10 research outputs found

    A Comparative Analysis of Factor Effecting the Buying Judgement of Smart Phone

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    Smart phone has various utilizations to various clients as per their necessities. With sensational rise in the usage of smart phone the individuals are considering different factors while purchasing a smart phone. This paper has put endeavor to reveal the fundamental factors which effect clients in picking up of the smart phone. A sample of 512 responses was taken through questionnaire. An organized questionnaire was planned with five point Likert scale was utilized to meeting respondent’s .Factor analysis and descriptive statistical tools were applied to extricate the basic variables influence cell phone acquiring choice. The result shows that the most important factors are physical attributes, apps and sounds while the less importance is given to other factors such as convenience, price which can also vary by age, service and gender. The future scope of this paper lies in the fact that whether age, occupation, gender makes any difference in purchasing decision of smart phone

    Opinion mining framework using proposed RB-bayes model for text classication

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    Information mining is a capable idea with incredible potential to anticipate future patterns and conduct. It alludes to the extraction of concealed information from vast data sets by utilizing procedures like factual examination, machine learning, grouping, neural systems and genetic algorithms. In naive baye’s, there exists a problem of zero likelihood. This paper proposed RB-Bayes method based on baye’s theorem for prediction to remove problem of zero likelihood. We also compare our method with few existing methods i.e. naive baye’s and SVM. We demonstrate that this technique is better than some current techniques and specifically can analyze data sets in better way. At the point when the proposed approach is tried on genuine data-sets, the outcomes got improved accuracy in most cases. RB-Bayes calculation having precision 83.333

    What questions do patients undergoing lower extremity joint replacement surgery have?

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    BACKGROUND: The value of the Internet to deliver preoperative education would increase if there was variability in questions patients want answered. This study's goal was to have patients consulting an orthopedic surgeon about undergoing either a total hip arthroplasty (THA) or a total knee arthroplasty (TKA) rate the importance of different questions concerning their care. METHODS: We assembled questions patients might have about joint replacement surgery by analyzing the literature and querying a pilot group of patients and surgeons. Twenty-nine patients considering undergoing THA and 19 patients considering TKR completed a written survey asking them to rate 30 different questions, with a 5 point Likert scale from 1 (least important) – 5 (most important). RESULTS: For patients considering THA or TKR, the 4 highest rated questions were: Will the surgery affect my abilities to care for myself?, Am I going to need physical therapy?, How mobile will I be after my surgery?, When will I be able to walk normally again? The mean percentage disagreement was 42% for questions answered by TKR patients and 47% for the THA group. Some patients gave a high rating to questions lowly rated by the rest of the group. CONCLUSIONS: Although there was enough agreement to define a core set of questions that should be addressed with most patients considering THA or TKA, some of the remaining questions were also highly important to some patients. The Web may offer a flexible medium for accommodating this large variety of information needs

    Terphenyl derivatives as “turn on” fluorescent sensors for mercury

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    New terphenyl-based reversible receptors 1−4 with pyrene and quinoline as the fluorophores have been designed, synthesized, and examined for their cation recognition abilities toward various cations (Sm3+, Nd3+, Pb2+, Hg2+, Ba2+, Cd2+, Ag+, Zn2+, Cu2+, Ni2+, Co2+, Fe2+, Fe3+, K+, Mg2+, Na+, and Li+) by UV−vis, fluorescence, and NMR spectroscopy. The prepared receptors showed the highly selective and sensitive “Off−On” fluorescence signaling behavior for Hg2+ ions in THF and mixed aqueous media (THF:H2O, 9.5:0.5)

    Underwater Endoscopic Mucosal Resection for 10 mm or Larger Nonpedunculated Colorectal Polyps: A Systematic Review and Meta-Analysis

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    Background/Aims Recent studies have reported the favorable outcomes of underwater endoscopic mucosal resection (UEMR) for colorectal polyps. We performed a systematic review and meta-analysis evaluating the efficacy and safety of UEMR for nonpedunculated polyps ≥10 mm. Methods We performed a comprehensive search of multiple databases (through May 2020) to identify studies reporting the outcomes of UEMR for ≥10 mm nonpedunculated colorectal polyps. The assessed outcomes were recurrence rate on the first follow-up, en bloc resection, incomplete resection, and adverse events after UEMR. Results A total of 1276 polyps from 16 articles were included in our study. The recurrence rate was 7.3% (95% confidence interval [CI], 4.3–12) and 5.9% (95% CI, 3.6–9.4) for nonpedunculated polyps ≥10 and ≥20 mm, respectively. For nonpedunculated polyps ≥10 mm, the en bloc resection, R0 resection, and incomplete resection rates were 57.7% (95% CI, 42.4–71.6), 58.9% (95% CI, 42.4–73.6), and 1.5% (95% CI, 0.8–2.6), respectively. The rates of pooled adverse events, intraprocedural bleeding, and delayed bleeding were 7.0%, 5.4%, and 2.9%, respectively. The rate of perforation and postpolypectomy syndrome was 0.8%. Conclusions Our systematic review and meta-analysis demonstrates that UEMR for nonpedunculated colorectal polyps ≥10 mm is safe and effective with a low rate of recurrence

    Data_Sheet_2_Unveiling APOL1 haplotypes in a predominantly African-American cohort of kidney transplant patients: a novel classification using probe-independent quantitative real-time PCR.PDF

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    IntroductionApolipoprotein-L1 (APOL1) is a primate-specific protein component of high-density lipoprotein (HDL). Two variants of APOL1 (G1 and G2), provide resistance to parasitic infections in African Americans but are also implicated in kidney-related diseases and transplant outcomes in recipients. This study aims to identify these risk variants using a novel probe-independent quantitative real-time PCR method in a high African American recipient cohort. Additionally, it aims to develop a new stratification approach based on a haplotype-centric model.MethodsGenomic DNA was extracted from recipient PBMCs using SDS lysis buffer and proteinase K. A quantitative PCR assay with modified forward primers and a common reverse primer enabled us to quantitatively identify single nucleotide polymorphisms (SNPs) and the 6-bp deletion. Additionally, we used Sanger sequencing to verify our QPCR findings.ResultsOur novel probe-independent qPCR effectively distinguished homozygous wild-type, heterozygous SNPs/deletions, and homozygous SNPs/deletions, with at least 4-fold differences. A high prevalence of APOL1 variants was observed (18% two-risk alleles, 34% one-risk allele) in our recipient cohort. Intriguingly, no significant impact of recipient APOL1 variants on transplant outcomes was observed up to 12-month of follow-ups. Ongoing research will encompass more time points and a larger patient cohort, allowing for a comprehensive evaluation of G1/G2 variant subgroups categorized by new haplotype scores, enriching our understanding.ConclusionOur cost-effective and rapid qPCR technique facilitates APOL1 genotyping within hours. Prospective and retrospective studies will enable comparisons with long-term allograft rejection, potentially predicting early/late-stage transplant outcomes based on haplotype evaluation in this diverse group of kidney transplant recipients.</p
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