patients were studied prospectively after simultaneous pancreas and kidney (n=26) and kidney grafting alone (n=13) by measuring heart rate variation during various manoeuvers and answering a standardized questionnaire every 6 to 12 months post-transplant. While age, duration of diabetes, and serum creatinine (168.1±35.4 vs 132.7±17.7 mgrmol/l) were comparable, haemoglobin A1 levels were significantly lower (6.6±0.2 vs 8.5±0.3%; p<0.01) and the mean observation time longer (35±2 vs 25±3 months; p<0.05) in the pancreas recipients when compared with kidney transplanted patients. Heart rate variation during deep breathing, lying/standing and Valsalva manoeuver were very similar in both groups initially and did not improve during follow-up. However, there was a significant reduction in heart rate in the pancreas recipient group. Autonomic symptoms of the gastrointestinal and thermoregulatory system improved more in the pancreas grafted subjects, while hypoglycaemia unawareness deteriorated in the kidney recipients. This study suggests that long-term normoglycaemia by successful pancreatic grafting is able to halt the progression of autonomic dysfunction
Mitochondrial respiratory capacity is a critical regulator of CD8<sup>+</sup> T cell memory development
CD8+ T cells undergo major metabolic changes upon activation, but how metabolism influences the establishment of long-lived memory T cells after infection remains a key question. We have shown here that CD8+ memory T cells, but not CD8+ T effector (Teff) cells, possessed substantial mitochondrial spare respiratory capacity (SRC). SRC is the extra capacity available in cells to produce energy in response to increased stress or work and as such is associated with cellular survival. We found that interleukin-15 (IL-15), a cytokine critical for CD8+ memory T cells, regulated SRC and oxidative metabolism by promoting mitochondrial biogenesis and expression of carnitine palmitoyl transferase (CPT1a), a metabolic enzyme that controls the rate-limiting step to mitochondrial fatty acid oxidation (FAO). These results show how cytokines control the bioenergetic stability of memory T cells after infection by regulating mitochondrial metabolism
Commitment to glycolysis sustains survival of NO-producing inflammatory dendritic cells
TLR agonists initiate a rapid activation program in dendritic cells (DCs) that requires support from metabolic and bioenergetic resources. We found previously that TLR signaling promotes aerobic glycolysis and a decline in oxidative phosphorylation (OXHPOS) and that glucose restriction prevents activation and leads to premature cell death. However, it remained unclear why the decrease in OXPHOS occurs under these circumstances. Using real-time metabolic flux analysis, in the present study, we show that mitochondrial activity is lost progressively after activation by TLR agonists in inflammatory blood monocyte–derived DCs that express inducible NO synthase. We found that this is because of inhibition of OXPHOS by NO and that the switch to glycolysis is a survival response that serves to maintain ATP levels when OXPHOS is inhibited. Our data identify NO as a profound metabolic regulator in inflammatory monocyte–derived DCs
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