67 research outputs found
Crystal structure of 2-azido-1,3-bis(2,6-diiso- propylphenyl)-1,3,2-diazaphospholidine
- Publication venue
- 'International Union of Crystallography (IUCr)'
- Publication date
- 31/05/2017
- Field of study
Published VersionThe title compound, C26H38N5P, was synthesized by reacting 2-chloro-1,3-
bis(2,6-diisopropylphenyl)-1,3,2-diazaphospholidine with sodium azide and a
catalytic amount of lithium chloride in tetrahydrofuran. The title compound is
the first structurally characterized 2-azido-1,3,2-diazaphospholidine and exhibits
a P atom in a trigonal pyramidal geometry. The azide P—N bond length of
1.8547 (16) A ̊ is significantly longer than the P—N separations for the chelating
diamine [P—N = 1.6680 (15) and 1.6684 (14) A ̊ ]. The sterically hindered 2,6-
diisopropylphenyl groups twist away from the central heterocycle, with dihedral
angles between the central heteocyclic ring and benzene rings of 76.17 (10) and
79.74 (9) . In the crystal, a weak C—H...N link to the terminal N atom of the
azide group leads to [100] chains
1-(2,4,6-Triisopropylphenyl)ethanone
- Author
- Publication venue
- International Union of Crystallography
- Publication date
- 01/10/2011
- Field of study
The title compound, C17H26O, is a di-ortho-alkyl substituted phenyl ethanone that exhibits a significant twisting of the ketone fragment relative to the aromatic ring [O—C—C—C torsion angle = 89.32 (17)°] due to steric pressure from the ortho-isopropyl groups. One ortho- and the para-isopropyl group exhibit orientational disorder with a refined site occupancy factor of 0.562 (3):0.438 (3)
Fluorescent amplified fragment length polymorphism analysis of Bacillus anthracis, Bacillus cereus, and Bacillus thuringiensis isolates
- Author
- Publication venue
- 'American Society for Microbiology'
- Publication date
- 01/01/2004
- Field of study
DNA from over 300 Bacillus thuringiensis, Bacillus cereus, and Bacillus anthracis isolates was analyzed by fluorescent amplified fragment length polymorphism (AFLP). B. thuringiensis and B. cereus isolates were from diverse sources and locations, including soil, clinical isolates and food products causing diarrheal and emetic outbreaks, and type strains from the American Type Culture Collection, and over 200 B. thuringiensis isolates representing 36 serovars or subspecies were from the U.S. Department of Agriculture collection. Twenty-four diverse B. anthracis isolates were also included. Phylogenetic analysis of AFLP data revealed extensive diversity within B. thuringiensis and B. cereus compared to the monomorphic nature of B. anthracis. All of the B. anthracis strains were more closely related to each other than to any other Bacillus isolate, while B. cereus and B. thuringiensis strains populated the entire tree. Ten distinct branches were defined, with many branches containing both B. cereus and B. thuringiensis isolates. A single branch contained all the B. anthracis isolates plus an unusual B. thuringiensis isolate that is pathogenic in mice. In contrast, B. thuringiensis subsp. kurstaki (ATCC 33679) and other isolates used to prepare insecticides mapped distal to the B. anthracis isolates. The interspersion of B. cereus and B. thuringiensis isolates within the phylogenetic tree suggests that phenotypic traits used to distinguish between these two species do not reflect the genomic content of the different isolates and that horizontal gene transfer plays an important role in establishing the phenotype of each of these microbes. B. thuringiensis isolates of a particular subspecies tended to cluster together
Effects of antiplatelet therapy on stroke risk by brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases: subgroup analyses of the RESTART randomised, open-label trial
- Author
- Abano Nenette
- Abbdul-saheb Mudhar
- Adedoyin Temi
- Adell Victoria
- Adesina Tolu
- Adie Katja
- Adil-Smith Jennifer
- Ahmad Nasar
- Ahmed Ashraf
- Ahmed Iman
- Al-Mayhani Talal
- Al-Shahi Salman Rustam
- Al-Shahi Salman Rustam
- Alam Mohammad Irfan
- Albazzaz Mo
- Ali Ali
- Alipio Francis
- Allen Christopher
- Allison Joanna
- Amey Isobel
- Amis Elaine
- Amlani Sageet
- Amoils Shannon
- Amor Kelly
- Anderson Rosemary
- Andole Sreeman
- Anjum Talat
- Ankolekar Sandeep
- Annamalai Arunkumar
- Anthony Alpha
- Anversha Ajmal
- Anwar Ijaz
- Anwar Sajjad
- Appleton Jason
- Argandona Lucia
- Armitage Jane
- Ashton Amy
- Atkinson Natalie
- Auld Grace
- Avis Joanne
- Aweid Basaam
- Ayres Georgina
- Azhar Khalid
- Bagnall Caroline
- Baig Farrukh
- Baigent Colin
- Bailey Duncan
- Baird Yolanda
- Bakawala Rehana
- Baker John
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- Banaras Azra
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- Bhakri Harbens
- Bhalla Ajay
- Bharaj Kiranjit
- Bhargava Maneesh
- Bhaskaran Biju
- Bhatnagar Priya
- Bhatnagar Priya
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- Birns Jonathan
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- du Plessis Johann C
- du Plessis Johannes
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- Hayhoe Helen
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- Joshi Yogish
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- Jupp Becky
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- Kalathil Latheef
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- Langhorne Peter
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- Lerpiniere Christine
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- Loganathan Thayalini
- Longland Barbara
- Lopez Paula
- Lovelock Caroline
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- Lucas Suzanne
- Luder Robert
- Lyjko Sue
- Maanoosi Mehran
- Maatouk Ahmad
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- Manoj Aravind
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- Minks David P.
