5,279 research outputs found
In re Executive Assignment of State Attorney, 298 So. 2d 382 (Fla. 1974)
Grand Juries- CHIEF JUSTICE MAY SUSPEND GRAND JURY INVESTIGATIONS THAT INTERFERE WITH CONSTITUTIONAL DUTIES OF LEGISLATIVE AND EXECUTIVE BRANCHES
A General, But Readily Adaptable Model of Information System Risk
This article is the first of two whose goal is to advance the discussion of IS risk by addressing limitations of the current IS risk literature. These limitations include: inconsistent or unclear definitions of risk, limited applicability of risk models, frequent omission of the temporal nature of risk, and lack of an easily communicated organizing framework for risk factors. This article presents a general, but broadly adaptable model of system-related risk. The companion article, (CAIS Volume 14, Article 2) focuses on IS risk factors and how these factors can be organized. This article starts by identifying criteria for a general, but broadly applicable risk model. It compares alternative conceptualizations of risk and provides clarifications of the definitions of risk and of different treatments of goals, expectations, and baselines for assessing risk. It presents several of the risk models in the IS literature and discusses the temporal nature of risk. Based on that background it presents a general and broadly adaptable model of risk that encompasses: goals and expectations, risk factors and other sources of uncertainty, the operation of the system or project whose risks are being managed, the risk management effort, the possible outcomes and their probabilities, impacts on other systems, and the resulting financial gains or losses. The model\u27s adaptability allows users to eliminate facets that are not important for their purposes. For example, the majority of current practitioners would probably think of risk in terms of negative outcomes rather than the full distribution of possible outcomes. A comparison of the general model with other risk models in the IS literature shows that it covers most of the ideas expressed by previous IS risk models while also providing a practical approach that managers can use for thinking about IS risk at whatever level of detail makes sense to them
Information Systems Risks and Risk Factors: Are They Mostly About Information Systems?
This article is the second of two whose goal is to advance the discussion of IS risk by addressing limitations of the current IS risk literature. The first article (CAIS Volume 14, Article 1)presented a general, but broadly adaptable model of system-related risk that addressed the limited usefulness of existing IS risk models for business managers. In this article, we focus on organizing risk factors to make them more useful and meaningful for business managers. This article shows how the nine elements of the work system framework can be used to organize the hundreds of risk factors in the IS risk literature. It also shows that many of the most important and most commonly cited risk factors for IS in operation and IS projects are actually risk factors for work systems in general. Furthermore, risk factors initially associated with one type of system (e.g. ERP implementation) are often equally relevant at other levels (e.g., information systems projects or work systems in general). Over half of the risk factors in a representative sample of the IS risk literature are valid for work systems in general. This conclusion is a step toward useful risk diagnostic tools based on an organized set of risk factors that are meaningful to business managers and IT professionals
The effects of temperature gradient and growth rate on the morphology and fatigue properties of MAR-M246(Hf)
MAR-M246(Hf) is a nickel based superalloy used in the turbopump blades of the Space Shuttle main engines. The effects are considered of temperature gradient (G) and growth rate (R) on the microstructure and fatigue properties of this superalloy. The primary dendrite arm spacings were found to be inversely proportional to both temperature gradient and growth rate. Carbide and gamma - gamma prime morphology trends were related to G/R ratios. Weibull analysis of fatigue results shows the characteristic life to be larger by a factor of 10 for the low gradient/fast rate pairing of G and R, while the reliability (beta) was lower
Bone mineral density in patients with inherited bone marrow failure syndromes.
BackgroundPatients with inherited bone marrow failure syndromes (IBMFS) may have several risk factors for low bone mineral density (BMD). We aimed to evaluate the prevalence of low BMD in IBMFS and determine the associated risk factors.MethodsPatients with IBMFS with at least one dual-energy X-ray absorptiometry (DXA) scan were evaluated. Diagnosis of each IBMFS, Fanconi anemia (FA), dyskeratosis congenita, Diamond-Blackfan anemia, and Shwachman-Diamond syndrome was confirmed by syndrome-specific tests. Data were gathered on age, height, and clinical history. DXA scans were completed at the lumbar spine, femoral neck, and forearm. BMD was adjusted for height (HAZ) in children (age ≤20 years). Low BMD was defined as a BMD Z-score and HAZ ≤-2 in adults and children, respectively, in addition to patients currently on bisphosphonate therapy.ResultsNine of thirty-five adults (26%) and eleven of forty children (27%) had low BMD. Adults with FA had significantly lower BMD Z-scores than those with other diagnoses; however, HAZ did not vary significantly in children by diagnosis. Risk factors included hypogonadism, iron overload, and glucocorticoid use.ConclusionsAdults and children with IBMFS have high prevalence of low BMD. Prompt recognition of risk factors and management are essential to optimize bone health
Clear and Convincing to Whom the False Claims Act and Its Burden of Proof Standard: Why the Government Needs a Big Stick
Clear and Convincing to Whom the False Claims Act and Its Burden of Proof Standard: Why the Government Needs a Big Stick
Allowable Trajectory Variations for Space Shuttle Orbiter Entry-Aeroheating CFD
Reynolds-number criteria are developed for acceptable variations in Space Shuttle Orbiter entry trajectories for use in computational aeroheating analyses. The criteria determine if an existing computational fluid dynamics solution for a particular trajectory can be extrapolated to a different trajectory. The criteria development begins by estimating uncertainties for seventeen types of computational aeroheating data, such as boundary layer thickness, at exact trajectory conditions. For each type of datum, the allowable uncertainty contribution due to trajectory variation is set to be half of the value of the estimated exact-trajectory uncertainty. Then, for the twelve highest-priority datum types, Reynolds-number relations between trajectory variation and output uncertainty are determined. From these relations the criteria are established for the maximum allowable trajectory variations. The most restrictive criterion allows a 25% variation in Reynolds number at constant Mach number between trajectories
P10-03. Dramatic changes in Fc-receptor expression during HIV-1 infection associated with reduced phagocytic activity during progressive HIV-1 infection
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