Biblio-MetReS: A bibliometric network reconstruction application and server

<p>Abstract</p> <p>Background</p> <p>Reconstruction of genes and/or protein networks from automated analysis of the literature is one of the current targets of text mining in biomedical research. Some user-friendly tools already perform this analysis on precompiled databases of abstracts of scientific papers. Other tools allow <b>expert </b>users to elaborate and analyze the full content of a corpus of scientific documents. However, to our knowledge, no <b>user friendly </b>tool that simultaneously analyzes the latest set of scientific documents available on line and reconstructs the set of genes referenced in those documents is available.</p> <p>Results</p> <p>This article presents such a tool, Biblio-MetReS, and compares its functioning and results to those of other user-friendly applications (iHOP, STRING) that are widely used. Under similar conditions, Biblio-MetReS creates networks that are comparable to those of other user friendly tools. Furthermore, analysis of full text documents provides more complete reconstructions than those that result from using only the abstract of the document.</p> <p>Conclusions</p> <p>Literature-based automated network reconstruction is still far from providing complete reconstructions of molecular networks. However, its value as an auxiliary tool is high and it will increase as standards for reporting biological entities and relationships become more widely accepted and enforced. Biblio-MetReS is an application that can be downloaded from <url>http://metres.udl.cat/</url>. It provides an easy to use environment for researchers to reconstruct their networks of interest from an always up to date set of scientific documents.</p

O TRIBUNAL DO JÚRI: EVOLUÇÃO HISTÓRICA, ESTRUTURA E FUNCIONAMENTO

O presente artigo científico traz como objetivo geral, expor e discutir a evolução histórica do Tribunal do Júri, bem como sua estrutura e funcionamento. O método utilizado para o desenvolvimento e enriquecimento deste foi a pesquisa bibliográfica, utilizando ainda como embasamento legal o Código de Processo Penal de 1941, além da Constituição Federal de 1988. Através destas pesquisas foram evidenciados o rito do Tribunal do Júri, quem pode compô-lo, as garantias de um jurado, tal como suas atribuições e funções. Ao expor as considerações finais, são apresentados pontos que tratam a importância da existência e composição deste tribunal, bem como sua aplicabilidade contemporânea após as evoluções históricas

Família e vulnerabilidade social: um estudo com octogenários

In order to guide the development of dementia-related public policies for the elderly, it is important to identify factors that vary together with the social vulnerability of this population. This study aimed to identify the relationship between the São Paulo Social Vulnerability Index (IPVS) and various indicators of family support for elderly people over 80 years of age, who presented cognitive alterations (N=49). All ethical guidelines were followed. Data were collected at the homes of the elderly people. A large majority of the respondents lived with family members (88%). In half of the cases, the respondents lived with one (41%) or two (9%) other elderly persons. On average, there was one more non-elderly person living in the high vulnerability family context (M = 3.6, sd = 1.70) than in contexts of very low vulnerability (M = 2.4, sd = 1.07), F(2.43) = 3.364, p < 0.05. However, the functionality of the support provided by these family members needs to be verified, in each of these contexts.Para elaborar políticas públicas para el cuidado de anciano con demencia, es importante verificar factores que varían con la vulnerabilidad social de esa población. El objetivo de este estudio fue identificar la relación entre una medida de vulnerabilidad social (IPVS) y algunos indicadores de apoyo familiar para ancianos, con más de 80 años, con alteraciones cognitivas (N=49). Todas las recomendaciones éticas fueron observadas. Los datos fueron recolectados en los domicilios de los ancianos. La gran mayoría de los entrevistados vivía con la familia (88%). En la mitad de las familias los ancianos vivían con uno (41%) o dos ancianos (9%). En promedio había una persona más, que no era anciana, viviendo en el contexto familiar de alta vulnerabilidad (M=3,6, DE=1,70) que en el contexto de muy baja vulnerabilidad (M=2,4, DE=1,07), F (2, 43)=3,364, pPara direcionar políticas públicas para cuidado ao idoso com demência, é importante verificar fatores que variam com a vulnerabilidade social dessa população. O objetivo foi identificar a relação entre uma medida de vulnerabilidade social (IPVS) e alguns indicadores de apoio familiar para idosos acima de 80 anos, com alterações cognitivas (N=49). Todos os cuidados éticos foram observados. Os dados foram coletados nos domicílios dos idosos. A grande maioria dos entrevistados morava com a família (88%). Em metade das famílias os idosos moravam com mais um (41%) ou dois idosos (9%). Em média havia uma pessoa a mais, não idosa, morando no contexto familiar de alta vulnerabilidade (M=3,6, dp=1,70) do que no contexto de muito baixa vulnerabilidade (M=2,4, dp=1,07), F (2, 43)=3,364,