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- Mitra Dipayan
- Mitra Dipayan
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- Ramshaw Alex
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- Rashmi Sindhu
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- Reddan Julie
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- Richards Emma
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- Rodriguez Aryelly
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- Sakka Eleni
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- Salek-Haddadi Afraim
- Salih Isam
- Sally Moore
- Sandercock Peter A G
- Sangombe Mirriam
- Sangster Graeme
- Sanyal Ranjan
- Sarah Procter
- Sarah Procter
- Sattar Naweed
- Sattar Saira
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- Saulat Afaq
- Schofield Christine
- Schulz Ursula
- Schumacher Natasha
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- Seagrave Samantha
- Sekaran Lakshmanan
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- Shahmehri Shahrzad
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- Sharpe Simon
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- Shaw Louise
- Sheikh Saima
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- Shukla Avani
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- Siddiq Muhammad
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- Sprigg Nikola
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- Stafford Samantha
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- Subramonian Santhosh
- Sudlow Cathie
- Sudlow Cathie L M
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- Thornthwaite Sarah
- Thorpe Kevin
- Tilley Victoria
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- Vickers Carinna
- Walford Jamie
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- Walker Marion
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- Walker Susannah
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- Wallace Rebecca
- Wallace Rebecca
- Walstow Deborah
- Walter Deborah
- Walters Ashleigh
- Wani Mushtaq
- Ward Deborah
- Wardlaw Joanna M
- Watchurst Caroline
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- Waterfield Kelly
- Watson Fran
- Waugh Dean
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- Webber Adam
- Webster Timothy
- Weinling Marie
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- Weir Pauline
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- Werring David
- Werring David J
- Whitcher Alison
- White James
- White Julie
- White Philip M
- White Susan
- Whiteley William
- Whiteley William N
- Whiteman Jessica
- Whiteman Jessica
- Whiting Robert
- Whittamore Katherine
- Wiggam Ivan
- Wilding Peter
- Wilkes Gwendoline
- Wilkinson Mark
- Willberry Angela
- Williams Carol
- Williams Rebecca
- Williams-Yesson Barbara
- Willmot Mark
- Wilson David
- Wilson Duncan
- Wilson Jenny
- Wilson Lisa
- Wilson Sarah
- Wiltshire Alison
- Wood Diane
- Wood Edith
- Wood Lisa
- Woodward Stephen
- Wright Fiona
- Wroath Belinda
- Wynter Inez
- Yadava Rajendra
- Yip Brigitte
- Young Andrew
- Zachariah George
- Zahoor Tajammal
- Zoe Mellor
- Publication venue
- 'Elsevier BV'
- Publication date
- 22/05/2019
- Field of study
Background
Findings from the RESTART trial suggest that starting antiplatelet therapy might reduce the risk of recurrent symptomatic intracerebral haemorrhage compared with avoiding antiplatelet therapy. Brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases (such as cerebral microbleeds) are associated with greater risks of recurrent intracerebral haemorrhage. We did subgroup analyses of the RESTART trial to explore whether these brain imaging features modify the effects of antiplatelet therapy
Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016
- Author
- Abajobir Amanuel Alemu
- Abate Kalkidan Hassen
- Abbafati Cristiana
- Abbas Kaja M.
- Abd-Allah Foad
- Abdulle Abdishakur M.
- Abebo Teshome Abuka
- Abera Semaw Ferede
- Aboyans Victor
- Abu-Raddad Laith J.
- Ackerman Ilana N.
- Adamu Abdu Abdullahi
- Adetokunboh Olatunji
- Afarideh Mohsen
- Afshin Ashkan
- Agarwal Sanjay Kumar
- Aggarwal Rakesh
- Agrawal Anurag
- Agrawal Sutapa
- Ahmad Kiadaliri Aliasghar
- Ahmadieh Hamid
- Ahmed Muktar Beshir
- Aichour Amani Nidhal
- Aichour Ibtihel
- Aichour Miloud Taki Eddine
- Aiyar Sneha
- Akinyemi Rufus Olusola
- Akseer Nadia
- Al Lami Faris Hasan
- Al-Aly Ziyad
- Al-Maskari Fatma
- Al-Raddadi Rajaa
- Alahdab Fares
- Alam Khurshid
- Alam Noore
- Alam Tahiya
- Alasfoor Deena
- Alene Kefyalew Addis
- Ali Raghib
- Alizadeh-Navaei Reza
- Alkerwi Ala'a
- Alla François
- Allebeck Peter
- Allen Christine
- Alsharif Ubai
- Alsowaidi Shirina
- Altirkawi Khalid A.
- Amare Azmeraw T.
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- Shaheen Amira
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- Shariful Islam Sheikh Mohammed
- Sharma Jayendra
- Sharma Rajesh
- She Jun
- Shi Peilin
- Shields Chloe
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- Steiner Timothy J.
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- Stovner Lars Jacob
- Strub Bryan
- Subart Michelle
- Sufiyan Muawiyyah Babale
- Suliankatchi Abdulkader Rizwan
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- Sur Patrick J.
- Swaminathan Soumya
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- Tabarés-Seisdedos Rafael
- Taffere Getachew Redae
- Takala Jukka S.
- Tandon Nikhil
- Tavakkoli Mohammad
- Taveira Nuno
- Taylor Hugh R.
- Tehrani-Banihashemi Arash
- Tekelab Tesfalidet
- Temam Shifa Girma
- Terkawi Abdullah Sulieman
- Tesfaye Dawit Jember
- Tesssema Belay
- Thamsuwan Ornwipa
- Thomas Katie E.
- Thrift Amanda G.
- Tiruye Tenaw Yimer
- Tobe-Gai Ruoyan
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- Tonelli Marcello
- Topor-Madry Roman
- Tortajada Miguel
- Touvier Mathilde
- Tran Bach Xuan
- Tripathi Suryakant
- Troeger Christopher
- Truelsen Thomas
- Tsoi Derrick
- Tuem Kald Beshir
- Tuzcu Emin Murat
- Tyrovolas Stefanos
- Ukwaja Kingsley N.
- Undurraga Eduardo A.
- Uneke Chigozie Jesse
- Updike Rachel
- Uthman Olalekan A.
- Uzochukwu Benjamin S. Chudi
- Van Boven Job F.M.
- Varughese Santosh
- Vasankari Tommi
- Venkatesh
- Venketasubramanian Narayanaswamy
- Vidavalur Ramesh
- Violante Francesco S.
- Vladimirov Sergey K.
- Vlassov Vasiliy Victorovich
- Vollset Stein Emil
- Vos Theo
- Wadilo Fiseha
- Wakayo Tolassa
- Wang Yuan-Pang
- Weaver Marcia
- Weichenthal Scott
- Weiderpass Elisabete
- Weintraub Robert G.
- Werdecker Andrea
- Westerman Ronny
- Whiteford Harvey A.
- Wijeratne Tissa
- Wiysonge Charles Shey
- Wolfe Charles D.A.
- Woodbrook Rachel
- Woolf Anthony D.
- Workicho Abdulhalik
- Wulf Hanson Sarah
- Xavier Denis
- Xu Gelin
- Yadgir Simon
- Yaghoubi Mohsen
- Yakob Bereket
- Yan Lijing L.
- Yano Yuichiro
- Ye Pengpeng
- Yimam Hassen Hamid
- Yip Paul
- Yonemoto Naohiro
- Yoon Seok-Jun
- Yotebieng Marcel
- Younis Mustafa Z.
