The Influence of Different Nonsteroidal Anti-Inflammatory Drugs on Alveolar Bone in Rats: An Experimental Study

Svrha ovog istraživanja bila je proučiti učinak deksketoprofen-trometamola, meloksikama i natrijeva diklofenaka na netretiranu alveolarnu kost kada se koriste lijekovi za neku drugu indikaciju. Materijali i metode: Dvadeset osam mužjaka štakora Spraque-Dawley randomizirano je u četiri grupe na sličan način: tretirani su deksketoprofen-trometamolom (grupa 1.), meloksikamom (grupa 2.) i natrijevim diklofenakom (grupa 3.), a u kontrolnoj grupi nije se primjenjivao nikakav lijek. Nesteroidne protuupalne lijekove (NSAID) dobivali su deset dana nakon frakture fibule. Netretiranoj alveolarnoj kosti histopatološki se procjenjivala gustoća spongiozne kosti te osteoklastična i osteoblastična gustoća. Rezultati: Gustoća spongiozne kosti bila je niža u eksperimentalnim grupama (grupe od 1 do 3) negoli u kontrolnoj (p < 0,05). Suprotno tome, u eksperimentalnim grupama uočeno je povećanje gustoće osteoklasta u odnosu prema kontrolnoj grupi (p < 0,05). Prema gustoći osteoblasta grupe 2 i 3 bile su niže od kontrolne (p < 0,05), ali je u grupi 1 gustoća bila ista kao i u kontrolnoj. Zaključak: Ovo istraživanje pokazalo je da sustavno korištenje NSAID-a može utjecati na netretiranu alveolarnu kost. To se treba uzeti u obzir u slučaju produljenog korištenja tih lijekova.The aim: The aim of this study was to investigate the effect of dexketoprofen trometamol, meloxicam, diclofenac sodium on any untreated alveolar bone when they are used as drugs for another indication. Materials and Methods: Twenty eight male Spraque-Dawley rats were randomized into four groups as dexketoprofen trometamol (Group I), meloxicam (Group II), diclofenac sodium (Group III) and control group. Nonsteroidal anti-inflammatory drugs (NSAID) were administered after a fibula fracture for 10 days. Untreated alveolar bone was histopathologically examined for spongious bone density, osteoclastic density and osteoblastic density. Results: Spongious bone density was lower in study groups (Group I, group II and group III) than the control group (p<0.05). In contrast, the increase in osteoclastic density was observed in other groups apart from the control group (p<0.05). Osteoblastic density was evaluated and it was determined that group II and group III had lower results than the control group (p<0.05) but group I was equal to the control group. Conclusion: This study showed that systemically administrated NSAIDs have the potential to affect untreated alveolar bone. This should also be considered in long term use of NSAIDs

Cronotopías del mandato familiar en novelas argentinas de la postdictadura

Nuestro trabajo actual de investigación se desenvuelve en torno al problema de novelas argentinas contemporáneas que tematizan el período de la dictadura militar (1976-1983). Para trabajar metódicamente este corpus en gestación apelamos a la noción de cronotopía bajtiniana, categoría generadora de relatos que ordenan diferentes formas de la experiencia humana y regulan la aparición de sujetos y discursos identitarios. En este artículo desarrollamos una breve serie que llamamos "cronotopía del mandato familiar" y en la que los jóvenes protagonistas sufren diferentes aprendizajes y pruebas vinculadas con los acontecimientos de la dictadura que los convierten en sujetos alienados, mutilados o escindidos.Our present work focuses on the investigation of contemporary Argentinean novels that deal with the period of the military dictatorship (1976-1983). In order to work metodologically on this corpus in progress, we appeal to the notion of the so-called Bachtinian chronotopy, generating category of stories which organize different forms for the human experiences and regulate the emergency of subjects and identity speeches. In this article we develop a brief series referred as the "chronotopy of the family mandate", in which young protagonists go through various learning experiences and tests related to the happenings of a terrible time that render them into alienated and exscinded subjects

