Optical energies of AllnN epilayers

Optical energy gaps are measured for high-quality Al1−xInxN-on-GaN epilayers with a range of compositions around the lattice match point using photoluminescence and photoluminescence excitation spectroscopy. These data are combined with structural data to determine the compositional dependence of emission and absorption energies. The trend indicates a very large bowing parameter of 6 eV and differences with earlier reports are discussed. Very large Stokes' shifts of 0.4-0.8 eV are observed in the composition range 0.13<x<0.24, increasing approximately linearly with InN fraction despite the change of sign of the piezoelectric fiel

The Role of Creativity in Entrepreneurship

This paper evaluates the contribution of creativity to entrepreneurship theory and practice in terms of building an holistic and transdisciplinary understanding of its impact. Acknowledgement is made of the subjectivist theory of entrepreneurship which embraces randomness, uncertainty and ambiguity but these factors should then be embedded in wider business and social contexts. The analysis is synthesised into a number of themes, from consideration of its definition, its link with personality and cognitive style, creativity as a process and the use of biography in uncovering data on creative entrepreneurial behaviour. Other relevant areas of discussion include creativity&rsquo;s link with motivation, actualisation and innovation, as well as the interrogation of entrepreneurial artists as owner/managers. These factors are embedded in a critical evaluation of how creativity contributes to successful entrepreneurship practice. Modelling, measuring and testing entrepreneurial creativity are also considered and the paper includes detailed consideration of several models of creativity in entrepreneurship. Recommendations for future theory and practice are also made

Non-adherence to Mediterranean diet and synergy with lifestyle habits in the occurrence of breast cancer: a case-control study in Italy

Objective: The aim of this study was to assess the synergistic effect of non-adherence to the Mediterranean Diet (MD) and lifestyle habits on the occurrence of breast cancer (BC). Patients and methods: A case-control study was carried out from September 2018 to February 2019 at the Teaching Hospital "Umberto I" in Rome. A Food Frequency Questionnaire was used for assessing the level of adherence to MD, the IPAQ Questionnaire to measure physical activity, and AUDIT-C to estimate alcohol consumption. The possible interaction between risk factors was tested using the synergism index. Results: A total of 94 cases and 88 controls were enrolled (median age 55.8 for cases and 57.9 for controls). The MD Score over 6 was associated with low odds of having breast cancer (OR = 0.29; 95% CI: 0.12-0.69). There is a clear indication for the additivity and synergism between non-adherence to MD and many risk factors on the occurrence of BC: current smoker (S = 2.02; 95% CI 0.62-8.07), physical inactivity (S = 2.14; 95% CI 0.71 2-8.28) and alcohol consumption (S = 3.02; 95% CI 0.91-12.95). Conclusions: Primary prevention of BC can benefit from intervention targeting nutritional and lifestyle factors that act synergistically

Informes de avaliação de genótipos de girassol 2007/2008 e 2008.

Características Gerais da Rede de Ensaios de Avaliação de Genótipos de Girassol. Resultados dos Ensaios Finais de Primeiro e de Segundo Ano - safra 2007/2008 e safrinha 2008. Ensaio Final de Segundo Ano - safra 2007/2008: Encruzilhada do Sul (RS). Três de Maio (RS), Curitiba (PR), Leme do Prado (MG). Locais não considerados na análise conjunta. Análise conjunta. Ensaio Final de Primeiro Ano - safra 2007/2008: São Gabriel (RS), Santa Cruz do Sul (RS), Xaxim (SC), Jaguariúna (SP), Mocambinho (MG) Leme do Prado (MG), Roda Velha (BA), Ipanguaçú (RN). Locais não considerados na análise conjunta. Análise conjunta. Ensaio Final de Segundo Ano - safrinha 2008: Londrina (PR), Manduri (SP), Cravinhos (SP), Uberaba (MG), Muzambinho (MG), Rio Verde (GO), Planaltina (DF), Chapadão do Sul (MS), São José dos Quatro Marcos (MT), Campos de Julio (MT), Vilhena / Ensaio A (RO) Vilhena / Ensaio B (RO), Bom Jesus (PI). Locais não considerados na análise conjunta. Análise conjunta. Ensaio Final de Primeiro Ano - safrinha 2008: Londrina (PR), Jaboticabal (SP), Manduri (SP), Patos de Minas (MG), Planaltina (DF), Vilhena . Ensaio A (RO) Vilhena . Ensaio B (RO), Mata Roma (MA). Locais não considerados na análise conjunta. Análise conjunta. Lista dos genótipos de girassol avaliados e registrados no Ministério da Agricultura, Pecuária e Abastecimento - MAPA.bitstream/CNPSO-2010/30362/1/Doc316.pd

Informes da avaliação de genótipos de girassol 2008/2009 e 2009.

bitstream/item/40374/1/Doc320VE.pd

Informes da avaliação de genótipos de girassol 2008/2009 e 2009.