The distribution of rare metals in the LCT pegmatites from the Giraúl field, Angola

The Giraúl granitic pegmatite field, Angola, is composed of five pegmatite types; the most evolved belong to the beryl-columbite, beryl-columbite-phosphate and spodumene types. Pegmatites are concentrically zoned with increased grain size toward a quartz core; the most evolved pegmatites have well-developed replacement units. These pegmatites are rich in Nb-Ta oxide minerals and the field has a moderate interest for critical elements as Ta and Hf. Pegmatites are concentrically zoned with an increased grain size towards a quartz core. Tourmaline, garnet and beryl micas occur as accessory minerals. The abundance of Zr and Nb-Ta minerals increases with the evolution of the pegmatites, as well as the proportions of beryl and Li-rich minerals. The ; the Ta/(Ta+Nb) ratios in Nb-Ta oxide minerals and the Hf/(Hf+Zr) ratios in zircon also increase with the grade of evolution of the pegmatites and inside within each pegmatite body from border to inner zones, and especially in the late veins and subsolidus replacements. Textural patterns and occurrence of late veins with Ta-rich minerals suggest that Nb and especially Ta can be enriched in late hydrothermal exsolved fluids exsolved from the magma, along with Hf and other incompatible elements as Sn, U, Pb, Sb and Bi.Peer ReviewedPostprint (published version

BONE DENSITY GROWTH. BIOMECHANICS OF HEALTHY AND PROSTHETIC FEMUR AFTER A TOTAL HIP ARTHROPLASTY

The necessity of computational tools to predict the long-term behavior of bone implants and prosthetic devices in orthopedics, has a tremendous importance, considering population aging as a world wide problem. However, specifically in the hip prosthesis research area, the bone density growth process modeling using the finite element method (FEM) is still a challenging task. In this work, we investigate the bone density growth based on growth and remodeling theories for biological materials and its treatment using continuum mechanics. There are presented the kinematics, the balance laws for mass and linear momentum and the constitutive equations for bone density growth, along with the governing equations resulting from the coupling of the mass and momentum balances. We present an example considering the healthy and the prosthetic femur submitted to loads and bone formed by cortical and spongious tissues, which was carried out using daily physical activities load cases, for locate possible growth and resorption. In addition, a preliminary density growth model to locate bone growth or reabsorption zones for the intact femur and its post-operative condition is presented