Effects of wheel traffic and farmyard manure applications on soil CO2 emission and soil oxygen content

This 2-year field study investigated the effects of different wheel traffic passes, manure amounts, and manure application methods on soil temperature, soil moisture, CO2 emission, and soil O2 content. To achieve this purpose, three different wheel traffic applications (no traffic, one pass, and two passes) were used. In the experiments, two different methods of manure applications (surface and subsurface) and three different farmyard manure amounts were used with a control plot (N0), 40 Mg ha-1 (N40), and 80 Mg ha-1(N80). Manure was applied in both years of the experiment in the first week of April. For the subsurface application, the manure was mixed in at approximately 10 cm of soil depth with a rotary tiller. According to the results, soil temperature, soil moisture, penetration resistance, and bulk density increased with increasing wheel traffic except CO2 emission for 2014 and 2015. CO2 emission values decreased with traffic. Subsurface manure application caused more CO2 emission compared to surface application. The increase in manure amounts led to an increase in CO2 emission and soil moisture content. The effects on soil O2 content were observed only during 2015. Maximum oxygen values were obtained in the plots where compaction was not applied. In addition, surface manure application caused more soil O2 content compared to subsurface application. © TÜBİTAK

The effects of reduced tillage and compaction level on the red lentil yield

A two year - field experiment was conducted to investigate the effects of three tillage treatments and three intra-row compaction levels on sowing performance, weed population, red lentil yield and yield components. The tillage treatments were: (1) conventional tillage (moldboard plow + disk harrow + float - CT); (2) reduced tillage 1 (horizontal axis rotary tiller - RT1); (3) reduced tillage 2 (vertical axis rotary tiller with roller - RT2). Intra-row compaction levels were: (1) no compaction (C0), (2) 60 kPa compaction (C1) and (3) 90 kPa compaction (C2). Results concluded that reduced tillage systems provided the best results of sowing performance and weed density. However, the highest crop yield was observed at the plot with tilled conventional tillage systems. Additionally, the increase in the intra-row compaction level improved sowing performance and crop yields

Modeling air pollution levels in volcanic geological regional properties and microclimatic conditions

Air pollution was predicted in this study by using multiple linear regression and 42 different artificial neural network models in Iğdır/Turkey. Daily air quality data for the years 2016–2018 have been used in the modeling. In the prediction of the particulate matter which has 10 µm or less in diameter (PM10) concentration, sulfur dioxide, nitrogen oxides, nitrogen monoxide, ozone, nitrogen dioxide, relative humidity, air pressure, wind direction and wind speed data were used as input parameters. In the artificial neural network structures, two different learning functions, three different transfer functions and seven different neuron numbers were examined in the MATLAB software. According to results, multiple linear regression did not predict the PM10 concentration in the atmosphere. The R2 value was determined as 0.543 for the multiple linear regression. In this model, the RMSE, MAE and R2 were determined as 0.0488, 0.0248 and 0.9826, respectively. Since the R2 value in this model was quite high, it was concluded that the model is suitable for the prediction of PM10 concentration. © 2020, Islamic Azad University (IAU)

Effects of strip width and tractor forward speed on sowing uniformity of maize and sunflower

A two year - field experiment was conducted to investigate the effects of strip width and tractor forward speed on sowing uniformity of maize and sunflower. Being equipped to achieve purpose of this study, a row crop rotary hoe with C-type blades was used to obtain different strip widths. During the experiment, the field area was tilled in 22.5, 30 and 37.5 cm wide strips, respectively; these widths were obtained by changing the positions of flanges and blade connections of the rotary hoe. The rotary hoe was operated at a constant rotor rotation speed of 370 min-1, in a tillage depth of 10 cm and at 3 different tractor forward speeds (1.8, 3.6 and 5.4 km h-1) in order to get various soil fragmentation values. Because of increasing the forward speed during the tillage, coefficient variations of sowing depth uniformity, intra and inter-row seed distribution uniformity and seed distribution area for both maize and sunflower seeds decreased. The precision of the distribution of the seeds along the length of the row for the forward speeds was well below 29%; and therefore, it was acceptable for both maize and sunflower seeds. However, the strip width did not have a significant effect on the sowing performance parameters. Tractor forward speed became effective on soil fragmentation, and accordingly the distribution of smaller soil particles decreased with the increase in the speed. This study demonstrated that the most acceptable tractor forward speed for the strip tillage method in terms of the sowing uniformity parameters was 1.8 km h-1 for all of the experiment years

