677 research outputs found
Telespectrograph Patent
Telespectrograph for analyzing upper atmosphere by tracking bodies reentering atmosphere at high velocitie
Providing Complete Precision Timing Solution for Hospitals by GPS Time Synchronized with MCS
The time is very important in the life and hasa special significance for hospitals, Where is specially used inoperating rooms, Nurse Call System (NCS) , various medicaltests and many other medical services. Those importantthings are mainly to use Master Clock System (MCS) in thehospitals. In this paper we provided high precision time forhospitals by used Global Positioning System (GPS) timesynchronized with MCS. The time will get synchronizedfrom satellite via GPS according to the Time Zone. GPSreceivers can provide precise time, speed, and coursemeasurements. Westerstrand GPS unit uses a miniature 12-channel GPS will use in the system and its compact size andlow power consumption make it ideal for this application.The system consists of Master clock control unit, GPSreceiver with antenna and related accessories
STEPS-T Program Improves Endovascular Treatment Outcomes of Acute Ischemic Stroke; A 6-Year Study
Background: Early endovascular recanalization of occluded vessels in acute ischemic stroke (AIS) is a major contributor to good clinical outcome. We report the analysis of all AIS patients throughout a 6-year experience following the deployment of a quality initiative aiming at improving care, speed and maintaining quality for AIS treatment.
Methods: Using a prospectively collected endovascular database at a comprehensive stroke center between 2012 and 2017, workflow/outcomes were recorded. There were no exclusion criteria. During the first year, a quality program employing “digital-object” technology, staff education, and workflow improvement was implemented to reduce time-to-treatment. Using electronic recording, workflow times were collected for onset (TO), CT (TCT), door (TD), angiography-suite (TA), groin puncture (TG), DSA (TDSA), and recanalization (TR). Recanalization time (TG-TR) and workflow intervals were compared at Year 1 and 6.
Results: Analysis of 382 patients (aged 71.3 ± 12.9) undergoing mechanical thrombectomy for AIS (206 male and 176 female) was performed. Recanalization time was significantly reduced from 82min in 2012 to 34min by 2017 (IQR 52–117min and 23–49min), a 59% reduction (P \u3c 0.001). Further, consistent year-over-year reductions in setup time (TA-TG) (44% improvement) and TCT to TA times were observed. During the same period, clinical outcome significantly improved year-over-year as measured with the modified Rankin Scale 0–2 (33, 37, 38, 41, 53, and 58%).
Conclusions: Significant improvements were observed following the deployment of a quality initiative enabling iterative evidence-based process improvements, thereby sustaining significant reductions in time-to-treat and improved clinical outcomes for AIS patients
Molecular typing and integron detection of multidrug-resistant Klebsiella pneumoniae clinical isolates recovered from Baquba Teaching Hospital in Iraq
Klebsiella pneumoniae is a gram-negative bacterium that causes severe illnesses and is antibiotic-resistant. This study aimed to determine the antibiotic resistance profile and prevalence of classII and III Iintegrons and ERIC -PCR among clinical isolates of K. pneumoniae. The study was conducted between September 2022 and January 2023. Fifty isolates were obtained from 230 specimens (wounds, burns, blood, fluid, ears,urine and sputum). Macroscopic, microscopic, and biochemical assays were used to identify all K.pneumoniae isolates, which were confirmed with the genetically by 16S rRNA. All isolates were examined for various types of clinically significant antibiotic drugs. The results of resistance to antibiotics indicated resistance to Amoxilline-clavulanc acid(98%), Meropenem (38%), Ceftazidime (96%), Amikacin (48%), Trimethopri-sulfamethoxazole (58.62%) and Levofloxacin (46%).The testing for antibiotic susceptibility of the K.pneumoniaeisolate showed that 24 (48%) of the isolates were multi-drug resistant (MDR). K.pneumoniae β-lactamase producers (ESBL) appeared33(66%). Enterobacterial repetitive intergenic consensus (ERIC) amplification of 16 clinical K. pneumoniae isolates showed 14 (87.5 %) of Each of them revealed at least one amplification band. ERIC-PCR typing found two groups, A and B, with identical antimicrobial resistance patterns within the same group. While IntegronII showed that 1(6.25 %) of K. pneumoniae isolates was integrase gene positive. Class III integrons were seen in all isolates at a rate of 16 (100%).Continuous monitoring and characterization of integrons and their associated gene cassettes could be helpful in controlling the rate of antibiotic resistance by planning to take preventive measures to hinder the spread of resistant strains
Renal and hemodynamic responses to bumetanide in hypertension: Effects of nitrendipine
Renal and hemodynamic responses to bumetanide in hypertension: Effects of nitrendipine. The effects of a calcium antagonist on the response to a loop diuretic were tested in eight hypertensive patients while they received 120mmol · 24hr-1 of dietary Na. Nitrendipine (N; 20 mg) or placebo (P) was administered twice daily for five days and bumetanide (B; 1 mg, i.v.) for the last three days of each period. Cardiac index (CI) was measured during tilt. B alone significantly (P < 0.05; N = 7) reduced CI and increased total peripheral resistance; N prevented these effects of B. Neither drug altered BP consistently. Although three days of B increased plasma renin activity (PRA) during P and N, it increased plasma aldosterone (PAldo) only during P (P, 4.4 ± 1.3 to 7.6 ± 1.0; P < 0.05. N, 5.7 ± 1.3 to 6.0 ± 1.3; pg · liter-1; NS). B increased Na excretion without changing GFR or RPF; this was followed by 18 hours of decreased renal Na excretion. These actions were unchanged by N. N did not change the cumulative excretion of B (P, 268 ± 35 vs. N, 217 ± 21 µg) or the relationship between Na excretion and the log of B excretion. However, Na excretion was increased (P < 0.05) by 40 to 60% in the six hour period following the first two doses of N. Therefore, the cumulative Na balance was more negative during five days of N (P, -47 ± 17 vs. N, -108 ± 24 mmol; P < 0.05). The effect of N and B on Na balance were independent. In conclusion, short-term administration of N: 1) increases CI and reduces TPRI in the post-diuretic state; 2) blunts B-induced increase in PAldo without modifying the rise in PRA; 3) does not change B kinetics or dynamics or the post-diuretic period of renal Na retention; 4) causes negative Na balance which is additive with that produced by B
Enzyme changes during seed storage in groundnut (Arachis hypogaea L.)