Probing invisible neutrino decay with KM3NeT/ORCA

In the era of precision measurements of the neutrino oscillation parameters, upcoming neutrino experiments will also be sensitive to physics beyond the Standard Model. KM3NeT/ORCA is a neutrino detector optimised for measuring atmospheric neutrinos from a few GeV to around 100 GeV. In this paper, the sensitivity of the KM3NeT/ORCA detector to neutrino decay has been explored. A three-flavour neutrino oscillation scenario, where the third neutrino mass state ¿3 decays into an invisible state, e.g. a sterile neutrino, is considered. We find that KM3NeT/ORCA would be sensitive to invisible neutrino decays with 1/a3 = t3/m3 < 180 ps/eV at 90% confidence level, assuming true normal ordering. Finally, the impact of neutrino decay on the precision of KM3NeT/ORCA measurements for ¿23, ¿m231 and mass ordering have been studied. No significant effect of neutrino decay on the sensitivity to these measurements has been found.Article signat per 255 autors i autores: S. Aiello, A. Albert, S. Alves Garre, Z. Aly, A. Ambrosone, F. Ameli, M. Andre, M. Anghinolfi, M. Anguita, M. Ardid, S. Ardid, J. Aublin, C. Bagatelas, L. Bailly-Salins, B. Baret, S. Basegmez du Pree, Y. Becherini, M. Bendahman, F. Benfenati, E. Berbee, V. Bertin, S. Biagi, M. Boettcher, M. Bou Cabo, J. Boumaaza, M. Bouta, M. Bouwhuis, C. Bozza, H.Brânzaş, R. Bruijn, J. Brunner, R. Bruno, E. Buis, R. Buompane, J. Busto, B. Caiffi, D. Calvo, S. Campion, A. Capone, F. Carenini, V. Carretero, P. Castaldi, S. Celli, L. Cerisy, M. Chabab, N. Chau, A. Chen, R. Cherkaoui El Moursli, S. Cherubini, V. Chiarella, T. Chiarusi, M. Circella, R. Cocimano, J. A. B. Coelho, A. Coleiro, R. Coniglione, P. Coyle, A. Creusot, A. Cruz, G. Cuttone, R. Dallier, Y. Darras, A. De Benedittis, B. De Martino, V. Decoene, R. Del Burgo, I. Di Palma, A. F. Díaz, D. Diego-Tortosa, C. Distefano, A. Domi, C. Donzaud, D. Dornic, M. Dörr, E. Drakopoulou, D. Drouhin, T. Eberl, A. Eddyamoui, T. van Eeden, M. Eff, D. van Eijk, I. El Bojaddaini, S. El Hedri, A. Enzenhöfer, V. Espinosa, G. Ferrara, M. D. Filipović, F. Filippini, L. A. Fusco, J. Gabriel, T. Gal, J. García Méndez, A. Garcia