Whatever happened to biological thinking in urban planning?

Since 2007 the proclamation of the ‘urban age’ by the UN has been heralded as a critical moment in human society and history. The ‘urban’ has taken its place alongside the anthropocene as a new era for humanity. Its importance as a transformational moment has been underscored by scientific interest in cities. Anxiety about urbanisation was a motivator for early town planning activity in the 19th century. The tools developed by different disciplines to solve the crisis of 19th century urban development were designed around human welfare needs. With our cities forming both the origin and the solution to our planetary environmental crisis, a broader set of planning thoughts, languages and metaphors are needed that go beyond the mere human. Thinking biologically about Homo Sapiens in cities will be critical to our survival.   Planning history has a role to play in this project, drawing on the past to identify a biological lineage in urban planning and reveal what has and has not been successful. The aim of this paper is to start that identification. It forms part of a larger project to trace a lineage of biological thinking in urban planning history during the twentieth century. The paper analyses and reinterprets the use of science and biology by two influential planning visionaries: Sir Patrick Geddes (1854-1932) and Le Corbusier (CharlesÉdouard Jeanneret, 1887-1965). Among the luminaries of his age, Geddes as a biologist turned sociologist was a unique figure. He attempted to grapple with the early 20th century urban age in biological terms. Le Corbusier, also used science and biology to argue for universal rules to guide urbanism and as an aesthetic. The paper describes the biological work of these canonical planning thinkers to consider why humanism became the hegemonic frame for urban planning in the twentieth century

New measurements of Ωm\Omega_m from gamma-ray bursts

Context: Data from cosmic microwave background radiation (CMB), baryon acoustic oscillations (BAO), and supernovae Ia (SNe-Ia) support a constant dark energy equation of state with $w_0 \sim -1$. Measuring the evolution of $w$ along the redshift is one of the most demanding challenges for observational cosmology. Aims: We discuss the existence of a close relation for GRBs, named Combo-relation, based on characteristic parameters of GRB phenomenology such as the prompt intrinsic peak energy $E_{p,i}$, the X-ray afterglow, the initial luminosity of the shallow phase $L_0$, the rest-frame duration $\tau$ of the shallow phase, and the index of the late power-law decay $\alpha_X$. We use it to measure $\Omega_m$ and the evolution of the dark energy equation of state. We also propose a new calibration method for the same relation, which reduces the dependence on SNe Ia systematics. Methods: We have selected a sample of GRBs with 1) a measured redshift $z$; 2) a determined intrinsic prompt peak energy $E_{p,i}$, and 3) a good coverage (0.3-10) keV afterglow light curves. The fitting technique of the rest.frame (0.3-10) keV luminosity light curves represents the core of the Combo-relation. We separate the early steep decay, considered a part of the prompt emission, from the X-ray afterglow additional component. Data with the largest positive residual, identified as flares, are automatically eliminated until the p-value of the fit becomes greater than 0.3. Results: We strongly minimize the dependency of the Combo-GRB calibration on SNe Ia. We also measure a small extra-Poissonian scatter of the Combo-relation, which allows us to infer from GRBs alone $\Omega_M =0.29^{+0.23}_{-0.15}$ (1$\sigma$) for the $\Lambda$CDM cosmological model, and $\Omega_M =0.40^{+0.22}_{-0.16}$, $w_0 = -1.43^{+0.78}_{-0.66}$ for the flat-Universe variable equation of state case.Comment: 10 pages, 9 figures, 3 tables. Accepted for publication in A&A. Truncated abstract tex

Exploring E-Planning Practices in Different Contexts

As planners and decision-makers experiment with information and communication technologies (ICTs),it’s important to explore and analyze these attempts in different planning systems and contexts. The aim of the article is to compare the use of and aspirations attached to e-planning in Helsinki, Finland and Sydney,Australia. This comparison will highlight the interrelationship between planning context and its amenability to an e-planning approach and shows there are shared themes in both cases: firstly, the complexity involved in reconciling the aims of the e-planning experiments and their connection to the planning process itself (roles,objectives, implementation of tools and processes). Secondly, the way that e-planning opens up cracks in the façade of administration, and thirdly, the ways in which e-planning provides possibilities to reshape existing planning procedures. The authors argue that the different planning and governance contexts affect the adoption of e-planning and this adoption is necessarily a selective process.Peer reviewe

Addressing the circularity problem in the Ep−EisoE_\text{p}-E_\text{iso} correlation of Gamma-Ray Bursts