A change in enzyme activity in seeds due to ageing is a topic of scientific importance. Vigour is essentially a physiological phenomenon influenced by the reserved metabolites, enzyme activities and growth regulators. The exact cause of loss of seed vigour and viability is still unknown as deterioration of seed is a complex process. In the presence of oxygen, ageing of seed can lead to peroxidative changes in polyunsaturated fatty acids. The free radical -induced non-enzymatic peroxidation, which has the potential to damage membrane, is likely to be a primary cause of deterioration of stored seeds. Certain anabolic enzymes help in maintaining viability while some catabolic enzymes decrease viability. The seed catalase and peroxidase activity seem to be decreased during storage. The results revealed that the peroxidase enzyme activity decreased from 0.236 to 0.444 OD 10 min-1 when storage period increased. A decrease in catalase activity from 0.454 to 0.444 ?g H2O2 mg-1 min-1 followed by a small increase from 0.434 to 0.452 ?g H2O2 mg-1 min-1 was observed during storage. But the activity of lipase enzyme increased from 0.236 to 0.231 meq min-1g-1 of sample when the storage period was increased. The study would help to know the deterioration pattern of stored groundnut seeds
Initial Experience With the Next-Generation Resolute Onyx Zotarolimus-Eluting Stent in Symptomatic Intracranial Atherosclerotic Disease
Background and Purpose: Intracranial atherosclerotic disease (ICAD) is a common cause of stroke worldwide. Although there are different endovascular options for the treatment of symptomatic ICAD (sICAD), it is still controversial. Herein, we aim to study the safety and efficacy of a new generation of drug-eluting balloon-mounted stent (DES); Resolute (R) onyx DES in the treatment of sICAD.
Methods:A prospectively maintained neuroendovascular procedures database in a high-volume comprehensive stroke center was reviewed from October 2019 through January 2020. Patients were included if they had sICAD (≥70% stenosis), failed medical management, and underwent intracranial stenting with R-onyx DES. Technical success was defined as the ability to deploy the device at the desired location and achievement of
Results: A total of 18 consecutive patients (mean age, 66.6 years; 44.4% were females and 94.4% were Hispanic) were eligible for the analysis. Indication for treatment was recurrent strokes in 13 and recurrent transient ischemic attack (TIA) in 5. A total of 22 symptomatic lesions with a mean baseline stenosis percent (84.9 ± 9.6) were treated using 23 R-onyx DES in 19 procedures. All procedures were done under general anesthesia with 100% technical success, and no reported periprocedural strokes or death. Among 13 patients who had clinical follow-up, 1 (7.7%) patient had TIA. There were no reported ischemic or hemorrhagic strokes. Angiographic follow-up for 9 (50%) patients showed no in-stent restenosis.
Conclusion: The use of R-onyx DES in the treatment of sICAD is safe with high technical success rates. Large prospective multicenter trials with long-term follow-up are warranted
On an accidental stranding, rescue and return of hump-back dolphins at Tuticorin harbour area
Reports on the accidental stranding and
inadvertant landings of marine mammals, mostly
dolphins, porpoises and dugongs by different
gears such as drift gillnets, trawlnets, purse
seines etc., along the Indian coasts are well
documented by different workers in recent days.
Consequent to the sustained efforts by different
International Agencies, awareness is created
among the public on the conservation of the
endangered marine mammals and on certain
occasions the people themselves get involved in
the act of saving the lives of marine mammals
Culture of the sea bass Lates calcarifer
Studies on the growth of Lates calcarifer cultured in coastal
ponds and net cages in the three different places at Tuticorin
showed an increase of 16.2-23.2 mm/ 18.6- 53.2 g/ month at
Karapad, 21.1-29.8mm/19.3- 36.3 g / month at Veppalodai in
coastal ponds and 21.6-32.4 mm/ 31.4-55.0 g / month in a net
cage in the Tuticorin Bay. The growth in Karapad pond, where
supplementary feed was provided was better than in Veppalodai
pond. The highest growth rate was obtained in net cage culture
at Tuticorin Bay. Length-frequency analysis of samples from
commercial catch reveal a faster growth in the wild than in the
culture systems. The better growth in the brackishwater culture
and in the wild is attributed to the lower salinity and better
live feed availability in brackishwater. In the pond system, the
growth can be improved by maintaining proper water exchange
so as to maintain the salinity equivalent to open sea/bay/
brackishwaters and by providing supplementary feed
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