335 research outputs found
False positives on neuropsychological measures of effort among bilingual neurologically intact Mexican Americans
The present study examines the performance of bilingual Mexican Americans on neuropsychological measures of effort in language and visual-perceptual formats. Optimal/suboptimal effort cutoff scores derived from monolingual English Speakers were used to test participants divided by language of administration and bilingual groupings based upon Spanish-English difference scores on the Woodcock Munoz Language Survey-Revised Picture Vocabulary subtest. Participants produced more false positives (misidentification of suboptimal effort) on the Reliable Digit Span, a language formatted measure, and similar rates of false positives on visual-perceptual effort measures: Test of Memory Malingering and the Dot Counting Test as compared to established rates using monolingual English speakers. Results show that the Test of Memory Malingering and Dot Counting Test are appropriate for this linguistically diverse population while the Reliable Digit Span is not. These results show why linguistically diverse groups can be misdiagnosed as giving poor effort when the tests being used are not appropriate
Human skeletal remains of the ancient Maya in the caves of Dos Pilas, Guatemala
This study focuses on the assessment of the depositional activity that occurred in six caves of the Petexbatun region of the Peten, Guatemala through a quantitative analysis of the human skeletal material recovered from them. Five of these caves are associated with the site of Dos Pilas; the sixth cave (Cueva de Los Quetzales) is located beneath the site of Las Pacayas. The cave is an important aspect of the Maya worldview, as evidenced in the artifactual and skeletal material found in caves by archaeological exploration. My study is specifically focused on the assessment of the primary and/or secondary burial of Maya dead within these caves via analyses of the relative skeletal element frequencies, the minimum and probable number of individuals, and the identification of human cut marks. Based on these lines of evidence and data from preliminary reports, between 100 and 150 individuals of both sexes and various age groups were primarily deposited/buried in these caves. Secondary activity may be inferred based on evidence of human-made cut marks on several elements. There is no osteological evidence to support the hypothesis of human sacrifice. I was unable to determine the status of the individuals deposited in the caves. The best interpretation is that several types of depositional activity occurred within these caves over time
Human skeletal remains of the ancient Maya in the caves of Dos Pilas, Guatemala
This study focuses on the assessment of the depositional activity that occurred in six caves of the Petexbatun region of the Peten, Guatemala through a quantitative analysis of the human skeletal material recovered from them. Five of these caves are associated with the site of Dos Pilas; the sixth cave (Cueva de Los Quetzales) is located beneath the site of Las Pacayas. The cave is an important aspect of the Maya worldview, as evidenced in the artifactual and skeletal material found in caves by archaeological exploration. My study is specifically focused on the assessment of the primary and/or secondary burial of Maya dead within these caves via analyses of the relative skeletal element frequencies, the minimum and probable number of individuals, and the identification of human cut marks. Based on these lines of evidence and data from preliminary reports, between 100 and 150 individuals of both sexes and various age groups were primarily deposited/buried in these caves. Secondary activity may be inferred based on evidence of human-made cut marks on several elements. There is no osteological evidence to support the hypothesis of human sacrifice. I was unable to determine the status of the individuals deposited in the caves. The best interpretation is that several types of depositional activity occurred within these caves over time
Creating a GUI for Zori, a Quantum Monte Carlo Program
Rappture is a new GUI development kit that enables developers to build I/O interfaces for specific applications. In this article, the authors describe the Rappture toolkit's use in generating a GUI for the Zori computer code
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Syracuse University, School of Architecture
The work presented here is the product of a year-long process that is the culminating experience of a professional education in architecture. It is a process that stresses inquiry and product, research and design, writing and visualization. It has been along-established goal at Syracuse that the final efforts of both the undergraduate and graduate prgrams be indistinguishable from ont another; thus the mixture of undergraduate and graduate award winners.
Each student is advised by a committee of three and the final reviews are graded by a committee of five. Following the final reviews a panel of outside experts is invited to Superjury to see the best of the work. At the end of the day the entire faculty assembles to award the prizes that are recognized here.
The James A. Britton prizes for best thesis are awarded annually. The runner-up Dean\u27s Citations and Thesis Citations are awarded to all students participating in the Superjury.
-Bruce Abbey
Students:Yanel De Angel, M. Arch, Palio Ritual and Market Siena, ItalyGonzalo Diez, M. Arch, Rural school EcuadorRyan Dillon, B. Arch, Ansel Adams Gallery CaliforniaChristian Daniels, B. Arch, Virtual Dwelling Los Angeles, CaliforniaAmador Pons, B. Arch, Housing the Homeless New York, New YorkH. Philipp Walter, B. Arch, A Studio Gallery Addition to the Everson Museum of Art Syracuse, New YorkMaria Agostini, M. Arch, Carmelite Monastery Puerto RicoHeidi Christianson, B. Arch, Community Church, Well, and Market HaitiD. Jason Olsen, B. Arch, Digital Library and Community Archive New York, New YorkMaricel Ramos, M. Arch, Registration Center and Public Entry San Juan, Puerto RicoRyan Samsa, B. Arch, Urban Housing Rochester, New YorkJeffrey Zynda, INS Border Station Alexandria Bay, New Yor
Porque não comemos nossa saudável biodiversidade?