- Zaidi Zoubida
- Zaki Maysaa El Sayed
- Zegeye Elias Asfaw
- Zenebe Zerihun Menlkalew
- Zhang Xueying
- Zhou Maigeng
- Zipkin Ben
- Zodpey Sanjay
- Zuhlke Liesl Joanna
- Ärnlöv Johan
- Publication venue
- Publication date
- 01/01/2017
- Field of study
As mortality rates decline, life expectancy increases, and populations age, non-fatal outcomes of diseases and injuries are becoming a larger component of the global burden of disease. The Global Burden of Diseases, Injuries, and Risk Factors Study 2016 (GBD 2016) provides a comprehensive assessment of prevalence, incidence, and years lived with disability (YLDs) for 328 causes in 195 countries and territories from 1990 to 2016
The Science Performance of JWST as Characterized in Commissioning
- Author
- Abell Jim
- Abney Faith
- Abul-Huda Yasin
- Acton D. Scott
- Adams Evan
- Adler David
- Aguilar Jonathan
- Ahmed Nasif
- Alarcon Rafael Ramos
- Albert Loïc
- Alberts Stacey
- Aldridge David
- Allen Marsha
- Altenburg Martin
- Alvarez Jose Lorenzo
- Andersen Greg
- Anderson Harry
- Anderson Sara
- Argyriou Ioannis
- Armstrong Amber
- Arribas Santiago
- Artigau Etienne
- Arvai Amanda
- Atkinson Charles
- Bacon Gregory
- Bair Thomas
- Banks Kimberly
- Barrientes Jaclyn
- Barringer Bruce
- Bartosik Peter
- Bast William
- Baudoz Pierre
- Beatty Thomas
- Bechtold Katie
- Beck Tracy
- Bergeron Eddie
- Bergkoetter Matthew
- Bhatawdekar Rachana
- Birkmann Stephan
- Blazek Ronald
- Blome Claire
- Boccaletti Anthony
- Boeker Torsten
- Boia John
- Bonaventura Nina
- Bond Nicholas
- Bosley Kari
- Boucarut Ray
- Bourque Matthew
- Bouwman Jeroen
- Bower Gary
- Bowers Charles
- Boyer Martha
- Bradley Larry
- Brady Greg
- Braun Hannah
- Breda David
- Bresnahan Pamela
- Bright Stacey
- Britt Christopher
- Bromenschenkel Asa
- Brooks Brian
- Brooks Keira
- Brown Bob
- Brown Matthew
- Brown Patricia
- Bunker Andy
- Burger Matthew
- Bushouse Howard
- Cale Steven
- Cameron Alex
- Cameron Peter
- Canipe Alicia
- Caplinger James
- Caputo Francis
- Cara Mihai
- Carey Larkin
- Carniani Stefano
- Carrasquilla Maria
- Carruthers Margaret
- Case Michael
- Catherine Riggs
- Chance Don
- Chapman George
- Charlot Stéphane
- Charlow Brian
- Chayer Pierre
- Chen Bin
- Cherinka Brian
- Chichester Sarah
- Chilton Zack
- Chonis Taylor
- Clampin Mark
- Clark Charles
- Clark Kerry
- Coe Dan
- Coleman Benee
- Colon Knicole
- Comber Brian
- Comeau Tom
- Connolly Dennis
- Cooper James
- Cooper Rachel
- Coppock Eric
- Correnti Matteo
- Cossou Christophe
- Coulais Alain
- Coyle Laura
- Cracraft Misty
- Curti Mirko
- Cuturic Steven
- Davis Katherine
- Davis Michael
- de Oliveira Catarina Alves
- Dean Bruce
- Del Pino Bruno Rodriguez
- DeLisa Amy
- deMeester Wim
- Dencheva Nadezhda
- Dencheva Nadia
- DePasquale Joseph
- Deschenes Jeremy
- Detre Örs Hunor
- Diaz Rosa
- Dicken Dan
- DiFelice Audrey
- Dillman Matthew
- Dixon William
- Doggett Jesse
- Donaldson Tom
- Douglas Rob
- Doyon René
- DuPrie Kimberly
- Dupuis Jean
- Durning John
- Easmin Nilufar
- Eck Weston
- Edeani Chinwe
- Egami Eiichi
- Ehrenwinkler Ralf
- Eisenhamer Jonathan
- Eisenhower Michael
- Elie Michelle
- Elliott James
- Elliott Kyle
- Ellis Tracy
- Engesser Michael
- Espinoza Nestor
- Etienne Odessa
- Etxaluze Mireya
- Falini Patrick
- Feeney Matthew
- Feinberg Lee
- Ferruit Pierre
- Ferry Malcolm
- Filippazzo Joseph
- Fincham Brian
- Fix Mees
- Flagey Nicolas
- Florian Michael
- Flynn Jim
- Fontanella Erin
- Ford Terrance
- Forshay Peter
- Fox Ori
- Franz David
- Friedman Scott
- Fu Henry
- Fullerton Alexander
- Galkin Sergey
- Galyer Anthony
- Gardner Jonathan
- Gardner Lisa
- Garland Dennis
- Garrett Bruce
- Gasman Danny
- Gaspar Andras
- Gaudreau Daniel
- Gauthier Peter
- Geers Vincent
- Geithner Paul
- Gennaro Mario
- Giardino Giovanna
- Girard Julien
- Giuliano Mark
- Glasse Alistair
- Glassmire Kirk
- Glauser Adrian
- Glazer Stuart
- Godfrey John
- Golimowski David
- Gollnitz David
- Gong Fan
- Gonzaga Shireen
- Gordon Karl
- Gordon Michael
- Goudfrooij Paul
- Greene Thomas
- Greenhouse Matthew
- Grimaldi Stefano
- Groebner Andrew
- Grundy Timothy
- Guillard Pierre
- Gutman Irvin
- Ha Kong Q.
- Haderlein Peter
- Hagedorn Andria
- Hainline Kevin
- Haley Craig
- Hami Maryam
- Hamilton Forrest
- Hammel Heidi
- Hansen Carl
- Harkins Tom
- Harr Michael
- Hart Jessica
- Hart Quyen
- Hartig George
- Hashimoto Ryan
- Haskins Sujee
- Hathaway William
- Havey Keith
- Hayden Brian
- Hecht Karen
- Heller-Boyer Chris
- Henriques Caroline
- Henry Alaina
- Hermann Karl
- Hernandez Scarlin
- Hesman Brigette
- Hicks Brian
- Hilbert Bryan
- Hines Dean
- Hoffman Melissa
- Holfeltz Sherie
- Holler Bryan J.
