Very late periprosthetic joint infection: etiological agents and outcomes of two stage revision

The main aim of the current study is to evaluate the success of two-stage revision surgery in very late periprosthetic joint infection (PJI). The second aim was to identify the causative etiological agents and to rank these pathogens according to their incidence. Twenty-seven patients (16 THA and 11 TKA) who were operated on with two-stage revision arthroplasty due to very late PJI (>60 months after primary arthroplasty) were included in our study. Demographic information of the patients, operation site, follow-up period, time from the first spacer application to the second stage revision, number of spacer replacement surgeries, duration of infection, presence of fistula, presence of recurrence after second stage arthroplasty and complications were noted. Preoperative and last follow-up Knee Society and Harris Hip Scores were calculated. The success of two-stage revision surgery was evaluated statistically. The causative etiological agents were ranked according to their incidence. The age of the patients at the time of first stage revision ranged from 24 to 94 years, with a mean age of 57.9±15.7. Infection recurrence was 18.75% in the very late hip and 27.3% in the very late knee PJI group. There was a statistically significant increase in postoperative Knee Society and Harris Hip Scores (p [Med-Science 2023; 12(3.000): 700-9

Competitive Environment Hypothesis in Turkish Banking System

TThis paper investigates the persistence of profit in Turkish banking system for the period of 2004:1 – 2009:4 by focusing net income after tax to total equity (ROE) as profit measures by utilizing panel unit root tests. We found that competition among surviving banks is high in the Turkish Banking System for the period 2004:1 – 2009:4 which means that competitive environment hypothesis is valid in Turkish banking system.Persistence, ROE, Turkish Banking System

A Single Clone Acinetobacter baumannii Outbreak in a State Hospital in Turkey

ERTURK, AYSE/0000-0001-6413-9165WOS: 000320094900014PubMed: 23698489Acinetobacter baumannii is an important pathogen in hospitalized patients, particularly those in the intensive care unit (ICU). A total of 21 A. baumannii (6 from 5 patients and 15 from environmental samples) were isolated in the ICU and the isolation room of a state hospital in June 2011. The possible source of the outbreak was investigated. A. baumannii isolates were identified using conventional biochemical tests, BBL Crystal Identification Systems, OXA-51 specific PCR, and 16S rDNA sequencing. All the isolates were multidrug-resistant, showing resistance to cephalosporins, carbapenems, fluoroquinolones, and the aminoglycoside group of antibiotics. Pulsed-field gel electrophoresis suggested that all A. baumannii isolates were derived from a common source

Synchronous and metachronous bilateral breast cancer: A long-term experience

WOS: 000451018200005PubMed ID: 30610782Purpose: The objective of this study was to assess the demographic, pathologic and survival characteristics of patients who were diagnosed as having bilateral breast cancer. Methods: A review was conducted of the records pertaining to patients who presented to our clinic and were diagnosed as having breast cancer. Any second cancer diagnosed within 12 months of initial diagnosis was defined as synchronous bilateral breast cancer. Assessment included treatments administered to the patients and survival rates, as well as their demographic, reproductive and pathologic features. Results: The total number of patients who were diagnosed as having bilateral breast cancer in the context of the present study was 99. Among the patients with synchronous breast cancer, the median age at the time of initial diagnosis was found as 57 years. The median age of the discovery of first tumor among the patients with metachronous tumor was 52 years and the median age of second tumor detection was 59 years. Family history in metachronous tumor was significantly greater (p =0.041). The median time of metachronous cancer incidence was 96 months. The length of disease-free period among the patients with synchronous tumor was 126.3 months, whereas it was 243.7 months in those with metachronous tumor (p=0.041). Conclusion: The incidence rate of synchronous breast tumors has been rising thanks to growing awareness and the leading-edge imaging methods. The fact that the second tumor developed after more than 5 years among the patients with metachronous cancer gave rise to the increased rate of survival

An investigation of the effects of total hip arthroplasty with femoral shortening in unilateral Crowe type-IV dysplastic hips on sagittal spinopelvic parameters

It has been reported that sagittal spinal alignment may become abnormal in patients with hip osteoarthritis. There is limited data in the literature on how spinopelvic parameters change after total hip arthroplasty (THA) with femoral shortening in unilateral Crowe type IV dysplastic hips. We aimed to investigate the effects of THA with femoral shortening in unilateral Crowe type IV dysplastic hips on sagittal spinopelvic parametres. Patients who underwent THA for Crowe type IV dysplastic hips at our institution between 2014-2019 were included in the study. Pre- and postsurgical standing anteroposterior and lateral spine X-Ray images of the each patient were uploaded to SURGIMAP© (Nemaris Inc.. USA) (https://www.surgimap.com/). The radiographic data of all patients were reviewed and measurements performed for each patient by two senior spinal surgeons. All of the parameters were retrieved from the SURGIMAP© measurement system. There were 18 patients aged 27-60 (mean, 45.5±7.9) years. The mean follow-up duration was 27.5 ± 8.9 (range, 13–42) months. There was no statistically difference between pre-and postoperative values of Sacral Slope (SS), Pelvic incidence (PI) Lumbar Lordosis (LL), PI-LL mismatch and Thoracic Kyphosis (TK), Global Tilt (GT), T1 Pelvic Angle (TPA), Cervical Lordosis (CL) and T1 slope (T1S). We also found no significant change between pre-and postsurgical values of global alignment and proportion (GAP) scores. The only significant change was in detected pre-and postsurgical values of PT, T1Spi, T9Spi ( p = 0.022, p = 0.035, and p = 0.033 respectively). THA with femoral shortening in unilateral Crowe type-IV dysplastic hips does not effect a change in sagittal spinopelvic parameters. Except for PT, T9SPi, and T1SPi do. [Med-Science 2022; 11(2.000): 734-9

The impact of new generation oxygenators with integrated arterial filters on neurological outcome

Conclusion: Membrane oxygenators with integrated arterial filters do not seem to offer a significant advantage over those without integrated arterial filters in terms of neurocognitive outcomes in patients undergoing coronary artery bypass grafting

Outcomes of Mild to Moderate Functional Tricuspid Regurgitation in Patients Undergoing Mitral Valve Operations: A Meta-Analysis of 2,488 Patients

This meta-analysis examined the prognosis of patients who were found to have mild to moderate functional tricuspid regurgitation during mitral valve operations. Overall, this meta-analysis included 2,488 patients in 10 studies. Compared with the group without tricuspid valve annuloplasty, the probability of not progressing to moderate to severe functional tricuspid regurgitation was significantly higher in the tricuspid valve annuloplasty group. A more aggressive surgical approach involving concomitant tricuspid repair with mitral valve operations may be considered to avoid the development of moderate to severe functional tricuspid regurgitation in the follow-up. (C) 2015 by The Society of Thoracic Surgeon

Chronomodulated oxaliplatin plus Capecitabine (XELOX) as a first line chemotherapy in metastatic colorectal cancer: A Phase II Brunch regimen study

The aim of this study was to evaluate safety and toxicity of chronomodulated capecitabine administered in the morning and at noon according to a specific time schedule (Brunch Regimen: Breakfast and Lunch) as a part of first-line XELOX chemotherapy in patients with metastatic colorectal cancer