Soto, F. Garufi, C. Gatius Oliver, N. Geißelbrecht, L. Gialanella, E. Giorgio, A. Girardi , I. Goos, S. R. Gozzini, R. Gracia, K. Graf, D. Guderian, C. Guidi, B. Guillon, M. Gutiérrez, L. Haegel, H. van Haren, A. Heijboer, A. Hekalo, L. Hennig, J. J. Hernández-Rey, F. Huang, W. Idrissi Ibnsalih, G. Illuminati, C. W. James, D. Janezashvili, M. de Jong, P. de Jong, B. J. Jung, P. Kalaczyński, O. Kalekin, U. F. Katz, N. R. Khan Chowdhury, G. Kistauri, F. van der Knaap, P. Kooijman, A. Kouchner, V. Kulikovskiy, M. Labalme, R. Lahmann, A. Lakhal, M. Lamoureux, G. Larosa, C. Lastoria, A. Lazo, R. Le Breton, S. Le Stum, G. Lehaut, E. Leonora, N. Lessing, G. Levi, S. Liang, M. Lindsey Clark, F. Longhitano, L. Maderer, J. Majumdar, J. Mańczak, A. Margiotta, A. Marinelli, C. Markou, L. Martin, J. A. Martìnez-Mora, A. Martini, F. Marzaioli, M. Mastrodicasa, S. Mastroianni, K. W. Melis, S. Miccichè, G. Miele, P. Migliozzi, E. Migneco, P. Mijakowski, C. M. Mollo, L. Morales-Gallegos, C. Morley-Wong, A. Moussa, R. Muller, M. R. Musone, M. Musumeci, L. Nauta, S. Navas, C. A. Nicolau, B. Nkosi, B. Ó Fearraigh, A. Orlando, E. Oukacha, J. Palacios González, G. Papalashvili, R. Papaleo, E.J. Pastor Gomez, A. M. Păun, G. E. Păvălaş, C. Pellegrino, S. Peña Martínez, M. Perrin-Terrin, J. Perronnel, V. Pestel, P. Piattelli, O. Pisanti, C. Poirè, V. Popa, T. Pradier, S. Pulvirenti, G. Quéméner, U. Rahaman, N. Randazzo, S. Razzaque, I. C. Rea, D. Real, S. Reck, G. Riccobene, J. Robinson, A. Romanov, F. Salesa Greus, D. F. E. Samtleben, A. Sánchez Losa, M. Sanguineti, C. Santonastaso, D. Santonocito, P. Sapienza, A. Sathe, J. Schnabel, M. F. Schneider, J. Schumann, H. M. Schutte, J. Seneca, I. Sgura, R. Shanidze, A. Sharma, A. Simonelli, A. Sinopoulou, M.V. Smirnov, B. Spisso, M. Spurio, D. Stavropoulos, S. M. Stellacci, M. Taiuti, K. Tavzarashvili, Y. Tayalati, H. Tedjditi, T. Thakore, H. Thiersen, S. Tsagkli, V. Tsourapis, E. Tzamariudaki, V. Van Elewyck, G. Vannoye, G. Vasileiadis, F. Versari, S. Viola, D. Vivolo, H. Warnhofer, J. Wilms, E. de Wolf, H. Yepes-Ramirez, T. Yousfi, S. Zavatarelli, A. Zegarelli, D. Zito, J. D. Zornoza, J. Zúñiga, N. ZywuckaPostprint (published version