- Hoppa Jennifer
- Hott Kyle
- Howard Joseph
- Howard Rick
- Hunter Alexander
- Hunter David
- Hurst Brendan
- Husemann Bernd
- Hustak Leah
- Ignat Luminita Ilinca
- Illingworth Garth
- Irish Sandra
- Jackson Wallace
- Jahromi Amir
- Jakobsen Peter
- James Bryan
- James LeAndrea
- Januszewski William
- Jenkins Ann
- Jirdeh Hussein
- Johnson Phillip
- Johnson Timothy
- Jones Danny
- Jones Olivia
- Jones Ron
- Jones Vicki
- Jordan Ian
- Jordan Margaret
- Jurczyk Sarah
- Jurling Alden
- Kaleida Catherine
- Kalmanson Phillip
- Kammerer Jens
- Kang Huijo
- Kao Shaw-Hong
- Karakla Diane
- Kavanagh Patrick
- Kelly Doug
- Kendrew Sarah
- Kennedy Herbert
- Kenny Deborah
- Keski-kuha Ritva
- Keyes Charles
- Kidwell Richard
- Kimble Randy
- Kinzel Wayne
- Kirk Jeff
- Kirkpatrick Mark
- Kirshenblat Danielle
- Klaassen Pamela
- Knapp Bryan
- Knight J. Scott
- Knollenberg Perry
- Koehler Robert
- Koekemoer Anton
- Kovacs Aiden
- Kulp Trey
- Kumari Nimisha
- Kyprianou Mark
- La Massa Stephanie
- Labador Aurora
- Lagage Pierre-Olivier
- Lajoie Charles-Phillipe
- Lallo Matt
- Lallo Matthew
- Lam May
- Lamb Tracy
- Lambros Scott
- Lampenfield Richard
- Langston James
- Larson Kirsten
- Law David
- Lawrence Jon
- Lee David
- Leisenring Jarron
- Lepo Kelly
- Leveille Michael
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- Wu Rai
- Wymer Kristen
- Yates Kayla
- Yeager Christopher
- Yeates Jared
- Yerger Ethan
- Yoon Jinmi
- Young Alice
- Yu Susan
- Zak Dean
- Zeidler Peter
- Zhou Julia
- Zielinski Thomas
- Zincke Cristian
- Zonak Stephanie
- Publication venue
- 'IOP Publishing'
- Publication date
- 10/04/2023
- Field of study
This paper characterizes the actual science performance of the James Webb
Space Telescope (JWST), as determined from the six month commissioning period.
We summarize the performance of the spacecraft, telescope, science instruments,
and ground system, with an emphasis on differences from pre-launch
expectations. Commissioning has made clear that JWST is fully capable of
achieving the discoveries for which it was built. Moreover, almost across the
board, the science performance of JWST is better than expected; in most cases,
JWST will go deeper faster than expected. The telescope and instrument suite
have demonstrated the sensitivity, stability, image quality, and spectral range
that are necessary to transform our understanding of the cosmos through
observations spanning from near-earth asteroids to the most distant galaxies.Comment: 5th version as accepted to PASP; 31 pages, 18 figures;
https://iopscience.iop.org/article/10.1088/1538-3873/acb29
Global, regional, and national under-5 mortality, adult mortality, age-specific mortality, and life expectancy, 1970–2016: a systematic analysis for the Global Burden of Disease Study 2016
- Author
- Abajobir Amanuel Alemu
- Abate Kalkidan Hassen
- Abbafati Cristiana
- Abbas Kaja M.
- Abd-Allah Foad
- Abera Semaw Ferede
- Abraha Haftom Niguse
- Abu-Raddad Laith J.
- Abu-Rmeileh Niveen M.E.
- Adedeji Isaac Akinkunmi
- Adedoyin Rufus Adesoji
- Adetifa Ifedayo Morayo O.
- Adetokunboh Olatunji
- Afshin Ashkan
- Aggarwal Rakesh
- Agrawal Anurag
- Agrawal Sutapa
- Ahmad Kiadaliri Aliasghar
- Ahmed Muktar Beshir
- Aichour Amani Nidhal
- Aichour Ibthiel
- Aichour Miloud Taki Eddine
- Aiyar Sneha
- Akanda Ali Shafqat
- Akinyemiju Tomi F.
- Akseer Nadia
- Al Lami Faris Hasan
- Al-Aly Ziyad
- Al-Eyadhy Ayman
- Al-Raddadi Rajaa
- Alabed Samer
- Alahdab Fares
- Alam Khurshid
- Alam Noore
- Alasfoor Deena
- Aldridge Robert William
- Alene Kefyalew Addis
- Alhabib Samia
- Ali Raghib
- Alizadeh-Navaei Reza
- Aljunid Syed M.
- Alkaabi Juma M.
- Alkerwi Ala'a
- Alla François
- Allam Shalini D.
- Allebeck Peter
- Alsharif Ubai
- Altirkawi Khalid A.
- Alvis-Guzman Nelson
- Amare Azmeraw T.
- Ameh Emmanuel A.
- Amini Erfan
- Ammar Walid
- Amoako Yaw Ampem
- Anber Nahla
- Andrei Catalina Liliana
- Androudi Sofia
- Ansari Hossein
- Ansha Mustafa Geleto
- Antonio Carl Abelardo T.
- Anwari Palwasha
- Arora Megha
- Artaman Al
- Aryal Krishna Kumar
- Asayesh Hamid
- Asgedom Solomon Weldegebreal
- Asghar Rana Jawad
- Assadi Reza
- Atey Tesfay Mehari
- Atre Sachin R.
- Avila-Burgos Leticia
- Avokpaho Euripide Frinel G. Arthur
- Awasthi Ashish
- Ayala Quintanilla Beatriz Paulina
- Babalola Tesleem Kayode
- Bacha Umar
- Badawi Alaa
- Balakrishnan Kalpana
- Balalla Shivanthi
- Barac Aleksandra
- Barber Ryan M.
- Barboza Miguel A.
- Barker-Collo Suzanne L.
- Barquera Simon
- Barregard Lars
- Barrero Lope H.
- Baune Bernhard T.
- Bazargan-Hejazi Shahrzad
- Bedi Neeraj
- Beghi Ettore
- Bekele Bayu Begashaw
- Bell Michelle L.
- Bello Aminu K.
- Bennett Derrick A.
- Bennett James R.
- Bensenor Isabela M.
- Benson Jennifer
- Berhane Adugnaw
- Berhe Derbew Fikadu
- Bernabé Eduardo
- Beuran Mircea
- Beyene Addisu Shunu
- Bhala Neeraj
- Bhansali Anil
- Bhaumik Soumyadeep
- Bhutta Zulfiqar A.
- Bikbov Boris
- Birungi Charles
- Biryukov Stan
- Bisanzio Donal
- Bizuayehu Habtamu Mellie
- Bjerregaard Peter
- Blosser Christopher D.
- Boneya Dube Jara
- Boufous Soufiane
- Bourne Rupert R.A.
- Brazinova Alexandra
- Breitborde Nicholas J.K.
- Brenner Hermann
- Brugha Traolach S.
- Bukhman Gene
- Bulto Lemma Negesa Bulto
- Bumgarner Blair Randal
- Burch Michael
- Butt Zahid A.
- Bärnighausen Till
- Béjot Yannick
- Cahill Leah E.
- Cahuana-Hurtado Lucero
- Campos-Nonato Ismael Ricardo
- Car Josip
- Car Mate
- Carpenter David O.
- Carrero Juan Jesus
- Carter Austin
- Castañeda-Orjuela Carlos A.
- Castillo Rivas Jacqueline
- Castro Franz F.
- Castro Ruben Estanislao
- Catalá-López Ferrán
- Chen Honglei
- Chiang Peggy Pei-Chia
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- Chisumpa Vesper Hichilombwe
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- Christensen Hanne
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- Ciobanu Liliana G.
