From Bare Metal to Virtual: Lessons Learned when a Supercomputing Institute Deploys its First Cloud

As primary provider for research computing services at the University of Minnesota, the Minnesota Supercomputing Institute (MSI) has long been responsible for serving the needs of a user-base numbering in the thousands. In recent years, MSI---like many other HPC centers---has observed a growing need for self-service, on-demand, data-intensive research, as well as the emergence of many new controlled-access datasets for research purposes. In light of this, MSI constructed a new on-premise cloud service, named Stratus, which is architected from the ground up to easily satisfy data-use agreements and fill four gaps left by traditional HPC. The resulting OpenStack cloud, constructed from HPC-specific compute nodes and backed by Ceph storage, is designed to fully comply with controls set forth by the NIH Genomic Data Sharing Policy. Herein, we present twelve lessons learned during the ambitious sprint to take Stratus from inception and into production in less than 18 months. Important, and often overlooked, components of this timeline included the development of new leadership roles, staff and user training, and user support documentation. Along the way, the lessons learned extended well beyond the technical challenges often associated with acquiring, configuring, and maintaining large-scale systems.Comment: 8 pages, 5 figures, PEARC '18: Practice and Experience in Advanced Research Computing, July 22--26, 2018, Pittsburgh, PA, US

The Clinical Importance of the Heterogeneity of HER2 neu

We report on a patient with breast cancer in whom there were areas of the tumor that were 3+ positive and negative for HER2 neu by immunohistochemistry, adjacent to each other. Depending on the area tested the results were completely different. The clinical implications are important. We recommend retesting a large portion of the tumor in all cases of initially negative test results

New Digital Ways of Delivering Sex Education: A Practice Perspective

This article explores new, under-researched genres of sex education for adolescents in sub-Saharan Africa resulting from access to the internet through mobile phones. It examines the history of developing online health information platforms tailored for youth through the experiences of digital developers and the reflections of users. Unlike traditional sources of sex education, the internet offers portability, anonymity, informality, ‘personalised’ responses, and the ability to interact with peers who are not local or part of face-to-face networks. This article draws on a literature review, complemented by qualitative and quantitative material generated by Every1Mobile in its production of online health communities for young people. We found massive enthusiasm for online sex education in Africa but little knowledge about how young people use, perceive and respond to this. We recommend that practitioners, funders and researchers invest more in understanding not only the many fantastic opportunities associated with digital sexual and reproductive health and rights (SRHR) information, but also the interwoven contradictions, challenges and potential for misuse

Rancang Bangun Sistem Informasi Akademik Fakultas Matematika Dan Ilmu Pengetahuan Alam Berbasis Website

A website based academic information system is indispensable for processing academic data such as processing data on subjects, grades, filling study plan cards, thus supporting the achievement of the vision, mission and academic goals of the Faculty of Mathematics and Natural Sciences, one of which is to provide education by optimizing the use of Information and Communication. Technology (ICT) for academic services. In designing the Academic Information System for the Faculty of Mathematics and Natural Sciences, this Website-Based uses the waterfall method with stages, Requirements Definition, System and Software Design, Implementation and Unit Testing, Integration and System Testing, Operation and Maintenance. The software used in building this website is Visual Studio Code, MySQL, and XAMPP. This website has been tested with blackbox testing which results that the features on the website can run well. Website-Based Design of Academic Information Systems for the Faculty of Mathematics and Natural Sciences This website was developed as an information medium that facilitates information such as study plan card data, study result cards, and class schedules that can facilitate lecturers and students in seeing the academic activities they carry out

2005-2006 Young Musicians Competition - Winds, Brass, and Percussion

Sponsored by Jim and Bette Cumpton Competition Coordinator Marc Reese, Lynn University Conservatory of Music Jury Christina Burr, Artist Faculty David Cole, Artist Faculty Michael Ellerthttps://spiral.lynn.edu/conservatory_other-competitions/1003/thumbnail.jp

The Effects of Antimicrobial Mouthwashes on Systemic Disease: What Is the Evidence?

The potential association between antimicrobial mouthwash use and systemic health has gained attention in recent years with reports highlighting how some common systemic conditions are influenced by the use of different types of mouthwashes. In this context, links between mouthwash use and cardiovascular disease, diabetes mellitus, oral cancer, Alzheimer's disease, and preeclampsia have been proposed, albeit with limited levels of evidence. Chlorhexidine mouthwash in particular has been the most widely studied agent while available data on other types of over-the-counter mouthwashes are generally scarce. Furthermore, there is currently no evidence-based recommendations on the appropriate use of mouthwashes during pregnancy. This article will present the current evidence on the association between mouthwash use and the aforementioned conditions with emphasis on the mechanisms that may underlie such an association