A balanced diet with fresh and natural foods is the basis of a healthy life. However, the Brazilian food base is poor, in terms of diversity, being constituted by many industrialized and multiprocessed foods, marketed in globalized markets.We are experiencing an ecological-environmental crisis, with changes in climate and degradation of natural resources and ecosystem services. These conditions force us to rethink production models that can, at the
same time, produce healthy food and preserve the productive base. In this work some native food species with potential for production and development of new socio-biodiversity value chains are presented, covering the discussion of this insertion being accompanied by a transition to more ecological, autonomous and resilient models of production, and with great alignment with the United Nations Sustainable Development Goals. A discussion is carried out between the potential of the insertion of these species and the limitations or obstacles to their advancement. There are a number of potential benefits, market insertion disseminates them to society, improves the resilience of agricultural production, and is quite suitable for family farming. Among the limitations and obstacles are the low knowledge that society has about biodiversity, the very low volume of scientific production on the production, use and management of native species, and a mismatch between the curricula of agricultural science courses in relation to the needs of present times, understood as Anthropocene. These factors will need to be overcome if we are to value biodiversity and appropriate practices for greater ecological and social balance.Uma alimentação equilibrada com alimentos frescos e naturais é a base de uma vida saudável, mas a dieta alimentar do brasileiro é pobre, em se tratando da diversidade, sendo constituída ainda por muitos alimentos industrializados e ultraprocessados, comercializados em mercados globalizados. A atual crise ecológica-ambiental, com alterações no clima e degradação dos recursos naturais e dos serviços ecossistêmicos, nos obriga a repensar a transformação dos atuais modelos de produção para que possam, ao mesmo tempo, produzir alimentos saudáveis e preservar sua base produtiva. Neste trabalho são apresentadas algumas espécies alimentares nativas com potencial para produção e desenvolvimento de novas cadeias de valor da sociobiodiversidade. Também é discutida uma transição para modelos mais ecológicos de produção, autônomos e resilientes, com alinhamento aos Objetivos do Desenvolvimento Sustentável, das Nações Unidas. Realiza-se, ainda, uma discussão entre o potencial da inserção destas espécies e as limitações ou entraves para seu avanço. Há uma série de potenciais benefícios, a inserção no mercado as divulga para a sociedade, melhoram a resiliência da produção agrícola e são bastante apropriadas para a agricultura familiar. Entre as limitações e entraves aponta-se o baixo conhecimento que a sociedade detém sobre a biodiversidade, o baixíssimo volume de produção científica sobre produção, uso e manejo das espécies nativas, e um descompasso entre os currículos dos cursos de ciências agrárias frentes as necessidades dos tempos atuais, entendido como antropoceno. Estes fatores precisarão ser superados se quisermos valorizar a biodiversidade e as práticas adequadas para maior equilíbrio ecológico e social
Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation.
The normally soluble TAR DNA-binding protein 43 (TDP-43) is found aggregated both in reversible stress granules and in irreversible pathogenic amyloid. In TDP-43, the low-complexity domain (LCD) is believed to be involved in both types of aggregation. To uncover the structural origins of these two modes of β-sheet-rich aggregation, we have determined ten structures of segments of the LCD of human TDP-43. Six of these segments form steric zippers characteristic of the spines of pathogenic amyloid fibrils; four others form LARKS, the labile amyloid-like interactions characteristic of protein hydrogels and proteins found in membraneless organelles, including stress granules. Supporting a hypothetical pathway from reversible to irreversible amyloid aggregation, we found that familial ALS variants of TDP-43 convert LARKS to irreversible aggregates. Our structures suggest how TDP-43 adopts both reversible and irreversible β-sheet aggregates and the role of mutation in the possible transition of reversible to irreversible pathogenic aggregation
Standardizing effect size from linear regression models with log-transformed variables for meta-analysis
Background: Meta-analysis is very useful to summarize the effect of a treatment or a risk factor for a given disease.
Often studies report results based on log-transformed variables in order to achieve the principal assumptions of a
linear regression model. If this is the case for some, but not all studies, the effects need to be homogenized.
Methods: We derived a set of formulae to transform absolute changes into relative ones, and vice versa, to allow
including all results in a meta-analysis. We applied our procedure to all possible combinations of log-transformed
independent or dependent variables. We also evaluated it in a simulation based on two variables either normally or
asymmetrically distributed.
Results: In all the scenarios, and based on different change criteria, the effect size estimated by the derived set of
formulae was equivalent to the real effect size. To avoid biased estimates of the effect, this procedure should be
used with caution in the case of independent variables with asymmetric distributions that significantly differ from
the normal distribution. We illustrate an application of this procedure by an application to a meta-analysis on the
potential effects on neurodevelopment in children exposed to arsenic and manganese.
Conclusions: The procedure proposed has been shown to be valid and capable of expressing the effect size of a
linear regression model based on different change criteria in the variables. Homogenizing the results from different
studies beforehand allows them to be combined in a meta-analysis, independently of whether the transformations
had been performed on the dependent and/or independent variables
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