- Cirillo Massimo
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- Ding Eric L.
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- Do Huyen Phuc
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- Donnelly Christl Ann
- Dos Santos Kadine Priscila Bender
- Douwes-Schultz Dirk
- Driscoll Tim R.
- Duan Leilei
- Dubey Manisha
- Duncan Bruce Bartholow
- Dwivedi Laxmi Kant
- Ebrahimi Hedyeh
- El Bcheraoui Charbel
- El Sayed Zaki Maysaa
- Ellingsen Christian Lycke
- Enayati Ahmadali
- Endries Aman Yesuf
- Ermakov Sergey Petrovich
- Eshetie Setegn
- Eshrati Babak
- Eskandarieh Sharareh
- Esteghamati Alireza
- Estep Kara
- Fanuel Fanuel Belayneh Bekele
- Faro André
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- Fereshtehnejad Seyed-Mohammad
- Fernandes Jefferson G.
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- Friedman Joseph
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- Gebregergs Gebremedhin Berhe
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- Gemechu Bikila Lencha
- Gemechu Kasiye Shiferaw
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- Gill Paramjit Singh
- Gillum Richard F.
- Giref Ababi Zergaw
- Girma Bedilu Weji
- Giussani Giorgia
- Goenka Shifalika
- Gomez Beatriz
- Gona Philimon N.
- Gopalani Sameer Vali
- Goulart Alessandra Carvalho
- Graetz Nicholas
- Gugnani Harish Chander
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- Haagsma Juanita A.
- Hafezi-Nejad Nima
- Haghparast Bidgoli Hassan
- Hakuzimana Alex
- Halasa Yara A.
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- Hambisa Mitiku Teshome
- Hamidi Samer
- Hammami Mouhanad
- Hancock Jamie
- Handal Alexis J.
- Hankey Graeme J.
- Hao Yuantao
- Harb Hilda L.
- Hareri Habtamu Abera
- Harikrishnan Sivadasanpillai
- Haro Josep Maria
- Hassanvand Mohammad Sadegh
- Havmoeller Rasmus
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- He Fei
- Heredia-Pi Ileana Beatriz
- Herteliu Claudiu
- Hilawe Esayas Haregot
- Hoek Hans W.
- Horita Nobuyuki
- Hosgood H. Dean
- Hostiuc Sorin
- Hotez Peter J.
- Hoy Damian G.
- Hsairi Mohamed
- Htet Aung Soe
- Hu Guoqing
- Huang Hsiang
- Huang John J.
- Iburg Kim Moesgaard
- Igumbor Ehimario Uche
- Ileanu Bogdan Vasile
- Inoue Manami
- Irenso Asnake Ararsa
- Irvine Caleb M.S.
- Islam Nazrul
- Islam Sheikh Mohammed Shariful
- Jacobsen Kathryn H.
- Jaenisch Thomas
- Jahanmehr Nader
- Jakovljevic Mihajlo B.
- Javanbakht Mehdi
- Jayatilleke Achala Upendra
- Jeemon Panniyammakal
- Jensen Paul N.
- Jha Vivekanand
- Jin Ye
- John Denny
- John Oommen
- Johnson Sarah Charlotte
- Jonas Jost B.
- Jürisson Mikk
- Kabir Zubair
- Kadel Rajendra
- Kahsay Amaha
- Kalkonde Yogeshwar
- Kamal Ritul
- Kan Haidong
- Karch André
- Karema Corine Kakizi
- Karimi Seyed M.
- Karthikeyan Ganesan
- Kasaeian Amir
- Kassaw Nigussie Assefa
- Kassebaum Nicholas J.
- Kastor Anshul
- Katikireddi Srinivasa Vittal
- Kaul Anil
- Kawakami Norito
- Kazanjan Konstantin
- Keiyoro Peter Njenga
- Kelbore Sefonias Getachew
- Kemp Andrew Haddon
- Kengne Andre Pascal
- Keren Andre
- Kereselidze Maia
- Kesavachandran Chandrasekharan Nair
- Ketema Ezra Belay
- Khader Yousef Saleh
- Khalil Ibrahim A.
- Khan Ejaz Ahmad
- Khan Gulfaraz
- Khang Young-Ho
- Khera Sahil
- Khoja Abdullah Tawfih Abdullah
- Khosravi Mohammad Hossein
- Kibret Getiye Dejenu
- Kieling Christian
- Kim Cho-Il
- Kim Daniel
- Kim Pauline
- Kim Sungroul
- Kim Yun Jin
- Kimokoti Ruth W.
- Kinfu Yohannes
- Kishawi Sami
- Kissimova-Skarbek Katarzyna A.
- Kissoon Niranjan
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- Knudsen Ann Kristin
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- Kopec Jacek A.
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- Krohn Kristopher J.
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- Kumar G. Anil
- Kumar Pushpendra
- Kumsa Fekede Asefa
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- Lachat Carl
- Lagat Abraham K.
- Lager Anton Carl Jonas
- Lal Dharmesh Kumar
- Lalloo Ratilal
- Lambert Nkurunziza
- Lan Qing
- Lansingh Van C.
- Larson Heidi J.
- Larsson Anders
- Laryea Dennis Odai
- Lavados Pablo M.
- Laxmaiah Avula
- Lee Paul H.
- Leigh James
- Leung Janni
- Leung Ricky
- Levi Miriam
- Li Yongmei
- Liao Yu
- Liben Misgan Legesse
- Lim Stephen S.
- Linn Shai
- Lipshultz Steven E.
- Liu Shiwei
- Lodha Rakesh
- Logroscino Giancarlo
- Lopez Alan D.
- Lorch Scott A.
- Lorkowski Stefan
- Lotufo Paulo A.
- Lozano Rafael
- Lunevicius Raimundas
- Lyons Ronan A.
- Ma Stefan
- Macarayan Erlyn Rachelle King
- Machado Isis Eloah
- Mackay Mark T.
- Magdy Abd El Razek Mohammed
- Magis-Rodriguez Carlos
- Mahdavi Mahdi
- Mahesh
- Majdan Marek
- Majdzadeh Reza
- Majeed Azeem
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- Malhotra Rajesh
- Malta Deborah Carvalho
- Mantovani Lorenzo G.
- Manyazewal Tsegahun
- Mapoma Chabila C.
- Marczak Laurie B.
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- Martin Elena Alvarez
- Martinez-Raga Jose
- Martins-Melo Francisco Rogerlândio
- Massano João
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- McAlinden Colm
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- Meier Toni
- Mekonnen Tefera Chane
- Meles Kidanu Gebremariam
- Memiah Peter
- Memish Ziad A.
- Mendoza Walter
- Mengesha Melkamu Merid
- Mengistie Mubarek Abera
- Mengistu Desalegn Tadese
- Menon Geetha R.