We here propose a new model-independent technique to overcome the circularity problem affecting the use of Gamma-Ray Bursts (GRBs) as distance indicators through the use of $E_{\rm p}$--$E_{\rm iso}$ correlation. We calibrate the $E_{\rm p}$--$E_{\rm iso}$ correlation and find the GRB distance moduli that can be used to constrain dark energy models. We use observational Hubble data to approximate the cosmic evolution through B\'ezier parametric curve obtained through the linear combination of Bernstein basis polynomials. In so doing, we build up a new data set consisting of 193 GRB distance moduli. We combine this sample with the supernova JLA data set to test the standard $\Lambda$CDM model and its $w$CDM extension. We place observational constraints on the cosmological parameters through Markov Chain Monte Carlo numerical technique. Moreover, we compare the theoretical scenarios by performing the AIC and DIC statistics. For the $\Lambda$CDM model we find $\Omega_m=0.397^{+0.040}_{-0.039}$ at the $2\sigma$ level, while for the $w$CDM model we obtain $\Omega_m=0.34^{+0.13}_{-0.15}$ and $w=-0.86^{+0.36}_{-0.38}$ at the $2\sigma$ level. Our analysis suggests that $\Lambda$CDM model is statistically favoured over the $w$CDM scenario. No evidence for extension of the $\Lambda$CDM model is found.Comment: 7 pages, 4 figure

A Statistical Interpretation of Space and Classical-Quantum duality

By defining a prepotential function for the stationary Schr\"odinger equation we derive an inversion formula for the space variable $x$ as a function of the wave-function $\psi$. The resulting equation is a Legendre transform that relates $x$, the prepotential ${\cal F}$, and the probability density. We invert the Schr\"odinger equation to a third-order differential equation for ${\cal F}$ and observe that the inversion procedure implies a $x$-$\psi$ duality. This phenomenon is related to a modular symmetry due to the superposition of the solutions of the Schr\"odinger equation. We propose that in quantum mechanics the space coordinate can be interpreted as a macroscopic variable of a statistical system with $\hbar$ playing the role of a scaling parameter. We show that the scaling property of the space coordinate with respect to $\tau=\partial_{\psi}^2{\cal F}$ is determined by the ``beta-function''. We propose that the quantization of the inversion formula is a natural way to quantize geometry. The formalism is extended to higher dimensions and to the Klein-Gordon equation.Comment: 11 pages. Standard Latex. Final version to appear in Physical Review Letters. Revised and extended version. The formalism is extended to higher dimensions and to the Klein-Gordon equation. A possible connection with string theory is considered. The $x-\psi$ duality is emphasized by a minor change in the title. The new title is: Duality of $x$ and $\psi$ and a statistical interpretation of space in quantum mechanic

Design and Optimization of an Active Leveling System Actuator for Lunar Lander Application

This work proposes a systematic methodology for designing an active leveling system (ALS) actuator for lunar landing application. The ALS actuator is integrated into an inverted tripod leg layout, exploiting a honeycomb crushable damper as a shock absorber. The proposed ALS actuator is fitted within the leg’s primary strut and features a custom permanent-magnet synchronous machine rigidly coupled with a lead screw. The actuator aims to both provide proper leg deployment functioning and compensate for the different shock absorber deformations during landing. The leg dynamic behavior is simulated through a parameterized multi-body model to investigate different landing scenarios. First, a parametric sensitivity approach is used to optimize the transmission system and the electric machine characteristics. Then, the electric motor model is numerically validated and optimized through electromagnetic finite element analysis. To validate the proposed ALS design methodology, a virtual test bench is used to assess the ALS performances under different load scenarios. It is found that the proposed methodology is able to yield a compact, well-sized actuator which is numerically validated with the EL3 platform as a case study

INSPEcT: a computational tool to infer mRNA synthesis, processing and degradation dynamics from RNA- and 4sU-seq time course experiments.

Abstract Motivation: Cellular mRNA levels originate from the combined action of multiple regulatory processes, which can be recapitulated by the rates of pre-mRNA synthesis, pre-mRNA processing and mRNA degradation. Recent experimental and computational advances set the basis to study these intertwined levels of regulation. Nevertheless, software for the comprehensive quantification of RNA dynamics is still lacking. Results: INSPEcT is an R package for the integrative analysis of RNA- and 4sU-seq data to study the dynamics of transcriptional regulation. INSPEcT provides gene-level quantification of these rates, and a modeling framework to identify which of these regulatory processes are most likely to explain the observed mRNA and pre-mRNA concentrations. Software performance is tested on a synthetic dataset, instrumental to guide the choice of the modeling parameters and the experimental design. Availability and implementation: INSPEcT is submitted to Bioconductor and is currently available as Supplementary Additional File S1. Contact: [email protected] Supplementary Information: Supplementary data are available at Bioinformatics online

Hunting dogs as sentinel animals for monitoring infections with Trichinella spp. in wildlife

Nematode parasites of the genus Trichinella are important foodborne pathogens transmitted by ingestion of striated muscles harbouring infective larvae. Wild carnivorous and omnivorous animals are the most important reservoirs of these parasites. Hunting activities play an important role in Trichinella spp