Physico-mechanical and some chemical properties of apricot varieties in iğdır province [Iğdır ili kayısı çeşitlerinin fiziko-mekanik ve bazı kimyasal özellikleri**]

In this research it was determined physical, mechanical and some chemical properties of Şalak, Ordubat and Teberze apricot varieties, grown in Iğdır province. At the Şalak variety the values of dimension, weight, rupture force, bulk density and true density were found higher compare the other varieties. The highest friction value was obtained in Teberze variety. The lowest and the highest friction coefficient were observed at the galvanized sheet and plastic surface, respectively. In addition, the Ordubat variety had the most water soluble dry matter and the lowest pH value. © 2019, Centenary University. All rights reserved

Differentiation in Gravimetrical and Frictional Properties of Phaseolus Vulgaris L. by a Partial Least Square Regression Model

WOS: 000471239900018This study was conducted to determine gravimetrical and frictional properties of four white kidney beans varieties (Karaman, Topcu, Karacasehir and Akman), each having five different seed moisture contents (14.58 %, 24.32 %, 33.45 %. 42.54 % and 53.48 %). According to obtained results, the axial dimensions of all bean varieties increased by increasing the seed moisture content. In addition, there was a positive relationship between the thousand grain mass and seed moisture content and bet ween the surface area and moisture content. The seed bulk densities negatively correlated with the seed moisture content. A partial least. square regression (PLSR) model included all parameters successfully differentiated the varieties into 3 independent groups: Akman and Topcu were in the same group (group 1), and each of Karacasehir (group 2) and Goynuk (group 3) varieties significantly differed from all varieties. The result of PLSR score plot significantly differentiated the five different water contents of the seeds: the seeds with 25%, 35% and 45% moisture content. were in the same group. It was concluded that both the grain water content and the grain variety had significant effects on engineering properties

The effects of tillage and intra-row compaction on seedbed properties and red lentil emergence under dry land conditions

WOS: 000291774300001A two year-field experiment was conducted to investigate the effects of three tillage treatments and three intra-row compaction levels on physical properties of seedbed and red lentil emergence in dry soil condition. The tillage treatments were: (1) conventional tillage (moldboard plow + disk harrow + float CT); (2) reduced tillage 1 (horizontal axis rotary tiller - RT1); (3) reduced tillage 2 (vertical axis rotary tiller with roller - RT2). Intra-row compaction levels were: (1) no compaction (CO), (2)60 kPa compaction (C1) and (3) 90 kPa compaction (C2). Tillage systems and intra-row compaction levels had significant effects on seedbed properties and seed emergence. In both years, while the maximum aggregate size observed using the RT1 system was between 1 and 8 mm, the CT system caused the highest MWD. The RT1 tillage system and C2 compaction level had a tendency of giving higher water holding capacity and water availability. RT2 and C2 treatments caused higher cone indexes and bulk density values than RT1 and CT. CT and CO levels tend to decrease the cone index and bulk density at the top layer of soil. The only factor affected by soil tillage systems in both years was the mean emergence time (MET). For both growing seasons, the highest MET was found in CT and the lowest in RT2 and RT1 tillage systems. However, soil tillage systems and intra-row compaction levels both affected the percentage of seedling emergence (PE). While plots tilled with RT2 produced the maximum PE, the CT tillage system illustrated the minimum. Intra row compaction clearly enhanced PE values. (C) 2011 Elsevier B.V. All rights reserved