- Menota Bereket Gebremichael
- Mensah George A.
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- Meretoja Tuomo J.
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- Micha Renata
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- Miller Ted R.
- Mills Edward J.
- Minnig Shawn
- Mirarefin Mojde
- Mirrakhimov Erkin M.
- Misganaw Awoke
- Mishra Shiva Raj
- Mohammad Karzan Abdulmuhsin
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- Mohammed Kedir Endris
- Mohammed Shafiu
- Mohan Murali B.V.
- Mohanty Sanjay K.
- Mokdad Ali H.
- Molla Assaye Ashagre
- Mollenkopf Sarah K.
- Molokhia Mariam
- Monasta Lorenzo
- Montañez Hernandez Julio Cesar
- Montico Marcella
- Mooney Meghan D.
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- Moraga Paula
- Morawska Lidia
- Moreno Velasquez Ilais
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- Murthy Gudlavalleti Venkata Satyanarayana
- Murthy Srinivas
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- Nagata Chie
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- Nangia Vinay
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- Natarajan Gopalakrishnan
- Negoi Ionut
- Nguyen Cuong Tat
- Nguyen Grant
- Nguyen Quyen Le
- Nguyen Trang Huyen
- Ningrum Dina Nur Anggraini
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- Nong Vuong Minh
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- Polinder Suzanne
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- Rahimi-Movaghar Vafa
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- Shackelford Katya Anne
- Shaheen Amira
- Shahraz Saeid
- Shaikh Masood Ali
- Shamsipour Mansour
- Shamsizadeh Morteza
- Sharma Jayendra
- Sharma Rajesh
- She Jun
- Shen Jiabin
- Shetty Balakrishna P.
- Shi Peilin
- Shibuya Kenji
- Shigematsu Mika
- Shiri Rahman
- Shiue Ivy
- Shrime Mark G.
- Sigfusdottir Inga Dora
- Silberberg Donald H.
- Silpakit Naris
- Silva Diego Augusto Santos
- Silva João Pedro
- Silveira Dayane Gabriele Alves
- Sindi Shireen
- Singh Abhishek
- Singh Jasvinder A.
- Singh Prashant Kumar
- Singh Virendra
- Sinha Dhirendra Narain
- Skiadaresi Eirini
- Sligar Amber
- Smith David L.
- Sobaih Badr H.A.
- Sobngwi Eugene
- Soneji Samir
- Soriano Joan B.
- Sreeramareddy Chandrashekhar T.
- Srinivasan Vinay
- Stathopoulou Vasiliki
- Steel Nicholas
- Stein Dan J.
- Steiner Caitlyn
- Stokes Mark Andrew
- Strong Mark
- Stöckl Heidi
- Sufiyan Muawiyyah Babale
- Suliankatchi Rizwan Abdulkader
- Sunguya Bruno F.
- Sur Patrick J.
- Swaminathan Soumya
- Sykes Bryan L.
- Szoeke Cassandra E.I.
- Tabarés-Seisdedos Rafael
- Tadakamadla Santosh Kumar
- Tadese Fentaw
- Tandon Nikhil
- Tanne David
- Tarajia Musharaf
- Tavakkoli Mohammad
- Taveira Nuno
- Tehrani-Banihashemi Arash
- Tekelab Tesfalidet
- Tekle Dejen Yemane
- Temam Shifa Girma
- Temsah Mohamad-Hani
- Terkawi Abdullah Sulieman
- Tesema Cheru Leshargie
- Tesssema Belay
- Theis Andrew
- Thomas Nihal
- Thompson Alex H.
- Thomson Alan J.
- Thrift Amanda G.
- Tiruye Tenaw Yimer
- Tobe-Gai Ruoyan
- Tonelli Marcello
- Topor-Madry Roman
- Topouzis Fotis
- Tortajada Miguel
- Tran Bach Xuan
- Truelsen Thomas
- Trujillo Ulises
- Tsilimparis Nikolaos
- Tuem Kald Beshir
- Tuzcu Emin Murat
- Tyrovolas Stefanos
- Ukwaja Kingsley Nnanna
- Undurraga Eduardo A.
- Uthman Olalekan A.
- Uzochukwu Benjamin S. Chudi
- Van Boven Job F.M.
- Varakin Yuri Y.
- Varughese Santosh
- Vasankari Tommi
- Vasconcelos Ana Maria Nogales
- Venketasubramanian Narayanaswamy
- Vidavalur Ramesh
- Violante Francesco S.
- Vishnu Abhishek
- Vladimirov Sergey K.
- Vlassov Vasiliy Victorovich
- Vollset Stein Emil
- Vos Theo
- Waid Jillian L.
- Wakayo Tolassa
- Wang Haidong
- Wang Yuan-Pang
- Weichenthal Scott
- Weiderpass Elisabete
- Weintraub Robert G.
- Werdecker Andrea
- Wesana Joshua
- Wijeratne Tissa
- Wilkinson James D.
- Wiysonge Charles Shey
- Woldeyes Belete Getahun
- Wolfe Charles D.A.
- Workicho Abdulhalik
- Workie Shimelash Bitew
- Xavier Denis
- Xu Gelin
- Yaghoubi Mohsen
- Yakob Bereket
- Yalew Ayalnesh Zemene
- Yan Lijing L.
- Yano Yuichiro
- Yaseri Mehdi
- Ye Pengpeng
- Yimam Hassen Hamid
- Yip Paul
- Yirsaw Biruck Desalegn
- Yonemoto Naohiro
- Yoon Seok-Jun
- Yotebieng Marcel
- Younis Mustafa Z.
- Zaidi Zoubida
- Zeeb Hajo
- Zenebe Zerihun Menlkalew
- Zerfu Taddese Alemu
- Zhang Anthony Lin
- Zhang Xueying
- Zodpey Sanjay
- Zuhlke Liesl Joanna
- Ärnlöv Johan
- Publication venue
- Publication date
- 01/01/2017
- Field of study
BACKGROUND: Detailed assessments of mortality patterns, particularly age-specific mortality, represent a crucial input that enables health systems to target interventions to specific populations. Understanding how all-cause mortality has changed with respect to development status can identify exemplars for best practice. To accomplish this, the Global Burden of Diseases, Injuries, and Risk Factors Study 2016 (GBD 2016) estimated age-specific and sex-specific all-cause mortality between 1970 and 2016 for 195 countries and territories and at the subnational level for the five countries with a population greater than 200 million in 2016.