KM3NeT broadcast optical data transport system

The optical data transport system of the KM3NeT neutrino telescope at the bottom of the Mediterranean Sea will provide more than 6000 optical modules in the detector arrays with a point-to-point optical connection to the control stations onshore. The ARCA and ORCA detectors of KM3NeT are being installed at a depth of about 3500 m and 2500 m, respectively and their distance to the control stations is about 100 kilometers and 40 kilometers. In particular, the two detectors are optimised for the detection of cosmic neutrinos with energies above about 1 TeV (ARCA) and for the detection of atmospheric neutrinos with energies in the range 1 GeV–1 TeV (ORCA). The expected maximum data rate is 200 Mbps per optical module. The implemented optical data transport system matches the layouts of the networks of electro-optical cables and junction boxes in the deep sea. For efficient use of the fibres in the system the technology of Dense Wavelength Division Multiplexing is applied. The performance of the optical system in terms of measured bit error rates, optical budget are presented. The next steps in the implementation of the system are also discussed.Peer ReviewedArticle signat per 254 autors/es: L. Bailly-Salins, B. Baret, S. Basegmez du Pree, Y. Becherini, M. Bendahman, F. Benfenati, E. Berbee, V. Bertin, S. Biagi, M. Boettcher, M. Bou Cabo, J. Boumaaza, M. Bouta, M. Bouwhuis, C. Bozza, H. Brânzaş, R. Bruijn, Brunner, R. Bruno, E. Buis, R. Buompane, J. Busto, B. Caiffi, D. Calvo, S. Campion, A. Capone, F. Carenini, V. Carretero, P. Castaldi, S. Celli, L. Cerisy, M. Chabab, N. Chau, A. Chen, R. Cherkaoui El Moursli, S. Cherubini, V. Chiarella, T. Chiarusi, M. Circella, R. Cocimano, J.A.B. Coelho, A. Coleiro, R. Coniglione, P. Coyle, A. Creusot, A. Cruz, G. Cuttone, A. D’Amico, R. Dallier, Y. Darras, A. De Benedittis, B. De Martino, R. Del Burgo, I. Di Palma, A.F. Díaz, D. Diego-Tortosa, C. Distefano, A. Domi, C. Donzaud, D. Dornic, M. Dörr, E. Drakopoulou, D. Drouhin, T. Eberl, A. Eddyamoui, T. van Eeden, M. Eff, D. van Eijk,I. El Bojaddaini, S. El Hedri, A. Enzenhöfer, V. Espinosa, G. Ferrara, M.D. Filipović, F. Filippini, L.A. Fusco, J. Gabriel, T. Gal, J. García Méndez, A. Garcia Soto, F. Garufi, C. Gatius Oliver, N. Geißelbrecht, L. Gialanella, E. Giorgio, A. Girardi, I. Goos, S.R. Gozzini, R. Gracia, K. Graf, D. Guderian, C. Guidi, B. Guillon, M. Gutiérrez, L. Haegel, H. van Haren, A. Heijboer, A. Hekalo, L. Hennig, J.J. Hernández-Rey, F. Huang, W. Idrissi Ibnsalih, G. Illuminati, C.W. James, D. Janezashvili, M. de Jong, P. de Jong, B.J. Jung, P. Kalaczyński, O. Kalekin, U.F. Katz, N.R. Khan Chowdhury, G. Kistauri, F. van der Knaap, P. Kooijman, A. Kouchner, V. Kulikovskiy, M. Labalme, R. Lahmann, A. Lakhal, M. Lamoureux, G. Larosa, C. Lastoria, A. Lazo, R. Le Breton, S. Le Stum, G. Lehaut, E. Leonora, N. Lessing, G. Levi, S. Liang, M. Lindsey Clark, F. Longhitano, L. Maderer, J. Majumdar, J. Mańczak, A. Margiotta, A. Marinelli, C. Markou, L. Martin, J.A. Martínez-Mora, A. Martini, F. Marzaioli, M. Mastrodicasa, S. Mastroianni, K.W. Melis, S. Miccichè, G. Miele, P. Migliozzi, E. Migneco, P. Mijakowski, C.M. Mollo, L. Morales-Gallegos, C. Morley-Wong, A. Moussa, R. Muller, M.R. Musone, M. Musumeci, L. Nauta, S. Navas, C.A. Nicolau, B. Nkosi, B. Ó Fearraigh, A. Orlando, E. Oukacha, J. Palacios González, G. Papalashvili, R. Papaleo, E.J. Pastor Gomez, A.M. Păun, G.E. Păvălaş, C. Pellegrino, S. Peña Martínez, M. Perrin-Terrin, J. Perronnel, V. Pestel, P. Piattelli, O. Pisanti, C. Poirè, V. Popa, T. Pradier, S. Pulvirenti, G. Quéméner, U. Rahaman, N. Randazzo, S. Razzaque, I.C. Rea, D. Real, S. Reck, G. Riccobene, J. Robinson, A. Romanov, F. Salesa Greus, D.F.E. Samtleben, A. Sánchez Losa, M. Sanguineti, C. Santonastaso, D. Santonocito, P. Sapienza, A. Sathe, J. Schmelling, J. Schnabel, M.F. Schneider, J. Schumann, H. M. Schutte, J. Seneca, I. Sgura, R. Shanidze, A. Sharma, A. Simonelli, A. Sinopoulou, M.V. Smirnov, B. Spisso, M. Spurio, D. Stavropoulos, S.M. Stellacci, M. Taiuti, K. Tavzarashvili, Y. Tayalati, H. Tedjditi, H. Thiersen, S. Tsagkli, V. Tsourapis, E. Tzamariudaki, V. Van Elewyck, G. Vannoye, G. Vasileiadis, F. Versari, S. Viola, D. Vivolo, H. Warnhofer, J. Wilms, E. de Wolf, H. Yepes-Ramirez, T. Yousfi, S. Zavatarelli, A. Zegarelli, D. Zito, J.D. Zornoza, J. Zúñiga and N. ZywuckaPostprint (published version