Esta publicação apresenta os resultados das avaliações da Rede de Ensaios de Avaliação de Genótipos de Girassol, realizadas em diferentes regiões edafoclimáticas do País.bitstream/CPAF-RO-2010/14590/1/Doc320VE.pd

Tissue immune profile: a tool to predict response to neoadjuvant therapy in triple negative breast cancer

Abstract: Pathological complete response (pCR) after neoadjuvant chemotherapy (NACT) can predict better survival outcomes in patients with early triple negative breast cancer (TNBC). Tumor infiltrating lymphocytes (TILs), Programmed Death-Ligand 1 (PD-L1), and Cluster of Differentiation 73 (CD73) are immune-related biomarkers that can be evaluated in the tumor microenvironment. We investigated if the contemporary expression of these biomarkers combined in a tissue immune profile (TIP) can predict pCR better than single biomarkers in TNBC. Tumor infiltrating lymphocytes (TILs), CD73 expression by cancer cells (CC), and PD-L1 expression by immune cells (IC) were evaluated on pre-NACT biopsies. We defined TIP positive (TIP+) as the simultaneous presence of TILS ≥ 50%, PD-L1 ≥ 1%, and CD73 ≤ 40%. To consider the effects of all significant variables on the pCR, multivariate analysis was performed. Akaike information criterion (AIC) and Bayesian information criterion (BIC) were used for model selection. We retrospectively analyzed 60 biopsies from patients with TNBC who received standard NACT. Pathological complete response was achieved in 23 patients (38.0%). Twelve (20.0%) cases resulted to be TIP+. The pCR rate was significantly different between TIP+ (91.7%) and TIP− (25.0%) (p &lt; 0.0001). Using a multivariate analysis, TIP was confirmed as an independent predictive factor of pCR (OR 49.7 (6.30–392.4), p &lt; 0.0001). Finally, we compared the efficacy of TIP versus each single biomarker in predicting pCR by AIC and BIC. The combined immune profile is more accurate in predicting pCR (AIC 68.3; BIC 74.5) as compared to single biomarkers. The association between TIP+ and pCR can be proposed as a novel link between immune background and response to chemotherapy in TNBC, highlighting the need to consider an immunological patients’ profile rather than single biomarkers

Creativity and Innovation under Constraints: A Cross-Disciplinary Integrative Review

Generating creative ideas and turning them into innovations is key for competitive advantage. However, endeavors toward creativity and innovation are bounded by constraints such as rules and regulations, deadlines, and scarce resources. The effect of constraints on creativity and innovation has attracted substantial interest across the fields of strategic management, entrepreneurship, industrial organization, technology and operations management, organizational behavior, and marketing. Research in these fie ds has focused on various constraints that trigger distinct mediating mechanisms but is fragmented and yields conflicting findings. We develop a taxonomy of constraints and mediating mechanisms and provide an integrative synthesis that explains how constraints impact creativity and innovation. Our review thus facilitates cross-disciplinary learning and sets the stage for further theoretical development

Chemical desiccants for anticipation of harvest and quality improvement of chickpea seeds.

ABSTRACT Desiccating herbicides can promote uniformity of maturation, and early harvest and provide improvements in the physical, physiological, and sanitary seeds quality. The objective of this work was to evaluate the use of herbicides in early harvest and in the physiological quality of chickpea seeds. The experimental design was of randomized blocks with four replications, considering a complete factorial design with one control (no application) + two factors (four herbicides x three different doses): glufosinate-ammonium (200, 400 and 500 g a.i./ha); diquat (200, 400 and 500 g a.i./ha); carfentrazoneethyl (15, 30 and 37.5 g a.i./ha) and saflufenacil (49, 98 and 122.5 g a.i./ha). Saflufenacil (49 g a.i./ha) showed the lowest harvest anticipation (4 days) and a low percentage of vigor (50.25%). Glufosinate (400 g a.i./ha), was the most promising as it increased germination to 83.75% and vigor to 78.25%, in addition to promoting the anticipation of harvest by up to 17 days, while the normal cycle of the crop, observed in the control, was 154 days.elocation e2506