METHODS: We have evaluated how well civil registration systems captured deaths using a set of demographic methods called death distribution methods for adults and from consideration of survey and census data for children younger than 5 years. We generated an overall assessment of completeness of registration of deaths by dividing registered deaths in each location-year by our estimate of all-age deaths generated from our overall estimation process. For 163 locations, including subnational units in countries with a population greater than 200 million with complete vital registration (VR) systems, our estimates were largely driven by the observed data, with corrections for small fluctuations in numbers and estimation for recent years where there were lags in data reporting (lags were variable by location, generally between 1 year and 6 years). For other locations, we took advantage of different data sources available to measure under-5 mortality rates (U5MR) using complete birth histories, summary birth histories, and incomplete VR with adjustments; we measured adult mortality rate (the probability of death in individuals aged 15-60 years) using adjusted incomplete VR, sibling histories, and household death recall. We used the U5MR and adult mortality rate, together with crude death rate due to HIV in the GBD model life table system, to estimate age-specific and sex-specific death rates for each location-year. Using various international databases, we identified fatal discontinuities, which we defined as increases in the death rate of more than one death per million, resulting from conflict and terrorism, natural disasters, major transport or technological accidents, and a subset of epidemic infectious diseases; these were added to estimates in the relevant years. In 47 countries with an identified peak adult prevalence for HIV/AIDS of more than 0·5% and where VR systems were less than 65% complete, we informed our estimates of age-sex-specific mortality using the Estimation and Projection Package (EPP)-Spectrum model fitted to national HIV/AIDS prevalence surveys and antenatal clinic serosurveillance systems. We estimated stillbirths, early neonatal, late neonatal, and childhood mortality using both survey and VR data in spatiotemporal Gaussian process regression models. We estimated abridged life tables for all location-years using age-specific death rates. We grouped locations into development quintiles based on the Socio-demographic Index (SDI) and analysed mortality trends by quintile. Using spline regression, we estimated the expected mortality rate for each age-sex group as a function of SDI. We identified countries with higher life expectancy than expected by comparing observed life expectancy to anticipated life expectancy on the basis of development status alone.
FINDINGS: Completeness in the registration of deaths increased from 28% in 1970 to a peak of 45% in 2013; completeness was lower after 2013 because of lags in reporting. Total deaths in children younger than 5 years decreased from 1970 to 2016, and slower decreases occurred at ages 5-24 years. By contrast, numbers of adult deaths increased in each 5-year age bracket above the age of 25 years. The distribution of annualised rates of change in age-specific mortality rate differed over the period 2000 to 2016 compared with earlier decades: increasing annualised rates of change were less frequent, although rising annualised rates of change still occurred in some locations, particularly for adolescent and younger adult age groups. Rates of stillbirths and under-5 mortality both decreased globally from 1970. Evidence for global convergence of death rates was mixed; although the absolute difference between age-standardised death rates narrowed between countries at the lowest and highest levels of SDI, the ratio of these death rates-a measure of relative inequality-increased slightly. There was a strong shift between 1970 and 2016 toward higher life expectancy, most noticeably at higher levels of SDI. Among countries with populations greater than 1 million in 2016, life expectancy at birth was highest for women in Japan, at 86·9 years (95% UI 86·7-87·2), and for men in Singapore, at 81·3 years (78·8-83·7) in 2016. Male life expectancy was generally lower than female life expectancy between 1970 and 2016, an
Finishing the euchromatic sequence of the human genome
- Author
- . Haifeng
- . Magner
- . Yin
- Abbott Scott
- Abbott-Ozersky Amanda
- Abdellah Zahra
- Abouelleil Amr
- Abrajano Anne
- Adachi Tamami
- Adam Catherine
- Adams Charles Q.
- Adamson Aaron
- Adekoya Emmanuel
- Adio-Oduola Babajide
- Aerts Andrea
- Aggarwal Arun
- Ahmadi Alireza
- Ahmed Shahana
- Aimable Matthew
- Ainscough Rachael
- Ait-Zahra Mostafa
- Aizu Tomoyuki
- Alcivare Dana
- Alegria Michelle
- Ali Alla
- Ali Johar
- Allegria-hartmann Michelle
- Alleman Jennifer
- Allen Carlana C.
- Allen Heather
- Allen Nicole R.
- Allen Susan
- Allen Thaddeus
- Almeida Jeff
- Almond Claire
- Alsbrooks Stephen L.
- Altherr Michael R.
- Amaratunge Harshinie C.
- Ambler Andrew
- Ambrose Karen
- Ambrose Kerrie
- Amemiya Chris
- Amico-Keller Gina
- Amin Amita G.
- Anderson Mechele
- Anderson Scott
- Anderson Scott
- Andora Janice
- Andredesz Carol
- Andrew Robert
- Andrews Dan
- Andrews Daniel
- Andrews Neil
- Andrews Stephanie
- Andriese Tim
- Anthouard Véronique
- Antonarakis Stylianos E.
- Anyalebechi Vivian
- Aoki Norie
- Apostolou Sinoula
- Apweiler Eva
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- Arai Rie
- Arbery Hazel
- Arcaina Marlon
- Arcaina Terisita
- Archer Beth
- Arellano Andre
- Arellano-Jones Perry
- Armbruster Jeff
- Armstrong Jon
- Arredondo Dilrukshi P.
- Arredondo Heather Hope
- Artiguenave François
- Asakawa Shuichi
- Asakawa Teruyo
- Ash Gareth
- Ashcroft Kevin
- Ashurst Jennifer
- Ashwell Robert
- Ashworth Linda K.
- Aslanidis Cara
- Asomugha Chinwe O.
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- Atkin Deborah
- Atkinson Andrea
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- Cao Ting
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- Cardenas Faviola
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- Carder Carol
- Carder Paul
- Carpenter Kelly
- Carrano Anthony V.
- Carriere Jason
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- Casias Kristal
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- Chen Xiaoyun
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- Chen Yanjiong
- Chen Yiyu
- Chen Zhu
- Chen Zhu
- Chen Zhu
- Cheng Jan-Fang
- Cheng Zhihua
- Chertkov Olga
- Cheshatsang Yama
- Chi Cheng
- Chi Han C.
- Chillingworth Neil
- Chin Sylvia
- Chinn Corey
- Chinwalla Asif
- Chissoe Stephanie
- Chiu Sally
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- Christensen Mari
- Christopoulos Constantine
- Chu Joseph
- Chui Connie
- Chung A
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- Cohn Judith D.
- Colayco Rick
- Cole Lotte
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- Collins John
- Collins Philip
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- Combs Jessie
- Comstock Robin
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- Cuomo Christina A.
- Curran Adam
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- Dawson Elisabeth
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- Ha Chi
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- Hagos Birhane
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- Hamilton Matt
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- Hamlett John
- Hammon Nancy
- Hammond Martin
- Hammond Sha
- Hammond Sian
- Hamza Khalid
- Han Guiqing
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- Hanak Vincent A.
- Hancock Julie
- Harbes Brandy A.
- Harding Adam
- Harkins C. Richard
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- Hashimoto Wakako
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- Haugen Eric
- Haussler David
- Havlak Paul
- Hawes Alicia C.
- Hawkins Ebere Sylvia Onyirioha
- Hawkins Natalie
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- Heyen Joshua
- Higgs Douglas
- Hildebrand Carl E.
