8,392 research outputs found
Cell therapy in patients with critical limb ischemia
Critical limb ischemia (CLI) represents the most advanced stage of peripheral arterial obstructive disease (PAOD) with a severe obstruction of the arteries which markedly reduces blood flow to the extremities and has progressed to the point of severe rest pain and/or even tissue loss. Recent therapeutic strategies have focused on restoring this balance in favor of tissue survival using exogenousmolecular and cellular agents to promote regeneration of the vasculature.These are based on stimulation of angiogenesis by extracellular and cellular components. This review article carries out a systematic analysis of the most recent scientific literature on the application of stem cells in patients with CLI. The results obtained from the detailed analysis of the recent literature data have confirmed the beneficial role of cell therapy in reducing the rate of major amputations in patients with CLI and improving their quality of life
Hlt1 Muon Alley Description
This note describes the LHCb Hlt1 muon alley, which is part of the High Level Trigger. It is intended to confirm the L0 muon trigger and reduce the bandwidth. The performance presented here is done using about 1000 simulated data of some relevant muon channels and 200k of minimum bias events
An energetic blast wave from the December 27 giant flare of the soft gamma-ray repeater 1806-20
Recent follow-up observations of the December 27 giant flare of SGR 1806-20
have detected a multiple-frequency radio afterglow from 240 MHz to 8.46 GHz,
extending in time from a week to about a month after the flare. The angular
size of the source was also measured for the first time. Here we show that this
radio afterglow gives the first piece of clear evidence that an energetic blast
wave sweeps up its surrounding medium and produces a synchrotron afterglow, the
same mechanism as established for gamma-ray burst afterglows. The optical
afterglow is expected to be intrinsically as bright as at t\la
0.1 days after the flare, but very heavy extinction makes the detection
difficult because of the low galactic latitude of the source. Rapid infrared
follow-up observations to giant flares are therefore crucial for the
low-latitude SGRs, while for high-latitude SGRs (e.g. SGR 0526-66), rapid
follow-ups should result in identification of their possible optical
afterglows. Rapid multi-wavelength follow-ups will also provide more detailed
information of the early evolution of a fireball as well as its composition.Comment: Updated version, accepted for publication in ApJ Letter
Spin-glass state and long-range magnetic order in Pb(Fe1/2Nb1/2)O3
We have investigated the magnetic ground-state of the multiferroic relaxor
ferroelectric \pfn with SR spectroscopy and neutron scattering. We find
that a transition to a partially disordered phase occurs below T=20 K that
coexists with long-range antiferromagnetic ordering. The disordered phase
resembles a spin-glass. No clustering of magnetic ions could be evidenced by
SR so that the coexistence appears homogeneous in the sample
Proximity effects in the superconductor / heavy fermion bilayer system Nb / CeCu_6
We have investigated the proximity effect between a superconductor (Nb) and a
'Heavy Fermion' system (CeCu_6) by measuring critical temperatures and
parallel critical fields H_{c2}^{\parallel}(T) of Nb films with varying
thickness deposited on 75 nm thick films of CeCu_6, and comparing the results
with the behavior of similar films deposited on the normal metal Cu. For Nb on
CeCu_6 we find a strong decrease of T_c with decreasing Nb thickness and a
finite critical thickness of the order of 10 nm. Also, dimensional crossovers
in H_{c2}^{\parallel}(T) are completely absent, in strong contrast with Nb/Cu.
Analysis of the data by a proximity effect model based on the Takahashi-Tachiki
theory shows that the data can be explained by taking into account both the
high effective mass (or low electronic diffusion constant), {\it and} the large
density of states at the Fermi energy which characterize the Heavy Fermion
metal.Comment: 7 pages, 2 figure. Manuscript has been submitted to a refereed
journa
Spin dynamics and disorder effects in the S=1/2 kagome Heisenberg spin liquid phase of kapellasite
We report Cl NMR, ESR, SR and specific heat measurements on the
frustrated kagom\'e magnet kapellasite,
CuZn(OH)Cl, where a gapless spin liquid phase is
stabilized by a set of competing exchange interactions. Our measurements
confirm the ferromagnetic character of the nearest-neighbour exchange
interaction and give an energy scale for the competing interactions K. The study of the temperature-dependent ESR lineshift reveals a
moderate symmetric exchange anisotropy term , with %. These
findings validate a posteriori the use of the Heisenberg
model to describe the magnetic properties of kapellasite [Bernu et al., Phys.
Rev. B 87, 155107 (2013)]. We further confirm that the main deviation from this
model is the severe random depletion of the magnetic kagom\'e lattice by 27%,
due to Cu/Zn site mixing, and specifically address the effect of this disorder
by Cl NMR, performed on an oriented polycrystalline sample.
Surprisingly, while being very sensitive to local structural deformations, our
NMR measurements demonstrate that the system remains homogeneous with a unique
spin susceptibility at high temperature, despite a variety of magnetic
environments. Unconventional spin dynamics is further revealed by NMR and
SR in the low-, correlated, spin liquid regime, where a broad
distribution of spin-lattice relaxation times is observed. We ascribe this to
the presence of local low-energy modes.Comment: 15 pages, 11 figures. To appear in Phys. Rev.
Superconductivity and magnetism in RbxFe2-ySe2: Impact of thermal treatment on mesoscopic phase separation
An extended study of the superconducting and normal-state properties of
various as-grown and post-annealed RbxFe2-ySe2 single crystals is presented.
Magnetization experiments evidence that annealing of RbxFe2-ySe2 at 413 K, well
below the onset of phase separation Tp=489 K, neither changes the magnetic nor
the superconducting properties of the crystals. In addition, annealing at 563
K, well above Tp, suppresses the superconducting transition temperature Tc and
leads to an increase of the antiferromagnetic susceptibility accompanied by the
creation of ferromagnetic impurity phases, which are developing with annealing
time. However, annealing at T=488K=Tp increases Tc up to 33.3 K, sharpens the
superconducting transition, increases the lower critical field, and strengthens
the screening efficiency of the applied magnetic field. Resistivity
measurements of the as-grown and optimally annealed samples reveal an increase
of the upper critical field along both crystallographic directions as well as
its anisotropy. Muon spin rotation and scanning transmission electron
microscopy experiments suggest the coexistence of two phases below Tp: a
magnetic majority phase of Rb2Fe4Se5 and a non-magnetic minority phase of
Rb0.5Fe2Se2. Both microscopic techniques indicate that annealing the specimens
just at Tp does not affect the volume fraction of the two phases, although the
magnetic field distribution in the samples changes substantially. This suggests
that the microstructure of the sample, caused by mesoscopic phase separation,
is modified by annealing just at Tp, leading to an improvement of the
superconducting properties of RbxFe2-ySe2 and an enhancement of Tc.Comment: 13 pages, 12 figure
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