- Hillier LaDeana
- Hillyard Guy
- Hines Sandra
- Hinkins Russell
- Hinrichs Angela S.
- Hitchens Matthew Edward
- Ho Issac
- Ho Sara-Jane
- Hodgson Anne V.
- Hodgson David
- Hoffman Susan M.G.
- Hoffs Michael
- Hogues Marilyn E.
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- Nakato Eriko
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- Nandkeshwar Richard
- Nankervis Colin E.
- Naranjo Cleo M.
- Nash William
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- Nwokenkwo Stanley
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- Okumura Reina
- Okwuonu Geoffrey O.
- Okwuonu Kenneth C.
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- Zeng Yixin
- Zhai Dong
- Zhan Guoping
- Zhang Bo
- Zhang Caimin
- Zhang Fengmei
- Zhang Guangyu
- Zhang Guohua
- Zhang Guohua
- Zhang Haiqing
- Zhang Haiqing
- Zhang Haiqing
- Zhang Hongbo
- Zhang Hongbo
- Zhang Jingjing
- Zhang Jingjing
- Zhang Jingkun
- Zhang Jiuchun
- Zhang Jiuchun
- Zhang Lanzhi
- Zhang Li
- Zhang Li
- Zhang Meihua
- Zhang Meng
- Zhang Ming
- Zhang Qing
- Zhang Ruhua
- Zhang Shaojie
- Zhang Tiezhen
- Zhang Wei
- Zhang Wei
- Zhang Xianglin
- Zhang Xianglin
- Zhang Xiaoliang
- Zhang Xiuqing
- Zhang Yan
- Zhang Yi
- Zhang Yilin
- Zhang Yilin
- Zhang Ying
- Zhang Yuansen
- Zhang Yuzhi
- Zhang Zhengdong
- Zhao Hongmei
- Zhao Lijian
- Zhao Shenru
- Zhao Zhijing
- Zhen Zhicheng
- Zheng Haibo
- Zhong Ming
- Zhou Carol
- Zhou Haixia
- Zhou Jianling
- Zhou Nannan
- Zhou Xinfeng
- Zhou Yan
- Zhou Yang
- Zhou Yi
- Zhu Bingying
- Zhu Bofeng
- Zhu Fenghua
- Zhu Genfeng
- Zhu Genfeng
- Zhu Miao
- Zhu Ning
- Zhu Yongge
- Zhu Zhen
- Zhuang Shitao
- Zierten Deborah
- Zimmer Andrew
- Zody Michael C.
- Zollo Massimo
- Zorrilla Sara E.
- Zuo Lin
- Publication venue
- LSU Digital Commons
- Publication date
- 21/10/2004
- Field of study
The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead
Search for gravitational-lensing signatures in the full third observing run of the LIGO-Virgo network
- Author
- Abbott R.
- Abe H.
- Acernese F.
- Ackley Kendall
- Adhicary S.
- Adhikari Naresh
- Adhikari Rana X.
- Adkins V. K.
- Adya V. B.
- Affeldt C.
- Agarwal D.
- Agathos Michalis
- Aguiar Odylio D.
- Aiello Lorenzo
- Ain A.
- Ajith Parameswaran
- Akutsu Tomotada
- Albanesi S.
- Alfaidi R. A.
- Allocca Annalisa
- Alléné C.
- Altin Paul
- Amato Alex
- Anand S.
- Ananyeva A.
- Anderson Stuart
- Anderson Warren G.
- Ando M.
- Andrade T.
- Andrea Prodi Giovanni
- Andres Nicolas
- Andric Tomislav
- Andrés-Carcasona Marc
- Anne Bizouard Marie
- Ansoldi S.
- Antelis Javier M.
- Antier Sarah
- Antonio Font Roda Jose
- Apostolatos T.
- Appavuravther E. Z.
- Appert S.
- Apple S. K.
- Arai Koji
- Araya Akito
- Araya Melody
- Areeda Joseph
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- Aronson S. M.
- Arène M.
- Asada Hideki
- Ashton Gregory
- Aso Yoichi
- Assiduo M.
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- Chalathadka Subrahmanya Shreevathsa
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- Charlton Philip
- CHASSANDE-MOTTIN Eric
- Chatterjee Chayan
- Chatterjee Debarati
- Chatterjee Deep
- Chaturvedi M.
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- Chatziioannou Katerina
- Chen ChianShu
- Chen Dan
- Chen Hsin-Yu
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- Christensen Nelson
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- Corsi Alessandra
- Cortese Stefano
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- Coulon J. -P.
- Countryman S. T.
- Cousins Bryce
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- Dasgupta A.
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- Dax Maximilian
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- Dhurandhar S.
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- Takahashi Hirotaka
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- Takeda Hiroki
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- Talbot C.
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- Tao Liu
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- tiwari vaibhav
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- Xiao Liting
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- Yamamoto Kazuhiro
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- Yang Y. -C.
- Yang Yang
- Yang Yi
- Yap M. J.
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- Yeh S. -W.
- Yelikar A. B.
- Yokoyama Jun'ichi
- Yokozawa T.
- Yoo Jooheon
- Yoshioka T.
- Yu Hang
- Yu Haocun
- Yuzurihara H.
- Zadrożny A.
- Zahoor Jan Aasim
- Zanolin M.
- Zeidler Simon
- Zelenova T.
- Zendri J. -P.
- Zevin Michael
- Zhan M.
- Zhang H.
- Zhang Jue
- Zhang L.
- Zhang Rui
- Zhang T.
- Zhang Y.
- Zhao C.
- Zhao G.
- Zhao Yue
- Zhao Yuhang
- Zheng Yanyan
- Zhou R.
- Zhu Xingjiang
- Zhu Zong-Hong
- Zimmerman Aaron
- Zucker M. E.
- Árpád Gergely László
- 劉 國欽
- 曹周键
- 王谨
- 都丸 隆行
- Publication venue
- Publication date
- 01/04/2023
- Field of study
Gravitational lensing by massive objects along the line of sight to the source causes distortions of gravitational wave-signals; such distortions may reveal information about fundamental physics, cosmology and astrophysics. In this work, we have extended the search for lensing signatures to all binary black hole events from the third observing run of the LIGO--Virgo network. We search for repeated signals from strong lensing by 1) performing targeted searches for subthreshold signals, 2) calculating the degree of overlap amongst the intrinsic parameters and sky location of pairs of signals, 3) comparing the similarities of the spectrograms amongst pairs of signals, and 4) performing dual-signal Bayesian analysis that takes into account selection effects and astrophysical knowledge. We also search for distortions to the gravitational waveform caused by 1) frequency-independent phase shifts in strongly lensed images, and 2) frequency-dependent modulation of the amplitude and phase due to point masses. None of these searches yields significant evidence for lensing. Finally, we use the non-detection of gravitational-wave lensing to constrain the lensing rate based on the latest merger-rate estimates and the fraction of dark matter composed of compact objects
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